Muraymycins, novel peptidoglycan biosynthesis inhibitors: Semisynthesis and SAR of their derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 12, Issue 17, 2002, Pages 2341-2344

  Lin, Yang I ^a   Li, Zhong ^a   Francisco, Gerardo D ^a   McDonald, Leonard A ^a   Davis, Rachel A ^a   Singh, Guy ^a   Yang, Youjun ^a   Mansour, Tarek S ^a  

^a WYETH RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; DRUG DERIVATIVE; MRAY PROTEIN, BACTERIA; MURAYMYCIN A1; MURAYMYCIN A3; MURAYMYCIN C1; NUCLEOTIDE; PEPTIDE; PEPTIDOGLYCAN; TRANSFERASE; UREA; MURAYMYCIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CELL WALL; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HYDROPHOBICITY; STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE ACTIVITY RELATION; SYNTHESIS; ULTRASTRUCTURE; ANTIMICROBIAL ACTIVITY; CONTROLLED STUDY; CORRELATION ANALYSIS; LIPOPHILICITY; NONHUMAN;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CELL WALL; HYDROPHOBICITY; NUCLEOTIDES; PEPTIDES; PEPTIDOGLYCAN; STAPHYLOCOCCUS EPIDERMIDIS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFERASES; UREA;

EID: 0037009244     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00469-9     Document Type: Article

References (12)