Involvement of histone acetyltransferase (HAT) in ethanol-induced acetylation of histone H3 in hepatocytes: Potential mechanism for gene expression

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 289, Issue 6 52-6, 2005, Pages

  Park, Pil Hoon ^a   Lim, Robert W ^a   Shukla, Shivendra D ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

c Jun NH2 terminal kinase; Ethanol metabolism; Extracellular signal regulated kinase; Selective acetylation

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ALCOHOL; ALCOHOL DEHYDROGENASE; ALCOHOL DEHYDROGENASE I; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; HISTONE ACETYLTRANSFERASE; HISTONE H3; LYSINE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME SPECIFICITY; GENE EXPRESSION REGULATION; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TRANSCRIPTION INITIATION;

ACETYLATION; ALCOHOL DEHYDROGENASE; ANIMALS; ANTHRACENES; BUTADIENES; ETHANOL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; HISTONE ACETYLTRANSFERASES; HISTONES; IMIDAZOLES; MALE; MAP KINASE SIGNALING SYSTEM; NITRILES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 28444450531     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00091.2005     Document Type: Article

References (56)

1. Ait-Si-Ali S, Carlisi D, Ramirez S, Upegui-Gonzalez LC, Duquet A, Robin PR, Rudkin B, Harel-Bellan A, and Trouche D. Phosphorylation by p44 MAP kinase/ERK1 stimulates CBP histone acetyl transferase activity in vitro. Biochem Biophys Res Commun 262: 157-162, 1999.
2. Allfrey V, Faulkner RM, and Mirsky AE. Acetylation and methylation of histones and their possible role in the regulation of RNA synthesis. Proc Natl Acad Sci USA 51: 786-794, 1964.
3. Aroor AR and Shukla SD. MAP kinase signaling in diverse effects of ethanol. Life Sci 74: 2339-2364, 2004.
4. Badger T, Hoog JO, Svensson S, McGehee RE, Fang C, Ronis MJJJ, and Ingelman-Sundberg M. Cyclic expression of class I alcohol dehydrogenase in male rats treated with ethanol. Biochem Biophys Res Commun 274: 684-688, 2000.
5. Bjerling P, Silverstein RA, Thon G, Caudy A, Grewal S, and Ekwall K. Functional divergence between histone deacetylases in fission yeast by distinct cellular localization and in vivo specificity. Mol Cell Biol 22: 2170-2181, 2002.
6. Bonner WM, West MHP, and Stedman JD. Two-dimensional gel analysis of histones in acid extracts of nuclei, cells, and tissues. Eur J Biochem 109: 17-23, 1980.
7. Bosron WF, Magnes LJ, and Li TK. Kinectic and electrophoretic properties of native and recombined isoenzymes of human liver alcohol dehydrogenase. Biochemistry 22: 1952-1857, 1983.
8. Cao Q, Mak KM, and Lieber CS. Dilinoleoylphosphatidylcholine decreases acetaldehyde-induced TNF-alpha generation in Kuffer cells of ethanol-fed rats. Biochem Biophys Res Commun 299: 459-464, 2002.
9. Carson EJ and Prutt SB. Development and characterization of a binge drinking model in mice for evaluation of the immunological effects of ethanol. Alcohol Clin Exp Res 20: 132-138, 1996.
10. Chen JP, Ishac EN, Dent P, Kunos G, and Gao B. Effects of ethanol on mitogen-activated protein kinase and stress-activated protein kinase cascades in normal and regenerating liver. Biochem J 334: 669-676, 1998.
11. Cheung P, Allis CD, and Sassone-Corsi P. Signaling to chromatin through histone modifications. Cell 103: 263-271, 2000.
12. Clayton AL and Mahadevan LC. MAP kinase-mediated phosphoacetylation of histone H3 and inducible gene regulation. FEBS Lett 546: 51-58, 2003.
13. Deaciuc IV, Doherty DE, Burikhanov R, Lee EY, Stromberg AJ, Peng X, and De villiers WJS. Large-scale gene profiling of the liver in a mouse model of chronic, intragastric ethanol infusion. J Hepatol 40: 219-227, 2004.
14. Gong P, Cedervaum AI, and Nieto N. Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. J Biol Chem 278: 29693-29700, 2003.
15. Gordon AS, Collier K, and Diamond I. Ethanol regulation of adenosine receptor-stimulated cAMP levels in a cloned cell line: an in vitro model of cellular tolerance to ethanol. Proc Natl Acad Sci USA 83: 2105-2108, 1986.
16. Grunstein M. Histone acetylation in chromatin structure and transcription. Nature 389: 349-352, 1997.
17. Hansen JC, Tse C, and Wolffe AP. Structure and function of the core histone N-termini: more than meets the eye. Biochemistry 37: 17637-17641, 1998.
18. Ho YF and Guenthner TM. Isolation of liver nuclei that retain functional trans-membrane transport. J Pharmacol Toxicol Methods 38: 163-168, 1997.
19. Jenuwein T and Allis CD. Translating the histone code. Science 293: 1074-1080, 2001.
20. Kawasaki H, Schiltz L, Chiu R, Itakura K, Taira K, and Yokoyama KK. ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation. Nature 405: 195-200, 2000.
21. Koch A, Giembycz M, Ito K, Lim S, Jazrawi E, Barnes PJ, Adcock I, Erdmann E, and Chung KF. Mitogen-activated protein kinase modulation of nuclear factor-kappaB-induced granulocyte macrophage-colony-stimulating factor release from human alveolar macrophages. Am J Respir Cell Mol Biol 30: 342-349, 2004.
22. Kuo MH and Allis CD. Roles of histone acetyltransferases and deacetylases in gene regulation. Bioessays 20: 615-626, 1998.
23. Kyosseva SV. Mitogen-activated protein kinase signaling. Int Rev Neurobiol 59: 201-220, 2004.
24. Lands WEM. Cellular signals in alcohol-induced liver injury: a review. Alcohol Clin Exp Res 19: 928-938, 1995.
25. Lee YJ and Shukla SD. Pro- and anti- apoptotic roles of c-Jun N-terminal (JNK) in ethanol and acetaldehyde exposed rat hepatocytes. Eur J Pharmacol 508: 31-45, 2005.
26. Marks PA, Richon VM, Breslow R, and Rifkind RA. Histone deacetylase inhibitors as new cancer drugs. Curr Opin Oncol 13: 477-483, 2001.
27. Mei S, Ho AD, and Mahlknecht U. Role of histone deacetylase inhibitors in the treatment of cancer, Int J Oncol 25: 1509-1519, 2004.
28. Merienne K, Pannetier S, Harel-Bellan A, and Sassone-Corsi P. Mitogen-regulated RSK2-CBP interaction controls their kinase and acetylase activities. Mol Cell Biol 21: 7089-7096, 2001.
29. Minana JB, Gomez-Cambronero L, Lloret A, Pallardo FV, Del Olmo J, Escudero A, Rodrigo JM, Pelliin A, Vina JR, Vina J, and Sastre J. Mitochondrial oxidative stress and CD95 ligand: a dual mechanism for hepatocyte apoptosis in chronic alcoholism. Hepatology 35: 1205-1214, 2000.
30. Mistilis SP and Birchall A. Induction of alcohol dehydrogenase in the rat. Nature 223: 199-200, 1969.
31. Miyata Y, Towatari M, Maeda T, Ozawa Y, and Saito H. Histone acetylation induced by granulocyte colony-stimulating factor in a MAP kinase-dependent manner. Biochem Biophys Res Commun 283: 655-660, 2001.
32. Morgan K, French SW, and Morgan TR. Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage. Hepatology 36: 122-134, 2002.
33. Morimoto M, Hagbjorg AL, Nanji AA, Ingelman-Sundberg M, Lindros KO, and Fu PC. Role of cytochrome P450 2E1 in alcohol liver disease pathogenesis. Alcohol 10: 49-464, 1993.
34. Morinobu A, Kanno Y, and O'nd Shea JJ. Discrete roles for histone acetylation in human T helper 1 cell-specific gene expression. J Biol Chem 279: 40640-40646, 2004.
35. Nanji AA, Jokelainen K, Rahemtulla A, Miao L, and Fogt F. Activation of nuclear factor κB and cytokine imbalance in experimental alcoholic liver disease in the rat. Hepatology 30: 934-943, 1999.
36. 2+ concentration in isolated rat liver nuclei. Proc Natl Acad Sci USA 86: 453-457, 1989.
37. Ogryzko VV. Mammalian histone acetyltransferases and their complexes. Cell Mol Life Sci 58: 683-692, 2001.
38. Park GY, Joo M, Pedchenko T, Blackwell TS, and Christman JW. Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. Am J Physiol Lung Cell Mol Physiol 286: L956-L962, 2004.
39. Park PH, Miller R, and Shukla SD. Acetylation of histone H3 at lysine 9 by ethanol in rat hepatocytes. Biochem Biophys Res Commun 306: 501-504, 2003.
40. Rashid A, Wu T, Huang C, Chen C, Lin HZ, and Diehl AM. Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver. Hepatology 29: 1131-1138, 1999.
41. Rogakou EP, Redon C, Boon C, Johnson K, and Booner WM. Rapid histone extraction for electrophoretic analysis. Biotechniques 28: 38-46, 2000.
42. Ruijter AJ, Gennip AH, Caron HN, Kemp S, and Kuilenburg AB. Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem J 370: 737-749, 2003.
43. Sambucetti LC, Fischer DD, Zabludoff S, Kwon PO, Chamberlin H, Trogani N, Xu H, and Cohen D. Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects. J Biol Chem 274: 34940-34947, 1999.
44. Spitzer JA, Zheng M, Kolls JK, Vande Stouwe C, and Spitzer JJ. Ethanol and LPS modulate NF-κB activation, inducible NO synthase and COX-2 gene expression in rat liver cells in vivo. Front Biosci 7: 99-108, 2002.
45. Strahl BD and Allis CD. The language of covalent histone modifications. Nature 403: 41-45, 2000.
46. Struhl K. Histone acetylation and transcriptional regulatory mechanisms. Genes Dev 12: 599-606, 1998.
47. Tadic SD, Elm MS, Li HS, Van Londen GJ, Subbotin VM, Whitcomb DC, and Eagon PK. Sex differences in hepatic gene expression in a rat model of ethanol-induced liver injury. J Appl Physiol 93: 1057-1068, 2002.
48. Turner BM. Histone acetylation and an epigenetic code. Bioessays 22: 836-845, 2000.
49. Ugarte G and Iturriaga H. Metabolic pathways of alcohol in the liver. Front Gastrointest Res 2: 150-193, 1976.
50. Wang XD, Liu C, Chung J, Stickel F, Seitz HK, and Russel BM. Chronic alcohol intake reduces retinoic acid concentration and enhances AP-I expression in rat liver. Hepatology 28: 744-750, 1998.
51. Weng YI and Shukla SD. Ethanol alters angiotensin II stimulated mitogen activated protein kinase in hepatocytes: agonist selectivity and ethanol metabolic independence, Eur J Pharmacol 398: 323-331, 2000.
52. Weng YI and Shukla SD. Angiotensin II activation of focal adhesion kinase and pp60c-Src in relation to mitogen-activated protein kinases in hepatocytes. Biochim Biophys Acta 1589: 285-297, 2002.
53. Wolffe AP. Chromatin: Structure and Function (3rd ed.). San Diego, CA: Academic, 1998.
54. Wu D and Cederbaum AI. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity. J Biol Chem 278: 1115-1124, 2003.
55. Yamashita H, Kaneyuki T, and Tagawa K. Production of acetate in the liver and its utilization in peripheral tissues. Biochim Biophys Acta 1532: 79-87, 2002.
56. Zhou Z, Sun X, and Kang YJ. Ethanol-induced apoptosis in mouse liver: Fas- and cytochrome c-mediated caspase-3 activation pathway. Am J Pathol 159: 329-338, 2001.