메뉴 건너뛰기




Volumn 10, Issue 1, 2013, Pages

Surface coatings of ZnO nanoparticles mitigate differentially a host of transcriptional, protein and signalling responses in primary human olfactory cells

Author keywords

Cell signalling; DNA damage; Gene expression; Nanoparticle; Olfactory; Zinc oxide

Indexed keywords

CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; NANOPARTICLE; UNCLASSIFIED DRUG; ZINC OXIDE; ZINC OXIDE NANOPARTICLE;

EID: 84886168023     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-10-54     Document Type: Article
Times cited : (34)

References (60)
  • 1
    • 3042817115 scopus 로고    scopus 로고
    • Zinc oxide nanostructures: growth, properties and applications
    • Wang ZL. Zinc oxide nanostructures: growth, properties and applications. J Phys Condens Matter 2004, 16:R829-R858.
    • (2004) J Phys Condens Matter , vol.16
    • Wang, Z.L.1
  • 2
    • 0033051439 scopus 로고    scopus 로고
    • Microfine zinc oxide (z-cote) as a photostable UVA/UVB sunblock agent
    • 10.1016/S0190-9622(99)70532-3, 9922017
    • Mitchnick MA, Fairhurst D, Pinnell SR. Microfine zinc oxide (z-cote) as a photostable UVA/UVB sunblock agent. J Am Acad Dermatol 1999, 40:85-90. 10.1016/S0190-9622(99)70532-3, 9922017.
    • (1999) J Am Acad Dermatol , vol.40 , pp. 85-90
    • Mitchnick, M.A.1    Fairhurst, D.2    Pinnell, S.R.3
  • 3
    • 0034849205 scopus 로고    scopus 로고
    • Sunscreens
    • 10.1016/S0738-081X(01)00190-0, 11535388
    • Wolf R, Wolf D, Morganti P, Ruocco V. Sunscreens. Clin Dermatol 2001, 19:452-459. 10.1016/S0738-081X(01)00190-0, 11535388.
    • (2001) Clin Dermatol , vol.19 , pp. 452-459
    • Wolf, R.1    Wolf, D.2    Morganti, P.3    Ruocco, V.4
  • 4
    • 77749308361 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles in modern sunscreens: an analysis of potential exposure and hazard
    • Osmond MJ, McCall MJ. Zinc oxide nanoparticles in modern sunscreens: an analysis of potential exposure and hazard. Nanotox 2010, 4:15-41.
    • (2010) Nanotox , vol.4 , pp. 15-41
    • Osmond, M.J.1    McCall, M.J.2
  • 5
    • 0033835509 scopus 로고    scopus 로고
    • Inorganic dust pneumonias: the metal-related parenchymal disorders
    • Kelleher P, Pacheco K, Newman L. Inorganic dust pneumonias: the metal-related parenchymal disorders. Environ Health Perspect 2000, 108:685-696.
    • (2000) Environ Health Perspect , vol.108 , pp. 685-696
    • Kelleher, P.1    Pacheco, K.2    Newman, L.3
  • 6
    • 84862925782 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity
    • Kao Y-Y, Chen Y-C, Cheng T-J, Chiung Y-M, Liu P-S. Zinc oxide nanoparticles interfere with zinc ion homeostasis to cause cytotoxicity. Tox Sci 2012, 125:462-472.
    • (2012) Tox Sci , vol.125 , pp. 462-472
    • Kao, Y.-Y.1    Chen, Y.-C.2    Cheng, T.-J.3    Chiung, Y.-M.4    Liu, P.-S.5
  • 7
    • 80052562186 scopus 로고    scopus 로고
    • Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes
    • 10.1186/1743-8977-8-27, 3179432, 21896169
    • Cho W-S, Duffin R, Howie S, Scotton C, Wallace W, MacNee W, Bradley M, Megson I, Donaldson K. Progressive severe lung injury by zinc oxide nanoparticles; the role of Zn2+ dissolution inside lysosomes. Part Fibre Toxicol 2011, 8:27. 10.1186/1743-8977-8-27, 3179432, 21896169.
    • (2011) Part Fibre Toxicol , vol.8 , pp. 27
    • Cho, W.-S.1    Duffin, R.2    Howie, S.3    Scotton, C.4    Wallace, W.5    MacNee, W.6    Bradley, M.7    Megson, I.8    Donaldson, K.9
  • 8
    • 84855878885 scopus 로고    scopus 로고
    • Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs
    • Cho W-S, Duffin R, Poland C, Duschl A, Oostingh GJ, MacNee W, Bradley M, Megson I, Donaldson K. Differential pro-inflammatory effects of metal oxide nanoparticles and their soluble ions in vitro and in vivo; zinc and copper nanoparticles, but not their ions, recruit eosinophils to the lungs. Nanotox 2012, 6:22-35.
    • (2012) Nanotox , vol.6 , pp. 22-35
    • Cho, W.-S.1    Duffin, R.2    Poland, C.3    Duschl, A.4    Oostingh, G.J.5    MacNee, W.6    Bradley, M.7    Megson, I.8    Donaldson, K.9
  • 9
    • 84866045532 scopus 로고    scopus 로고
    • A review of mammalian toxicity of ZnO nanoparticles
    • Vandebriel R, Jong WD. A review of mammalian toxicity of ZnO nanoparticles. Nanotech Sci App 2012, 5:61-71.
    • (2012) Nanotech Sci App , vol.5 , pp. 61-71
    • Vandebriel, R.1    Jong, W.D.2
  • 10
    • 34147158989 scopus 로고    scopus 로고
    • Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: Effect of particle composition
    • 10.1289/ehp.115-a403, 1849911, 17431490
    • Gojova A, Guo B, Kota RS, Rutledge JC, Kennedy IM, Barakat AI. Induction of inflammation in vascular endothelial cells by metal oxide nanoparticles: Effect of particle composition. Environ Health Perspect 2007, 115:403-409. 10.1289/ehp.115-a403, 1849911, 17431490.
    • (2007) Environ Health Perspect , vol.115 , pp. 403-409
    • Gojova, A.1    Guo, B.2    Kota, R.S.3    Rutledge, J.C.4    Kennedy, I.M.5    Barakat, A.I.6
  • 11
    • 69249190460 scopus 로고    scopus 로고
    • Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibrosis
    • Lai JCK, Lai MB, Jandhyam S, Dukhande VV, Bhushan A, Daniels CK, Leung SW. Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibrosis. Internat J Nanomed 2008, 3:533-545.
    • (2008) Internat J Nanomed , vol.3 , pp. 533-545
    • Lai, J.C.K.1    Lai, M.B.2    Jandhyam, S.3    Dukhande, V.V.4    Bhushan, A.5    Daniels, C.K.6    Leung, S.W.7
  • 12
    • 56049106549 scopus 로고    scopus 로고
    • Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties
    • 10.1021/nn800511k, 19206459
    • Xia T, Kovochich M, Liong M, Madler L, Gilbert B, Shi H, Yeh JI, Zink JI, Nel AE. Comparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress properties. ACS Nano 2008, 2:2121-2134. 10.1021/nn800511k, 19206459.
    • (2008) ACS Nano , vol.2 , pp. 2121-2134
    • Xia, T.1    Kovochich, M.2    Liong, M.3    Madler, L.4    Gilbert, B.5    Shi, H.6    Yeh, J.I.7    Zink, J.I.8    Nel, A.E.9
  • 13
    • 65449153593 scopus 로고    scopus 로고
    • Nanosized zinc oxide particles induce neural stem cell apopotosis
    • 10.1088/0957-4484/20/11/115101, 19420431
    • Deng X, Luan Q, Chen W, Wang Y, Wu M, Zhang H, Jiao Z. Nanosized zinc oxide particles induce neural stem cell apopotosis. Nanotechnology 2009, 20:115101. 10.1088/0957-4484/20/11/115101, 19420431.
    • (2009) Nanotechnology , vol.20 , pp. 115101
    • Deng, X.1    Luan, Q.2    Chen, W.3    Wang, Y.4    Wu, M.5    Zhang, H.6    Jiao, Z.7
  • 14
    • 33751192451 scopus 로고    scopus 로고
    • Toxicity of metal oxide nanoparticles in mammalian cells
    • Jeng H, Swanson J. Toxicity of metal oxide nanoparticles in mammalian cells. J Environ Sci Health A 2006, 41:2699-2711.
    • (2006) J Environ Sci Health A , vol.41 , pp. 2699-2711
    • Jeng, H.1    Swanson, J.2
  • 15
    • 0031260302 scopus 로고    scopus 로고
    • Early pulmonary cytokine responses to zinc oxide fume inhalation
    • 10.1006/enrs.1997.3765, 9356189
    • Kuschner WG, D'Alessandro A, Wong H, Blanc PD. Early pulmonary cytokine responses to zinc oxide fume inhalation. Environ Res 1997, 75:7-11. 10.1006/enrs.1997.3765, 9356189.
    • (1997) Environ Res , vol.75 , pp. 7-11
    • Kuschner, W.G.1    D'Alessandro, A.2    Wong, H.3    Blanc, P.D.4
  • 16
    • 0026659429 scopus 로고
    • Pulmonary effects of inhaled zinc oxide in human subjects, guinea pigs, rats, and rabbits
    • 10.1080/15298669291360030, 1509990
    • Gordon T, Chen LC, Fine JM, Schlesinger RB, Su WY, Kimmel TA, Madur MO. Pulmonary effects of inhaled zinc oxide in human subjects, guinea pigs, rats, and rabbits. Am Ind Hyg Assoc J 1992, 53:503-509. 10.1080/15298669291360030, 1509990.
    • (1992) Am Ind Hyg Assoc J , vol.53 , pp. 503-509
    • Gordon, T.1    Chen, L.C.2    Fine, J.M.3    Schlesinger, R.B.4    Su, W.Y.5    Kimmel, T.A.6    Madur, M.O.7
  • 17
    • 0030848962 scopus 로고    scopus 로고
    • Metal fume fever: characterization of clinical and plasma IL-6 responses in controlled human exposures to zinc oxide fume at and below the threshold limit value
    • 10.1097/00043764-199708000-00006, 9273875
    • Fine JM, Gordon T, Chen LC, Kinney P, Falcone G, Beckett W. Metal fume fever: characterization of clinical and plasma IL-6 responses in controlled human exposures to zinc oxide fume at and below the threshold limit value. J Occup Environ Med 1997, 39:722-726. 10.1097/00043764-199708000-00006, 9273875.
    • (1997) J Occup Environ Med , vol.39 , pp. 722-726
    • Fine, J.M.1    Gordon, T.2    Chen, L.C.3    Kinney, P.4    Falcone, G.5    Beckett, W.6
  • 18
    • 0033741633 scopus 로고    scopus 로고
    • Characterization of clinical tolerance to inhaled zinc oxide in naive subjects and sheet metal workers
    • 10.1097/00043764-200011000-00010, 11094787
    • Fine JM, Gordon T, Chen LC, Kinney P, Falcone G, Sparer J, Beckett WS. Characterization of clinical tolerance to inhaled zinc oxide in naive subjects and sheet metal workers. J Occup Environ Med 2000, 42:1085-1091. 10.1097/00043764-200011000-00010, 11094787.
    • (2000) J Occup Environ Med , vol.42 , pp. 1085-1091
    • Fine, J.M.1    Gordon, T.2    Chen, L.C.3    Kinney, P.4    Falcone, G.5    Sparer, J.6    Beckett, W.S.7
  • 19
    • 84859637265 scopus 로고    scopus 로고
    • Photoprotection in the era of nanotechnology
    • 10.1016/j.sder.2011.07.006, 22123418
    • Wang S, Tooley I. Photoprotection in the era of nanotechnology. Semin Cutan Med Surg 2011, 30:210-213. 10.1016/j.sder.2011.07.006, 22123418.
    • (2011) Semin Cutan Med Surg , vol.30 , pp. 210-213
    • Wang, S.1    Tooley, I.2
  • 20
    • 79952111055 scopus 로고    scopus 로고
    • Effects of surface chemistry on cytotoxicity, genotoxicity, and the generation of reactive oxygen species induced by ZnO nanoparticles
    • 10.1021/la101033n, 20809599
    • Yin H, Casey PS, McCall MJ, Fenech M. Effects of surface chemistry on cytotoxicity, genotoxicity, and the generation of reactive oxygen species induced by ZnO nanoparticles. Langmuir 2010, 26:15399-15408. 10.1021/la101033n, 20809599.
    • (2010) Langmuir , vol.26 , pp. 15399-15408
    • Yin, H.1    Casey, P.S.2    McCall, M.J.3    Fenech, M.4
  • 21
    • 79952111387 scopus 로고    scopus 로고
    • Surface modifications of ZnO nanoparticles and their cytotoxicity
    • 10.1166/jnn.2010.2833, 21137983
    • Yin H, Casey P, McCall M. Surface modifications of ZnO nanoparticles and their cytotoxicity. J Nanosci Nanotechnol 2010, 10:7565-7570. 10.1166/jnn.2010.2833, 21137983.
    • (2010) J Nanosci Nanotechnol , vol.10 , pp. 7565-7570
    • Yin, H.1    Casey, P.2    McCall, M.3
  • 23
  • 25
    • 77953417519 scopus 로고    scopus 로고
    • Chapter 8: Nanoparticles: transport across the olfactory epithelium and application to the assessment of brain function in health and disease
    • Aschner M. Chapter 8: Nanoparticles: transport across the olfactory epithelium and application to the assessment of brain function in health and disease. Prog Brain Res 2009, 180:141-152.
    • (2009) Prog Brain Res , vol.180 , pp. 141-152
    • Aschner, M.1
  • 27
    • 77953916083 scopus 로고    scopus 로고
    • Potential of nanoparticulate drug delivery systems by intranasal administration
    • 10.2174/138161210791164108, 20210751
    • Ali J, Ali M, Baboota S, Sahni J, Ramassamy C, Dao L, Bhavna. Potential of nanoparticulate drug delivery systems by intranasal administration. Curr Pharm Des 2010, 16:1644-1653. 10.2174/138161210791164108, 20210751.
    • (2010) Curr Pharm Des , vol.16 , pp. 1644-1653
    • Ali, J.1    Ali, M.2    Baboota, S.3    Sahni, J.4    Ramassamy, C.5    Dao, L.6    Bhavna7
  • 32
    • 84864258079 scopus 로고    scopus 로고
    • The effect of nanoparticle size, shape, and surface chemistry on biological systems
    • 10.1146/annurev-bioeng-071811-150124, 22524388
    • Albanese A, Tang S, Chan W. The effect of nanoparticle size, shape, and surface chemistry on biological systems. Annu Rev Biomed Eng 2012, 14:1-16. 10.1146/annurev-bioeng-071811-150124, 22524388.
    • (2012) Annu Rev Biomed Eng , vol.14 , pp. 1-16
    • Albanese, A.1    Tang, S.2    Chan, W.3
  • 33
    • 84867487858 scopus 로고    scopus 로고
    • Independent cytotoxic and inflammatory responses to zinc oxide nanoparticles in human monocytes and macrophages
    • Feltis B, OKeefe S, Harford A, Piva T, Turney T, Wright P. Independent cytotoxic and inflammatory responses to zinc oxide nanoparticles in human monocytes and macrophages. Nanotox 2011, 6:757-765.
    • (2011) Nanotox , vol.6 , pp. 757-765
    • Feltis, B.1    OKeefe, S.2    Harford, A.3    Piva, T.4    Turney, T.5    Wright, P.6
  • 34
    • 0036083469 scopus 로고    scopus 로고
    • New ideas about aldosterone signaling in epithelia
    • Stockand J. New ideas about aldosterone signaling in epithelia. Am J Physiol Renal Physiol 2002, 282:F559-F576.
    • (2002) Am J Physiol Renal Physiol , vol.282
    • Stockand, J.1
  • 35
    • 47849083585 scopus 로고    scopus 로고
    • Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults
    • 10.1016/j.mrrev.2007.11.006, 2585047, 18164232
    • Osburn W, Kensler T. Nrf2 signaling: an adaptive response pathway for protection against environmental toxic insults. Mutat Res 2008, 659:31-39. 10.1016/j.mrrev.2007.11.006, 2585047, 18164232.
    • (2008) Mutat Res , vol.659 , pp. 31-39
    • Osburn, W.1    Kensler, T.2
  • 36
    • 84886793528 scopus 로고    scopus 로고
    • A Comparative Study of Physico-Chemical Properties of Commercial, Ultrafine ZnO Particles from Different Batches
    • Helsinki, Finland, Abstract available in SENN2012 Programme and Abstracts, p47, at
    • Yin H, Casey P, Coleman V, Moghaddam M, McCall M. A Comparative Study of Physico-Chemical Properties of Commercial, Ultrafine ZnO Particles from Different Batches. International Congress on Safety of Engineered Nanoparticles and Nanotechnologies 2012, Helsinki, Finland, Abstract available in SENN2012 Programme and Abstracts, p47, at http://www.ttl.fi/en/publications/Electronic_publications/Pages/SENN2012.aspx.
    • (2012) International Congress on Safety of Engineered Nanoparticles and Nanotechnologies
    • Yin, H.1    Casey, P.2    Coleman, V.3    Moghaddam, M.4    McCall, M.5
  • 37
    • 67349241298 scopus 로고    scopus 로고
    • Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cells
    • 10.1016/j.tiv.2009.03.003, 19306923
    • Pavlica S, Gaunitz F, Gebhardt R. Comparative in vitro toxicity of seven zinc-salts towards neuronal PC12 cells. Toxicol In Vitro 2009, 23:653-659. 10.1016/j.tiv.2009.03.003, 19306923.
    • (2009) Toxicol In Vitro , vol.23 , pp. 653-659
    • Pavlica, S.1    Gaunitz, F.2    Gebhardt, R.3
  • 38
    • 84867548417 scopus 로고    scopus 로고
    • Formation of zinc-containing nanoparticles from Zn2+ ions in cell culture media: Implications for the nanotoxicology of ZnO
    • 10.1021/tx300241q, 22978249
    • Turney T, Duriska M, Jayaratne V, Elbaz A, O'Keefe S, Hastings A, Piva T, Wright P, Feltis B. Formation of zinc-containing nanoparticles from Zn2+ ions in cell culture media: Implications for the nanotoxicology of ZnO. Chem Res Toxicol 2012, 25:2057-2066. 10.1021/tx300241q, 22978249.
    • (2012) Chem Res Toxicol , vol.25 , pp. 2057-2066
    • Turney, T.1    Duriska, M.2    Jayaratne, V.3    Elbaz, A.4    O'Keefe, S.5    Hastings, A.6    Piva, T.7    Wright, P.8    Feltis, B.9
  • 39
    • 77951230643 scopus 로고    scopus 로고
    • ZnO particulate matter requires cell contact for toxicity in human colon cancer cells
    • 10.1021/tx900203v, 20155942
    • Moos P, Chung K, Woessner D, Honeggar M, Cutler N, Veranth J. ZnO particulate matter requires cell contact for toxicity in human colon cancer cells. Chem Res Toxicol 2010, 23:733-739. 10.1021/tx900203v, 20155942.
    • (2010) Chem Res Toxicol , vol.23 , pp. 733-739
    • Moos, P.1    Chung, K.2    Woessner, D.3    Honeggar, M.4    Cutler, N.5    Veranth, J.6
  • 40
    • 78651411858 scopus 로고    scopus 로고
    • Differential gene expression in Daphnia magna suggests distinct modes of action and bioavailability for ZnO nanoparticles and Zn ions
    • 10.1021/es102501z, 21142172
    • Poynton H, Lazorchak J, Impellitteri C, Smith M, Rogers K, Patra M, Hammer K, Allen H, Vulpe C. Differential gene expression in Daphnia magna suggests distinct modes of action and bioavailability for ZnO nanoparticles and Zn ions. Environ Sci Technol 2011, 45:762-768. 10.1021/es102501z, 21142172.
    • (2011) Environ Sci Technol , vol.45 , pp. 762-768
    • Poynton, H.1    Lazorchak, J.2    Impellitteri, C.3    Smith, M.4    Rogers, K.5    Patra, M.6    Hammer, K.7    Allen, H.8    Vulpe, C.9
  • 41
    • 84865129488 scopus 로고    scopus 로고
    • Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2)
    • 10.1007/s10495-012-0705-6, 22395444
    • Sharma V, Anderson D, Dhawan A. Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2). Apoptosis 2012, 17:852-870. 10.1007/s10495-012-0705-6, 22395444.
    • (2012) Apoptosis , vol.17 , pp. 852-870
    • Sharma, V.1    Anderson, D.2    Dhawan, A.3
  • 42
    • 68149136657 scopus 로고    scopus 로고
    • Cellular responses to endoplasmic reticulum stress and apoptosis
    • 10.1007/s10495-009-0341-y, 19360473
    • Rasheva V, Domingos P. Cellular responses to endoplasmic reticulum stress and apoptosis. Apoptosis 2009, 14:996-1007. 10.1007/s10495-009-0341-y, 19360473.
    • (2009) Apoptosis , vol.14 , pp. 996-1007
    • Rasheva, V.1    Domingos, P.2
  • 44
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • 10.1016/S0092-8674(00)80416-X, 9363941
    • Shieh S-Y, Ikeda M, Taya Y, Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 1997, 91:325-334. 10.1016/S0092-8674(00)80416-X, 9363941.
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.-Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 45
    • 80052366948 scopus 로고    scopus 로고
    • The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles
    • 10.1016/j.biomaterials.2011.07.036, 21807406
    • Ng K, Khoo S, Heng B, Setyawati M, Tan E, Zhao X, Xiong S, Fang W, Leong D, Loo J. The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles. Biomaterials 2011, 32:8218-8225. 10.1016/j.biomaterials.2011.07.036, 21807406.
    • (2011) Biomaterials , vol.32 , pp. 8218-8225
    • Ng, K.1    Khoo, S.2    Heng, B.3    Setyawati, M.4    Tan, E.5    Zhao, X.6    Xiong, S.7    Fang, W.8    Leong, D.9    Loo, J.10
  • 46
    • 82655173857 scopus 로고    scopus 로고
    • ZnO nanoparticles induce apoptosis in human dermal fibroblasts via p53 and p38 pathways
    • 10.1016/j.tiv.2011.08.011, 21903158
    • Meyer K, Rajanahalli P, Ahamed M, Rowe J, Hong Y. ZnO nanoparticles induce apoptosis in human dermal fibroblasts via p53 and p38 pathways. Toxicol In Vitro 2011, 25:1721-1726. 10.1016/j.tiv.2011.08.011, 21903158.
    • (2011) Toxicol In Vitro , vol.25 , pp. 1721-1726
    • Meyer, K.1    Rajanahalli, P.2    Ahamed, M.3    Rowe, J.4    Hong, Y.5
  • 47
    • 77952981537 scopus 로고    scopus 로고
    • DNA polymerase eta, a key protein in translesion synthesis in human cells
    • 10.1007/978-90-481-3471-7_10, 20012583
    • Cruet-Hennequart S, Gallagher K, Sokòl A, Villalan S, Prendergast A, Carty M. DNA polymerase eta, a key protein in translesion synthesis in human cells. Subcell Biochem 2010, 50:189-209. 10.1007/978-90-481-3471-7_10, 20012583.
    • (2010) Subcell Biochem , vol.50 , pp. 189-209
    • Cruet-Hennequart, S.1    Gallagher, K.2    Sokòl, A.3    Villalan, S.4    Prendergast, A.5    Carty, M.6
  • 48
    • 78149303282 scopus 로고    scopus 로고
    • Genotoxicity and cytotoxicity of zinc oxide and titanium dioxide in HEp-2 cells
    • 10.2217/nnm.10.52, 21039197
    • Osman I, Baumgartner A, Cemeli E, Fletcher J, Anderson D. Genotoxicity and cytotoxicity of zinc oxide and titanium dioxide in HEp-2 cells. Nanomedicine 2010, 5:1193-1203. 10.2217/nnm.10.52, 21039197.
    • (2010) Nanomedicine , vol.5 , pp. 1193-1203
    • Osman, I.1    Baumgartner, A.2    Cemeli, E.3    Fletcher, J.4    Anderson, D.5
  • 50
    • 84874636635 scopus 로고    scopus 로고
    • Inflammatory and oxidative stress responses of an alveolar epithelial cell line to airborne zinc oxide nanoparticles at the air-liquid interface: a comparison with conventional, submerged cell-culture conditions
    • 3581099, 23484138
    • Lenz A-G, Karg E, Brendel E, Hinze-Heyn H, Maier K, Eickelberg O, Stoeger T, Schmid O. Inflammatory and oxidative stress responses of an alveolar epithelial cell line to airborne zinc oxide nanoparticles at the air-liquid interface: a comparison with conventional, submerged cell-culture conditions. Biomed Res Int 2013, 2013:652632. 3581099, 23484138.
    • (2013) Biomed Res Int , vol.2013 , pp. 652632
    • Lenz, A.-G.1    Karg, E.2    Brendel, E.3    Hinze-Heyn, H.4    Maier, K.5    Eickelberg, O.6    Stoeger, T.7    Schmid, O.8
  • 51
    • 84874522482 scopus 로고    scopus 로고
    • Effects of flame made zinc oxide particles in human lung cells - a comparison of aerosol and suspension exposures
    • 10.1186/1743-8977-9-33, 3585858, 22901679
    • Raemy D, Grass R, Stark W, Schumacher C, Clift M, Gehr P, Rothen-Rutishauser B. Effects of flame made zinc oxide particles in human lung cells - a comparison of aerosol and suspension exposures. Part Fibre Toxicol 2012, 9:33. 10.1186/1743-8977-9-33, 3585858, 22901679.
    • (2012) Part Fibre Toxicol , vol.9 , pp. 33
    • Raemy, D.1    Grass, R.2    Stark, W.3    Schumacher, C.4    Clift, M.5    Gehr, P.6    Rothen-Rutishauser, B.7
  • 52
    • 75349091411 scopus 로고    scopus 로고
    • Deposition of inhaled nanoparticles in the rat nasal passages: dose to the olfactory region
    • 10.3109/08958370902882713, 19831956
    • Guilherme J, Kimbell J. Deposition of inhaled nanoparticles in the rat nasal passages: dose to the olfactory region. Inhal Toxicol 2009, 21:1165-1175. 10.3109/08958370902882713, 19831956.
    • (2009) Inhal Toxicol , vol.21 , pp. 1165-1175
    • Guilherme, J.1    Kimbell, J.2
  • 54
    • 12444272525 scopus 로고
    • Adsorption of gases in multimolecular layers
    • Brunauer S, Emmett PH, Teller E. Adsorption of gases in multimolecular layers. J Am Chem Soc 1938, 60:309-319.
    • (1938) J Am Chem Soc , vol.60 , pp. 309-319
    • Brunauer, S.1    Emmett, P.H.2    Teller, E.3
  • 55
    • 77953356208 scopus 로고    scopus 로고
    • Development of cell-based assays for cytokine receptor signaling, using an AlphaScreen SureFire assay format
    • 10.1016/j.ab.2010.04.007, 20382104
    • Osmond RIW, Das S, Crouch MF. Development of cell-based assays for cytokine receptor signaling, using an AlphaScreen SureFire assay format. Anal Biochem 2010, 403:94-101. 10.1016/j.ab.2010.04.007, 20382104.
    • (2010) Anal Biochem , vol.403 , pp. 94-101
    • Osmond, R.I.W.1    Das, S.2    Crouch, M.F.3
  • 58
    • 84886771942 scopus 로고    scopus 로고
    • Risk-conscious correction of batch artefacts and multiplicity: Maximising information extraction from high-throughput gene-expression datasets
    • Melbourne
    • Oytam Y. Risk-conscious correction of batch artefacts and multiplicity: Maximising information extraction from high-throughput gene-expression datasets. Bioinformatics Focus on Analytical Methods 2012, Melbourne.
    • (2012) Bioinformatics Focus on Analytical Methods
    • Oytam, Y.1
  • 59
    • 84886781569 scopus 로고    scopus 로고
    • A signals and systems approach to quantifying false discovery rates which is robust against batch noise in throughput genomic datasets
    • Sydney
    • Oytam Y. A signals and systems approach to quantifying false discovery rates which is robust against batch noise in throughput genomic datasets. Human Genome Meeting, Genetics and Genomics in Personalised Medicine 2012, Sydney.
    • (2012) Human Genome Meeting, Genetics and Genomics in Personalised Medicine
    • Oytam, Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.