-
1
-
-
0035408611
-
Cytokines: past, present, and future
-
Oppenheim JJ. (2001) Cytokines: past, present, and future. Int. J. Hematol. 74, 3-8.
-
(2001)
Int. J. Hematol.
, vol.74
, pp. 3-8
-
-
Oppenheim, J.J.1
-
2
-
-
0023773031
-
Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha
-
Buchan G, Barrett K, Turner M, Chantry D, Maini RN, Feldmann M. (1988) Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha. Clin. Exp. Immunol. 73, 449-455.
-
(1988)
Clin. Exp. Immunol.
, vol.73
, pp. 449-455
-
-
Buchan, G.1
Barrett, K.2
Turner, M.3
Chantry, D.4
Maini, R.N.5
Feldmann, M.6
-
3
-
-
0026501809
-
In situ hybridization of IL-6 in rheumatoid arthritis
-
Wood NC, Symons JA, Dickens E, Duff GW. (1992) In situ hybridization of IL-6 in rheumatoid arthritis. Clin. Exp. Immunol. 87, 183-189.
-
(1992)
Clin. Exp. Immunol.
, vol.87
, pp. 183-189
-
-
Wood, N.C.1
Symons, J.A.2
Dickens, E.3
Duff, G.W.4
-
4
-
-
0031042456
-
Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis
-
McInnes IB, Leung BP, Sturrock RD, Field M, Liew FY. (1997) Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis. Nat. Med. 3, 189-195.
-
(1997)
Nat. Med.
, vol.3
, pp. 189-195
-
-
McInnes, I.B.1
Leung, B.P.2
Sturrock, R.D.3
Field, M.4
Liew, F.Y.5
-
5
-
-
37549063078
-
Cytokines and anti-cytokines as therapeutics-an update
-
Tayal V, Kalra BS. (2008) Cytokines and anti-cytokines as therapeutics-an update. Eur. J. Pharmacol. 579, 1-12.
-
(2008)
Eur. J. Pharmacol.
, vol.579
, pp. 1-12
-
-
Tayal, V.1
Kalra, B.S.2
-
6
-
-
1942453342
-
Historical review: cytokines as therapeutics and targets of therapeutics
-
Vilcek J, Feldmann M. (2004) Historical review: cytokines as therapeutics and targets of therapeutics. Trends Pharmacol. Sci. 25, 201-209.
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, pp. 201-209
-
-
Vilcek, J.1
Feldmann, M.2
-
7
-
-
0242353920
-
Targeting cytokines to inflammation sites
-
Adams G, Vessillier S, Dreja H, Chernajovsky Y. (2003) Targeting cytokines to inflammation sites. Nat. Biotechnol. 21, 1314-1320.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1314-1320
-
-
Adams, G.1
Vessillier, S.2
Dreja, H.3
Chernajovsky, Y.4
-
8
-
-
2642570856
-
Methods for targeting biologicals to specific disease sites
-
Nissim A, Gofur Y, Vessillier S, Adams G, Chernajovsky Y. (2004) Methods for targeting biologicals to specific disease sites. Trends Mol. Med. 10, 269-274.
-
(2004)
Trends Mol. Med.
, vol.10
, pp. 269-274
-
-
Nissim, A.1
Gofur, Y.2
Vessillier, S.3
Adams, G.4
Chernajovsky, Y.5
-
9
-
-
0036516460
-
Matrix metalloproteinases: a tail of a frog that became a prince
-
Brinckerhoff CE, Matrisian LM. (2002) Matrix metalloproteinases: a tail of a frog that became a prince. Nat. Rev. Mol. Cell Biol. 3, 207-214.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 207-214
-
-
Brinckerhoff, C.E.1
Matrisian, L.M.2
-
10
-
-
33847183465
-
Molecular targets in osteoarthritis: metalloproteinases and their inhibitors
-
Burrage PS, Brinckerhoff CE. (2007) Molecular targets in osteoarthritis: metalloproteinases and their inhibitors. Curr. Drug Targets 8, 293-303.
-
(2007)
Curr. Drug Targets
, vol.8
, pp. 293-303
-
-
Burrage, P.S.1
Brinckerhoff, C.E.2
-
12
-
-
0037693895
-
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry
-
Visse R, Nagase H. (2003) Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ. Res. 92, 827-839.
-
(2003)
Circ. Res.
, vol.92
, pp. 827-839
-
-
Visse, R.1
Nagase, H.2
-
13
-
-
31344458952
-
Structure and function of matrix metalloproteinases and TIMPs
-
Nagase H, Visse R, Murphy G. (2006) Structure and function of matrix metalloproteinases and TIMPs. Cardiovasc. Res. 69, 562-573.
-
(2006)
Cardiovasc. Res.
, vol.69
, pp. 562-573
-
-
Nagase, H.1
Visse, R.2
Murphy, G.3
-
15
-
-
0141839771
-
Clinical implications of matrix metalloproteinases
-
Mandal M, Mandal A, Das S, Chakraborti T, Sajal C. (2003) Clinical implications of matrix metalloproteinases. Mol. Cell Biochem. 252, 305-329.
-
(2003)
Mol. Cell Biochem.
, vol.252
, pp. 305-329
-
-
Mandal, M.1
Mandal, A.2
Das, S.3
Chakraborti, T.4
Sajal, C.5
-
17
-
-
0028825270
-
Matrix metalloproteinases in brain injury
-
Rosenberg GA. (1995) Matrix metalloproteinases in brain injury. J. Neurotrauma 12, 833-842.
-
(1995)
J. Neurotrauma
, vol.12
, pp. 833-842
-
-
Rosenberg, G.A.1
-
18
-
-
0036737795
-
Matrix metalloproteinases in neuroinflammation
-
Rosenberg GA. (2002) Matrix metalloproteinases in neuroinflammation. Glia 39, 279-291.
-
(2002)
Glia
, vol.39
, pp. 279-291
-
-
Rosenberg, G.A.1
-
19
-
-
0029084524
-
Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques
-
Shah PK, Falk E, Badimon JJ, Fernandez-Ortiz A, Mailhac A, Villareal-Levy G, et al. (1995) Human monocyte-derived macrophages induce collagen breakdown in fibrous caps of atherosclerotic plaques. Potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation 92, 1565-1569.
-
(1995)
Potential role of matrix-degrading metalloproteinases and implications for plaque rupture. Circulation
, vol.92
, pp. 1565-1569
-
-
Shah, P.K.1
Falk, E.2
Badimon, J.J.3
Fernandez-Ortiz, A.4
Mailhac, A.5
Villareal-Levy, G.6
-
20
-
-
0037155057
-
Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly
-
Galis ZS, Khatri JJ. (2002) Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ. Res. 90, 251-262.
-
(2002)
Circ. Res.
, vol.90
, pp. 251-262
-
-
Galis, Z.S.1
Khatri, J.J.2
-
21
-
-
0032922277
-
Amelioration of collagen-induced arthritis and suppression of interferon-gamma, interleukin-12, and tumor necrosis factor alpha production by interferon-beta gene therapy
-
Triantaphyllopoulos KA, Williams RO, Tailor H, Chernajovsky Y. (1999) Amelioration of collagen-induced arthritis and suppression of interferon-gamma, interleukin-12, and tumor necrosis factor alpha production by interferon-beta gene therapy. Arthritis Rheum. 42, 90-99.
-
(1999)
Arthritis Rheum.
, vol.42
, pp. 90-99
-
-
Triantaphyllopoulos, K.A.1
Williams, R.O.2
Tailor, H.3
Chernajovsky, Y.4
-
22
-
-
0035020761
-
Improved pharmacokinetic properties of a polyethylene glycol-modified form of interferonbeta-1a with preserved in vitro bioactivity
-
Pepinsky RB, LePage DJ, Gill A, Chakraborty A, Vaidyanathan S, Green M, et al. (2001) Improved pharmacokinetic properties of a polyethylene glycol-modified form of interferonbeta-1a with preserved in vitro bioactivity. J. Pharmacol. Exp. Ther. 297, 1059-1066.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.297
, pp. 1059-1066
-
-
Pepinsky, R.B.1
LePage, D.J.2
Gill, A.3
Chakraborty, A.4
Vaidyanathan, S.5
Green, M.6
-
23
-
-
2442593631
-
Inhibition of established collagen-induced arthritis with a tumour necrosis factor-alpha inhibitor expressed from a self-contained doxycycline regulated plasmid
-
Gould DJ, Bright C, Chernajovsky Y. (2004) Inhibition of established collagen-induced arthritis with a tumour necrosis factor-alpha inhibitor expressed from a self-contained doxycycline regulated plasmid. Arthritis Res. Ther. 6, R103-113.
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
Gould, D.J.1
Bright, C.2
Chernajovsky, Y.3
-
24
-
-
84871404122
-
Role of a latent soluble TNF receptor type I (hsTNFRI) fusion protein in targeted treatment of endometriosis
-
Xiong ZF, Hu S, Wang ZH. (2010) Role of a latent soluble TNF receptor type I (hsTNFRI) fusion protein in targeted treatment of endometriosis. Zhonghua Yi Xue Za Zhi 90, 768-771.
-
(2010)
Zhonghua Yi Xue Za Zhi
, vol.90
, pp. 768-771
-
-
Xiong, Z.F.1
Hu, S.2
Wang, Z.H.3
-
25
-
-
0026453554
-
Early endometriosis invades the extracellular matrix
-
Spuijbroek MD, Dunselman GA, Menheere PP, Evers JL. (1992) Early endometriosis invades the extracellular matrix. Fertil. Steril. 58, 929-933.
-
(1992)
Fertil. Steril.
, vol.58
, pp. 929-933
-
-
Spuijbroek, M.D.1
Dunselman, G.A.2
Menheere, P.P.3
Evers, J.L.4
-
26
-
-
0035066014
-
Regulation of matrix metalloproteinases and their inhibitors in uterine endometrial cells of patients with and without endometriosis
-
Sillem M, Prifti S, Koch A, Neher M, Jauckus J, Runnebaum B. (2001) Regulation of matrix metalloproteinases and their inhibitors in uterine endometrial cells of patients with and without endometriosis. Eur. J. Obstet. Gynecol. Reprod. Biol. 95, 167-174.
-
(2001)
Eur. J. Obstet. Gynecol. Reprod. Biol.
, vol.95
, pp. 167-174
-
-
Sillem, M.1
Prifti, S.2
Koch, A.3
Neher, M.4
Jauckus, J.5
Runnebaum, B.6
-
27
-
-
0029974766
-
Expression of an efficient small molecular weight tumour necrosis factor/lymphotoxin antagonist
-
Neve R, Kissonerghis M, Clark J, Feldmann M, Chernajovsky Y. (1996) Expression of an efficient small molecular weight tumour necrosis factor/lymphotoxin antagonist. Cytokine 8, 365-370.
-
(1996)
Cytokine
, vol.8
, pp. 365-370
-
-
Neve, R.1
Kissonerghis, M.2
Clark, J.3
Feldmann, M.4
Chernajovsky, Y.5
-
28
-
-
0028582165
-
Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein
-
Moren A, Olofsson A, Stenman G, Sahlin P, Kanzaki T, Claesson-Welsh L, et al. (1994) Identification and characterization of LTBP-2, a novel latent transforming growth factor-beta-binding protein. J. Biol. Chem. 269, 32469-32478.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 32469-32478
-
-
Moren, A.1
Olofsson, A.2
Stenman, G.3
Sahlin, P.4
Kanzaki, T.5
Claesson-Welsh, L.6
-
29
-
-
0029565595
-
Efficient association of an amino-terminally extended form of human latent transforming growth factor-beta binding protein with the extracellular matrix
-
Olofsson A, Ichijo H, Moren A, ten Dijke P, Miyazono K, Heldin CH. (1995) Efficient association of an amino-terminally extended form of human latent transforming growth factor-beta binding protein with the extracellular matrix. J. Biol. Chem. 270, 31294-31297.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 31294-31297
-
-
Olofsson, A.1
Ichijo, H.2
Moren, A.3
Ten Dijke, P.4
Miyazono, K.5
Heldin, C.H.6
-
30
-
-
0033840527
-
Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta
-
Saharinen J, Keski-Oja J. (2000) Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta. Mol. Biol. Cell 11, 2691-2704.
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 2691-2704
-
-
Saharinen, J.1
Keski-Oja, J.2
-
31
-
-
0024372267
-
Recombinant TGF-beta 1 is synthesized as a two-component latent complex that shares some structural features with the native platelet latent TGF-beta 1 complex
-
Wakefield LM, Smith DM, Broz S, Jackson M, Levinson AD, Sporn MB. (1989) Recombinant TGF-beta 1 is synthesized as a two-component latent complex that shares some structural features with the native platelet latent TGF-beta 1 complex. Growth Factors 1, 203-218.
-
(1989)
Growth Factors
, vol.1
, pp. 203-218
-
-
Wakefield, L.M.1
Smith, D.M.2
Broz, S.3
Jackson, M.4
Levinson, A.D.5
Sporn, M.B.6
-
32
-
-
0024312217
-
Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins
-
Brunner AM, Marquardt H, Malacko AR, Lioubin MN, Purchio AF. (1989) Site-directed mutagenesis of cysteine residues in the pro region of the transforming growth factor beta 1 precursor. Expression and characterization of mutant proteins. J. Biol. Chem. 264, 13660-13664.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13660-13664
-
-
Brunner, A.M.1
Marquardt, H.2
Malacko, A.R.3
Lioubin, M.N.4
Purchio, A.F.5
-
33
-
-
0017566429
-
Impaired intracellular migration and altered solubility of nonglycosylated glycoproteins of vesicular stomatitis virus and Sindbis virus
-
Leavitt R, Schlesinger S, Kornfeld S. (1977) Impaired intracellular migration and altered solubility of nonglycosylated glycoproteins of vesicular stomatitis virus and Sindbis virus. J. Biol. Chem. 252, 9018-9023.
-
(1977)
J. Biol. Chem.
, vol.252
, pp. 9018-9023
-
-
Leavitt, R.1
Schlesinger, S.2
Kornfeld, S.3
-
34
-
-
0023906050
-
Influence of new glycosylation sites on expression of the vesicular stomatitis virus G protein at the plasma membrane
-
Machamer CE, Rose JK. (1988) Influence of new glycosylation sites on expression of the vesicular stomatitis virus G protein at the plasma membrane. J. Biol. Chem. 263, 5948-5954.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 5948-5954
-
-
Machamer, C.E.1
Rose, J.K.2
-
35
-
-
0023597393
-
The relationship of N-linked glycosylation and heavy chain-binding protein association with the secretion of glycoproteins
-
Dorner AJ, Bole DG, Kaufman RJ. (1987) The relationship of N-linked glycosylation and heavy chain-binding protein association with the secretion of glycoproteins. J. Cell Biol. 105, 2665-2674.
-
(1987)
J. Cell Biol.
, vol.105
, pp. 2665-2674
-
-
Dorner, A.J.1
Bole, D.G.2
Kaufman, R.J.3
-
36
-
-
0024364117
-
Transforming growth factor beta 1: importance of glycosylation and acidic proteases for processing and secretion
-
Sha X, Brunner AM, Purchio AF, Gentry LE. (1989) Transforming growth factor beta 1: importance of glycosylation and acidic proteases for processing and secretion. Mol. Endocrinol. 3, 1090-1098.
-
(1989)
Mol. Endocrinol.
, vol.3
, pp. 1090-1098
-
-
Sha, X.1
Brunner, A.M.2
Purchio, A.F.3
Gentry, L.E.4
-
37
-
-
0026548073
-
Dominant negative mutants of transforming growth factor-beta 1 inhibit the secretion of different transforming growth factorbeta isoforms
-
Lopez AR, Cook J, Deininger PL, Derynck R. (1992) Dominant negative mutants of transforming growth factor-beta 1 inhibit the secretion of different transforming growth factorbeta isoforms. Mol. Cell Biol. 12, 1674-1679.
-
(1992)
Mol. Cell Biol.
, vol.12
, pp. 1674-1679
-
-
Lopez, A.R.1
Cook, J.2
Deininger, P.L.3
Derynck, R.4
-
38
-
-
0026793735
-
Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 (414) precursors and of cysteine residues within mature TGF beta 1: effects on secretion and bioactivity
-
Brunner AM, Lioubin MN, Marquardt H, Malacko AR, Wang WC, Shapiro RA, et al. (1992) Site-directed mutagenesis of glycosylation sites in the transforming growth factor-beta 1 (TGF beta 1) and TGF beta 2 (414) precursors and of cysteine residues within mature TGF beta 1: effects on secretion and bioactivity. Mol. Endocrinol. 6, 1691-1700.
-
(1992)
Mol. Endocrinol.
, vol.6
, pp. 1691-1700
-
-
Brunner, A.M.1
Lioubin, M.N.2
Marquardt, H.3
Malacko, A.R.4
Wang, W.C.5
Shapiro, R.A.6
-
39
-
-
25444435396
-
Glycoengineering: the effect of glycosylation on the properties of therapeutic proteins
-
Sinclair AM, Elliott S. (2005) Glycoengineering: the effect of glycosylation on the properties of therapeutic proteins. J. Pharm. Sci. 94, 1626-1635.
-
(2005)
J. Pharm. Sci.
, vol.94
, pp. 1626-1635
-
-
Sinclair, A.M.1
Elliott, S.2
-
40
-
-
33947611087
-
Glycosylation of therapeutic proteins in different production systems
-
Werner RG, Kopp K, Schlueter M. (2007) Glycosylation of therapeutic proteins in different production systems. Acta Paediatr. Suppl. 96, 17-22.
-
(2007)
Acta Paediatr. Suppl.
, vol.96
, pp. 17-22
-
-
Werner, R.G.1
Kopp, K.2
Schlueter, M.3
-
41
-
-
0023879547
-
Recombinant type 1 transforming growth factor beta precursor produced in Chinese hamster ovary cells is glycosylated and phosphorylated
-
Brunner AM, Gentry LE, Cooper JA, Purchio AF. (1988) Recombinant type 1 transforming growth factor beta precursor produced in Chinese hamster ovary cells is glycosylated and phosphorylated. Mol. Cell Biol. 8, 2229-2232.
-
(1988)
Mol. Cell Biol.
, vol.8
, pp. 2229-2232
-
-
Brunner, A.M.1
Gentry, L.E.2
Cooper, J.A.3
Purchio, A.F.4
-
42
-
-
0023710423
-
Identification of mannose 6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor-beta 1 precursor
-
Purchio AF, Cooper JA, Brunner AM, Lioubin MN, Gentry LE, Kovacina KS. (1988) Identification of mannose 6-phosphate in two asparagine-linked sugar chains of recombinant transforming growth factor-beta 1 precursor. J. Biol. Chem. 263, 14211-14215.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 14211-14215
-
-
Purchio, A.F.1
Cooper, J.A.2
Brunner, A.M.3
Lioubin, M.N.4
Gentry, L.E.5
Kovacina, K.S.6
-
43
-
-
0025632985
-
Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution
-
Wakefield LM, Winokur TS, Hollands RS, Christopherson K, Levinson AD, Sporn MB. (1990) Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution. J. Clin. Invest. 86, 1976-1984.
-
(1990)
J. Clin. Invest.
, vol.86
, pp. 1976-1984
-
-
Wakefield, L.M.1
Winokur, T.S.2
Hollands, R.S.3
Christopherson, K.4
Levinson, A.D.5
Sporn, M.B.6
-
44
-
-
0024539847
-
Role for carbohydrate structures in TGF-beta 1 latency
-
Miyazono K, Heldin CH. (1989) Role for carbohydrate structures in TGF-beta 1 latency. Nature 338, 158-160.
-
(1989)
Nature
, vol.338
, pp. 158-160
-
-
Miyazono, K.1
Heldin, C.H.2
-
45
-
-
0030820363
-
Role of carbohydrate structures in the binding of beta1-latency-associated peptide to ligands
-
Yang Y, Dignam JD, Gentry LE. (1997) Role of carbohydrate structures in the binding of beta1-latency-associated peptide to ligands. Biochemistry 36, 11923-11932.
-
(1997)
Biochemistry
, vol.36
, pp. 11923-11932
-
-
Yang, Y.1
Dignam, J.D.2
Gentry, L.E.3
-
46
-
-
0032534987
-
Modulation of circulatory residence of recombinant acetylcholinesterase through biochemical or genetic manipulation of sialylation levels
-
Chitlaru T, Kronman C, Zeevi M, Kam M, Harel A, Ordentlich A, et al. (1998) Modulation of circulatory residence of recombinant acetylcholinesterase through biochemical or genetic manipulation of sialylation levels. Biochem. J. 336, 647-658.
-
(1998)
Biochem. J.
, vol.336
, pp. 647-658
-
-
Chitlaru, T.1
Kronman, C.2
Zeevi, M.3
Kam, M.4
Harel, A.5
Ordentlich, A.6
-
48
-
-
0033017354
-
Immunologic therapy of multiple sclerosis
-
Arnason BG. (1999) Immunologic therapy of multiple sclerosis. Annu. Rev. Med. 50, 291-302.
-
(1999)
Annu. Rev. Med.
, vol.50
, pp. 291-302
-
-
Arnason, B.G.1
-
49
-
-
0034982596
-
Immunological update on multiple sclerosis
-
Hohlfeld R, Wekerle H. (2001) Immunological update on multiple sclerosis. Curr. Opin. Neurol. 14, 299-304.
-
(2001)
Curr. Opin. Neurol.
, vol.14
, pp. 299-304
-
-
Hohlfeld, R.1
Wekerle, H.2
-
50
-
-
0028245010
-
Interleukin-10 prevents experimental allergic encephalomyelitis in rats
-
Rott O, Fleischer B, Cash E. (1994) Interleukin-10 prevents experimental allergic encephalomyelitis in rats. Eur. J. Immunol. 24, 1434-1440.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 1434-1440
-
-
Rott, O.1
Fleischer, B.2
Cash, E.3
-
51
-
-
0032193696
-
IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10-and IL-4-deficient and transgenic mice
-
Bettelli E, Das MP, Howard ED, Weiner HL, Sobel RA, Kuchroo VK. (1998) IL-10 is critical in the regulation of autoimmune encephalomyelitis as demonstrated by studies of IL-10-and IL-4-deficient and transgenic mice. J. Immunol. 161, 3299-3306.
-
(1998)
J. Immunol.
, vol.161
, pp. 3299-3306
-
-
Bettelli, E.1
Das, M.P.2
Howard, E.D.3
Weiner, H.L.4
Sobel, R.A.5
Kuchroo, V.K.6
-
52
-
-
0032584685
-
IL-10 reduces rat brain injury following focal stroke
-
Spera PA, Ellison JA, Feuerstein GZ, Barone FC. (1998) IL-10 reduces rat brain injury following focal stroke. Neurosci. Lett. 251, 189-192.
-
(1998)
Neurosci. Lett.
, vol.251
, pp. 189-192
-
-
Spera, P.A.1
Ellison, J.A.2
Feuerstein, G.Z.3
Barone, F.C.4
-
53
-
-
0035126792
-
Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat
-
Plunkett JA, Yu CG, Easton JM, Bethea JR, Yezierski RP. (2001) Effects of interleukin-10 (IL-10) on pain behavior and gene expression following excitotoxic spinal cord injury in the rat. Exp. Neurol. 168, 144-154.
-
(2001)
Exp. Neurol.
, vol.168
, pp. 144-154
-
-
Plunkett, J.A.1
Yu, C.G.2
Easton, J.M.3
Bethea, J.R.4
Yezierski, R.P.5
-
54
-
-
5444234867
-
Erythropoietin: novel approaches to neuroprotection in human brain disease
-
Ehrenreich H, Aust C, Krampe H, Jahn H, Jacob S, Herrmann M. (2004) Erythropoietin: novel approaches to neuroprotection in human brain disease. Metab. Brain Dis. 19, 195-206.
-
(2004)
Metab. Brain Dis.
, vol.19
, pp. 195-206
-
-
Ehrenreich, H.1
Aust, C.2
Krampe, H.3
Jahn, H.4
Jacob, S.5
Herrmann, M.6
-
55
-
-
2942562430
-
Recombinant erythropoietin as a neuroprotective treatment: in vitro and in vivo models
-
Juul S. (2004) Recombinant erythropoietin as a neuroprotective treatment: in vitro and in vivo models. Clin. Perinatol. 31, 129-142.
-
(2004)
Clin. Perinatol.
, vol.31
, pp. 129-142
-
-
Juul, S.1
-
56
-
-
20044373442
-
Emerging biological roles for erythropoietin in the nervous system
-
Brines M, Cerami A. (2005) Emerging biological roles for erythropoietin in the nervous system. Nat. Rev. Neurosci. 6, 484-494.
-
(2005)
Nat. Rev. Neurosci.
, vol.6
, pp. 484-494
-
-
Brines, M.1
Cerami, A.2
-
57
-
-
0037064261
-
Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis
-
Agnello D, Bigini P, Villa P, Mennini T, Cerami A, Brines ML, et al. (2002) Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Res. 952, 128-134.
-
(2002)
Brain Res.
, vol.952
, pp. 128-134
-
-
Agnello, D.1
Bigini, P.2
Villa, P.3
Mennini, T.4
Cerami, A.5
Brines, M.L.6
-
58
-
-
9644278256
-
Beneficial effect of erythropoietin on experimental allergic encephalomyelitis
-
Li W, Maeda Y, Yuan RR, Elkabes S, Cook S, Dowling P. (2004) Beneficial effect of erythropoietin on experimental allergic encephalomyelitis. Ann. Neurol. 56, 767-777.
-
(2004)
Ann. Neurol.
, vol.56
, pp. 767-777
-
-
Li, W.1
Maeda, Y.2
Yuan, R.R.3
Elkabes, S.4
Cook, S.5
Dowling, P.6
-
59
-
-
13844251822
-
Erythropoietin treatment improves neurological functional recovery in EAE mice
-
Zhang J, Li Y, Cui Y, Chen J, Lu M, Elias SB, et al. (2005) Erythropoietin treatment improves neurological functional recovery in EAE mice. Brain Res. 1034, 34-39.
-
(2005)
Brain Res.
, vol.1034
, pp. 34-39
-
-
Zhang, J.1
Li, Y.2
Cui, Y.3
Chen, J.4
Lu, M.5
Elias, S.B.6
-
60
-
-
0036892580
-
Matrix metalloproteinases and neuroinflammation in multiple sclerosis
-
Rosenberg GA. (2002) Matrix metalloproteinases and neuroinflammation in multiple sclerosis. Neuroscientist 8, 586-595.
-
(2002)
Neuroscientist
, vol.8
, pp. 586-595
-
-
Rosenberg, G.A.1
-
61
-
-
30444450277
-
Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with relapsing-remitting multiple sclerosis treated with interferon beta
-
Boz C, Ozmenoglu M, Velioglu S, Kilinc K, Orem A, Alioglu Z, et al. (2006) Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with relapsing-remitting multiple sclerosis treated with interferon beta. Clin. Neurol. Neurosurg. 108, 124-128.
-
(2006)
Clin. Neurol. Neurosurg.
, vol.108
, pp. 124-128
-
-
Boz, C.1
Ozmenoglu, M.2
Velioglu, S.3
Kilinc, K.4
Orem, A.5
Alioglu, Z.6
-
62
-
-
34447104602
-
Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators
-
YongVW, Zabad RK, Agrawal S, Goncalves Dasilva A, Metz LM. (2007) Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators. J. Neurol. Sci. 259, 79-84.
-
(2007)
J. Neurol. Sci.
, vol.259
, pp. 79-84
-
-
Yong, V.W.1
Zabad, R.K.2
Agrawal, S.3
Goncalves Dasilva, A.4
Metz, L.M.5
-
63
-
-
34848841517
-
Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis
-
Ehrenreich H, Fischer B, Norra C, Schellenberger F, Stender N, Stiefel M, et al. (2007) Exploring recombinant human erythropoietin in chronic progressive multiple sclerosis. Brain 130, 2577-2588.
-
(2007)
Brain
, vol.130
, pp. 2577-2588
-
-
Ehrenreich, H.1
Fischer, B.2
Norra, C.3
Schellenberger, F.4
Stender, N.5
Stiefel, M.6
-
64
-
-
0024436509
-
Transforming growth factors beta 1 and beta 2: cytokines with identical immunosuppressive effects and a potential role in the regulation of autoimmune T cell function
-
Schluesener HJ, Lider O. (1989) Transforming growth factors beta 1 and beta 2: cytokines with identical immunosuppressive effects and a potential role in the regulation of autoimmune T cell function. J. Neuroimmunol. 24, 249-258.
-
(1989)
J. Neuroimmunol.
, vol.24
, pp. 249-258
-
-
Schluesener, H.J.1
Lider, O.2
-
65
-
-
0026006736
-
Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1
-
Johns LD, Flanders KC, Ranges GE, Sriram S. (1991) Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1. J. Immunol. 147, 1792-1796.
-
(1991)
J. Immunol.
, vol.147
, pp. 1792-1796
-
-
Johns, L.D.1
Flanders, K.C.2
Ranges, G.E.3
Sriram, S.4
-
67
-
-
17644372231
-
Treatment with recombinant interferon-beta reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis
-
van Holten J, Reedquist K, Sattonet-Roche P, Smeets TJ, Plater-Zyberk C, Vervoordeldonk MJ. (2004) Treatment with recombinant interferon-beta reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis. Arthritis Res. Ther. 6, R239-249.
-
(2004)
Arthritis Res. Ther.
, vol.6
-
-
van Holten, J.1
Reedquist, K.2
Sattonet-Roche, P.3
Smeets, T.J.4
Plater-Zyberk, C.5
Vervoordeldonk, M.J.6
-
68
-
-
2342433268
-
Fistulising Crohn's disease: MMPs gone awry
-
Schuppan D, Freitag T. (2004) Fistulising Crohn's disease: MMPs gone awry. Gut 53, 622-624.
-
(2004)
Gut
, vol.53
, pp. 622-624
-
-
Schuppan, D.1
Freitag, T.2
-
69
-
-
0033933804
-
Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease
-
von Lampe B, Barthel B, Coupland SE, Riecken EO, Rosewicz S. (2000) Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease. Gut 47, 63-73.
-
(2000)
Gut
, vol.47
, pp. 63-73
-
-
von Lampe, B.1
Barthel, B.2
Coupland, S.E.3
Riecken, E.O.4
Rosewicz, S.5
-
70
-
-
0035899894
-
Matrix metalloproteinase hypothesis of plaque rupture: players keep piling up but questions remain
-
Shah PK, Galis ZS. (2001) Matrix metalloproteinase hypothesis of plaque rupture: players keep piling up but questions remain. Circulation 104, 1878-1880.
-
(2001)
Circulation
, vol.104
, pp. 1878-1880
-
-
Shah, P.K.1
Galis, Z.S.2
-
71
-
-
0000614773
-
Interleukin-10 blocks atherosclerotic events in vitro and in vivo
-
Pinderski Oslund LJ, Hedrick CC, Olvera T, Hagenbaugh A, Territo M, Berliner JA, et al. (1999) Interleukin-10 blocks atherosclerotic events in vitro and in vivo. Arterioscler. Thromb. Vasc. Biol. 19, 2847-2853.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 2847-2853
-
-
Pinderski Oslund, L.J.1
Hedrick, C.C.2
Olvera, T.3
Hagenbaugh, A.4
Territo, M.5
Berliner, J.A.6
-
72
-
-
0035859839
-
Serum levels of the antiinflammatory cytokine interleukin-10 are decreased in patients with unstable angina
-
Smith DA, Irving SD, Sheldon J, Cole D, Kaski JC. (2001) Serum levels of the antiinflammatory cytokine interleukin-10 are decreased in patients with unstable angina. Circulation 104, 746-749.
-
(2001)
Circulation
, vol.104
, pp. 746-749
-
-
Smith, D.A.1
Irving, S.D.2
Sheldon, J.3
Cole, D.4
Kaski, J.C.5
-
73
-
-
0033948508
-
Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10(-/-) mice and intestinal inflammation
-
Rennick DM, Fort MM. (2000) Lessons from genetically engineered animal models. XII. IL-10-deficient (IL-10(-/-) mice and intestinal inflammation. Am. J. Physiol. Gastrointest. Liver Physiol. 278, G829-833.
-
(2000)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.278
-
-
Rennick, D.M.1
Fort, M.M.2
-
74
-
-
1542580481
-
IL-10 and its related cytokines for treatment of inflammatory bowel disease
-
Li MC, He SH. (2004) IL-10 and its related cytokines for treatment of inflammatory bowel disease. World J. Gastroenterol. 10, 620-625.
-
(2004)
World J. Gastroenterol.
, vol.10
, pp. 620-625
-
-
Li, M.C.1
He, S.H.2
-
75
-
-
0037103231
-
Role of IL-10 for induction of anemia during inflammation
-
Tilg H, Ulmer H, Kaser A, Weiss G. (2002) Role of IL-10 for induction of anemia during inflammation. J. Immunol. 169, 2204-2209.
-
(2002)
J. Immunol.
, vol.169
, pp. 2204-2209
-
-
Tilg, H.1
Ulmer, H.2
Kaser, A.3
Weiss, G.4
-
76
-
-
0036153395
-
Treatment of Crohns disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma
-
Tilg H, van Montfrans C, van den Ende A, Kaser A, van Deventer SJ, Schreiber S, et al. (2002) Treatment of Crohns disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon gamma. Gut 50, 191-195.
-
(2002)
Gut
, vol.50
, pp. 191-195
-
-
Tilg, H.1
van Montfrans, C.2
van den Ende, A.3
Kaser, A.4
van Deventer, S.J.5
Schreiber, S.6
-
77
-
-
0025764757
-
Interleukin-4: a prototypic immunoregulatory lymphokine
-
Paul WE. (1991) Interleukin-4: a prototypic immunoregulatory lymphokine. Blood 77, 1859-1870.
-
(1991)
Blood
, vol.77
, pp. 1859-1870
-
-
Paul, W.E.1
-
78
-
-
0034512009
-
Interleukin (IL)-4 deficiency does not influence fatty streak formation in C57BL/6 mice
-
George J, Mulkins M, Shaish A, Casey S, Schatzman R, Sigal E, et al. (2000) Interleukin (IL)-4 deficiency does not influence fatty streak formation in C57BL/6 mice. Atherosclerosis 153, 403-411.
-
(2000)
Atherosclerosis
, vol.153
, pp. 403-411
-
-
George, J.1
Mulkins, M.2
Shaish, A.3
Casey, S.4
Schatzman, R.5
Sigal, E.6
-
79
-
-
0035967480
-
T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemia
-
Huber SA, Sakkinen P, David C, Newell MK, Tracy RP. (2001) T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemia. Circulation 103, 2610-2616.
-
(2001)
Circulation
, vol.103
, pp. 2610-2616
-
-
Huber, S.A.1
Sakkinen, P.2
David, C.3
Newell, M.K.4
Tracy, R.P.5
-
80
-
-
0032983215
-
Stat6 activation is essential for interleukin-4 induction of P-selectin transcription in human umbilical vein endothelial cells
-
Khew-Goodall Y, Wadham C, Stein BN, Gamble JR, Vadas MA. (1999) Stat6 activation is essential for interleukin-4 induction of P-selectin transcription in human umbilical vein endothelial cells. Arterioscler. Thromb. Vasc. Biol. 19, 1421-1429.
-
(1999)
Arterioscler. Thromb. Vasc. Biol.
, vol.19
, pp. 1421-1429
-
-
Khew-Goodall, Y.1
Wadham, C.2
Stein, B.N.3
Gamble, J.R.4
Vadas, M.A.5
-
81
-
-
0034033875
-
Interleukin-4 augments acetylated LDL-induced cholesterol esterification in macrophages
-
Cornicelli JA, Butteiger D, Rateri DL, Welch K, Daugherty A. (2000) Interleukin-4 augments acetylated LDL-induced cholesterol esterification in macrophages. J. Lipid Res. 41, 376-383.
-
(2000)
J. Lipid Res.
, vol.41
, pp. 376-383
-
-
Cornicelli, J.A.1
Butteiger, D.2
Rateri, D.L.3
Welch, K.4
Daugherty, A.5
-
82
-
-
82955163194
-
Molecular engineering of short half-life small peptides (VIP, alpha-MSH and gamma3-MSH) fused to latency-associated peptides results in improved anti-inflammatory therapeutics
-
Vessillier S, Adams G, Montero-Melendez T, Jones R, Seed M, Perretti M, Chernajovsky Y. (2012) Molecular engineering of short half-life small peptides (VIP, alpha-MSH and gamma3-MSH) fused to latency-associated peptides results in improved anti-inflammatory therapeutics. Ann Rheum Dis 17, 143-149.
-
(2012)
Ann Rheum Dis
, vol.17
, pp. 143-149
-
-
Vessillier, S.1
Adams, G.2
Montero-Melendez, T.3
Jones, R.4
Seed, M.5
Perretti, M.6
Chernajovsky, Y.7
-
83
-
-
32944459251
-
Matrix metalloproteinases: roles in cancer and metastasis
-
Fingleton B. (2006) Matrix metalloproteinases: roles in cancer and metastasis. Front Biosci. 11, 479-491.
-
(2006)
Front Biosci.
, vol.11
, pp. 479-491
-
-
Fingleton, B.1
-
84
-
-
30344480772
-
Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis
-
Ii M, Yamamoto H, Adachi Y, Maruyama Y, Shinomura Y. (2006) Role of matrix metalloproteinase-7 (matrilysin) in human cancer invasion, apoptosis, growth, and angiogenesis. Exp. Biol. Med. (Maywood) 231, 20-27.
-
(2006)
Exp. Biol. Med. (Maywood)
, vol.231
, pp. 20-27
-
-
Ii, M.1
Yamamoto, H.2
Adachi, Y.3
Maruyama, Y.4
Shinomura, Y.5
-
85
-
-
77953032463
-
Matrix metalloproteinases involvement in pathologic conditions
-
Amalinei C, Caruntu ID, Giusca SE, Balan RA. (2010) Matrix metalloproteinases involvement in pathologic conditions. Rom. J. Morphol. Embryol. 51, 215-228.
-
(2010)
Rom. J. Morphol. Embryol.
, vol.51
, pp. 215-228
-
-
Amalinei, C.1
Caruntu, I.D.2
Giusca, S.E.3
Balan, R.A.4
-
86
-
-
0014957380
-
Effects on smooth muscle preparations of unidentified vasoactive peptides from intestine and lung
-
Piper PJ, Said SI, Vane JR. (1970) Effects on smooth muscle preparations of unidentified vasoactive peptides from intestine and lung. Nature 225, 1144-1146.
-
(1970)
Nature
, vol.225
, pp. 1144-1146
-
-
Piper, P.J.1
Said, S.I.2
Vane, J.R.3
-
87
-
-
0014954352
-
Polypeptide with broad biological activity: isolation from small intestine
-
Said SI, Mutt V. (1970) Polypeptide with broad biological activity: isolation from small intestine. Science 169, 1217-1218.
-
(1970)
Science
, vol.169
, pp. 1217-1218
-
-
Said, S.I.1
Mutt, V.2
-
88
-
-
0036079049
-
Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) as modulators of both innate and adaptive immunity
-
Ganea D, Delgado M. (2002) Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (PACAP) as modulators of both innate and adaptive immunity. Crit. Rev. Oral Biol. Med. 13, 229-237.
-
(2002)
Crit. Rev. Oral Biol. Med.
, vol.13
, pp. 229-237
-
-
Ganea, D.1
Delgado, M.2
-
89
-
-
0034749277
-
Vasoactive intestinal peptide: cardiovascular effects
-
Henning RJ, Sawmiller DR. (2001) Vasoactive intestinal peptide: cardiovascular effects. Cardiovasc. Res. 49, 27-37.
-
(2001)
Cardiovasc. Res.
, vol.49
, pp. 27-37
-
-
Henning, R.J.1
Sawmiller, D.R.2
-
90
-
-
0028618822
-
Antiinflammatory effects of the neuropeptide alpha-MSH in acute, chronic, and systemic inflammation
-
Lipton JM, Ceriani G, Macaluso A, McCoy D, Carnes K, Biltz J, et al. (1994) Antiinflammatory effects of the neuropeptide alpha-MSH in acute, chronic, and systemic inflammation. Ann. N. Y. Acad. Sci. 741, 137-148.
-
(1994)
Ann. N. Y. Acad. Sci.
, vol.741
, pp. 137-148
-
-
Lipton, J.M.1
Ceriani, G.2
Macaluso, A.3
McCoy, D.4
Carnes, K.5
Biltz, J.6
-
91
-
-
0024564708
-
Comparison of vertebrate collagenase and gelatinase using a new fluorogenic substrate peptide
-
Stack MS, Gray RD. (1989) Comparison of vertebrate collagenase and gelatinase using a new fluorogenic substrate peptide. J. Biol. Chem. 264, 4277-4281.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 4277-4281
-
-
Stack, M.S.1
Gray, R.D.2
-
92
-
-
0028914517
-
Reconstructed 19 kDa catalytic domain of gelatinase A is an active proteinase
-
Ye QZ, Johnson LL, Yu AE, Hupe D. (1995) Reconstructed 19 kDa catalytic domain of gelatinase A is an active proteinase. Biochemistry 34, 4702-4708.
-
(1995)
Biochemistry
, vol.34
, pp. 4702-4708
-
-
Ye, Q.Z.1
Johnson, L.L.2
Yu, A.E.3
Hupe, D.4
-
93
-
-
0030994111
-
A gene delivery system activatable by diseaseassociated matrix metalloproteinases
-
Peng KW, Morling FJ, Cosset FL, Murphy G, Russell SJ. (1997) A gene delivery system activatable by diseaseassociated matrix metalloproteinases. Hum. Gene. Ther. 8, 729-738.
-
(1997)
Hum. Gene. Ther.
, vol.8
, pp. 729-738
-
-
Peng, K.W.1
Morling, F.J.2
Cosset, F.L.3
Murphy, G.4
Russell, S.J.5
-
94
-
-
15344344686
-
Latent cytokines: development of novel cleavage sites and kinetic analysis of their differential sensitivity to MMP-1 and MMP-3
-
Vessillier S, Adams G, Chernajovsky Y. (2004) Latent cytokines: development of novel cleavage sites and kinetic analysis of their differential sensitivity to MMP-1 and MMP-3. Protein Eng. Des. Sel. 17, 829-835.
-
(2004)
Protein Eng. Des. Sel.
, vol.17
, pp. 829-835
-
-
Vessillier, S.1
Adams, G.2
Chernajovsky, Y.3
-
95
-
-
0345211445
-
Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins
-
Tortorella MD, Burn TC, Pratta MA, Abbaszade I, Hollis JM, Liu R, et al. (1999) Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins. Science 284, 1664-1666.
-
(1999)
Science
, vol.284
, pp. 1664-1666
-
-
Tortorella, M.D.1
Burn, T.C.2
Pratta, M.A.3
Abbaszade, I.4
Hollis, J.M.5
Liu, R.6
-
96
-
-
0035884605
-
Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo
-
Sandy JD, Verscharen C. (2001) Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo. Biochem. J. 358, 615-626.
-
(2001)
Biochem. J.
, vol.358
, pp. 615-626
-
-
Sandy, J.D.1
Verscharen, C.2
-
97
-
-
41949131462
-
ADAMTS-5: the story so far
-
Fosang AJ, Rogerson FM, East CJ, Stanton H. (2008) ADAMTS-5: the story so far. Eur. Cell Mater. 15, 11-26.
-
(2008)
Eur. Cell Mater.
, vol.15
, pp. 11-26
-
-
Fosang, A.J.1
Rogerson, F.M.2
East, C.J.3
Stanton, H.4
-
98
-
-
30544436016
-
A contentious issue finds some clarity: on the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis
-
Sandy JD. (2006) A contentious issue finds some clarity: on the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis. Osteoarthritis Cartilage 14, 95-100.
-
(2006)
Osteoarthritis Cartilage
, vol.14
, pp. 95-100
-
-
Sandy, J.D.1
-
99
-
-
34249681972
-
Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate
-
Hills R, Mazzarella R, Fok K, Liu M, Nemirovskiy O, Leone J, et al. (2007) Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals matrilin-3 as a novel substrate. J. Biol. Chem. 282, 11101-11109.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11101-11109
-
-
Hills, R.1
Mazzarella, R.2
Fok, K.3
Liu, M.4
Nemirovskiy, O.5
Leone, J.6
-
100
-
-
0025324976
-
The pro domain of pre-protransforming growth factor beta 1 when independently expressed is a functional binding protein for the mature growth factor
-
Gentry LE, Nash BW. (1990) The pro domain of pre-protransforming growth factor beta 1 when independently expressed is a functional binding protein for the mature growth factor. Biochemistry 29, 6851-6857.
-
(1990)
Biochemistry
, vol.29
, pp. 6851-6857
-
-
Gentry, L.E.1
Nash, B.W.2
-
101
-
-
0029897379
-
The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice
-
Bottinger EP, Factor VM, Tsang ML, Weatherbee JA, Kopp JB, Qian SW, et al. (1996) The recombinant proregion of transforming growth factor beta1 (latency-associated peptide) inhibits active transforming growth factor beta1 in transgenic mice. Proc. Natl. Acad. Sci. U S A 93, 5877-5882.
-
(1996)
Proc. Natl. Acad. Sci. U S A
, vol.93
, pp. 5877-5882
-
-
Bottinger, E.P.1
Factor, V.M.2
Tsang, M.L.3
Weatherbee, J.A.4
Kopp, J.B.5
Qian, S.W.6
-
102
-
-
0033135025
-
Regulation of transforming growth factor beta1 by nitric oxide
-
Vodovotz Y, Chesler L, Chong H, Kim SJ, Simpson JT, DeGraff W, et al. (1999) Regulation of transforming growth factor beta1 by nitric oxide. Cancer Res. 59, 2142-2149.
-
(1999)
Cancer Res.
, vol.59
, pp. 2142-2149
-
-
Vodovotz, Y.1
Chesler, L.2
Chong, H.3
Kim, S.J.4
Simpson, J.T.5
DeGraff, W.6
-
103
-
-
0030022404
-
Structural characterization of the latent complex between transforming growth factor beta 1 and beta 1-latency-associated peptide
-
McMahon GA, Dignam JD, Gentry LE. (1996) Structural characterization of the latent complex between transforming growth factor beta 1 and beta 1-latency-associated peptide. Biochem. J. 313, 343-351.
-
(1996)
Biochem. J.
, vol.313
, pp. 343-351
-
-
McMahon, G.A.1
Dignam, J.D.2
Gentry, L.E.3
-
104
-
-
44849129542
-
Latency associated peptide has in vitro and in vivo immune effects independent of TGF-beta1
-
Ali NA, Gaughan AA, Orosz CG, Baran CP, McMaken S, Wang Y, et al. (2008) Latency associated peptide has in vitro and in vivo immune effects independent of TGF-beta1. PLoS One 3, e1914.
-
(2008)
PLoS One
, vol.3
-
-
Ali, N.A.1
Gaughan, A.A.2
Orosz, C.G.3
Baran, C.P.4
McMaken, S.5
Wang, Y.6
-
105
-
-
70449393157
-
In vitro-and in vivo-targeted tumor lysis by an MMP2 cleavable melittin-LAP fusion protein
-
Holle L, Song W, Holle E, Wei Y, Li J, Wagner TE, et al. (2009) In vitro-and in vivo-targeted tumor lysis by an MMP2 cleavable melittin-LAP fusion protein. Int. J. Oncol. 35, 829-835.
-
(2009)
Int. J. Oncol.
, vol.35
, pp. 829-835
-
-
Holle, L.1
Song, W.2
Holle, E.3
Wei, Y.4
Li, J.5
Wagner, T.E.6
-
106
-
-
0347475762
-
A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo
-
Holle L, Song W, Holle E, Wei Y, Wagner T, Yu X. (2003) A matrix metalloproteinase 2 cleavable melittin/avidin conjugate specifically targets tumor cells in vitro and in vivo. Int. J. Oncol. 22, 93-98.
-
(2003)
Int. J. Oncol.
, vol.22
, pp. 93-98
-
-
Holle, L.1
Song, W.2
Holle, E.3
Wei, Y.4
Wagner, T.5
Yu, X.6
-
107
-
-
3042737827
-
Membrane disrupting lytic peptides for cancer treatments
-
Leuschner C, Hansel W. (2004) Membrane disrupting lytic peptides for cancer treatments. Curr. Pharm. Des. 10, 2299-2310.
-
(2004)
Curr. Pharm. Des.
, vol.10
, pp. 2299-2310
-
-
Leuschner, C.1
Hansel, W.2
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