The role of the tumor suppressor p53 pathway in the cellular DNA damage response to zinc oxide nanoparticles

Biomaterials

Volumn 32, Issue 32, 2011, Pages 8218-8225

  Ng, Kee Woei ^a   Khoo, Stella P K ^b   Heng, Boon Chin ^a   Setyawati, Magdiel I ^c   Tan, Eng Chok ^b   Zhao, Xinxin ^a   Xiong, Sijing ^a   Fang, Wanru ^d   Leong, David T ^c,d   Loo, Joachim S C ^a  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

DNA damage; Genotoxicology; Nanoparticles; Nanotoxicology; P53; Zinc oxide

Indexed keywords

CELL NUMBER; CELL TOXICITY; CELL-CYCLE PROGRESSION; CELLULAR DNA DAMAGE; CELLULAR RESPONSE; CONCOMITANT DECREASE; DNA DAMAGES; GENOTOXICOLOGY; NANOTOXICOLOGY; P53; PROGRAMMED CELL DEATHS; TARGET CELLS; TUMOR SUPPRESSORS; ZINC OXIDE NANOPARTICLES; ZNO NANOPARTICLES;

CELL CULTURE; CELL DEATH; DNA; PATHOLOGY; TUMORS; ZINC; ZINC OXIDE;

NANOPARTICLES;

CELL DNA; NANOPARTICLE; PROTEIN P53; SHORT HAIRPIN RNA; ZINC OXIDE;

APOPTOSIS; ARTICLE; CELL COUNT; CELL CYCLE PROGRESSION; CONTROLLED STUDY; DNA DAMAGE; GENE SILENCING; HUMAN; HUMAN CELL; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; SKIN FIBROBLAST;

ANIMALS; CELL DEATH; CELL LINE; DNA DAMAGE; HUMANS; MICE; MODELS, BIOLOGICAL; MUTAGENS; NANOPARTICLES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; ZINC OXIDE;

EID: 80052366948     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.07.036     Document Type: Article

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