Occurrence and estimation of aflatoxin M1 exposure in milk in Serbia

Food Control

Volumn 38, Issue 1, 2014, Pages 41-46

  Kos, Jovana ^a   Lević, Jovanka ^a   Duragić, Olivera ^a   Kokić, Bojana ^a   Miladinović, Ivana ^a  

^a UNIVERSITY OF NOVI SAD   (Serbia)

Author keywords

Aflatoxin M1; Exposure; Milk; Serbia

Indexed keywords

CAPRA HIRCUS; EQUUS ASINUS;

EID: 84886256935     PISSN: 09567135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.foodcont.2013.09.060     Document Type: Article

References (48)

1. Ardic M., Karakaya Y., Atasever M., Durmaz H. Determination of aflatoxin B1 levels in deep-red ground pepper (isot) using immunoaffinity column combined with ELISA. Food and Chemical Toxicology 2008, 46:1596-1599.
2. Ayar A., Sert D., Con A.H. Astudy on the occurrence of aflatoxin in raw milk due to feeds. Journal of Food Safety 2007, 27:199-207.
3. Barbiroli A., Bonomi F., Benedetti S., Mannino S., Monti L., Cattaneo T., et al. Binding of aflatoxin M1 to different protein fractions in ovine and caprine milk. Journal of Dairy Science 2007, 90:532-540.
4. Berkum S.V. Agriculture in late transition - Experience of Serbia. Integrating into the EU: Challenges for the Serbian dairy supply chain 2010, (Chapter VI), Published by the Serbian Association of Agricultural Economists - DAES (SAAE), Belgrade, Republic of Serbia.
5. Bilandžić N., Varenina I., Solomun B. Aflatoxin M1 in raw milk in Croatia. Food Control 2010, 21:1279-1281.
6. Božić D., Muncan P., Sevarlić M. An assessment of the competitiveness of the dairy supply chain in Serbia 2009, Report in the framework of the FP7 EU financed project AgriPolicy. http://www.agripolicy.net.
7. Cano-Sancho G., Marin S., Ramos A.J., Peris-Vicente J., Sanchis V. Occurrence of aflatoxin M1 and exposure assessment in Catalonia (Spain). Revista Iberoamericana de Micología 2010, 27:130-135.
8. Colak H. Determination of aflatoxin M1 levels in Turkish white and Kashar cheeses made of experimentally contaminated raw milk. Journal of Food and Drug Analysis 2007, 15(2):163-168.
9. Decastelli L., Lai J., Gramaglia M., Monaco A., Nachtmann C., Oldano F. Aflatoxins occurrence in milk and feed in Northern Italy during 2004-2005. Food Control 2007, 18:1263-1266.
10. Dowling S., Brown A. An exploration of the experiences of mothers who breastfeed long-term: what are the issues and why does it matter?. Breastfeeding Medicine 2012, 8:45-52.
11. Duarte S.C., Almeida A.M., Teixeira A.S., Pereira A.L., Falcão A.C., Pena A., et al. Aflatoxin M1 in marketed milk in Portugal: Assessment of human and animal exposure. Food Control 2013, 30:411-417.
12. EFSA Report for 2010 on the results from the monitoring of veterinary medicinal product residues and other substances in live animals and animal products. The EFSA Journal 2010, 212:1-64.
13. Erkekoǧlu P., Şahin G., Baydar T. Aspecial focus on mycotoxin contamination in baby foods: their presence and regulations, review article, FABAD. Journal of Pharmaceutical Science 2008, 33:51-66.
14. Commission Regulation 2002/32/EC of 7 May 2002 on undesirable substances in animal feed. Official Journal of the European Parliament 2002, L 140:10-21. European Commission.
15. Commission Regulation 2002/657/EC of 14 August 2002 implementing council directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Official Journal of the European Communities 2002, L 221:8-36. European Commission.
16. Commission Regulation 401/2006 of 23 February 2006 laying down the methods of sampling and analysis for the official control of the levels of mycotoxins in foodstuffs. Official Journal of the European Union 2006, L 70:12-34. European Commission.
17. Commission Regulation 1881/2006 of 19 December2006 setting maximum levels for certain contaminants in foodstuffs as regards Fusarium toxins in maize and maize products. Official Journal of the European Union 2006, L 364:5-18. European Commission.
18. Fallah A.A., Jafari T., Fallah A., Rahnama M. Determination of aflatoxin M1 levels in Iranian white and cream cheese. Food and Chemical Toxicology 2009, 47:1872-1875.
19. Fallah A.A., Rahnama M., Jafari T., Saei-Dehkordi S.S. Seasonal variation of aflatoxin M1 contamination in industrial and traditional Iranian dairy products. Food Control 2011, 22(10):1653-1656.
20. FDA U.S.Food and Drug Administration Guidance for industry: Action levels for poisonous or deleterious substances in human food and animal feed 2011, Available from. http://www.fda.gov/Food/GuidanceComplianceRegulatoryInformation/GuidanceDocuments/ChemicalContaminantsandPesticides/ucm077969.htm.
21. Ghidini S., Zanardi E., Battaglia A., Varisco G., Ferretti E., Campanini G., et al. Comparison of contaminant and residue levels in organic and conventional milk and meat products from Northern Italy. Food and Additives Contaminants 2005, 22(1):9-14.
22. Gurbay A., Sabuncuoglu S.A., Girgin G., Sahin G., Yigit S., Yurdakok M., et al. Exposure of newborns to aflatoxin M1 and B1 from mothers breast milk in Ankara, Turkey. Food and Chemical Toxicology 2010, 48:314-319.
23. Hussain I., Anwar J., Asi M.R., Munawar M.A., Kashif M. Aflatoxin M1 contamination in milk from five dairy species in Pakistan. Food Control 2010, 21:122-124.
24. Some naturally occurring substances: Food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC monograph on the evaluation of carcinogenic risks to humans 1993, Vol. 56:19-23. IARC, International Agency for Research on Cancer, World Health Organization, IARC, Lyon, France.
25. Monograph on the evaluation of carcinogenic risk to humans 2002, Vol. 82:171. IARC, International Agency for Research on Cancer, World Health Organization, IARC, Lyon, France.
26. Ivakhnenko O., Nyankovskyy S. Nutritional status of babies and influence of unmodified cow's milk on allergic reactions according to the epidemiological study from Ukraine. Pediatria Polska 2013, 88:138-143.
27. Janković V.V., Vukojević J.B., Lakićević B.M., Mitrović R.R., Vuković D.I. Presence of moulds and aflatoxin m1 in milk. Proceedings for natural science, Matica Srpska Novi Sad 2009, Vol. 117:63-68.
28. JECFA Safety evaluation of certain mycotoxins in food. Prepared by the fifty sixty meeting of the Joint FAO/WHO Expert Committee on food additives in food additives series 2001, Vol. 47. WHO, Geneva.
29. Kokić B., Čabarkapa I., Lević J., Mandić A., Matić J., Ivanov D. Screening of mycotoxins in animal feed from the region of Vojvodina. Proceedings for natural science, Matica Srpska Novi Sad 2009, Vol. 117:87-96.
30. Kos J., Mastilović J., Hajnal J.E., Šarić B. Natural occurrence of aflatoxins in maize harvested in Serbia during 2009-2012. Food Control 2013, 34:31-34.
31. Kuiper-Goodman T. Uncertainties in the risk assessment of three mycotoxins: aflatoxin, ochratoxin and zearalenone. Canadian Journal of Physiology and Pharmacology 1990, 68:1017-1024.
32. Leblanc J.C., Tard A., Volatier J.L., Verger P. Estimated dietary exposure to principal food mycotoxins from the first French total diet study. Food Additives and Contaminants: Part A 2005, 22:652-672.
33. Lević J., Duragić O., Kos J., Varga J., Bagi F. The occurrence of aflatoxins in Serbia-from feed to food. The second North and East European Congress on food, Kiev, Ukraine, May 26-29 2013, 77.
34. Maslac T. US Department of Agriculture (USDA) grain and feed annual 2011, Annual report on wheat, corn and barley for Serbia.
35. Matić J., Mandić A., Lević J., Zdjelar G., Vasiljević I., Kokić B., et al. Occurrence of mycotoxins and genetically modified organisms in feed and food containing corn and soybean. XIV International symposium feed technology, Novi Sad 19-21 October, Serbia 2010, 288-294.
36. Meucci V., Razzuoli E., Soldani G., Massart F. Mycotoxin detection in infant formula milks in Italy. Food Additives and Contaminants: Part A 2010, 27:64-71.
37. Oruc H.H., Cibik R., Yilmaz E., Kalkanli O. Distribution and stability of aflatoxin M1 during processing and ripening of traditional white pickled cheese. Food Additives and Contaminants 2006, 23(2):190-195.
38. Polovinski-Horvatović M., Jurić V., Glamočić D. Two year study of incidence of aflatoxin M1 in milk in the region of Serbia. Biotechnology in Animal Husbandry. 2010, 25(5-6):713-718.
39. Serbian Regulation Quality of feed. Official Bulletin of the Republic of Serbia 2010, 4/10:1-64.
40. Serbian Regulation Quality of dietary supplements. Official Bulletin of the Republic of Serbia 2010, 45/10:1-74.
41. Serbian Regulation Maximum allowed contents of contaminants in food and feed. Official Bulletin of the Republic of Serbia 2011, 28/11:1-16.
42. Serbian Regulation Maximum allowed contents of contaminants in food and feed. Official Bulletin of the Republic of Serbia 2013, 20/13:1.
43. Shundo L., Navas S.A., Lamardo L.C.A., Ruvieri V., Sabino M. Estimate of aflatoxin M1 exposure in milk and occurrence in Brazil. Food Control 2009, 20:655-657.
44. Tsakiris I.N., Tzatzarakis M.N., Alegakis A.K., Vlachou M.V., Renieri E.A., Tsatsakis A.,M. Risk assessment scenarios of children's exposure to aflatoxin M1 residues in different milk types from the Greek market. Food and Chemical Toxicology 2013, 56:261-265.
45. Vallone L., Boscariol D., Dragoni I. Aflatoxins in organic milk and diary products. Veterinary Research Communications 2006, 30(1):369-370.
46. Van Egmond H.P. Introduction. Mycotoxins in dairy products 1989, 1-10. Elsevier Applied Science, London and New York. H.P. Van Egmond (Ed.).
47. Aflatoxin M1 JECFA food additives series 47 2010, WHO, Available at, Accessed on 2012. http://www.inchem.org/documents/jecfa/jecmono/v47je%2002.htm.
48. Zinedine A., González-Osnaya L., Soriano J.M., Moltó J.C., Idrissi L., Mañes J. Presence of aflatoxin M1 in pasteurized milk from Morocco. International Journal of Food Microbiology 2007, 114:25-29.