Mapping pharmaceuticals in tissues using MALDI imaging mass spectrometry

Journal of Pharmacological and Toxicological Methods

Volumn 55, Issue 2, 2007, Pages 193-200

  Hsieh, Yunsheng ^a   Chen, Jiwen ^a   Korfmacher, Walter A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Imaging mass spectrometry; MALDI; Pharmaceuticals; Tissue samples

Indexed keywords

ACETYLCHOLINE; ALPHA CYANO 4 HYDROXYCINNAMIC ACID; BENZODIAZEPINE DERIVATIVE; CELLULOSE; CLOZAPINE; DOPA; DRUG METABOLITE; ENZYME; KETOCONAZOLE; NEW DRUG; NORCLOZAPINE; OLANZAPINE; PACLITAXEL; PHOSPHOLIPID; PROPRANOLOL; SCH 206272; SCH 226374; SCH 412348; SHAMPOO; SODIUM CHLORIDE; SPIPERONE; UNCLASSIFIED DRUG; VITAMIN; XENOBIOTIC AGENT;

ARTICLE; BIOTRANSFORMATION; DRUG DETERMINATION; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; DRUG TRANSFORMATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOTOPE LABELING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION; WHOLE BODY AUTORADIOGRAPHY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG EVALUATION, PRECLINICAL; MICE; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RATS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 33846886098     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2006.06.004     Document Type: Article

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