-
1
-
-
79957487176
-
Subclinical regional left ventricular dysfunction in obese patients with and without hypertension or hypertrophy
-
Silver Spring
-
Santos JL, Salemi VM, Picard MH, Mady C, Coelho OR 2011 Subclinical regional left ventricular dysfunction in obese patients with and without hypertension or hypertrophy. Obesity (Silver Spring) 19:1296-1303
-
(2011)
Obesity
, vol.19
, pp. 1296-1303
-
-
Santos, J.L.1
Salemi, V.M.2
Picard, M.H.3
Mady, C.4
Coelho, O.R.5
-
2
-
-
52649174353
-
Early cardiac abnormalities in obese children: Importance of obesity per se versus associated cardiovascular risk factors
-
Van Putte-Katier N, Rooman RP, Haas L, Verhulst SL, Desager KN, Ramet J, Suys BE 2008 Early cardiac abnormalities in obese children: importance of obesity per se versus associated cardiovascular risk factors. Pediatr Res 64:205-209
-
(2008)
Pediatr Res
, vol.64
, pp. 205-209
-
-
Van Putte-Katier, N.1
Rooman, R.P.2
Haas, L.3
Verhulst, S.L.4
Desager, K.N.5
Ramet, J.6
Suys, B.E.7
-
3
-
-
20244378531
-
Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: Restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor
-
DOI 10.1161/01.CIR.0000162472.52990.36
-
Yoon YS, Uchida S, Masuo O, Cejna M, Park JS, Gwon HC, Kirchmair R, Bahlman F, Walter D, Curry C, Hanley A, Isner JM, Losordo DW 2005 Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor. Circulation 111:2073-2085 (Pubitemid 40577902)
-
(2005)
Circulation
, vol.111
, Issue.16
, pp. 2073-2085
-
-
Yoon, Y.-S.1
Uchida, S.2
Masuo, O.3
Cejna, M.4
Park, J.-S.5
Gwon, H.-C.6
Kirchmair, R.7
Bahlman, F.8
Walter, D.9
Curry, C.10
Hanley, A.11
Isner, J.M.12
Losordo, D.W.13
-
4
-
-
0026081237
-
The epidemiology of impaired glucose tolerance and hypertension
-
Kannel WB, Wilson PW, Zhang TJ 1991 The epidemiology of impaired glucose tolerance and hypertension. Am Heart J 121:1268-1273
-
(1991)
Am Heart J
, vol.121
, pp. 1268-1273
-
-
Kannel, W.B.1
Wilson, P.W.2
Zhang, T.J.3
-
5
-
-
39749090528
-
Added impact of obesity and insulin resistance in nocturnal blood pressure elevation in children and adolescents
-
DOI 10.1161/HYPERTENSIONAHA.107.099234
-
Lurbe E, Torro I, Aguilar F, Alvarez J, Alcon J, Pascual JM, Redon J 2008 Added impact of obesity and insulin resistance in nocturnal blood pressure elevation in children and adolescents. Hypertension 51:635-641 (Pubitemid 351301514)
-
(2008)
Hypertension
, vol.51
, Issue.3
, pp. 635-641
-
-
Lurbe, E.1
Torro, I.2
Aguilar, F.3
Alvarez, J.4
Alcon, J.5
Pascual, J.M.6
Redon, J.7
-
6
-
-
33748455218
-
Non-dippers are associated with adverse cardiac remodeling and dysfunction (R1)
-
DOI 10.1016/j.ijcard.2005.08.038, PII S016752730501171X
-
Seo HS, Kang TS, Park S, Choi EY, Ko YG, Choi D, Ha J, Rim SJ, Chung N 2006 Non-dippers are associated with adverse cardiac remodeling and dysfunction (R1). Int J Cardiol 112:171-177 (Pubitemid 44353794)
-
(2006)
International Journal of Cardiology
, vol.112
, Issue.2
, pp. 171-177
-
-
Seo, H.-S.1
Soo, K.T.2
Park, S.3
Young, C.E.4
Ko, Y.-G.5
Choi, D.6
Ha, J.7
Rim, S.-J.8
Chung, N.9
-
7
-
-
84870821381
-
To dip or not to dip? The unique relationship between different blood pressure patterns and cardiac function and structure
-
8 September 10.1038/jhh.2011.83
-
Ivanovic BA, Tadic MV, Celic VP 8 September 2011 To dip or not to dip? The unique relationship between different blood pressure patterns and cardiac function and structure. J Hum Hypertens 10.1038/jhh.2011.83
-
(2011)
J Hum Hypertens
-
-
Ivanovic, B.A.1
Tadic, M.V.2
Celic, V.P.3
-
8
-
-
83455229494
-
Re-evaluating lipotoxic triggers in skeletal muscle: Relating intramyocellular lipid metabolism to insulin sensitivity
-
Bosma M, Kersten S, Hesselink MK, Schrauwen P 2012 Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity. Prog Lipid Res 51:36-49
-
(2012)
Prog Lipid Res
, vol.51
, pp. 36-49
-
-
Bosma, M.1
Kersten, S.2
Hesselink, M.K.3
Schrauwen, P.4
-
9
-
-
60149088480
-
From chronic overnutrition to insulin resistance: The role of fat-storing capacity and inflammation
-
Lionetti L, Mollica MP, Lombardi A, Cavaliere G, Gifuni G, Barletta A 2009 From chronic overnutrition to insulin resistance: the role of fat-storing capacity and inflammation. Nutr Metab Cardiovasc Dis 19:146-152
-
(2009)
Nutr Metab Cardiovasc Dis
, vol.19
, pp. 146-152
-
-
Lionetti, L.1
Mollica, M.P.2
Lombardi, A.3
Cavaliere, G.4
Gifuni, G.5
Barletta, A.6
-
10
-
-
79551495757
-
Role of cardiac steatosis and lipotoxicity in obesity cardiomyopathy
-
Zhang Y, Ren J 2011 Role of cardiac steatosis and lipotoxicity in obesity cardiomyopathy. Hypertension 57:148-150
-
(2011)
Hypertension
, vol.57
, pp. 148-150
-
-
Zhang, Y.1
Ren, J.2
-
11
-
-
34547961920
-
Cardiac energy metabolism in obesity
-
DOI 10.1161/CIRCRESAHA.107.150417, PII 0000301220070817000006
-
Lopaschuk GD, Folmes CD, Stanley WC 2007 Cardiac energy metabolism in obesity. Circ Res 101:335-347 (Pubitemid 47267702)
-
(2007)
Circulation Research
, vol.101
, Issue.4
, pp. 335-347
-
-
Lopaschuk, G.D.1
Folmes, C.D.L.2
Stanley, W.C.3
-
12
-
-
0035798670
-
Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats
-
Luiken JJ, Arumugam Y, Dyck DJ, Bell RC, Pelsers MM, Turcotte LP, Tandon NN, Glatz JF, Bonen A 2001 Increased rates of fatty acid uptake and plasmalemmal fatty acid transporters in obese Zucker rats. J Biol Chem 276:40567-40573
-
(2001)
J Biol Chem
, vol.276
, pp. 40567-40573
-
-
Luiken, J.J.1
Arumugam, Y.2
Dyck, D.J.3
Bell, R.C.4
Pelsers, M.M.5
Turcotte, L.P.6
Tandon, N.N.7
Glatz, J.F.8
Bonen, A.9
-
14
-
-
55949119360
-
Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus
-
Rijzewijk LJ, van der Meer RW, Smit JW, Diamant M, Bax JJ, Hammer S, Romijn JA, de Roos A, Lamb HJ 2008 Myocardial steatosis is an independent predictor of diastolic dysfunction in type 2 diabetes mellitus. J Am Coll Cardiol 52:1793-1799
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 1793-1799
-
-
Rijzewijk, L.J.1
Van Der Meer, R.W.2
Smit, J.W.3
Diamant, M.4
Bax, J.J.5
Hammer, S.6
Romijn, J.A.7
De Roos, A.8
Lamb, H.J.9
-
15
-
-
0042315364
-
Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
-
DOI 10.1210/en.2003-0242
-
Christoffersen C, Bollano E, Lindegaard ML, Bartels ED, Goetze JP, Andersen CB, Nielsen LB 2003 Cardiac lipid accumulation associated with diastolic dysfunction in obese mice. Endocrinology 144:3483-3490 (Pubitemid 36904426)
-
(2003)
Endocrinology
, vol.144
, Issue.8
, pp. 3483-3490
-
-
Christoffersen, C.1
Bollano, E.2
Lindegaard, M.L.S.3
Bartels, E.D.4
Goetze, J.P.5
Andersen, C.B.6
Nielsen, L.B.7
-
17
-
-
0020563445
-
Lessons from studies with genetic forms of diabetes in the mouse
-
Coleman DL 1983 Lessons from studies with genetic forms of diabetes in the mouse. Metabolism 32:162-164 (Pubitemid 13077669)
-
(1983)
Metabolism: Clinical and Experimental
, vol.32
, Issue.7 SUPPL. 1
, pp. 162-164
-
-
Coleman, D.L.1
-
18
-
-
59849125655
-
Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunction
-
da Costa Goncalves AC, Tank J, Diedrich A, Hilzendeger A, Plehm R, Bader M, Luft FC, Jordan J, Gross V 2009 Diabetic hypertensive leptin receptor-deficient db/db mice develop cardioregulatory autonomic dysfunction. Hypertension 53:387-392
-
(2009)
Hypertension
, vol.53
, pp. 387-392
-
-
Da Costa Goncalves, A.C.1
Tank, J.2
Diedrich, A.3
Hilzendeger, A.4
Plehm, R.5
Bader, M.6
Luft, F.C.7
Jordan, J.8
Gross, V.9
-
19
-
-
57049155556
-
Hypertension and disrupted blood pressure circadian rhythm in type 2 diabetic db/db mice
-
Su W, Guo Z, Randall DC, Cassis L, Brown DR, Gong MC 2008 Hypertension and disrupted blood pressure circadian rhythm in type 2 diabetic db/db mice. Am J Physiol Heart Circ Physiol 295:H1634-H1641
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Su, W.1
Guo, Z.2
Randall, D.C.3
Cassis, L.4
Brown, D.R.5
Gong, M.C.6
-
20
-
-
77958026411
-
Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress
-
Zhang H, Morgan B, Potter BJ, Ma L, Dellsperger KC, Ungvari Z, Zhang C 2010 Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress. Am J Physiol Heart Circ Physiol 299:H985-H994
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.299
-
-
Zhang, H.1
Morgan, B.2
Potter, B.J.3
Ma, L.4
Dellsperger, K.C.5
Ungvari, Z.6
Zhang, C.7
-
21
-
-
77950466818
-
Nebivolol improves diastolic dysfunction and myocardial tissue remodeling through reductions in oxidative stress in the Zucker Obese rat
-
Zhou X, Ma L, Habibi J, Whaley-Connell A, Hayden MR, Tilmon RD, Brown AN, Kim JA, Demarco VG, Sowers JR 2009 Nebivolol improves diastolic dysfunction and myocardial tissue remodeling through reductions in oxidative stress in the Zucker Obese rat. Hypertension 55:880-888
-
(2009)
Hypertension
, vol.55
, pp. 880-888
-
-
Zhou, X.1
Ma, L.2
Habibi, J.3
Whaley-Connell, A.4
Hayden, M.R.5
Tilmon, R.D.6
Brown, A.N.7
Kim, J.A.8
Demarco, V.G.9
Sowers, J.R.10
-
22
-
-
80053235409
-
Sex differences in baroreflex sensitivity, heart rate variability, and end organ damage in the TGR(mRen2)27 rat
-
Johnson MS, DeMarco VG, Heesch CM, Whaley-Connell AT, Schneider RI, Rehmer NT, Tilmon RD, Ferrario CM, Sowers JR 2011 Sex differences in baroreflex sensitivity, heart rate variability, and end organ damage in the TGR(mRen2)27 rat. Am J Physiol Heart Circ Physiol 301:H1540-H1550
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Johnson, M.S.1
DeMarco, V.G.2
Heesch, C.M.3
Whaley-Connell, A.T.4
Schneider, R.I.5
Rehmer, N.T.6
Tilmon, R.D.7
Ferrario, C.M.8
Sowers, J.R.9
-
23
-
-
84859750480
-
Overweight female rats selectively bred for low aerobic capacity exhibit increased myocardial fibrosis and diastolic dysfunction
-
DeMarco VG, Johnson MS, Ma L, Pulakat L, Mugerfeld I, Hayden MR, Garro M, Knight W, Britton SL, Koch LG, Sowers JR 2012 Overweight female rats selectively bred for low aerobic capacity exhibit increased myocardial fibrosis and diastolic dysfunction. Am J Physiol Heart Circ Physiol 302:H1667-H1682
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
-
-
DeMarco, V.G.1
Johnson, M.S.2
Ma, L.3
Pulakat, L.4
Mugerfeld, I.5
Hayden, M.R.6
Garro, M.7
Knight, W.8
Britton, S.L.9
Koch, L.G.10
Sowers, J.R.11
-
24
-
-
34547123088
-
Angiotensin II-mediated oxidative stress promotes myocardial tissue remodeling in the transgenic (mRen2) 27 Ren2 rat
-
DOI 10.1152/ajpendo.00632.2006
-
Whaley-Connell A, Govindarajan G, Habibi J, Hayden MR, Cooper SA, Wei Y, Ma L, Qazi M, Link D, Karuparthi PR, Stump C, Ferrario CM, Sowers JR 2007 Angiotensin-II mediated oxidative stress promotes myocardial tissue remodeling in the transgenic TG (mRen2) 27 Ren2 rat. Am J Physiol Endocrinol Metab 293:E355-E363 (Pubitemid 47105951)
-
(2007)
American Journal of Physiology - Endocrinology and Metabolism
, vol.293
, Issue.1
-
-
Whaley-Connell, A.1
Govindarajan, G.2
Habibi, J.3
Hayden, M.R.4
Cooper, S.A.5
Wei, Y.6
Ma, L.7
Qazi, M.8
Link, D.9
Karuparthi, P.R.10
Stump, C.11
Ferrario, C.12
Sowers, J.R.13
-
25
-
-
49249118303
-
Oxidative Stress Contributes to Pulmonary Hypertension in the Transgenic (mRen2) 27 Ren2 Rat
-
DeMarco VG, Habibi J, Whaley-Connell AT, Schneider RI, Heller RL, Bosanquet JP, Hayden MR, Delcour K, Cooper SA, Andresen BT, Sowers JR, Dellsperger KC 2008 Oxidative Stress Contributes to Pulmonary Hypertension in the Transgenic (mRen2) 27 Ren2 Rat. Am J Physiol Heart Circ Physiol 294:H2659-H2668
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
DeMarco, V.G.1
Habibi, J.2
Whaley-Connell, A.T.3
Schneider, R.I.4
Heller, R.L.5
Bosanquet, J.P.6
Hayden, M.R.7
Delcour, K.8
Cooper, S.A.9
Andresen, B.T.10
Sowers, J.R.11
Dellsperger, K.C.12
-
26
-
-
33845261493
-
A rapid method of total lipid extraction and purification
-
Bligh EG, Dyer WJ 1959 A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37:911-917
-
(1959)
Can J Biochem Physiol
, vol.37
, pp. 911-917
-
-
Bligh, E.G.1
Dyer, W.J.2
-
27
-
-
80051544556
-
Analysis of cholesteryl esters and diacylglycerols using lithiated adducts and electrospray ionization-tandem mass spectrometry
-
Bowden JA, Albert CJ, Barnaby OS, Ford DA 2011 Analysis of cholesteryl esters and diacylglycerols using lithiated adducts and electrospray ionization-tandem mass spectrometry. Anal Biochem 417:202-210
-
(2011)
Anal Biochem
, vol.417
, pp. 202-210
-
-
Bowden, J.A.1
Albert, C.J.2
Barnaby, O.S.3
Ford, D.A.4
-
28
-
-
18344393519
-
Shotgun lipidomics: Electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples
-
DOI 10.1002/mas.20023
-
Han X, Gross RW 2005 Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples. Mass Spectrom Rev 24:367-412 (Pubitemid 40665798)
-
(2005)
Mass Spectrometry Reviews
, vol.24
, Issue.3
, pp. 367-412
-
-
Han, X.1
Gross, R.W.2
-
29
-
-
0035425057
-
Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry
-
DOI 10.1006/abio.2001.5178
-
Han X, Gross RW 2001 Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry. Anal Biochem 295:88-100 (Pubitemid 32721744)
-
(2001)
Analytical Biochemistry
, vol.295
, Issue.1
, pp. 88-100
-
-
Han, X.1
Gross, R.W.2
-
30
-
-
78650481257
-
Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation
-
Zhang L, Ussher JR, Oka T, Cadete VJ, Wagg C, Lopaschuk GD 2011 Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation. Cardiovasc Res 89:148-156
-
(2011)
Cardiovasc Res
, vol.89
, pp. 148-156
-
-
Zhang, L.1
Ussher, J.R.2
Oka, T.3
Cadete, V.J.4
Wagg, C.5
Lopaschuk, G.D.6
-
31
-
-
0036353834
-
Echocardiographic assessment of cardiac function in diabetic db/db and transgenic db/db-hGLUT4 mice
-
Semeniuk LM, Kryski AJ, Severson DL 2002 Echocardiographic assessment of cardiac function in diabetic db/db and transgenic db/db-hGLUT4 mice. Am J Physiol Heart Circ Physiol 283:H976-H982
-
(2002)
Am J Physiol Heart Circ Physiol
, vol.283
-
-
Semeniuk, L.M.1
Kryski, A.J.2
Severson, D.L.3
-
32
-
-
33751217697
-
Type II diabetic mice exhibit contractile dysfunction but maintain cardiac output by favourable loading conditions
-
DOI 10.1016/j.ejheart.2006.03.001, PII S1388984206000675
-
Vanden Bergh A, Flameng W, Herijgers P 2006 Type II diabetic mice exhibit contractile dysfunction but maintain cardiac output by favourable loading conditions. Eur J Heart Fail 8:777-783 (Pubitemid 44781425)
-
(2006)
European Journal of Heart Failure
, vol.8
, Issue.8
, pp. 777-783
-
-
Van Den, B.A.1
Flameng, W.2
Herijgers, P.3
-
33
-
-
63849319211
-
The effect of nondipping blood pressure patterns on cardiac structural changes and left ventricular diastolic functions in normotensives
-
Soylu A, Duzenli MA, Yazici M, Ozdemir K, Tokac M, Gok H 2009 The effect of nondipping blood pressure patterns on cardiac structural changes and left ventricular diastolic functions in normotensives. Echocardiography 26:378-387
-
(2009)
Echocardiography
, vol.26
, pp. 378-387
-
-
Soylu, A.1
Duzenli, M.A.2
Yazici, M.3
Ozdemir, K.4
Tokac, M.5
Gok, H.6
-
34
-
-
65649109348
-
Cardiovascular and autonomic phenotype of db/db diabetic mice
-
Senador D, Kanakamedala K, Irigoyen MC, Morris M, Elased KM 2009 Cardiovascular and autonomic phenotype of db/db diabetic mice. Exp Physiol 94:648-658
-
(2009)
Exp Physiol
, vol.94
, pp. 648-658
-
-
Senador, D.1
Kanakamedala, K.2
Irigoyen, M.C.3
Morris, M.4
Elased, K.M.5
-
35
-
-
77953440109
-
Diabetic cardiomyopathy, causes and effects
-
Boudina S, Abel ED 2010 Diabetic cardiomyopathy, causes and effects. Rev Endocr Metab Disord 11:31-39
-
(2010)
Rev Endocr Metab Disord
, vol.11
, pp. 31-39
-
-
Boudina, S.1
Abel, E.D.2
-
36
-
-
78149409465
-
Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease
-
Ren J, Pulakat L, Whaley-Connell A, Sowers JR 2010 Mitochondrial biogenesis in the metabolic syndrome and cardiovascular disease. J Mol Med 88:993-1001
-
(2010)
J Mol Med
, vol.88
, pp. 993-1001
-
-
Ren, J.1
Pulakat, L.2
Whaley-Connell, A.3
Sowers, J.R.4
-
37
-
-
77956572071
-
Mitochondria in the diabetic heart
-
Bugger H, Abel ED 2010 Mitochondria in the diabetic heart. Cardiovasc Res 88:229-240
-
(2010)
Cardiovasc Res
, vol.88
, pp. 229-240
-
-
Bugger, H.1
Abel, E.D.2
-
38
-
-
27444441492
-
Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity
-
DOI 10.1161/CIRCULATIONAHA.105.554360
-
Boudina S, Sena S, O'Neill BT, Tathireddy P, Young ME, Abel ED 2005 Reduced mitochondrial oxidative capacity and increased mitochondrial uncoupling impair myocardial energetics in obesity. Circulation 112:2686-2695 (Pubitemid 41532606)
-
(2005)
Circulation
, vol.112
, Issue.17
, pp. 2686-2695
-
-
Boudina, S.1
Sena, S.2
O'Neill, B.T.3
Tathireddy, P.4
Young, M.E.5
Abel, E.D.6
-
39
-
-
34548848059
-
Mitochondrial energetics in the heart in obesity-related diabetes: Direct evidence for increased uncoupled respiration and activation of uncoupling proteins
-
DOI 10.2337/db07-0481
-
Boudina S, Sena S, Theobald H, Sheng X, Wright JJ, Hu XX, Aziz S, Johnson JI, Bugger H, Zaha VG, Abel ED 2007 Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins. Diabetes 56:2457-2466 (Pubitemid 47523253)
-
(2007)
Diabetes
, vol.56
, Issue.10
, pp. 2457-2466
-
-
Boudina, S.1
Sena, S.2
Theobald, H.3
Sheng, X.4
Wright, J.J.5
Xia, X.H.6
Aziz, S.7
Johnson, J.I.8
Bugger, H.9
Zaha, V.G.10
Abel, E.D.11
-
40
-
-
27844457564
-
Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity
-
DOI 10.1210/en.2005-0938
-
Buchanan J, Mazumder PK, Hu P, Chakrabarti G, Roberts MW, Yun UJ, Cooksey RC, Litwin SE, Abel ED 2005 Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity. Endocrinology 146:5341-5349 (Pubitemid 41653047)
-
(2005)
Endocrinology
, vol.146
, Issue.12
, pp. 5341-5349
-
-
Buchanan, J.1
Mazumder, P.K.2
Hu, P.3
Chakrabarti, G.4
Roberts, M.W.5
Ui, J.Y.6
Cooksey, R.C.7
Litwin, S.E.8
Abel, E.D.9
-
41
-
-
0037315085
-
Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice
-
DOI 10.2337/diabetes.52.2.434
-
Aasum E, Hafstad AD, Severson DL, Larsen TS 2003 Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice. Diabetes 52:434-441 (Pubitemid 36173200)
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 434-441
-
-
Aasum, E.1
Hafstad, A.D.2
Severson, D.L.3
Larsen, T.S.4
-
42
-
-
13444268937
-
Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy
-
DOI 10.1161/01.RES.0000154079.20681.B9
-
Chiu HC, Kovacs A, Blanton RM, Han X, Courtois M, Weinheimer CJ, Yamada KA, Brunet S, Xu H, Nerbonne JM, Welch MJ, Fettig NM, Sharp TL, Sambandam N, Olson KM, Ory DS, Schaffer JE 2005 Transgenic expression of fatty acid transport protein 1 in the heart causes lipotoxic cardiomyopathy. Circ Res 96:225-233 (Pubitemid 40209370)
-
(2005)
Circulation Research
, vol.96
, Issue.2
, pp. 225-233
-
-
Chiu, H.-C.1
Kovacs, A.2
Blanton, R.M.3
Han, X.4
Courtois, M.5
Weinheimer, C.J.6
Yamada, K.A.7
Brunei, S.8
Xu, H.9
Nerbonne, J.M.10
Welch, M.J.11
Fettig, N.M.12
Sharp, T.L.13
Sambandam, N.14
Olson, K.M.15
Ory, D.S.16
Schaffer, J.E.17
-
43
-
-
0035061419
-
A novel mouse model of lipotoxic cardiomyopathy
-
Chiu HC, Kovacs A, Ford DA, Hsu FF, Garcia R, Herrero P, Saffitz JE, Schaffer JE 2001 A novel mouse model of lipotoxic cardiomyopathy. J Clin Invest 107:813-822 (Pubitemid 32274034)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.7
, pp. 813-822
-
-
Chiu, H.-C.1
Kovacs, A.2
Ford, D.A.3
Hsu, F.-F.4
Garcia, R.5
Herrero, P.6
Saffitz, J.E.7
Schaffer, J.E.8
-
44
-
-
79953329970
-
Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans
-
Rhee EP, Cheng S, Larson MG, Walford GA, Lewis GD, McCabe E, Yang E, Farrell L, Fox CS, O'Donnell CJ, Carr SA, Vasan RS, Florez JC, Clish CB, Wang TJ, Gerszten RE 2011 Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans. J Clin Invest 121:1402-1411
-
(2011)
J Clin Invest
, vol.121
, pp. 1402-1411
-
-
Rhee, E.P.1
Cheng, S.2
Larson, M.G.3
Walford, G.A.4
Lewis, G.D.5
McCabe, E.6
Yang, E.7
Farrell, L.8
Fox, C.S.9
O'Donnell, C.J.10
Carr, S.A.11
Vasan, R.S.12
Florez, J.C.13
Clish, C.B.14
Wang, T.J.15
Gerszten, R.E.16
-
45
-
-
0037117651
-
Adaptation and maladaptation of the heart in diabetes: Part II: Potential mechanisms
-
DOI 10.1161/01.CIR.0000012467.61045.87
-
Young ME, McNulty P, Taegtmeyer H 2002 Adaptation and maladaptation of the heart in diabetes: part II: potential mechanisms. Circulation 105:1861-1870 (Pubitemid 34408899)
-
(2002)
Circulation
, vol.105
, Issue.15
, pp. 1861-1870
-
-
Young, M.E.1
McNulty, P.2
Taegtmeyer, H.3
-
46
-
-
0032917447
-
2+-sensitive isoforms in the failing human heart
-
Bowling N, Walsh RA, Song G, Estridge T, Sandusky GE, Fouts RL, Mintze K, Pickard T, Roden R, Bristow MR, Sabbah HN, Mizrahi JL, Gromo G, King GL, Vlahos CJ 1999 Increased protein kinase C activity and expression of Ca2+-sensitive isoforms in the failing human heart. Circulation 99:384-391 (Pubitemid 29051264)
-
(1999)
Circulation
, vol.99
, Issue.3
, pp. 384-391
-
-
Bowling, N.1
Walsh, R.A.2
Song, G.3
Estridge, T.4
Sandusky, G.E.5
Fouts, R.L.6
Mintze, K.7
Pickard, T.8
Roden, R.9
Bristow, M.R.10
Sabbah, H.N.11
Mizrahi, J.L.12
Gromo, G.13
King, G.L.14
Vlahos, C.J.15
-
47
-
-
0344011683
-
Protein Kinase Cα Negatively Regulates Systolic and Diastolic Function in Pathological Hypertrophy
-
DOI 10.1161/01.RES.0000105087.79373.17
-
Hahn HS, Marreez Y, Odley A, Sterbling A, Yussman MG, Hilty KC, Bodi I, Liggett SB, Schwartz A, Dorn 2nd GW 2003 Protein kinase Cα negatively regulates systolic and diastolic function in pathological hypertrophy. Circ Res 93:1111-1119 (Pubitemid 37485043)
-
(2003)
Circulation Research
, vol.93
, Issue.11
, pp. 1111-1119
-
-
Hahn, H.S.1
Marreez, Y.2
Odley, A.3
Sterbling, A.4
Yussman, M.G.5
Hilty, K.C.6
Bodi, I.7
Liggett, S.B.8
Schwartz, A.9
Dorn II, G.W.10
-
48
-
-
80052450388
-
A newtwist in the function of the cardiac lipid droplet
-
Abel ED 2011 A newtwist in the function of the cardiac lipid droplet. Nat Med 17:1045-1046
-
(2011)
Nat Med
, vol.17
, pp. 1045-1046
-
-
Abel, E.D.1
-
49
-
-
33645093211
-
Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage
-
DOI 10.1152/ajpendo.00139.2005
-
O'Donnell JM, Zampino M, Alpert NM, Fasano MJ, Geenen DL, Lewandowski ED 2006 Accelerated triacylglycerol turnover kinetics in hearts of diabetic rats include evidence for compartmented lipid storage. Am J Physiol Endocrinol Metab 290:E448-E455 (Pubitemid 43671690)
-
(2006)
American Journal of Physiology - Endocrinology and Metabolism
, vol.290
, Issue.3
-
-
O'Donnell, J.M.1
Zampino, M.2
Alpert, N.M.3
Fasano, M.J.4
Geenen, D.L.5
Lewandowski, E.D.6
-
50
-
-
77952688942
-
Western diet changes cardiac acyl-CoA composition in obese rats: A potential role for hepatic lipogenesis
-
Harmancey R, Wilson CR, Wright NR, Taegtmeyer H 2010 Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis. J Lipid Res 51:1380-1393
-
(2010)
J Lipid Res
, vol.51
, pp. 1380-1393
-
-
Harmancey, R.1
Wilson, C.R.2
Wright, N.R.3
Taegtmeyer, H.4
-
51
-
-
84882524309
-
Functional roles of lipids in membranes
-
Vance DE, Vance JE, eds. 5th ed. Amsterdam: Elsevier
-
Dowhan W, Bogdanov M, Mileykovskaya E 2008 Functional roles of lipids in membranes. In: Vance DE, Vance JE, eds. Biochemistry of lipids, lipoproteins and membranes. 5th ed. Amsterdam: Elsevier; 1-37
-
(2008)
Biochemistry of Lipids, Lipoproteins and Membranes
, pp. 1-37
-
-
Dowhan, W.1
Bogdanov, M.2
Mileykovskaya, E.3
-
52
-
-
54249093047
-
Ceramide is a cardiotoxin in lipotoxic cardiomyopathy
-
Park TS, Hu Y, Noh HL, Drosatos K, Okajima K, Buchanan J, Tuinei J, Homma S, Jiang XC, Abel ED, Goldberg IJ 2008 Ceramide is a cardiotoxin in lipotoxic cardiomyopathy. J Lipid Res 49:2101-2112
-
(2008)
J Lipid Res
, vol.49
, pp. 2101-2112
-
-
Park, T.S.1
Hu, Y.2
Noh, H.L.3
Drosatos, K.4
Okajima, K.5
Buchanan, J.6
Tuinei, J.7
Homma, S.8
Jiang, X.C.9
Abel, E.D.10
Goldberg, I.J.11
-
53
-
-
31644443192
-
Ceramides in insulin resistance and lipotoxicity
-
DOI 10.1016/j.plipres.2005.11.002, PII S0163782705000500
-
Summers SA 2006 Ceramides in insulin resistance and lipotoxicity. Prog Lipid Res 45:42-72 (Pubitemid 43170804)
-
(2006)
Progress in Lipid Research
, vol.45
, Issue.1
, pp. 42-72
-
-
Summers, S.A.1
-
54
-
-
33646544087
-
TNF-α contributes to endothelial dysfunction in ischemia/reperfusion injury
-
Zhang C, Xu X, Potter BJ, Wang W, Kuo L, Michael L, Bagby GJ, Chilian WM 2006 TNF-α contributes to endothelial dysfunction in ischemia/reperfusion injury. Arterioscler Thromb Vasc Biol 26:475-480
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 475-480
-
-
Zhang, C.1
Xu, X.2
Potter, B.J.3
Wang, W.4
Kuo, L.5
Michael, L.6
Bagby, G.J.7
Chilian, W.M.8
-
55
-
-
72249086779
-
Dietary soy protein reduces cardiac lipid accumulation and the ceramide concentration in high-fat diet-fed rats and ob/ob mice
-
Torre-Villalvazo I, Gonzalez F, Aguilar-Salinas CA, Tovar AR, Torres N 2009 Dietary soy protein reduces cardiac lipid accumulation and the ceramide concentration in high-fat diet-fed rats and ob/ob mice. J Nutr 139:2237-2243
-
(2009)
J Nutr
, vol.139
, pp. 2237-2243
-
-
Torre-Villalvazo, I.1
Gonzalez, F.2
Aguilar-Salinas, C.A.3
Tovar, A.R.4
Torres, N.5
-
56
-
-
34948910262
-
Cardiomyocyte expression of PPARγ leads to cardiac dysfunction in mice
-
DOI 10.1172/JCI30335
-
Son NH, Park TS, Yamashita H, Yokoyama M, Huggins LA, Okajima K, Homma S, Szabolcs MJ, Huang LS, Goldberg IJ 2007 Cardiomyocyte expression of PPARγ leads to cardiac dysfunction in mice. J Clin Invest 117:2791-2801 (Pubitemid 47529610)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.10
, pp. 2791-2801
-
-
Son, N.-H.1
Park, T.-S.2
Yamashita, H.3
Yokoyama, M.4
Huggins, L.A.5
Okajima, K.6
Homma, S.7
Szabolcs, M.J.8
Huang, L.-S.9
Goldberg, I.J.10
-
57
-
-
33750590489
-
Altered adipose and plasma sphingolipid metabolism in obesity: A potential mechanism for cardiovascular and metabolic risk
-
DOI 10.2337/db06-0330
-
Samad F, Hester KD, Yang G, Hannun YA, Bielawski J 2006 Altered adipose and plasma sphingolipid metabolism in obesity: a potential mechanism for cardiovascular and metabolic risk. Diabetes 55:2579-2587 (Pubitemid 44871159)
-
(2006)
Diabetes
, vol.55
, Issue.9
, pp. 2579-2587
-
-
Samad, F.1
Hester, K.D.2
Yang, G.3
Hannun, Y.A.4
Bielawski, J.5
-
58
-
-
84861541184
-
Cardiomyocyte specific deficiency of serine palmitoyltransferase subunit 2 reduces ceramide but leads to cardiac dysfunction
-
Lee SY, Kim JR, Hu Y, Khan R, Kim SJ, Bharadwaj KG, Davidson MM, Choi CS, Shin KO, Lee YM, Park WJ, Park IS, Jiang XC, Goldberg IJ, Park TS 2012 Cardiomyocyte specific deficiency of serine palmitoyltransferase subunit 2 reduces ceramide but leads to cardiac dysfunction. J Biol Chem 287:18429-18439
-
(2012)
J Biol Chem
, vol.287
, pp. 18429-18439
-
-
Lee, S.Y.1
Kim, J.R.2
Hu, Y.3
Khan, R.4
Kim, S.J.5
Bharadwaj, K.G.6
Davidson, M.M.7
Choi, C.S.8
Shin, K.O.9
Lee, Y.M.10
Park, W.J.11
Park, I.S.12
Jiang, X.C.13
Goldberg, I.J.14
Park, T.S.15
-
59
-
-
80053465191
-
Lipotoxicity and cardiac dysfunction in mammals and Drosophila
-
Birse RT, Bodmer R 2011 Lipotoxicity and cardiac dysfunction in mammals and Drosophila. Crit Rev Biochem Mol Biol 46:376-385
-
(2011)
Crit Rev Biochem Mol Biol
, vol.46
, pp. 376-385
-
-
Birse, R.T.1
Bodmer, R.2
-
60
-
-
79957605136
-
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
-
Fu S, Yang L, Li P, Hofmann O, Dicker L, Hide W, Lin X, Watkins SM, Ivanov AR, Hotamisligil GS 2011 Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature 473:528-531
-
(2011)
Nature
, vol.473
, pp. 528-531
-
-
Fu, S.1
Yang, L.2
Li, P.3
Hofmann, O.4
Dicker, L.5
Hide, W.6
Lin, X.7
Watkins, S.M.8
Ivanov, A.R.9
Hotamisligil, G.S.10
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