Binge ethanol-induced HDAC3 down-regulates Cpt1α expression leading to hepatic steatosis and injury

Alcoholism: Clinical and Experimental Research

Volumn 37, Issue 11, 2013, Pages 1920-1929

  Kirpich, Irina ^a,b   Zhang, Jingwen ^a   Gobejishvili, Leila ^a,b   Kharebava, Giorgi ^a   Barker, David ^a   Ghare, Smita ^a,b   Joshi Barve, Swati ^a,b   Mcclain, Craig J ^a,b,c   Barve, Shirish ^a,b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Binge Alcohol Exposure; CPT1 ; HDAC3; Liver Steatosis

Indexed keywords

ALCOHOL; HISTONE DEACETYLASE 3; HISTONE H3; LYSINE; MESSENGER RNA; TRICHOSTATIN A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINGE DRINKING; CARNITINE PALMITOYLTRANSFERASE IALPHA GENE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME INHIBITION; EPIGENETICS; FATTY LIVER; GENE; GENE EXPRESSION; HISTONE ACETYLATION; HUMAN; HUMAN CELL; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; TRANSCRIPTION REGULATION;

MUS;

BINGE ALCOHOL EXPOSURE; CPT1Α; HDAC3; LIVER STEATOSIS;

ANIMALS; BINGE DRINKING; CARNITINE O-PALMITOYLTRANSFERASE; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DOWN-REGULATION; DRUG-INDUCED LIVER INJURY; ETHANOL; FATTY LIVER; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTONE DEACETYLASES; MALE; MICE; MICE, INBRED C57BL;

EID: 84886439819     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/acer.12172     Document Type: Article

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