Loss of Oca2 disrupts the unfolded protein response and increases resistance to endoplasmic reticulum stress in melanocytes

Pigment Cell and Melanoma Research

Volumn 26, Issue 6, 2013, Pages 826-834

  Cheng, Tsing ^a   Orlow, Seth J ^a   Manga, Prashiela ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

eIF2 ; ER stress; Melanocyte; Oculocutaneous albinism type 2; Unfolded protein response

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 34; GUANABENZ; INITIATION FACTOR 2ALPHA; MONOPHENOL MONOOXYGENASE; OCA2 PROTEIN; PERK PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 1ALPHA; THAPSIGARGIN; TRANSCRIPTION FACTOR; TUMOR PROTEIN; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG SENSITIVITY; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; MELANOCYTE; NONHUMAN; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE;

EIF2Α; ER STRESS; MELANOCYTE; OCULOCUTANEOUS ALBINISM TYPE 2; UNFOLDED PROTEIN RESPONSE;

ANIMALS; APOPTOSIS; CARRIER PROTEINS; CELL LINE; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; GUANABENZ; MELANOCYTES; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICE; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; THAPSIGARGIN; UNFOLDED PROTEIN RESPONSE;

EID: 84886294897     PISSN: 17551471     EISSN: 1755148X     Source Type: Journal    
DOI: 10.1111/pcmr.12158     Document Type: Article

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