Toward analogues of MraY natural inhibitors: Synthesis of 5′-triazole-substituted-aminoribosyl uridines through a Cu-catalyzed azide-alkyne cycloaddition

Journal of Organic Chemistry

Volumn 78, Issue 20, 2013, Pages 10088-10105

  Fer, Mickaël J ^a   Olatunji, Samir ^b   Bouhss, Ahmed ^b   Calvet Vitale, Sandrine ^a   Gravier Pelletier, Christine ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b Institut de Biochimie et Biophysique Moléculaire et Cellulaire   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINORIBOSE; AZIDE-ALKYNE CYCLOADDITION; CHEMICAL DIVERSITY; O-GLYCOSYLATION; STRAIGHTFORWARD STRATEGY; TERMINAL ALKYNE;

CATALYSIS; IODINE; NITROGEN COMPOUNDS; SCAFFOLDS;

HYDROCARBONS;

1 AZIDO 2 (4 BIPHENYLYL)ETHANE; 1 AZIDO 3 PHENYLPROPANE; 1 AZIDO 5 MORPHOLINOPENTANE; 1 AZIDO 5 PHTHALIMIDOPENTANE; 1 AZIDODECANE; 1 AZIDOPENTAN 5 OL; 1 AZIDOPROPAN 3 OL; 1,5 DIMETHANESULFONYLPENTANE; 4 (10 AZIDODECANYLOXY)BENZOPHENONE; 4 (3 AZIDOPROPYLOXY)BENZOPHENONE; 4 (4 AZIDOETHYLBENZYLOXY)BENZOPHENONE; 4 (5 AZIDOPENTYLOXY)BENZOPHENONE; ALKYNE DERIVATIVE; AMINORIBOSYLURIDINE DERIVATIVE; AZIDE; BACTERIAL ENZYME; CAPRAZAMYCIN B; CYCLOHEPTYLAZIDE; ENZYME INHIBITOR; FR 900493; LIPOSIDOMYCIN B; LIPOSIDOMYCIN C; MRAY INHIBITOR; MURAYMYCIN A1; MURAYMYCIN A2; MURAYMYCIN A3; MURAYMYCIN B1; MURAYMYCIN C1; UNCLASSIFIED DRUG; UNINDEXED DRUG; URIDINE DERIVATIVE;

ARTICLE; BACILLUS SUBTILIS; CATALYSIS; CATALYST; CHEMICAL BOND; CHEMICAL PROCEDURES; CONTROLLED STUDY; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; GLYCOSYLATION; IC 50; NONHUMAN; REACTION ANALYSIS; REPRODUCIBILITY; SUBSTITUTION REACTION;

ALKYNES; ANTI-BACTERIAL AGENTS; AZIDES; BACTERIAL PROTEINS; CATALYSIS; COPPER; CYCLOADDITION REACTION; DRUG RESISTANCE, BACTERIAL; ENZYME INHIBITORS; GLYCOSYLATION; TRANSFERASES; TRIAZOLES; URIDINE;

EID: 84886430232     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo4014035     Document Type: Article

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