메뉴 건너뛰기




Volumn 326, Issue 1-2, 2010, Pages 3-7

PRKAR1A and the evolution of pituitary tumors

Author keywords

Carney complex; Mouse models; Pituitary tumorigenesis; PRKAR1A; Protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; GROWTH HORMONE RELEASING FACTOR RECEPTOR; MESSENGER RNA; PROLACTIN; PROTEIN PRKAR1A; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 77955324701     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2010.04.027     Document Type: Review
Times cited : (41)

References (50)
  • 2
    • 0037178847 scopus 로고    scopus 로고
    • Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo
    • Amieux P.S., Howe D.G., Knickerbocker H., Lee D.C., Su T., Laszlo G.S., Idzerda R.L., McKnight G.S. Increased basal cAMP-dependent protein kinase activity inhibits the formation of mesoderm-derived structures in the developing mouse embryo. J. Biol. Chem. 2002, 277:27294-27304.
    • (2002) J. Biol. Chem. , vol.277 , pp. 27294-27304
    • Amieux, P.S.1    Howe, D.G.2    Knickerbocker, H.3    Lee, D.C.4    Su, T.5    Laszlo, G.S.6    Idzerda, R.L.7    McKnight, G.S.8
  • 4
    • 0035721572 scopus 로고    scopus 로고
    • Dopamine as a prolactin (PRL) inhibitor
    • Ben-Jonathan N., Hnasko R. Dopamine as a prolactin (PRL) inhibitor. Endocr. Rev. 2001, 22:724-763.
    • (2001) Endocr. Rev. , vol.22 , pp. 724-763
    • Ben-Jonathan, N.1    Hnasko, R.2
  • 9
    • 0026062347 scopus 로고
    • Pituitary hyperplasia and gigantism in mice caused by a cholera toxin transgene
    • Burton F.H., Hasel K.W., Bloom F.E., Sutcliffe J.G. Pituitary hyperplasia and gigantism in mice caused by a cholera toxin transgene. Nature 1991, 350:74-77.
    • (1991) Nature , vol.350 , pp. 74-77
    • Burton, F.H.1    Hasel, K.W.2    Bloom, F.E.3    Sutcliffe, J.G.4
  • 10
    • 58149212170 scopus 로고
    • Carney complex: the complex of myxomas, spotty pigmentation, endocrine overactivity, and schwannomas
    • Carney J.A. Carney complex: the complex of myxomas, spotty pigmentation, endocrine overactivity, and schwannomas. Semin. Dermatol. 1995, 14:90-98.
    • (1995) Semin. Dermatol. , vol.14 , pp. 90-98
    • Carney, J.A.1
  • 12
    • 59749104638 scopus 로고    scopus 로고
    • Mutations of the gene for the aryl hydrocarbon receptor-interacting protein in pituitary adenomas
    • Cazabat L., Guillaud-Bataille M., Bertherat J., Raffin-Sanson M.L. Mutations of the gene for the aryl hydrocarbon receptor-interacting protein in pituitary adenomas. Horm. Res. 2009, 71:132-141.
    • (2009) Horm. Res. , vol.71 , pp. 132-141
    • Cazabat, L.1    Guillaud-Bataille, M.2    Bertherat, J.3    Raffin-Sanson, M.L.4
  • 17
    • 0034864264 scopus 로고    scopus 로고
    • The effect of GHRH on somatotrope hyperplasia and tumor formation in the presence and absence of GH signaling
    • Kineman R.D., Teixeira L.T., Amargo G.V., Coschigano K.T., Kopchick J.J., Frohman L.A. The effect of GHRH on somatotrope hyperplasia and tumor formation in the presence and absence of GH signaling. Endocrinology 2001, 142:3764-3773.
    • (2001) Endocrinology , vol.142 , pp. 3764-3773
    • Kineman, R.D.1    Teixeira, L.T.2    Amargo, G.V.3    Coschigano, K.T.4    Kopchick, J.J.5    Frohman, L.A.6
  • 18
    • 0032715974 scopus 로고    scopus 로고
    • Genomic mapping of chromosomal region 2p15-p21 (D2S378-D2S391): integration of Genemap'98 within a framework of yeast and bacterial artificial chromosomes
    • Kirschner L.S., Taymans S.E., Pack S., Pak E., Pike B.L., Chandrasekharappa S.C., Zhuang Z., Stratakis C.A. Genomic mapping of chromosomal region 2p15-p21 (D2S378-D2S391): integration of Genemap'98 within a framework of yeast and bacterial artificial chromosomes. Genomics 1999, 62:21-33.
    • (1999) Genomics , vol.62 , pp. 21-33
    • Kirschner, L.S.1    Taymans, S.E.2    Pack, S.3    Pak, E.4    Pike, B.L.5    Chandrasekharappa, S.C.6    Zhuang, Z.7    Stratakis, C.A.8
  • 20
    • 0034642302 scopus 로고    scopus 로고
    • Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex
    • Kirschner L.S., Sandrini F., Monbo J., Lin J.P., Carney J.A., Stratakis C.A. Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex. Hum. Mol. Genet. 2000, 9:3037-3046.
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 3037-3046
    • Kirschner, L.S.1    Sandrini, F.2    Monbo, J.3    Lin, J.P.4    Carney, J.A.5    Stratakis, C.A.6
  • 24
    • 0033644144 scopus 로고    scopus 로고
    • Conditional gene knockout using cre recombinase
    • Le Y., Sauer B. Conditional gene knockout using cre recombinase. Methods Mol. Biol. 2000, 136:477-485.
    • (2000) Methods Mol. Biol. , vol.136 , pp. 477-485
    • Le, Y.1    Sauer, B.2
  • 25
    • 37249016342 scopus 로고    scopus 로고
    • Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality
    • Lin B.C., Sullivan R., Lee Y., Moran S., Glover E., Bradfield C.A. Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality. J. Biol. Chem. 2007, 282:35924-35932.
    • (2007) J. Biol. Chem. , vol.282 , pp. 35924-35932
    • Lin, B.C.1    Sullivan, R.2    Lee, Y.3    Moran, S.4    Glover, E.5    Bradfield, C.A.6
  • 26
    • 67649648242 scopus 로고    scopus 로고
    • Use of the metallothionein promoter-human growth hormone-releasing hormone (GHRH) mouse to identify regulatory pathways that suppress pituitary somatotrope hyperplasia and adenoma formation due to GHRH-receptor hyperactivation
    • Luque R.M., Soares B.S., Peng X.D., Krishnan S., Cordoba-Chacon J., Frohman L.A., Kineman R.D. Use of the metallothionein promoter-human growth hormone-releasing hormone (GHRH) mouse to identify regulatory pathways that suppress pituitary somatotrope hyperplasia and adenoma formation due to GHRH-receptor hyperactivation. Endocrinology 2009, 150:3177-3185.
    • (2009) Endocrinology , vol.150 , pp. 3177-3185
    • Luque, R.M.1    Soares, B.S.2    Peng, X.D.3    Krishnan, S.4    Cordoba-Chacon, J.5    Frohman, L.A.6    Kineman, R.D.7
  • 28
    • 0029121045 scopus 로고
    • Differential gene expression of growth hormone (GH)-releasing hormone (GRH) and GRH receptor in various rat tissues
    • Matsubara S., Sato M., Mizobuchi M., Niimi M., Takahara J. Differential gene expression of growth hormone (GH)-releasing hormone (GRH) and GRH receptor in various rat tissues. Endocrinology 1995, 136:4147-4150.
    • (1995) Endocrinology , vol.136 , pp. 4147-4150
    • Matsubara, S.1    Sato, M.2    Mizobuchi, M.3    Niimi, M.4    Takahara, J.5
  • 30
    • 28544445921 scopus 로고    scopus 로고
    • Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins
    • Nadella K.S., Kirschner L.S. Disruption of protein kinase a regulation causes immortalization and dysregulation of D-type cyclins. Cancer Res. 2005, 65:10307-10315.
    • (2005) Cancer Res. , vol.65 , pp. 10307-10315
    • Nadella, K.S.1    Kirschner, L.S.2
  • 32
    • 0033767048 scopus 로고    scopus 로고
    • Genetic and histologic studies of somatomammotropic pituitary tumors in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex)
    • Pack S.D., Kirschner L.S., Pak E., Zhuang Z., Carney J.A., Stratakis C.A. Genetic and histologic studies of somatomammotropic pituitary tumors in patients with the "complex of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex). J. Clin. Endocrinol. Metab. 2000, 85:3860-3865.
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 3860-3865
    • Pack, S.D.1    Kirschner, L.S.2    Pak, E.3    Zhuang, Z.4    Carney, J.A.5    Stratakis, C.A.6
  • 34
    • 38749151856 scopus 로고    scopus 로고
    • Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A
    • Pavel E., Nadella K., Towns W.H., Kirschner L.S. Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A. Mol. Endocrinol. 2008, 22:430-440.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 430-440
    • Pavel, E.1    Nadella, K.2    Towns, W.H.3    Kirschner, L.S.4
  • 35
    • 0034087332 scopus 로고    scopus 로고
    • Prolactin secretion abnormalities in patients with the "syndrome of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex)
    • Raff S.B., Carney J.A., Krugman D., Doppman J.L., Stratakis C.A. Prolactin secretion abnormalities in patients with the "syndrome of spotty skin pigmentation, myxomas, endocrine overactivity and schwannomas" (Carney complex). J. Pediatr. Endocrinol. Metab. 2000, 13:373-379.
    • (2000) J. Pediatr. Endocrinol. Metab. , vol.13 , pp. 373-379
    • Raff, S.B.1    Carney, J.A.2    Krugman, D.3    Doppman, J.L.4    Stratakis, C.A.5
  • 38
    • 0030049026 scopus 로고    scopus 로고
    • Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2
    • Stratakis C.A., Carney J.A., Lin J.P., Papanicolaou D.A., Karl M., Kastner D.L., Pras E., Chrousos G.P. Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2. J. Clin. Invest. 1996, 97:699-705.
    • (1996) J. Clin. Invest. , vol.97 , pp. 699-705
    • Stratakis, C.A.1    Carney, J.A.2    Lin, J.P.3    Papanicolaou, D.A.4    Karl, M.5    Kastner, D.L.6    Pras, E.7    Chrousos, G.P.8
  • 39
    • 0034853288 scopus 로고    scopus 로고
    • Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation
    • Stratakis C.A., Kirschner L.S., Carney J.A. Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation. J. Clin. Endocrinol. Metab. 2001, 86:4041-4046.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 4041-4046
    • Stratakis, C.A.1    Kirschner, L.S.2    Carney, J.A.3
  • 40
    • 0038025925 scopus 로고    scopus 로고
    • Thyrotropin-releasing hormone receptors-similarities and differences
    • Sun Y., Lu X., Gershengorn M.C. Thyrotropin-releasing hormone receptors-similarities and differences. J. Mol. Endocrinol. 2003, 30:87-97.
    • (2003) J. Mol. Endocrinol. , vol.30 , pp. 87-97
    • Sun, Y.1    Lu, X.2    Gershengorn, M.C.3
  • 41
    • 0034611474 scopus 로고    scopus 로고
    • P27Kip1-deficient mice exhibit accelerated growth hormone-releasing hormone (GHRH)-induced somatotrope proliferation and adenoma formation
    • Teixeira L.T., Kiyokawa H., Peng X.D., Christov K.T., Frohman L.A., Kineman R.D. p27Kip1-deficient mice exhibit accelerated growth hormone-releasing hormone (GHRH)-induced somatotrope proliferation and adenoma formation. Oncogene 2000, 19:1875-1884.
    • (2000) Oncogene , vol.19 , pp. 1875-1884
    • Teixeira, L.T.1    Kiyokawa, H.2    Peng, X.D.3    Christov, K.T.4    Frohman, L.A.5    Kineman, R.D.6
  • 45
    • 0034793851 scopus 로고    scopus 로고
    • Endocrine manifestations of stimulatory G protein alpha-subunit mutations and the role of genomic imprinting
    • Weinstein L.S., Yu S., Warner D.R., Liu J. Endocrine manifestations of stimulatory G protein alpha-subunit mutations and the role of genomic imprinting. Endocr. Rev. 2001, 22:675-705.
    • (2001) Endocr. Rev. , vol.22 , pp. 675-705
    • Weinstein, L.S.1    Yu, S.2    Warner, D.R.3    Liu, J.4
  • 46
    • 21344466760 scopus 로고    scopus 로고
    • Clinical phenotypes and molecular genetic mechanisms of Carney complex
    • Wilkes D., McDermott D.A., Basson C.T. Clinical phenotypes and molecular genetic mechanisms of Carney complex. Lancet Oncol. 2005, 6:501-508.
    • (2005) Lancet Oncol. , vol.6 , pp. 501-508
    • Wilkes, D.1    McDermott, D.A.2    Basson, C.T.3
  • 48
    • 40949119860 scopus 로고    scopus 로고
    • Development of a pituitary-specific cre line targeted to the Pit-1 lineage
    • Yin Z., Williams-Simons L., Rawahneh L., Asa S., Kirschner L.S. Development of a pituitary-specific cre line targeted to the Pit-1 lineage. Genesis 2008, 46:37-42.
    • (2008) Genesis , vol.46 , pp. 37-42
    • Yin, Z.1    Williams-Simons, L.2    Rawahneh, L.3    Asa, S.4    Kirschner, L.S.5
  • 49
    • 38749106141 scopus 로고    scopus 로고
    • Pituitary-specific knockout of the Carney complex gene Prkar1a leads to pituitary tumorigenesis
    • Yin Z., Williams-Simons L., Parlow A.F., Asa S., Kirschner L.S. Pituitary-specific knockout of the Carney complex gene Prkar1a leads to pituitary tumorigenesis. Mol. Endocrinol. 2008, 22:380-387.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 380-387
    • Yin, Z.1    Williams-Simons, L.2    Parlow, A.F.3    Asa, S.4    Kirschner, L.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.