메뉴 건너뛰기




Volumn 132, Issue 11, 2012, Pages 2601-2609

Vitiligo-inducing phenols activate the unfolded protein response in melanocytes resulting in upregulation of IL6 and IL8

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 6; INTERLEUKIN 8; MONOBENZONE; PHENOL DERIVATIVE; PROTEIN KINASE; PROTEIN KINASE RNA LIKE ENDOPLASMIC RETICULUM KINASE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

EID: 84867848664     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2012.181     Document Type: Article
Times cited : (145)

References (52)
  • 1
    • 46749110086 scopus 로고    scopus 로고
    • Cytokine secretion in longstanding diabetes mellitus type 1 and 2: Associations with low-grade systemic inflammation
    • Alexandraki KI, Piperi C, Ziakas PD et al. (2008) Cytokine secretion in longstanding diabetes mellitus type 1 and 2: associations with low-grade systemic inflammation. J Clin Immunol 28:314-21
    • (2008) J Clin Immunol , vol.28 , pp. 314-321
    • Alexandraki, K.I.1    Piperi, C.2    Ziakas, P.D.3
  • 3
    • 33746583601 scopus 로고    scopus 로고
    • Increased tumor necrosis factor alpha (TNF-α) and interleukin 1 alpha (IL1-α) levels in the lesional skin of patients with nonsegmental vitiligo [6]
    • DOI 10.1111/j.1365-4632.2006.02744.x
    • Birol A, Kisa U, Kurtipek GS et al. (2006) Increased tumor necrosis factor alpha (TNF-alpha) and interleukin 1 alpha (IL1-alpha) levels in the lesional skin of patients with nonsegmental vitiligo. Int J Dermatol 45:992-3 (Pubitemid 44145043)
    • (2006) International Journal of Dermatology , vol.45 , Issue.8 , pp. 992-993
    • Birol, A.1    Kisa, U.2    Kurtipek, G.S.3    Kara, F.4    Kocak, M.5    Erkek, E.6    Caglayan, O.7
  • 4
    • 0025915732 scopus 로고
    • Structural aberration of the rough endoplasmic reticulum and melanosome compartmentalization in longterm cultures of melanocytes from vitiligo patients
    • Boissy RE, Liu YY, Medrano EE et al. (1991) Structural aberration of the rough endoplasmic reticulum and melanosome compartmentalization in longterm cultures of melanocytes from vitiligo patients. J Invest Dermatol 97:395-404
    • (1991) J Invest Dermatol , vol.97 , pp. 395-404
    • Boissy, R.E.1    Liu, Y.Y.2    Medrano, E.E.3
  • 5
    • 2642539089 scopus 로고    scopus 로고
    • On the etiology of contact/occupational vitiligo
    • DOI 10.1111/j.1600-0749.2004.00130.x
    • Boissy RE, Manga P (2004) On the etiology of contact/occupational vitiligo. Pigment Cell Res 17:208-14 (Pubitemid 38724550)
    • (2004) Pigment Cell Research , vol.17 , Issue.3 , pp. 208-214
    • Boissy, R.E.1    Manga, P.2
  • 6
    • 2442542312 scopus 로고    scopus 로고
    • PERK-dependent Activation of Nrf2 Contributes to Redox Homeostasis and Cell Survival following Endoplasmic Reticulum Stress
    • DOI 10.1074/jbc.M314219200
    • Cullinan SB, Diehl JA (2004) PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J Biol Chem 279:20108-17 (Pubitemid 38623455)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.19 , pp. 20108-20117
    • Cullinan, S.B.1    Diehl, J.A.2
  • 7
    • 29244462498 scopus 로고    scopus 로고
    • Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway
    • DOI 10.1016/j.biocel.2005.09.018, PII S1357272505003055
    • Cullinan SB, Diehl JA (2006) Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway. Int J Biochem Cell Biol 38:317-32 (Pubitemid 41821881)
    • (2006) International Journal of Biochemistry and Cell Biology , vol.38 , Issue.3 , pp. 317-332
    • Cullinan, S.B.1    Diehl, J.A.2
  • 8
    • 79956063285 scopus 로고    scopus 로고
    • Heme oxygenase-1 expression protects melanocytes from stress-induced cell death: Implications for vitiligo
    • Elassiuty YE, Klarquist J, Speiser J et al. (2011) Heme oxygenase-1 expression protects melanocytes from stress-induced cell death: implications for vitiligo. Exp Dermatol 20:496-501
    • (2011) Exp Dermatol , vol.20 , pp. 496-501
    • Elassiuty, Y.E.1    Klarquist, J.2    Speiser, J.3
  • 9
    • 70449494871 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in beta-cells and development of diabetes
    • Fonseca SG, Burcin M, Gromada J et al. (2009) Endoplasmic reticulum stress in beta-cells and development of diabetes. Curr Opin Pharmacol 9:763-70
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 763-770
    • Fonseca, S.G.1    Burcin, M.2    Gromada, J.3
  • 10
    • 33748121115 scopus 로고    scopus 로고
    • Interleukin-6 and chronic inflammation
    • Gabay C (2006) Interleukin-6 and chronic inflammation. Arthritis Res Ther 8(Suppl 2):S3
    • (2006) Arthritis Res Ther , vol.8 , Issue.SUPPL. 2
    • Gabay, C.1
  • 12
    • 79957481405 scopus 로고    scopus 로고
    • Interleukin-11, an IL-6 like cytokine
    • Guk KD, Kuprash DV (2011) [Interleukin-11, an IL-6 like cytokine]. Mol Biol (Mosk) 45:44-55
    • (2011) Mol Biol (Mosk) , vol.45 , pp. 44-55
    • Guk, K.D.1    Kuprash, D.V.2
  • 13
    • 72049106379 scopus 로고    scopus 로고
    • Monobenzyl ether of hydroquinone and 4-tertiary butyl phenol activate markedly different physiological responses in melanocytes: Relevance to skin depigmentation
    • Hariharan V, Klarquist J, Reust MJ et al. (2010) Monobenzyl ether of hydroquinone and 4-tertiary butyl phenol activate markedly different physiological responses in melanocytes: relevance to skin depigmentation. J Invest Dermatol 130:211-20
    • (2010) J Invest Dermatol , vol.130 , pp. 211-220
    • Hariharan, V.1    Klarquist, J.2    Reust, M.J.3
  • 15
    • 0036694589 scopus 로고    scopus 로고
    • IL-6 in autoimmune disease and chronic inflammatory proliferative disease
    • Ishihara K, Hirano T (2002) IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev 13:357-68
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 357-368
    • Ishihara, K.1    Hirano, T.2
  • 16
    • 0017695235 scopus 로고
    • Occupational vitiligo induced by p-tert-butylphenol, a systemic disease?
    • James O, Mayes RW, Stevenson CJ (1977) Occupational vitiligo induced by p-tert-butylphenol, a systemic disease. Lancet 2:1217-9 (Pubitemid 8237205)
    • (1977) Lancet , vol.2 , Issue.8050 , pp. 1217-1219
    • James, O.1    Mayes, R.W.2    Stevenson, C.J.3
  • 17
    • 79958856350 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects human melanocytes from H2O2-induced oxidative stress via the Nrf2-ARE pathway
    • Jian Z, Li K, Liu L et al. (2011) Heme oxygenase-1 protects human melanocytes from H2O2-induced oxidative stress via the Nrf2-ARE pathway. J Invest Dermatol 131:1420-7
    • (2011) J Invest Dermatol , vol.131 , pp. 1420-1427
    • Jian, Z.1    Li, K.2    Liu, L.3
  • 18
  • 19
    • 0026505973 scopus 로고
    • Modulation of intercellular adhesion molecule-1 expression on human melanocytes and melanoma cells: Evidence for a regulatory role of IL-6, IL-7, TNF beta, and UVB light
    • Kirnbauer R, Charvat B, Schauer E et al. (1992) Modulation of intercellular adhesion molecule-1 expression on human melanocytes and melanoma cells: evidence for a regulatory role of IL-6, IL-7, TNF beta, and UVB light. J Invest Dermatol 98:320-6
    • (1992) J Invest Dermatol , vol.98 , pp. 320-326
    • Kirnbauer, R.1    Charvat, B.2    Schauer, E.3
  • 20
    • 0026532514 scopus 로고
    • Characterization of T-cell subsets, soluble interleukin-2 receptors and interleukin-6 in Vogt-Koyanagi- Harada disease
    • Kogiso M, Tanouchi Y, Miki S et al. (1992) Characterization of T-cell subsets, soluble interleukin-2 receptors and interleukin-6 in Vogt-Koyanagi- Harada disease. Jpn J Ophthalmol 36:37-43
    • (1992) Jpn J Ophthalmol , vol.36 , pp. 37-43
    • Kogiso, M.1    Tanouchi, Y.2    Miki, S.3
  • 21
    • 0029176980 scopus 로고
    • Growth control of melanoma cells and melanocytes by cytokines
    • Krasagakis K, Garbe C, Zouboulis CC et al. (1995) Growth control of melanoma cells and melanocytes by cytokines. Recent Results Cancer Res 139:169-82
    • (1995) Recent Results Cancer Res , vol.139 , pp. 169-182
    • Krasagakis, K.1    Garbe, C.2    Zouboulis, C.C.3
  • 25
    • 0029932239 scopus 로고    scopus 로고
    • Presence of T cells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance
    • Le Poole IC, van den Wijngaard RM, Westerhof W et al. (1996) Presence of T cells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance. Am J Pathol 148:1219-28 (Pubitemid 26108257)
    • (1996) American Journal of Pathology , vol.148 , Issue.4 , pp. 1219-1228
    • Le Poole, I.C.1    Van Den Wijngaard, R.M.2    Westerhof, W.3    Das, P.K.4
  • 26
    • 0034523075 scopus 로고    scopus 로고
    • IgG anti-melanocyte antibodies purified from patients with active vitiligo induce HLA-DR and intercellular adhesion molecule-1 expression and an increase in interleukin-8 release by melanocytes
    • Li YL, Yu CL, Yu HS (2000) IgG anti-melanocyte antibodies purified from patients with active vitiligo induce HLA-DR and intercellular adhesion molecule-1 expression and an increase in interleukin-8 release by melanocytes. J Invest Dermatol 115:969-73
    • (2000) J Invest Dermatol , vol.115 , pp. 969-973
    • Li, Y.L.1    Yu, C.L.2    Yu, H.S.3
  • 27
    • 33646166752 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-induced apoptosis and auto-immunity in diabetes
    • Lipson KL, Fonseca SG, Urano F (2006) Endoplasmic reticulum stress-induced apoptosis and auto-immunity in diabetes. Curr Mol Med 6:71-7
    • (2006) Curr Mol Med , vol.6 , pp. 71-77
    • Lipson, K.L.1    Fonseca, S.G.2    Urano, F.3
  • 28
    • 34447548783 scopus 로고    scopus 로고
    • Heme oxygenase-1 inhibits T cell-dependent skin inflammation and differentiation and function of antigen-presenting cells
    • DOI 10.1111/j.1600-0625.2007.00581.x
    • Listopad J, Asadullah K, Sievers C et al. (2007) Heme oxygenase-1 inhibits T cell-dependent skin inflammation and differentiation and function of antigen-presenting cells. Exp Dermatol 16:661-70 (Pubitemid 47079596)
    • (2007) Experimental Dermatology , vol.16 , Issue.8 , pp. 661-670
    • Listopad, J.1    Asadullah, K.2    Sievers, C.3    Ritter, T.4    Meisel, C.5    Sabat, R.6    Docke, W.-D.7
  • 29
    • 38049010534 scopus 로고    scopus 로고
    • A role for tyrosinase-related protein 1 in 4-tert-butylphenol-induced toxicity in melanocytes: Implications for vitiligo
    • DOI 10.2353/ajpath.2006.050769
    • Manga P, Sheyn D, Yang F et al. (2006) A role for tyrosinase-related protein 1 in 4-tert-butylphenol-induced toxicity in melanocytes: Implications for vitiligo. Am J Pathol 169:1652-62 (Pubitemid 351181997)
    • (2006) American Journal of Pathology , vol.169 , Issue.5 , pp. 1652-1662
    • Manga, P.1    Sheyn, D.2    Yang, F.3    Sarangarajan, R.4    Boissy, R.E.5
  • 30
    • 77951177952 scopus 로고    scopus 로고
    • The UPR and cell fate at a glance
    • Merksamer PI, Papa FR (2010) The UPR and cell fate at a glance. J Cell Sci 123:1003-6
    • (2010) J Cell Sci , vol.123 , pp. 1003-1006
    • Merksamer, P.I.1    Papa, F.R.2
  • 31
    • 68849103736 scopus 로고    scopus 로고
    • Keratinocyte dysfunction in vitiligo epidermis: Cytokine microenvironment and correlation to keratinocyte apoptosis
    • Moretti S, Fabbri P, Baroni G et al. (2009) Keratinocyte dysfunction in vitiligo epidermis: cytokine microenvironment and correlation to keratinocyte apoptosis. Histol Histopathol 24:849-57
    • (2009) Histol Histopathol , vol.24 , pp. 849-857
    • Moretti, S.1    Fabbri, P.2    Baroni, G.3
  • 33
    • 67649402187 scopus 로고    scopus 로고
    • The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress
    • Nguyen T, Nioi P, Pickett CB (2009) The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem 284:13291-5
    • (2009) J Biol Chem , vol.284 , pp. 13291-13295
    • Nguyen, T.1    Nioi, P.2    Pickett, C.B.3
  • 34
    • 0021800813 scopus 로고
    • Dermatitis produced by applications of monobenzone in patients with active vitiligo
    • DOI 10.1001/archderm.121.9.1141
    • Nordlund JJ, Forget B, Kirkwood J et al. (1985) Dermatitis produced by applications of monobenzone in patients with active vitiligo. Arch Dermatol 121:1141-4 (Pubitemid 15018898)
    • (1985) Archives of Dermatology , vol.121 , Issue.9 , pp. 1141-1144
    • Nordlund, J.J.1    Forget, B.2    Kirkwood, J.3    Lerner, A.B.4
  • 36
    • 77951427546 scopus 로고    scopus 로고
    • Rapamycin inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver
    • Pfaffenbach KT, Nivala AM, Reese L et al. (2010) Rapamycin inhibits postprandial-mediated X-box-binding protein-1 splicing in rat liver. J Nutr 140:879-84
    • (2010) J Nutr , vol.140 , pp. 879-884
    • Pfaffenbach, K.T.1    Nivala, A.M.2    Reese, L.3
  • 37
    • 67651233779 scopus 로고    scopus 로고
    • Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo
    • Ren Y, Yang S, Xu S et al. (2009) Genetic variation of promoter sequence modulates XBP1 expression and genetic risk for vitiligo. PLoS Genet 5:e1000523
    • (2009) PLoS Genet , vol.5
    • Ren, Y.1    Yang, S.2    Xu, S.3
  • 38
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • DOI 10.1038/nrm2199, PII NRM2199
    • Ron D, Walter P (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8:519-29 (Pubitemid 46985379)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.7 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 40
    • 77951542845 scopus 로고    scopus 로고
    • Sorafenib with doxorubicin augments cytotoxicity to renal cell cancer through PERK inhibition
    • Shiota M, Eto M, Yokomizo A et al. (2010) Sorafenib with doxorubicin augments cytotoxicity to renal cell cancer through PERK inhibition. Int J Oncol 36:1521-31
    • (2010) Int J Oncol , vol.36 , pp. 1521-1531
    • Shiota, M.1    Eto, M.2    Yokomizo, A.3
  • 41
    • 78751693010 scopus 로고    scopus 로고
    • The genetics of generalized vitiligo: Autoimmune pathways and an inverse relationship with malignant melanoma
    • Spritz RA (2010) The genetics of generalized vitiligo: autoimmune pathways and an inverse relationship with malignant melanoma. Genome Med 2:78
    • (2010) Genome Med , vol.2 , pp. 78
    • Spritz, R.A.1
  • 42
    • 50249116184 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress response in immunity and autoimmunity
    • Todd DJ, Lee AH, Glimcher LH (2008) The endoplasmic reticulum stress response in immunity and autoimmunity. Nat Rev Immunol 8:663-74
    • (2008) Nat Rev Immunol , vol.8 , pp. 663-674
    • Todd, D.J.1    Lee, A.H.2    Glimcher, L.H.3
  • 43
    • 79953288480 scopus 로고    scopus 로고
    • Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis
    • Tsaytler P, Harding HP, Ron D et al. (2011) Selective inhibition of a regulatory subunit of protein phosphatase 1 restores proteostasis. Science 332:91-4
    • (2011) Science , vol.332 , pp. 91-94
    • Tsaytler, P.1    Harding, H.P.2    Ron, D.3
  • 44
    • 0037291793 scopus 로고    scopus 로고
    • Increased interleukin-6 and granulocytemacrophage colony stimulating factor levels in the sera of patients with non-segmental vitiligo
    • Tu CX, Gu JS, Lin XR (2003) Increased interleukin-6 and granulocytemacrophage colony stimulating factor levels in the sera of patients with non-segmental vitiligo. J Dermatol Sci 31:73-8
    • (2003) J Dermatol Sci , vol.31 , pp. 73-78
    • Tu, C.X.1    Gu, J.S.2    Lin, X.R.3
  • 45
    • 70349731750 scopus 로고    scopus 로고
    • Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients
    • van den Boorn JG, Konijnenberg D, Dellemijn TA et al. (2009) Autoimmune destruction of skin melanocytes by perilesional T cells from vitiligo patients. J Invest Dermatol 129:2220-32
    • (2009) J Invest Dermatol , vol.129 , pp. 2220-2232
    • Van Den Boorn, J.G.1    Konijnenberg, D.2    Dellemijn, T.A.3
  • 46
    • 79955995581 scopus 로고    scopus 로고
    • Skin-depigmenting agent monobenzone induces potent T-cell autoimmunity toward pigmented cells by tyrosinase haptenation and melanosome autophagy
    • van den Boorn JG, Picavet DI, van Swieten PF et al. (2011) Skin-depigmenting agent monobenzone induces potent T-cell autoimmunity toward pigmented cells by tyrosinase haptenation and melanosome autophagy. J Invest Dermatol 131:1240-51
    • (2011) J Invest Dermatol , vol.131 , pp. 1240-1251
    • Van Den Boorn, J.G.1    Picavet, D.I.2    Van Swieten, P.F.3
  • 47
    • 79953319782 scopus 로고    scopus 로고
    • Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease
    • Volkmann K, Lucas JL, Vuga D et al. (2011) Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease. J Biol Chem 286:12743-55
    • (2011) J Biol Chem , vol.286 , pp. 12743-12755
    • Volkmann, K.1    Lucas, J.L.2    Vuga, D.3
  • 48
    • 34548555721 scopus 로고    scopus 로고
    • Vitiligo puzzle: The pieces fall in place
    • DOI 10.1111/j.1600-0749.2007.00399.x
    • Westerhof W, d'Ischia M (2007) Vitiligo puzzle: the pieces fall in place. Pigment Cell Res 20:345-59 (Pubitemid 47390114)
    • (2007) Pigment Cell Research , vol.20 , Issue.5 , pp. 345-359
    • Westerhof, W.1    D'Ischia, M.2
  • 49
    • 77956950124 scopus 로고    scopus 로고
    • Subtoxic levels hydrogen peroxideinduced production of interleukin-6 by retinal pigment epithelial cells
    • Wu WC, Hu DN, Gao HX et al. (2010) Subtoxic levels hydrogen peroxideinduced production of interleukin-6 by retinal pigment epithelial cells. Mol Vis 16:1864-73
    • (2010) Mol Vis , vol.16 , pp. 1864-1873
    • Wu, W.C.1    Hu, D.N.2    Gao, H.X.3
  • 52
    • 85052661690 scopus 로고    scopus 로고
    • Alterations in IL-6, IL-8, GM-CSF, TNFalpha, and IFN-gamma release by peripheral mononuclear cells in patients with active vitiligo
    • Yu HS, Chang KL, Yu CL et al. (1997) Alterations in IL-6, IL-8, GM-CSF, TNFalpha, and IFN-gamma release by peripheral mononuclear cells in patients with active vitiligo. J Invest Dermatol 108:527-9
    • (1997) J Invest Dermatol , vol.108 , pp. 527-529
    • Yu, H.S.1    Chang, K.L.2    Yu, C.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.