Relationship between bleeding time, aspirin and the PlA1/A2 polymorphism of platelet glycoprotein IIIa

British Journal of Haematology

Volumn 110, Issue 4, 2000, Pages 965-967

  Szczeklik, Andrzej ^a   Undas, Anetta ^a   Sanak, Marek ^a   Frolow, Marzena ^a   Wȩgrzyn, Wojciech ^a  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

Author keywords

Aspirin; Bleeding time; Platelet glycoprotein IIIa; Polymorphism; Thrombin generation

Indexed keywords

ACETYLSALICYLIC ACID; GLYCOPROTEIN IIIA; LEUCINE; PROLINE;

ADULT; ARTICLE; BLEEDING TIME; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; GENETIC POLYMORPHISM; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; THROMBOCYTE FUNCTION;

ADULT; ANTIGENS, HUMAN PLATELET; ASPIRIN; BLEEDING TIME; BLOOD PLATELETS; CHI-SQUARE DISTRIBUTION; HETEROZYGOTE; HUMANS; MALE; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; POLYMORPHISM, GENETIC; STATISTICS, NONPARAMETRIC;

EID: 0033761053     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02267.x     Document Type: Article

References (12)

1. PlA1/A2 polymorphism of platelet glycoprotein IIIa and risk of cardiovascular disease
2. Prevention of αIIbβ3 activation by non-steroidal antiinflammatory drugs
3. Increased platelet aggregability associated with platelet GPIIIa PlA2 polymorphism: The Framingham Offspring Study
4. The bleeding time response to aspirin. Identifying the hyperresponder
5. Increased binding of fibrinogen to glycoprotein IIIa proline 33 (HPA-1b, PlA2, Zwb) positive platelets in patients with cardiovascular disease
6. Two-year follow-up of aspirin responder and aspirin non-responder. A pilot study including 180 post-stroke patients
7. Effects of skin mast cells on bleeding time and coagulation activation at the site of platelet plug formation
8. Functional aspirin resistance in cardiac patients: Platelet aggregation compared to PFA-100
9. Induction of fibrinogen binding and platelet aggregation as a potential intrinsic property of various glycoprotein IIb/IIIa (αIIbβ3) inhibitors
10. Prolonged bleeding time, reduced aggregation, altered PAF-acether sensitivity and increased platelet mass are a trait of asthma and hay fever
11. Inhibition of thrombin generation by aspirin is blunted in hypercholesterolemia
12. Platelet glycoprotein IIIa polymorphism, aspirin, and thrombin generation