메뉴 건너뛰기




Volumn 9, Issue 8, 2013, Pages 1181-1191

Angelica sinensis polysaccharide nanoparticles as novel non-viral carriers for gene delivery to mesenchymal stem cells

Author keywords

Mesenchymal stem cells; Nanoparticle; Non viral vector; Polyethylenimine; Polysaccharide

Indexed keywords

LOW MOLECULAR WEIGHT; MESENCHYMAL STEM CELL; NONVIRAL VECTORS; POLYETHYLENIMINES; SEMI-QUANTITATIVE RT-PCR; SPHERICAL NANOPARTICLES; TRANSFECTION EFFICIENCY; TRANSFORMING GROWTH FACTOR BETA;

EID: 84886414012     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2013.05.008     Document Type: Article
Times cited : (50)

References (47)
  • 1
    • 77950384133 scopus 로고    scopus 로고
    • CD4+ FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice
    • Miao C.H., Harmeling B.R., Ziegler S.F., Yen B.C., Torgerson T., Chen L., et al. CD4+ FOXP3+ regulatory T cells confer long-term regulation of factor VIII-specific immune responses in plasmid-mediated gene therapy-treated hemophilia mice. Blood 2009, 114(19):4034-4044.
    • (2009) Blood , vol.114 , Issue.19 , pp. 4034-4044
    • Miao, C.H.1    Harmeling, B.R.2    Ziegler, S.F.3    Yen, B.C.4    Torgerson, T.5    Chen, L.6
  • 2
    • 67650679365 scopus 로고    scopus 로고
    • Non-viral vectors in cystic fibrosis gene therapy: recent developments and future prospects
    • Pringle I., Hyde S., Gill D. Non-viral vectors in cystic fibrosis gene therapy: recent developments and future prospects. Expert Opin Biol Ther 2009, 9:991-1003.
    • (2009) Expert Opin Biol Ther , vol.9 , pp. 991-1003
    • Pringle, I.1    Hyde, S.2    Gill, D.3
  • 4
    • 84865270609 scopus 로고    scopus 로고
    • Correction of brain oligodendrocytes by AAVrh. 10 intracerebral gene therapy in metachromatic leukodystrophy mice
    • Piguet F., Sondhi D., Piraud M., Fouquet F., Hackett N.R., Ahouansou O., et al. Correction of brain oligodendrocytes by AAVrh. 10 intracerebral gene therapy in metachromatic leukodystrophy mice. Hum Gene Ther 2012, 23:903-914.
    • (2012) Hum Gene Ther , vol.23 , pp. 903-914
    • Piguet, F.1    Sondhi, D.2    Piraud, M.3    Fouquet, F.4    Hackett, N.R.5    Ahouansou, O.6
  • 5
    • 37549032712 scopus 로고    scopus 로고
    • Breaking the bonds: non-viral vectors become chemically dynamic
    • Wolff J.A., Rozema D.B. Breaking the bonds: non-viral vectors become chemically dynamic. Mol Ther 2007, 16(1):8-15.
    • (2007) Mol Ther , vol.16 , Issue.1 , pp. 8-15
    • Wolff, J.A.1    Rozema, D.B.2
  • 6
    • 33847036990 scopus 로고    scopus 로고
    • Strategies for silencing human disease using RNA interference
    • Kim D.H., Rossi J.J. Strategies for silencing human disease using RNA interference. Nat Rev Genet 2007, 8(3):173-184.
    • (2007) Nat Rev Genet , vol.8 , Issue.3 , pp. 173-184
    • Kim, D.H.1    Rossi, J.J.2
  • 8
    • 82055176787 scopus 로고    scopus 로고
    • Development of liposomes and pseudovirions with fusion activity for efficient gene delivery
    • Kaneda Y. Development of liposomes and pseudovirions with fusion activity for efficient gene delivery. Curr Gene Ther 2011, 11(6):434-441.
    • (2011) Curr Gene Ther , vol.11 , Issue.6 , pp. 434-441
    • Kaneda, Y.1
  • 9
    • 84856515432 scopus 로고    scopus 로고
    • Phase 1 Gene therapy for duchenne muscular dystrophy using a translational optimized AAV vector
    • Bowles D.E., McPhee S.W.J., Li C., Gray S.J., Samulski J.J., Camp A.S., et al. Phase 1 Gene therapy for duchenne muscular dystrophy using a translational optimized AAV vector. Mol Ther 2011, 20(2):443-455.
    • (2011) Mol Ther , vol.20 , Issue.2 , pp. 443-455
    • Bowles, D.E.1    McPhee, S.W.J.2    Li, C.3    Gray, S.J.4    Samulski, J.J.5    Camp, A.S.6
  • 10
    • 77949327872 scopus 로고    scopus 로고
    • Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils
    • Kang E.M., Choi U., Theobald N., Linton G., Priel D.A.L., Kuhns D., et al. Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils. Blood 2010, 115(4):783-791.
    • (2010) Blood , vol.115 , Issue.4 , pp. 783-791
    • Kang, E.M.1    Choi, U.2    Theobald, N.3    Linton, G.4    Priel, D.A.L.5    Kuhns, D.6
  • 11
    • 0033959447 scopus 로고    scopus 로고
    • Cancer gene therapy: hard lessons and new courses
    • Vile R., Russell S., Lemoine N. Cancer gene therapy: hard lessons and new courses. Gene Ther 2000, 7(1):2.
    • (2000) Gene Ther , vol.7 , Issue.1 , pp. 2
    • Vile, R.1    Russell, S.2    Lemoine, N.3
  • 12
    • 77953251302 scopus 로고    scopus 로고
    • Viral vectors for gene transfer: current status of gene therapeutics
    • Heilbronn R., Weger S. Viral vectors for gene transfer: current status of gene therapeutics. Drug Deliv 2010, 197:143-170.
    • (2010) Drug Deliv , vol.197 , pp. 143-170
    • Heilbronn, R.1    Weger, S.2
  • 13
    • 0347355380 scopus 로고    scopus 로고
    • Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy
    • Mansouri S., Lavigne P., Corsi K., Benderdour M., Beaumont E., Fernandes J.C. Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy. Eur J Pharm Biopharm 2004, 57(1):1-8.
    • (2004) Eur J Pharm Biopharm , vol.57 , Issue.1 , pp. 1-8
    • Mansouri, S.1    Lavigne, P.2    Corsi, K.3    Benderdour, M.4    Beaumont, E.5    Fernandes, J.C.6
  • 14
    • 73449101112 scopus 로고    scopus 로고
    • Recent trends in non-viral vector-mediated gene delivery
    • Pathak A., Patnaik S., Gupta K.C. Recent trends in non-viral vector-mediated gene delivery. Biotechnol J 2009, 4(11):1559-1572.
    • (2009) Biotechnol J , vol.4 , Issue.11 , pp. 1559-1572
    • Pathak, A.1    Patnaik, S.2    Gupta, K.C.3
  • 15
    • 33947263729 scopus 로고    scopus 로고
    • Poly (ethylene glycol)-modified thiolated gelatin nanoparticles for glutathione-responsive intracellular DNA delivery
    • Kommareddy S., Amiji M. Poly (ethylene glycol)-modified thiolated gelatin nanoparticles for glutathione-responsive intracellular DNA delivery. Nanomed Nanotechnol Biol Med 2007, 3(1):32-42.
    • (2007) Nanomed Nanotechnol Biol Med , vol.3 , Issue.1 , pp. 32-42
    • Kommareddy, S.1    Amiji, M.2
  • 16
    • 79951686783 scopus 로고    scopus 로고
    • Non-viral gene delivery to mesenchymal stem cells: methods, strategies and application in bone tissue engineering and regeneration
    • Santos J.L., Pandita D., Rodrigues J., Pêgo A.P., Granja P.L., Tomás H. Non-viral gene delivery to mesenchymal stem cells: methods, strategies and application in bone tissue engineering and regeneration. Curr Gene Ther 2011, 11(1):46-57.
    • (2011) Curr Gene Ther , vol.11 , Issue.1 , pp. 46-57
    • Santos, J.L.1    Pandita, D.2    Rodrigues, J.3    Pêgo, A.P.4    Granja, P.L.5    Tomás, H.6
  • 19
    • 34247181222 scopus 로고    scopus 로고
    • Gene delivery by cationic lipid vectors: overcoming cellular barriers
    • Zuhorn I.S., Engberts J.B.F.N., Hoekstra D. Gene delivery by cationic lipid vectors: overcoming cellular barriers. Eur Biophys J 2007, 36(4):349-362.
    • (2007) Eur Biophys J , vol.36 , Issue.4 , pp. 349-362
    • Zuhorn, I.S.1    Engberts, J.B.F.N.2    Hoekstra, D.3
  • 20
    • 64149107875 scopus 로고    scopus 로고
    • Star-shaped cationic polymers by atom transfer radical polymerization from β-cyclodextrin cores for nonviral gene delivery
    • Xu F., Zhang Z., Ping Y., Li J., Kang E., Neoh K. Star-shaped cationic polymers by atom transfer radical polymerization from β-cyclodextrin cores for nonviral gene delivery. Biomacromolecules 2009, 10(2):285-293.
    • (2009) Biomacromolecules , vol.10 , Issue.2 , pp. 285-293
    • Xu, F.1    Zhang, Z.2    Ping, Y.3    Li, J.4    Kang, E.5    Neoh, K.6
  • 21
    • 34247523833 scopus 로고    scopus 로고
    • Cationic star polymers consisting of α-cyclodextrin core and oligoethylenimine arms as nonviral gene delivery vectors
    • Yang C., Li H., Goh S.H., Li J. Cationic star polymers consisting of α-cyclodextrin core and oligoethylenimine arms as nonviral gene delivery vectors. Biomaterials 2007, 28(21):3245-3254.
    • (2007) Biomaterials , vol.28 , Issue.21 , pp. 3245-3254
    • Yang, C.1    Li, H.2    Goh, S.H.3    Li, J.4
  • 22
    • 14044272234 scopus 로고    scopus 로고
    • Structure/property studies of polymeric gene delivery using a library of poly (β-amino esters)
    • Anderson D.G., Akinc A., Hossain N., Langer R. Structure/property studies of polymeric gene delivery using a library of poly (β-amino esters). Mol Ther 2005, 11(3):426-434.
    • (2005) Mol Ther , vol.11 , Issue.3 , pp. 426-434
    • Anderson, D.G.1    Akinc, A.2    Hossain, N.3    Langer, R.4
  • 23
    • 33746438424 scopus 로고    scopus 로고
    • Toxicity of cationic lipids and cationic polymers in gene delivery
    • Lv H., Zhang S., Wang B., Cui S., Yan J. Toxicity of cationic lipids and cationic polymers in gene delivery. J Control Release 2006, 114(1):100-109.
    • (2006) J Control Release , vol.114 , Issue.1 , pp. 100-109
    • Lv, H.1    Zhang, S.2    Wang, B.3    Cui, S.4    Yan, J.5
  • 25
    • 61549115627 scopus 로고    scopus 로고
    • Ternary complexes of pDNA, polyethylenimine, and γ-polyglutamic acid for gene delivery systems
    • Kurosaki T., Kitahara T., Fumoto S., Nishida K., Nakamura J., Niidome T., et al. Ternary complexes of pDNA, polyethylenimine, and γ-polyglutamic acid for gene delivery systems. Biomaterials 2009, 30(14):2846-2853.
    • (2009) Biomaterials , vol.30 , Issue.14 , pp. 2846-2853
    • Kurosaki, T.1    Kitahara, T.2    Fumoto, S.3    Nishida, K.4    Nakamura, J.5    Niidome, T.6
  • 26
    • 77958170934 scopus 로고    scopus 로고
    • Novel reduction-responsive cross-linked polyethylenimine derivatives by click chemistry for nonviral gene delivery
    • Liu J., Jiang X., Xu L., Wang X., Hennink W.E., Zhuo R. Novel reduction-responsive cross-linked polyethylenimine derivatives by click chemistry for nonviral gene delivery. Bioconjug Chem 2010, 21:1827-1835.
    • (2010) Bioconjug Chem , vol.21 , pp. 1827-1835
    • Liu, J.1    Jiang, X.2    Xu, L.3    Wang, X.4    Hennink, W.E.5    Zhuo, R.6
  • 27
    • 73449101442 scopus 로고    scopus 로고
    • Degradable poly (amino ester) based on poly (ethylene glycol) dimethacrylate and polyethylenimine as a gene carrier: molecular weight of PEI affects transfection efficiency
    • Yu J.H., Quan J.S., Huang J., Nah J.W., Cho C.S. Degradable poly (amino ester) based on poly (ethylene glycol) dimethacrylate and polyethylenimine as a gene carrier: molecular weight of PEI affects transfection efficiency. J Mater Sci Mater Med 2009, 20(12):2501-2510.
    • (2009) J Mater Sci Mater Med , vol.20 , Issue.12 , pp. 2501-2510
    • Yu, J.H.1    Quan, J.S.2    Huang, J.3    Nah, J.W.4    Cho, C.S.5
  • 28
    • 19444372923 scopus 로고    scopus 로고
    • A two-stage poly (ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy
    • Moghimi S.M., Symonds P., Murray J.C., Hunter A.C., Debska G., Szewczyk A. A two-stage poly (ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy. Mol Ther 2005, 11(6):990-995.
    • (2005) Mol Ther , vol.11 , Issue.6 , pp. 990-995
    • Moghimi, S.M.1    Symonds, P.2    Murray, J.C.3    Hunter, A.C.4    Debska, G.5    Szewczyk, A.6
  • 29
    • 0032892476 scopus 로고    scopus 로고
    • Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle
    • Godbey W.T., Wu K.K., Mikos A.G. Size matters: molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle. J Biomed Mater Res 1999, 45(3):268-275.
    • (1999) J Biomed Mater Res , vol.45 , Issue.3 , pp. 268-275
    • Godbey, W.T.1    Wu, K.K.2    Mikos, A.G.3
  • 30
    • 0346634895 scopus 로고    scopus 로고
    • In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis
    • Fischer D., Li Y., Ahlemeyer B., Krieglstein J., Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials 2003, 24(7):1121-1131.
    • (2003) Biomaterials , vol.24 , Issue.7 , pp. 1121-1131
    • Fischer, D.1    Li, Y.2    Ahlemeyer, B.3    Krieglstein, J.4    Kissel, T.5
  • 31
    • 77952953701 scopus 로고    scopus 로고
    • Hematopoietic effect of water-soluble polysaccharides from Angelica sinensison mice with acute blood loss
    • Liu P.J., Hsieh W.T., Huang S.H., Liao H.F., Chiang B.H. Hematopoietic effect of water-soluble polysaccharides from Angelica sinensison mice with acute blood loss. Exp Hematol 2010, 38(6):437-445.
    • (2010) Exp Hematol , vol.38 , Issue.6 , pp. 437-445
    • Liu, P.J.1    Hsieh, W.T.2    Huang, S.H.3    Liao, H.F.4    Chiang, B.H.5
  • 32
    • 67349142372 scopus 로고    scopus 로고
    • Extraction, characterization of Angelica sinensis polysaccharides and modulatory effect of the polysaccharides and Tai Chi exercise on oxidative injury in middle-aged women subjects
    • Juan J., YingJie G., AiJun N. Extraction, characterization of Angelica sinensis polysaccharides and modulatory effect of the polysaccharides and Tai Chi exercise on oxidative injury in middle-aged women subjects. Carbohyd Polym 2009, 77(2):384-388.
    • (2009) Carbohyd Polym , vol.77 , Issue.2 , pp. 384-388
    • Juan, J.1    YingJie, G.2    AiJun, N.3
  • 33
    • 33749426610 scopus 로고    scopus 로고
    • Pectic polysaccharide isolated from Angelica gigas Nakai inhibits melanoma cell metastasis and growth by directly preventing cell adhesion and activating host immune functions
    • Han S.B., Lee C.W., Kang M.R., Yoon Y.D., Kang J.S., Lee K.H., et al. Pectic polysaccharide isolated from Angelica gigas Nakai inhibits melanoma cell metastasis and growth by directly preventing cell adhesion and activating host immune functions. Cancer Lett 2006, 243(2):264-273.
    • (2006) Cancer Lett , vol.243 , Issue.2 , pp. 264-273
    • Han, S.B.1    Lee, C.W.2    Kang, M.R.3    Yoon, Y.D.4    Kang, J.S.5    Lee, K.H.6
  • 34
    • 33750163200 scopus 로고    scopus 로고
    • Immunomodulatory activity of polysaccharide isolated from Angelica sinensis
    • Yang T., Jia M., Meng J., Wu H., Mei Q. Immunomodulatory activity of polysaccharide isolated from Angelica sinensis. Int J Biol Macromol 2006, 39(4):179-184.
    • (2006) Int J Biol Macromol , vol.39 , Issue.4 , pp. 179-184
    • Yang, T.1    Jia, M.2    Meng, J.3    Wu, H.4    Mei, Q.5
  • 35
    • 77949484717 scopus 로고    scopus 로고
    • Assessment and comparison of immunoregulatory activity of four hydrosoluble fractions of Angelica sinensis in vitro on the peritoneal macrophages in ICR mice
    • Chen Y., Duan J., Qian D., Guo J., Song B., Yang M. Assessment and comparison of immunoregulatory activity of four hydrosoluble fractions of Angelica sinensis in vitro on the peritoneal macrophages in ICR mice. Int Immunopharmacol 2010, 10(4):422-430.
    • (2010) Int Immunopharmacol , vol.10 , Issue.4 , pp. 422-430
    • Chen, Y.1    Duan, J.2    Qian, D.3    Guo, J.4    Song, B.5    Yang, M.6
  • 36
    • 71849119769 scopus 로고    scopus 로고
    • Characterizations and anti-tumor activities of three acidic polysaccharides from Angelica sinensis (Oliv.) Diels
    • Cao W., Li X.Q., Wang X., Li T., Chen X., Liu S.B., et al. Characterizations and anti-tumor activities of three acidic polysaccharides from Angelica sinensis (Oliv.) Diels. Int J Biol Macromol 2010, 46(1):115-122.
    • (2010) Int J Biol Macromol , vol.46 , Issue.1 , pp. 115-122
    • Cao, W.1    Li, X.Q.2    Wang, X.3    Li, T.4    Chen, X.5    Liu, S.B.6
  • 37
    • 77952072550 scopus 로고    scopus 로고
    • Microporation is a valuable transfection method for efficient gene delivery into human umbilical cord blood-derived mesenchymal stem cells
    • Lim J., Park S., Jeong C., Oh J., Kim S., Ryu C., et al. Microporation is a valuable transfection method for efficient gene delivery into human umbilical cord blood-derived mesenchymal stem cells. BMC Biotechnol 2010, 10(1):38.
    • (2010) BMC Biotechnol , vol.10 , Issue.1 , pp. 38
    • Lim, J.1    Park, S.2    Jeong, C.3    Oh, J.4    Kim, S.5    Ryu, C.6
  • 38
    • 40649115896 scopus 로고    scopus 로고
    • A cartilage ECM-derived 3-D porous acellular matrix scaffold for in vivo cartilage tissue engineering with PKH26-labeled chondrogenic bone marrow-derived mesenchymal stem cells
    • Yang Q., Peng J., Guo Q., Huang J., Zhang L., Yao J., et al. A cartilage ECM-derived 3-D porous acellular matrix scaffold for in vivo cartilage tissue engineering with PKH26-labeled chondrogenic bone marrow-derived mesenchymal stem cells. Biomaterials 2008, 29(15):2378-2387.
    • (2008) Biomaterials , vol.29 , Issue.15 , pp. 2378-2387
    • Yang, Q.1    Peng, J.2    Guo, Q.3    Huang, J.4    Zhang, L.5    Yao, J.6
  • 39
    • 36949005434 scopus 로고    scopus 로고
    • Delivery of plasmid IGF-1 to chondrocytes via cationized gelatin nanoparticles
    • Xu X., Capito R.M., Spector M. Delivery of plasmid IGF-1 to chondrocytes via cationized gelatin nanoparticles. J Biomed Mater Res A 2008, 84(1):73-83.
    • (2008) J Biomed Mater Res A , vol.84 , Issue.1 , pp. 73-83
    • Xu, X.1    Capito, R.M.2    Spector, M.3
  • 40
    • 31544461289 scopus 로고    scopus 로고
    • PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo
    • Wong K., Sun G., Zhang X., Dai H., Liu Y., He C., et al. PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo. Bioconjug Chem 2006, 17(1):152-158.
    • (2006) Bioconjug Chem , vol.17 , Issue.1 , pp. 152-158
    • Wong, K.1    Sun, G.2    Zhang, X.3    Dai, H.4    Liu, Y.5    He, C.6
  • 41
    • 0029044182 scopus 로고
    • Preparation and characteristics of magnetite-labelled antibody with the use of poly (ethylene glycol) derivatives
    • Suzuki M., Shinkai M., Kamihira M., Kobayashi T. Preparation and characteristics of magnetite-labelled antibody with the use of poly (ethylene glycol) derivatives. Biotechnol Appl Biochem 1995, 21(3):335-345.
    • (1995) Biotechnol Appl Biochem , vol.21 , Issue.3 , pp. 335-345
    • Suzuki, M.1    Shinkai, M.2    Kamihira, M.3    Kobayashi, T.4
  • 42
    • 0034005095 scopus 로고    scopus 로고
    • Chitosan, a drug carrier for the 21st century: a review
    • Paul W., Sharma C. Chitosan, a drug carrier for the 21st century: a review. STP Pharma Sci 2000, 10(1):5-22.
    • (2000) STP Pharma Sci , vol.10 , Issue.1 , pp. 5-22
    • Paul, W.1    Sharma, C.2
  • 43
    • 23444441931 scopus 로고    scopus 로고
    • Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery
    • Gan Q., Wang T., Cochrane C., McCarron P. Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery. Colloids Surf B Biointerfaces 2005, 44(2):65-73.
    • (2005) Colloids Surf B Biointerfaces , vol.44 , Issue.2 , pp. 65-73
    • Gan, Q.1    Wang, T.2    Cochrane, C.3    McCarron, P.4
  • 44
    • 0037026269 scopus 로고    scopus 로고
    • Size-dependency of nanoparticle-mediated gene transfection: studies with fractionated nanoparticles
    • Prabha S., Zhou W.Z., Panyam J., Labhasetwar V. Size-dependency of nanoparticle-mediated gene transfection: studies with fractionated nanoparticles. Int J Pharm 2002, 244(1):105-115.
    • (2002) Int J Pharm , vol.244 , Issue.1 , pp. 105-115
    • Prabha, S.1    Zhou, W.Z.2    Panyam, J.3    Labhasetwar, V.4
  • 45
    • 39749188069 scopus 로고    scopus 로고
    • Plasmid size influences chitosan nanoparticle mediated gene transfer to chondrocytes
    • Xu X., Capito R.M., Spector M. Plasmid size influences chitosan nanoparticle mediated gene transfer to chondrocytes. J Biomed Mater Res A 2008, 84A(4):1038-1048.
    • (2008) J Biomed Mater Res A , vol.84 A , Issue.4 , pp. 1038-1048
    • Xu, X.1    Capito, R.M.2    Spector, M.3
  • 46
    • 0032484162 scopus 로고    scopus 로고
    • Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery
    • MacLaughlin F.C., Mumper R.J., Wang J., Tagliaferri J.M., Gill I., Hinchcliffe M., et al. Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery. J Control Release 1998, 56(1):259-272.
    • (1998) J Control Release , vol.56 , Issue.1 , pp. 259-272
    • MacLaughlin, F.C.1    Mumper, R.J.2    Wang, J.3    Tagliaferri, J.M.4    Gill, I.5    Hinchcliffe, M.6
  • 47
    • 28444448090 scopus 로고    scopus 로고
    • Relationships between chemical composition, physical properties and transfection efficiency of polysaccharide-spermine conjugates
    • Eliyahu H., Siani S., Azzam T., Domb A.J., Barenholz Y. Relationships between chemical composition, physical properties and transfection efficiency of polysaccharide-spermine conjugates. Biomaterials 2006, 27(8):1646-1655.
    • (2006) Biomaterials , vol.27 , Issue.8 , pp. 1646-1655
    • Eliyahu, H.1    Siani, S.2    Azzam, T.3    Domb, A.J.4    Barenholz, Y.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.