-
1
-
-
80053449113
-
DNA damage, signaling and repair: Protecting genomic integrity and reducing the risk of human disease
-
P. Zhou DNA damage, signaling and repair: Protecting genomic integrity and reducing the risk of human disease Chinese Sci. Bull. 56 2011 3119 3121
-
(2011)
Chinese Sci. Bull.
, vol.56
, pp. 3119-3121
-
-
Zhou, P.1
-
2
-
-
33751568508
-
The cellular control of DNA double-strand breaks
-
S.P. Scott, and T.K. Pandita The cellular control of DNA double-strand breaks J. Cell Biochem. 99 2006 1463 1475
-
(2006)
J. Cell Biochem.
, vol.99
, pp. 1463-1475
-
-
Scott, S.P.1
Pandita, T.K.2
-
3
-
-
84876274744
-
Histone Modifications and DNA Double-Strand Break Repair after Exposure to Ionizing Radiations
-
C.R. Hunt, D. Ramnarain, N. Horikoshi, P. Iyenger, R.K. Pandita, J.W. Shay, and T.K. Pandita Histone Modifications and DNA Double-Strand Break Repair after Exposure to Ionizing Radiations Radiat. Res. 179 2013 383 392
-
(2013)
Radiat. Res.
, vol.179
, pp. 383-392
-
-
Hunt, C.R.1
Ramnarain, D.2
Horikoshi, N.3
Iyenger, P.4
Pandita, R.K.5
Shay, J.W.6
Pandita, T.K.7
-
4
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
E.P. Rogakou, D.R. Pilch, A.H. Orr, V.S. Ivanova, and W.M. Bonner DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139 J. Biol. Chem. 273 1998 5858 5868
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
5
-
-
0019319471
-
Histone 2A, a heteromorphous family of eight protein species
-
M.H. West, and W.M. Bonner Histone 2A, a heteromorphous family of eight protein species Biochemistry 19 1980 3238 3245
-
(1980)
Biochemistry
, vol.19
, pp. 3238-3245
-
-
West, M.H.1
Bonner, W.M.2
-
6
-
-
22144448593
-
Histone H2A phosphorylation in DNA double-strand break repair
-
E.R. Foster, and J.A. Downs Histone H2A phosphorylation in DNA double-strand break repair FEBS J. 272 2005 3231 3240
-
(2005)
FEBS J.
, vol.272
, pp. 3231-3240
-
-
Foster, E.R.1
Downs, J.A.2
-
7
-
-
0343280013
-
A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage
-
T.T. Paull, E.P. Rogakou, V. Yamazaki, C.U. Kirchgessner, M. Gellert, and W.M. Bonner A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage Curr. Biol. 10 2000 886 895
-
(2000)
Curr. Biol.
, vol.10
, pp. 886-895
-
-
Paull, T.T.1
Rogakou, E.P.2
Yamazaki, V.3
Kirchgessner, C.U.4
Gellert, M.5
Bonner, W.M.6
-
8
-
-
33646106590
-
GammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
-
M. Stucki, and S.P. Jackson GammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes DNA Repair (Amst) 5 2006 534 543
-
(2006)
DNA Repair (Amst)
, vol.5
, pp. 534-543
-
-
Stucki, M.1
Jackson, S.P.2
-
9
-
-
77955841541
-
Focus on histone variant H2AX: To be or not to be
-
J. Yuan, R. Adamski, and J. Chen Focus on histone variant H2AX: to be or not to be FEBS Lett. 584 2010 3717 3724
-
(2010)
FEBS Lett.
, vol.584
, pp. 3717-3724
-
-
Yuan, J.1
Adamski, R.2
Chen, J.3
-
10
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
A. Celeste Genomic instability in mice lacking histone H2AX Science 296 2002 922 927
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
-
11
-
-
77951201429
-
DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression
-
J. An DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression BMC Mol. Biol. 11 2010 18
-
(2010)
BMC Mol. Biol.
, vol.11
, pp. 18
-
-
An, J.1
-
12
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
S. Burma, B.P. Chen, M. Murphy, A. Kurimasa, and D.J. Chen ATM phosphorylates histone H2AX in response to DNA double-strand breaks J. Biol. Chem. 276 2001 42462 42467
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
13
-
-
1642280957
-
UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress
-
I.M. Ward, K. Minn, and J. Chen UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress J. Biol. Chem. 279 2004 9677 9680
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9677-9680
-
-
Ward, I.M.1
Minn, K.2
Chen, J.3
-
14
-
-
11144305946
-
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors
-
H. Wang, M. Wang, H. Wang, W. Bocker, and G. Iliakis Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA-PK in human cells exposed to ionizing radiation and treated with kinase inhibitors J. Cell Physiol. 202 2005 492 502
-
(2005)
J. Cell Physiol.
, vol.202
, pp. 492-502
-
-
Wang, H.1
Wang, M.2
Wang, H.3
Bocker, W.4
Iliakis, G.5
-
15
-
-
3242878706
-
NBS1 and its functional role in the DNA damage response
-
J. Kobayashi, A. Antoccia, H. Tauchi, S. Matsuura, and K. Komatsu NBS1 and its functional role in the DNA damage response DNA Repair (Amst) 3 2004 855 861
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 855-861
-
-
Kobayashi, J.1
Antoccia, A.2
Tauchi, H.3
Matsuura, S.4
Komatsu, K.5
-
16
-
-
31444445458
-
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery
-
M.C. Keogh A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery Nature 439 2006 497 501
-
(2006)
Nature
, vol.439
, pp. 497-501
-
-
Keogh, M.C.1
-
17
-
-
84881243042
-
GammaH2AX as a marker of DNA double strand breaks and genomic instability in human population studies
-
V. Valdiglesias, S. Giunta, M. Fenech, M. Neri, and S. Bonassi GammaH2AX as a marker of DNA double strand breaks and genomic instability in human population studies Mutat. Res. 753 2013 24 40
-
(2013)
Mutat. Res.
, vol.753
, pp. 24-40
-
-
Valdiglesias, V.1
Giunta, S.2
Fenech, M.3
Neri, M.4
Bonassi, S.5
-
18
-
-
80053439127
-
Phosphorylated H2Ax is not an unambiguous marker for DNA double-strand breaks
-
J.E. Cleaver, L. Feeney, and I. Revet Phosphorylated H2Ax is not an unambiguous marker for DNA double-strand breaks Cell Cycle 10 2011 3223 3224
-
(2011)
Cell Cycle
, vol.10
, pp. 3223-3224
-
-
Cleaver, J.E.1
Feeney, L.2
Revet, I.3
-
19
-
-
79957705193
-
Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents
-
I. Revet, L. Feeney, S. Bruguera, W. Wilson, T.K. Dong, D.H. Oh, D. Dankort, and J.E. Cleaver Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents Proc. Natl. Acad. Sci. USA 108 2011 8663 8667
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 8663-8667
-
-
Revet, I.1
Feeney, L.2
Bruguera, S.3
Wilson, W.4
Dong, T.K.5
Oh, D.H.6
Dankort, D.7
Cleaver, J.E.8
-
20
-
-
47849120976
-
Serum starvation induces H2AX phosphorylation to regulate apoptosis via p38 MAPK pathway
-
C. Lu, Y. Shi, Z. Wang, Z. Song, M. Zhu, Q. Cai, and T. Chen Serum starvation induces H2AX phosphorylation to regulate apoptosis via p38 MAPK pathway FEBS Lett. 582 2008 2703 2708
-
(2008)
FEBS Lett.
, vol.582
, pp. 2703-2708
-
-
Lu, C.1
Shi, Y.2
Wang, Z.3
Song, Z.4
Zhu, M.5
Cai, Q.6
Chen, T.7
-
21
-
-
26244439873
-
ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells
-
K.J. McManus, and M.J. Hendzel ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells Mol. Biol. Cell 16 2005 5013 5025
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 5013-5025
-
-
McManus, K.J.1
Hendzel, M.J.2
-
22
-
-
84866747992
-
4E-BP1 participates in maintaining spindle integrity and genomic stability via interacting with PLK1
-
Z.F. Shang 4E-BP1 participates in maintaining spindle integrity and genomic stability via interacting with PLK1 Cell Cycle 11 2012 3463 3471
-
(2012)
Cell Cycle
, vol.11
, pp. 3463-3471
-
-
Shang, Z.F.1
-
23
-
-
77951971957
-
The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells
-
A. Stolz The CHK2-BRCA1 tumour suppressor pathway ensures chromosomal stability in human somatic cells Nat. Cell Biol. 12 2010 492 499
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 492-499
-
-
Stolz, A.1
-
24
-
-
0036903037
-
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1
-
O. Fernandez-Capetillo DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1 Nat. Cell Biol. 4 2002 993 997
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 993-997
-
-
Fernandez-Capetillo, O.1
-
25
-
-
77957329930
-
Chk-ing in and Chk-ing out: Kinase compartmentalization comes to checkpoint control
-
D.A. Canton, and J.D. Scott Chk-ing in and Chk-ing out: kinase compartmentalization comes to checkpoint control Mol. Cell 40 2010 1 2
-
(2010)
Mol. Cell
, vol.40
, pp. 1-2
-
-
Canton, D.A.1
Scott, J.D.2
-
26
-
-
0037424258
-
Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody
-
L. Tsvetkov, X. Xu, J. Li, and D.F. Stern Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody J. Biol. Chem. 278 2003 8468 8475
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8468-8475
-
-
Tsvetkov, L.1
Xu, X.2
Li, J.3
Stern, D.F.4
-
27
-
-
33750692709
-
GammaH2AX and its role in DNA double-strand break repair
-
J. Fillingham, M.C. Keogh, and N.J. Krogan GammaH2AX and its role in DNA double-strand break repair Biochem. Cell Biol. 84 2006 568 577
-
(2006)
Biochem. Cell Biol.
, vol.84
, pp. 568-577
-
-
Fillingham, J.1
Keogh, M.C.2
Krogan, N.J.3
-
28
-
-
84878435307
-
Cell cycle-dependent localization of CHK2 at centrosomes during mitosis
-
G. Chouinard, I. Clement, J. Lafontaine, F. Rodier, and E. Schmitt Cell cycle-dependent localization of CHK2 at centrosomes during mitosis Cell Div. 8 2013 7
-
(2013)
Cell Div.
, vol.8
, pp. 7
-
-
Chouinard, G.1
Clement, I.2
Lafontaine, J.3
Rodier, F.4
Schmitt, E.5
-
29
-
-
15744386741
-
Regulation of CHK2 by DNA-dependent protein kinase
-
J. Li, and D.F. Stern Regulation of CHK2 by DNA-dependent protein kinase J. Biol. Chem. 280 2005 12041 12050
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12041-12050
-
-
Li, J.1
Stern, D.F.2
-
30
-
-
28444483130
-
Gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair
-
D. Chowdhury, M.C. Keogh, H. Ishii, C.L. Peterson, S. Buratowski, and J. Lieberman Gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair Mol. Cell 20 2005 801 809
-
(2005)
Mol. Cell
, vol.20
, pp. 801-809
-
-
Chowdhury, D.1
Keogh, M.C.2
Ishii, H.3
Peterson, C.L.4
Buratowski, S.5
Lieberman, J.6
-
31
-
-
80053436648
-
Serine/threonine protein phosphatases in DNA damage response
-
B. Liu, and X.-Z. Xu Serine/threonine protein phosphatases in DNA damage response Chinese Sci. Bull. 56 2011 3122 3131
-
(2011)
Chinese Sci. Bull.
, vol.56
, pp. 3122-3131
-
-
Liu, B.1
Xu, X.-Z.2
-
32
-
-
80052282497
-
ATM-mediated phosphorylation activates the tumor-suppressive function of B56gamma-PP2A
-
G.P. Shouse, Y. Nobumori, M.J. Panowicz, and X. Liu ATM-mediated phosphorylation activates the tumor-suppressive function of B56gamma-PP2A Oncogene 30 2011 3755 3765
-
(2011)
Oncogene
, vol.30
, pp. 3755-3765
-
-
Shouse, G.P.1
Nobumori, Y.2
Panowicz, M.J.3
Liu, X.4
-
33
-
-
53249100305
-
PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint
-
S. Nakada, G.I. Chen, A.C. Gingras, and D. Durocher PP4 is a gamma H2AX phosphatase required for recovery from the DNA damage checkpoint EMBO Rep. 9 2008 1019 1026
-
(2008)
EMBO Rep.
, vol.9
, pp. 1019-1026
-
-
Nakada, S.1
Chen, G.I.2
Gingras, A.C.3
Durocher, D.4
-
34
-
-
46149117962
-
A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication
-
D. Chowdhury A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication Mol. Cell 31 2008 33 46
-
(2008)
Mol. Cell
, vol.31
, pp. 33-46
-
-
Chowdhury, D.1
-
35
-
-
84861399281
-
Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage
-
F. Merolla, C. Luise, M.T. Muller, R. Pacelli, A. Fusco, and A. Celetti Loss of CCDC6, the first identified RET partner gene, affects pH2AX S139 levels and accelerates mitotic entry upon DNA damage PLoS One 7 2012 e36177
-
(2012)
PLoS One
, vol.7
, pp. 36177
-
-
Merolla, F.1
Luise, C.2
Muller, M.T.3
Pacelli, R.4
Fusco, A.5
Celetti, A.6
-
36
-
-
84870524558
-
FBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cells
-
J. Zhao, J. Tang, W. Men, and K. Ren FBXW7-mediated degradation of CCDC6 is impaired by ATM during DNA damage response in lung cancer cells FEBS Lett. 586 2012 4257 4263
-
(2012)
FEBS Lett.
, vol.586
, pp. 4257-4263
-
-
Zhao, J.1
Tang, J.2
Men, W.3
Ren, K.4
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