메뉴 건너뛰기




Volumn 8, Issue 10, 2013, Pages

5-HTT Deficiency Affects Neuroplasticity and Increases Stress Sensitivity Resulting in Altered Spatial Learning Performance in the Morris Water Maze but Not in the Barnes Maze

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; KI 67 ANTIGEN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; NERVE PROTEIN; NEUROGENIC DIFFERENTIATION FACTOR; SEROTONIN TRANSPORTER; SLC6A4 PROTEIN, MOUSE;

EID: 84886039203     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078238     Document Type: Article
Times cited : (41)

References (143)
  • 1
    • 79952012111 scopus 로고    scopus 로고
    • Looking on the Bright Side of Serotonin Transporter Gene Variation
    • doi: 10.1016/j.biopsych.2010.09.024
    • Homberg JR, Lesch K-P, (2011) Looking on the Bright Side of Serotonin Transporter Gene Variation. Biol Psychiatry 69: 513-519. doi:10.1016/j.biopsych.2010.09.024. PubMed: 21047622.
    • (2011) Biol Psychiatry , vol.69 , pp. 513-519
    • Homberg, J.R.1    Lesch, K.-P.2
  • 2
    • 31544450567 scopus 로고    scopus 로고
    • Modulation of anxiety circuits by serotonergic systems
    • doi: 10.1080/10253890500492787
    • Lowry CA, Johnson PL, Hay-Schmidt A, Mikkelsen J, Shekhar A, (2005) Modulation of anxiety circuits by serotonergic systems. Stress 8: 233-246. doi:10.1080/10253890500492787. PubMed: 16423712.
    • (2005) Stress , vol.8 , pp. 233-246
    • Lowry, C.A.1    Johnson, P.L.2    Hay-Schmidt, A.3    Mikkelsen, J.4    Shekhar, A.5
  • 3
    • 50849113451 scopus 로고    scopus 로고
    • Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease
    • doi: 10.1016/j.neubiorev.2008.03.006
    • Holmes A, (2008) Genetic variation in cortico-amygdala serotonin function and risk for stress-related disease. Neurosci Biobehav Rev 32: 1293-1314. doi:10.1016/j.neubiorev.2008.03.006. PubMed: 18439676.
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 1293-1314
    • Holmes, A.1
  • 4
    • 45849150032 scopus 로고    scopus 로고
    • Corticosteroid-serotonin interactions in the neurobiological mechanisms of stress-related disorders
    • doi: 10.1016/j.neubiorev.2008.04.006
    • Lanfumey L, Mongeau R, Cohen-Salmon C, Hamon M, (2008) Corticosteroid-serotonin interactions in the neurobiological mechanisms of stress-related disorders. Neurosci Biobehav Rev 32: 1174-1184. doi:10.1016/j.neubiorev.2008.04.006. PubMed: 18534678.
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 1174-1184
    • Lanfumey, L.1    Mongeau, R.2    Cohen-Salmon, C.3    Hamon, M.4
  • 5
    • 33846448741 scopus 로고    scopus 로고
    • Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice
    • doi: 10.1523/JNEUROSCI.4595-06.2007
    • Wellman CL, Izquierdo A, Garrett JE, Martin KP, Carroll J, et al. (2007) Impaired stress-coping and fear extinction and abnormal corticolimbic morphology in serotonin transporter knock-out mice. J Neurosci 27: 684-691. doi:10.1523/JNEUROSCI.4595-06.2007. PubMed: 17234600.
    • (2007) J Neurosci , vol.27 , pp. 684-691
    • Wellman, C.L.1    Izquierdo, A.2    Garrett, J.E.3    Martin, K.P.4    Carroll, J.5
  • 6
    • 0026419334 scopus 로고
    • Cloning and expression of a functional serotonin transporter from rat brain
    • doi: 10.1038/354066a0
    • Blakely RD, Berson HE, Fremeau RT, Caron MG, Peek MM, et al. (1991) Cloning and expression of a functional serotonin transporter from rat brain. Nature 354: 66-70. doi:10.1038/354066a0. PubMed: 1944572.
    • (1991) Nature , vol.354 , pp. 66-70
    • Blakely, R.D.1    Berson, H.E.2    Fremeau, R.T.3    Caron, M.G.4    Peek, M.M.5
  • 7
    • 79960782040 scopus 로고    scopus 로고
    • Social defeat: impact on fear extinction and amygdala-prefrontal cortical theta synchrony in 5-HTT deficient mice
    • doi: 10.1371/journal.pone.0022600
    • Narayanan V, Heiming RS, Jansen F, Lesting J, Sachser N, et al. (2011) Social defeat: impact on fear extinction and amygdala-prefrontal cortical theta synchrony in 5-HTT deficient mice. PLOS ONE 6: e22600. doi:10.1371/journal.pone.0022600. PubMed: 21818344.
    • (2011) PLOS ONE , vol.6
    • Narayanan, V.1    Heiming, R.S.2    Jansen, F.3    Lesting, J.4    Sachser, N.5
  • 8
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice
    • PubMed: 9547354
    • Bengel D, Murphy DL, Andrews AM, Wichems CH, Feltner D, et al. (1998) Altered brain serotonin homeostasis and locomotor insensitivity to 3, 4-methylenedioxymethamphetamine ("Ecstasy") in serotonin transporter-deficient mice. Mol Pharmacol 53: 649-655. PubMed: 9547354.
    • (1998) Mol Pharmacol , vol.53 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3    Wichems, C.H.4    Feltner, D.5
  • 9
    • 77952420169 scopus 로고    scopus 로고
    • Social status and day-to-day behaviour of male serotonin transporter knockout mice
    • doi: 10.1016/j.bbr.2010.03.035
    • Lewejohann L, Kloke V, Heiming RS, Jansen F, Kaiser S, et al. (2010) Social status and day-to-day behaviour of male serotonin transporter knockout mice. Behav Brain Res 211: 220-228. doi:10.1016/j.bbr.2010.03.035. PubMed: 20347882.
    • (2010) Behav Brain Res , vol.211 , pp. 220-228
    • Lewejohann, L.1    Kloke, V.2    Heiming, R.S.3    Jansen, F.4    Kaiser, S.5
  • 10
    • 73949134404 scopus 로고    scopus 로고
    • Adverse early life experience and social stress during adulthood interact to increase serotonin transporter mRNA expression
    • doi: 10.1016/j.brainres.2009.09.065
    • Gardner KL, Hale MW, Lightman SL, Plotsky PM, Lowry CA, (2009) Adverse early life experience and social stress during adulthood interact to increase serotonin transporter mRNA expression. Brain Res 1305: 47-63. doi:10.1016/j.brainres.2009.09.065. PubMed: 19781533.
    • (2009) Brain Res , vol.1305 , pp. 47-63
    • Gardner, K.L.1    Hale, M.W.2    Lightman, S.L.3    Plotsky, P.M.4    Lowry, C.A.5
  • 11
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • doi: 10.1126/science.274.5292.1527
    • Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, et al. (1996) Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274: 1527-1531. doi:10.1126/science.274.5292.1527. PubMed: 8929413.
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3    Sabol, S.Z.4    Greenberg, B.D.5
  • 12
    • 0031817660 scopus 로고    scopus 로고
    • Serotonin transporter and psychiatric disorders: Listening to the gene
    • doi: 10.1177/107385849800400110
    • Lesch K, (1998) Serotonin transporter and psychiatric disorders: Listening to the gene. Neuroscientist 4: 25-34. doi:10.1177/107385849800400110.
    • (1998) Neuroscientist , vol.4 , pp. 25-34
    • Lesch, K.1
  • 13
    • 34548314067 scopus 로고    scopus 로고
    • Long story short: the serotonin transporter in emotion regulation and social cognition
    • doi: 10.1038/nn1964
    • Canli T, Lesch K-P, (2007) Long story short: the serotonin transporter in emotion regulation and social cognition. Nat Neurosci 10: 1103-1109. doi:10.1038/nn1964. PubMed: 17726476.
    • (2007) Nat Neurosci , vol.10 , pp. 1103-1109
    • Canli, T.1    Lesch, K.-P.2
  • 14
    • 36448970079 scopus 로고    scopus 로고
    • Using immediate-early genes to map hippocampal subregional functions
    • doi: 10.1101/lm.698107
    • Kubik S, Miyashita T, Guzowski JF, (2007) Using immediate-early genes to map hippocampal subregional functions. Learn Mem 14: 758-770. doi:10.1101/lm.698107. PubMed: 18007019.
    • (2007) Learn Mem , vol.14 , pp. 758-770
    • Kubik, S.1    Miyashita, T.2    Guzowski, J.F.3
  • 15
    • 36749081743 scopus 로고    scopus 로고
    • Restraint-induced fra-2 and c-fos expression in the rat forebrain: Relationship to stress duration
    • doi: 10.1016/j.neuroscience.2007.09.013
    • Weinberg MS, Girotti M, Spencer RL, (2007) Restraint-induced fra-2 and c-fos expression in the rat forebrain: Relationship to stress duration. Neuroscience 150: 478-486. doi:10.1016/j.neuroscience.2007.09.013. PubMed: 17936518.
    • (2007) Neuroscience , vol.150 , pp. 478-486
    • Weinberg, M.S.1    Girotti, M.2    Spencer, R.L.3
  • 16
    • 0033915750 scopus 로고    scopus 로고
    • Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter
    • doi: 10.1046/j.1460-9568.2000.00126.x
    • Fabre V, Beaufour C, Evrard A, Rioux A, Hanoun N, et al. (2000) Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter. Eur J Neurosci 12: 2299-2310. doi:10.1046/j.1460-9568.2000.00126.x. PubMed: 10947809.
    • (2000) Eur J Neurosci , vol.12 , pp. 2299-2310
    • Fabre, V.1    Beaufour, C.2    Evrard, A.3    Rioux, A.4    Hanoun, N.5
  • 17
    • 5044225659 scopus 로고    scopus 로고
    • Regional Differences in Extracellular Dopamine and Serotonin Assessed by In Vivo Microdialysis in Mice Lacking Dopamine and/or Serotonin Transporters
    • doi: 10.1038/sj.npp.1300476
    • Shen H-W, Hagino Y, Kobayashi H, Shinohara-Tanaka K, Ikeda K, et al. (2004) Regional Differences in Extracellular Dopamine and Serotonin Assessed by In Vivo Microdialysis in Mice Lacking Dopamine and/or Serotonin Transporters. Neuropsychopharmacol 29: 1790-1799. doi:10.1038/sj.npp.1300476.
    • (2004) Neuropsychopharmacol , vol.29 , pp. 1790-1799
    • Shen, H.-W.1    Hagino, Y.2    Kobayashi, H.3    Shinohara-Tanaka, K.4    Ikeda, K.5
  • 18
    • 0023782359 scopus 로고
    • The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes
    • doi: 10.1016/0092-8674(88)90076-1
    • Chiu R, Boyle WJ, Meek J, Smeal T, Hunter T, et al. (1988) The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 54: 541-552. doi:10.1016/0092-8674(88)90076-1. PubMed: 3135940.
    • (1988) Cell , vol.54 , pp. 541-552
    • Chiu, R.1    Boyle, W.J.2    Meek, J.3    Smeal, T.4    Hunter, T.5
  • 19
    • 0037369530 scopus 로고    scopus 로고
    • Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice
    • doi: 10.1002/jnr.10521
    • Schmitt A, Mössner R, Gossmann A, Fischer IG, Gorboulev V, et al. (2003) Organic cation transporter capable of transporting serotonin is up-regulated in serotonin transporter-deficient mice. J Neurosci Res 71: 701-709. doi:10.1002/jnr.10521. PubMed: 12584728.
    • (2003) J Neurosci Res , vol.71 , pp. 701-709
    • Schmitt, A.1    Mössner, R.2    Gossmann, A.3    Fischer, I.G.4    Gorboulev, V.5
  • 20
    • 0024284824 scopus 로고
    • Common DNA binding site for Fos protein complexes and transcription factor AP-1
    • doi: 10.1016/S0092-8674(88)80039-4
    • Rauscher FJ, Sambucetti LC, Curran T, Distel RJ, Spiegelman BM, (1988) Common DNA binding site for Fos protein complexes and transcription factor AP-1. Cell 52: 471-480. doi:10.1016/S0092-8674(88)80039-4. PubMed: 3125983.
    • (1988) Cell , vol.52 , pp. 471-480
    • Rauscher, F.J.1    Sambucetti, L.C.2    Curran, T.3    Distel, R.J.4    Spiegelman, B.M.5
  • 21
    • 34548179797 scopus 로고    scopus 로고
    • Adult neurogenesis in serotonin transporter deficient mice
    • doi: 10.1007/s00702-007-0724-6
    • Schmitt A, Benninghoff J, Moessner R, Rizzi M, Paizanis E, et al. (2007) Adult neurogenesis in serotonin transporter deficient mice. J Neural Transm 114: 1107-1119. doi:10.1007/s00702-007-0724-6. PubMed: 17510734.
    • (2007) J Neural Transm , vol.114 , pp. 1107-1119
    • Schmitt, A.1    Benninghoff, J.2    Moessner, R.3    Rizzi, M.4    Paizanis, E.5
  • 22
    • 79751537041 scopus 로고    scopus 로고
    • Serotonin transporter knockout and repeated social defeat stress: impact on neuronal morphology and plasticity in limbic brain areas
    • doi: 10.1016/j.bbr.2011.01.011
    • Nietzer SL, Bonn M, Jansen F, Heiming RS, Lewejohann L, et al. (2011) Serotonin transporter knockout and repeated social defeat stress: impact on neuronal morphology and plasticity in limbic brain areas. Behav Brain Res 220: 42-54. doi:10.1016/j.bbr.2011.01.011. PubMed: 21238500.
    • (2011) Behav Brain Res , vol.220 , pp. 42-54
    • Nietzer, S.L.1    Bonn, M.2    Jansen, F.3    Heiming, R.S.4    Lewejohann, L.5
  • 23
    • 59649125580 scopus 로고    scopus 로고
    • Rapid Activation of Plasticity-Associated Gene Transcription in Hippocampal Neurons Provides a Mechanism for Encoding of One-Trial Experience
    • doi: 10.1523/JNEUROSCI.4588-08.2009
    • Miyashita T, Kubik S, Haghighi N, Steward O, Guzowski JF, (2009) Rapid Activation of Plasticity-Associated Gene Transcription in Hippocampal Neurons Provides a Mechanism for Encoding of One-Trial Experience. J Neurosci 29: 898-906. doi:10.1523/JNEUROSCI.4588-08.2009. PubMed: 19176799.
    • (2009) J Neurosci , vol.29 , pp. 898-906
    • Miyashita, T.1    Kubik, S.2    Haghighi, N.3    Steward, O.4    Guzowski, J.F.5
  • 24
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: insights into human neurobiology
    • doi: 10.1038/nrn2284
    • Murphy DL, Lesch K-P, (2008) Targeting the murine serotonin transporter: insights into human neurobiology. Nat Rev Neurosci 9: 85-96. doi:10.1038/nrn2284. PubMed: 18209729.
    • (2008) Nat Rev Neurosci , vol.9 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.-P.2
  • 25
    • 84878403211 scopus 로고    scopus 로고
    • Long-term decrease in immediate early gene expression after electroconvulsive seizures
    • doi: 10.1007/s00702-012-0861-4
    • Braga Calais J, Valvassori SS, Resende WR, Feier G, Athié MCP, et al. (2013) Long-term decrease in immediate early gene expression after electroconvulsive seizures. J Neural Transm 120: 259-266. doi:10.1007/s00702-012-0861-4. PubMed: 22875635.
    • (2013) J Neural Transm , vol.120 , pp. 259-266
    • Braga Calais, J.1    Valvassori, S.S.2    Resende, W.R.3    Feier, G.4    Athié, M.C.P.5
  • 26
    • 84874904480 scopus 로고    scopus 로고
    • Effect of acute stressor and serotonin transporter genotype on amygdala first wave transcriptome in mice
    • doi: 10.1371/journal.pone.0058880
    • Hohoff C, Gorji A, Kaiser S, Willscher E, Korsching E, et al. (2013) Effect of acute stressor and serotonin transporter genotype on amygdala first wave transcriptome in mice. PLOS ONE 8: e58880. doi:10.1371/journal.pone.0058880. PubMed: 23536833.
    • (2013) PLOS ONE , vol.8
    • Hohoff, C.1    Gorji, A.2    Kaiser, S.3    Willscher, E.4    Korsching, E.5
  • 27
    • 0242391960 scopus 로고    scopus 로고
    • Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression
    • doi: 10.1016/j.biopsych.2003.09.003
    • Holmes A, Murphy DL, Crawley JN, (2003) Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biol Psychiatry 54: 953-959. doi:10.1016/j.biopsych.2003.09.003. PubMed: 14625137.
    • (2003) Biol Psychiatry , vol.54 , pp. 953-959
    • Holmes, A.1    Murphy, D.L.2    Crawley, J.N.3
  • 28
    • 0028894469 scopus 로고
    • Pattern and time course of immediate early gene expression in rat brain following acute stress
    • doi: 10.1016/0306-4522(94)00355-9
    • Cullinan WE, Herman JP, Battaglia DF, Akil H, Watson SJ, (1995) Pattern and time course of immediate early gene expression in rat brain following acute stress. Neuroscience 64: 477-505. doi:10.1016/0306-4522(94)00355-9. PubMed: 7700534.
    • (1995) Neuroscience , vol.64 , pp. 477-505
    • Cullinan, W.E.1    Herman, J.P.2    Battaglia, D.F.3    Akil, H.4    Watson, S.J.5
  • 30
    • 0038413666 scopus 로고    scopus 로고
    • c-Fos expression in supramammillary and medial mammillary nuclei following spatial reference and working memory tasks
    • doi: 10.1016/S0031-9384(03)00060-X
    • Santín LJ, Aguirre JA, Rubio S, Begega A, Miranda R, et al. (2003) c-Fos expression in supramammillary and medial mammillary nuclei following spatial reference and working memory tasks. Physiol Behav 78: 733-739. doi:10.1016/S0031-9384(03)00060-X. PubMed: 12782230.
    • (2003) Physiol Behav , vol.78 , pp. 733-739
    • Santin, L.J.1    Aguirre, J.A.2    Rubio, S.3    Begega, A.4    Miranda, R.5
  • 31
    • 23744439526 scopus 로고    scopus 로고
    • Differential induction of c-Jun and Fos-like proteins in rat hippocampus and dorsal striatum after training in two water maze tasks
    • doi: 10.1016/j.nlm.2005.03.006
    • Teather LA, Packard MG, Smith DE, Ellis-Behnke RG, Bazan NG, (2005) Differential induction of c-Jun and Fos-like proteins in rat hippocampus and dorsal striatum after training in two water maze tasks. Neurobiol Learn Mem 84: 75-84. doi:10.1016/j.nlm.2005.03.006. PubMed: 15936959.
    • (2005) Neurobiol Learn Mem , vol.84 , pp. 75-84
    • Teather, L.A.1    Packard, M.G.2    Smith, D.E.3    Ellis-Behnke, R.G.4    Bazan, N.G.5
  • 32
    • 77952427750 scopus 로고    scopus 로고
    • Living in a dangerous world: the shaping of behavioral profile by early environment and 5-HTT genotype
    • doi: 10.3389/neuro.08.026.2009
    • Heiming RS, Jansen F, Lewejohann L, Kaiser S, Schmitt A, et al. (2009) Living in a dangerous world: the shaping of behavioral profile by early environment and 5-HTT genotype. Front. Behav Neurosci 3: 26. doi:10.3389/neuro.08.026.2009.
    • (2009) Front. Behav Neurosci , vol.3 , pp. 26
    • Heiming, R.S.1    Jansen, F.2    Lewejohann, L.3    Kaiser, S.4    Schmitt, A.5
  • 33
    • 84867744055 scopus 로고    scopus 로고
    • Differential BDNF signaling in dentate gyrus and perirhinal cortex during consolidation of recognition memory in the rat
    • doi: 10.1002/hipo.22033
    • Callaghan CK, Kelly ÁM, (2012) Differential BDNF signaling in dentate gyrus and perirhinal cortex during consolidation of recognition memory in the rat. Hippocampus 22: 2127-2135. doi:10.1002/hipo.22033. PubMed: 22573708.
    • (2012) Hippocampus , vol.22 , pp. 2127-2135
    • Callaghan, C.K.1    Kelly, ÁM.2
  • 34
    • 70649099131 scopus 로고    scopus 로고
    • Modulation of behavioural profile and stress response by 5-HTT genotype and social experience in adulthood
    • doi: 10.1016/j.bbr.2009.09.033
    • Jansen F, Heiming RS, Lewejohann L, Touma C, Palme R, et al. (2009) Modulation of behavioural profile and stress response by 5-HTT genotype and social experience in adulthood. Behav Brain Res, 207: 1-9. doi:10.1016/j.bbr.2009.09.033. PubMed: 19782704.
    • (2009) Behav Brain Res , vol.207 , pp. 1-9
    • Jansen, F.1    Heiming, R.S.2    Lewejohann, L.3    Touma, C.4    Palme, R.5
  • 35
    • 0029045938 scopus 로고
    • Chronic antidepressant treatment down-regulates the induction of c-fos mRNA in response to acute stress in rat frontal cortex
    • doi: 10.1016/0893-133X(94)00067-A
    • Morinobu S, Nibuya M, Duman RS, (1995) Chronic antidepressant treatment down-regulates the induction of c-fos mRNA in response to acute stress in rat frontal cortex. Neuropsychopharmacol 12: 221-228. doi:10.1016/0893-133X(94)00067-A. PubMed: 7612155.
    • (1995) Neuropsychopharmacol , vol.12 , pp. 221-228
    • Morinobu, S.1    Nibuya, M.2    Duman, R.S.3
  • 36
    • 0036106266 scopus 로고    scopus 로고
    • Tianeptine: 5-HT uptake sites and 5-HT 1-7 receptors modulate memory formation in an autoshaping Pavlovian/instrumental task
    • doi: 10.1016/S0149-7634(02)00005-2
    • Meneses A, (2002) Tianeptine: 5-HT uptake sites and 5-HT 1-7 receptors modulate memory formation in an autoshaping Pavlovian/instrumental task. Neurosci Biobehav Rev 26: 309-319. doi:10.1016/S0149-7634(02)00005-2. PubMed: 12034133.
    • (2002) Neurosci Biobehav Rev , vol.26 , pp. 309-319
    • Meneses, A.1
  • 37
    • 0029120572 scopus 로고
    • Chlordiazepoxide attenuates stress-induced activation of neurons, corticotropin-releasing factor (CRF) gene transcription and CRF biosynthesis in the paraventricular nucleus (PVN)
    • doi: 10.1016/0169-328X(95)00086-8
    • Imaki T, Xiao-Quan W, Shibasaki T, Harada S, Chikada N, et al. (1995) Chlordiazepoxide attenuates stress-induced activation of neurons, corticotropin-releasing factor (CRF) gene transcription and CRF biosynthesis in the paraventricular nucleus (PVN). Brain Res. Mol Brain Res 32: 261-270. doi:10.1016/0169-328X(95)00086-8. PubMed: 7500837.
    • (1995) Brain Res. Mol Brain Res , vol.32 , pp. 261-270
    • Imaki, T.1    Xiao-Quan, W.2    Shibasaki, T.3    Harada, S.4    Chikada, N.5
  • 38
    • 0142089973 scopus 로고    scopus 로고
    • Role of the Serotonin 5-HT2A Receptor in Learning
    • doi: 10.1101/lm.60803
    • Harvey JA, (2003) Role of the Serotonin 5-HT2A Receptor in Learning. Learn Mem 10: 355-362. doi:10.1101/lm.60803. PubMed: 14557608.
    • (2003) Learn Mem , vol.10 , pp. 355-362
    • Harvey, J.A.1
  • 39
    • 0032444348 scopus 로고    scopus 로고
    • Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
    • doi: 10.1016/S0165-0173(98)00018-6
    • Herdegen T, Leah JD, (1998) Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain. Res Rev 28: 370-490. doi:10.1016/S0165-0173(98)00018-6.
    • (1998) Brain. Res Rev , vol.28 , pp. 370-490
    • Herdegen, T.1    Leah, J.D.2
  • 41
    • 57349170839 scopus 로고    scopus 로고
    • Environmental novelty is associated with a selective increase in Fos expression in the output elements of the hippocampal formation and the perirhinal cortex
    • doi: 10.1101/lm.1196508
    • VanElzakker M, Fevurly RD, Breindel T, Spencer RL, (2008) Environmental novelty is associated with a selective increase in Fos expression in the output elements of the hippocampal formation and the perirhinal cortex. Learn Mem 15: 899-908. doi:10.1101/lm.1196508. PubMed: 19050162.
    • (2008) Learn Mem , vol.15 , pp. 899-908
    • VanElzakker, M.1    Fevurly, R.D.2    Breindel, T.3    Spencer, R.L.4
  • 42
    • 37049037491 scopus 로고    scopus 로고
    • The back and forth of dendritic plasticity
    • doi: 10.1016/j.neuron.2007.12.004
    • Williams SR, Wozny C, Mitchell SJ, (2007) The back and forth of dendritic plasticity. Neuron 56: 947-953. doi:10.1016/j.neuron.2007.12.004. PubMed: 18093518.
    • (2007) Neuron , vol.56 , pp. 947-953
    • Williams, S.R.1    Wozny, C.2    Mitchell, S.J.3
  • 43
    • 0028853459 scopus 로고
    • Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites
    • doi: 10.1016/0896-6273(95)90299-6
    • Lyford GL, Yamagata K, Kaufmann WE, Barnes CA, Sanders LK, et al. (1995) Arc, a growth factor and activity-regulated gene, encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites. Neuron 14: 433-445. doi:10.1016/0896-6273(95)90299-6. PubMed: 7857651.
    • (1995) Neuron , vol.14 , pp. 433-445
    • Lyford, G.L.1    Yamagata, K.2    Kaufmann, W.E.3    Barnes, C.A.4    Sanders, L.K.5
  • 44
    • 79952489924 scopus 로고    scopus 로고
    • Cognitive function is related to fronto-striatal serotonin transporter levels - a brain PET study in young healthy subjects
    • doi: 10.1007/s00213-010-1926-4
    • Madsen K, Erritzoe D, Mortensen EL, Gade A, Madsen J, et al. (2010) Cognitive function is related to fronto-striatal serotonin transporter levels - a brain PET study in young healthy subjects. Psychopharmacology 213: 573-581. doi:10.1007/s00213-010-1926-4. PubMed: 20623110.
    • (2010) Psychopharmacology , vol.213 , pp. 573-581
    • Madsen, K.1    Erritzoe, D.2    Mortensen, E.L.3    Gade, A.4    Madsen, J.5
  • 45
    • 0032191909 scopus 로고    scopus 로고
    • Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites
    • doi: 10.1016/S0896-6273(00)80591-7
    • Steward O, Wallace CS, Lyford GL, Worley PF, (1998) Synaptic activation causes the mRNA for the IEG Arc to localize selectively near activated postsynaptic sites on dendrites. Neuron 21: 741-751. doi:10.1016/S0896-6273(00)80591-7. PubMed: 9808461.
    • (1998) Neuron , vol.21 , pp. 741-751
    • Steward, O.1    Wallace, C.S.2    Lyford, G.L.3    Worley, P.F.4
  • 46
    • 68849130704 scopus 로고    scopus 로고
    • Serotonin transporter genotype is associated with cognitive performance but not regional 5-HT1A receptor binding in humans
    • doi: 10.1017/S1461145708009759
    • Borg J, Henningsson S, Saijo T, Inoue M, Bah J, et al. (2009) Serotonin transporter genotype is associated with cognitive performance but not regional 5-HT1A receptor binding in humans. Int J Neuropsychopharmacol 12: 783-792. doi:10.1017/S1461145708009759. PubMed: 19126263.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 783-792
    • Borg, J.1    Henningsson, S.2    Saijo, T.3    Inoue, M.4    Bah, J.5
  • 47
    • 20444434728 scopus 로고    scopus 로고
    • Long-term potentiation in the rat dentate gyrus is associated with enhanced Arc/Arg3. 1 protein expression in spines, dendrites and glia
    • doi: 10.1111/j.1460-9568.2005.04068.x
    • Rodríguez JJ, Davies HA, Silva AT, De Souza IE, Peddie CJ, et al. (2005) Long-term potentiation in the rat dentate gyrus is associated with enhanced Arc/Arg3. 1 protein expression in spines, dendrites and glia. Eur J Neurosci 21: 2384-2396. doi:10.1111/j.1460-9568.2005.04068.x. PubMed: 15932597.
    • (2005) Eur J Neurosci , vol.21 , pp. 2384-2396
    • Rodríguez, J.J.1    Davies, H.A.2    Silva, A.T.3    De Souza, I.E.4    Peddie, C.J.5
  • 48
    • 34250798553 scopus 로고    scopus 로고
    • The effects of acute tryptophan depletion and serotonin transporter polymorphism on emotional processing in memory and attention
    • doi: 10.1017/S146114570600705X
    • Roiser JP, Müller U, Clark L, Sahakian BJ, (2007) The effects of acute tryptophan depletion and serotonin transporter polymorphism on emotional processing in memory and attention. Int J Neuropsychopharmacol 10: 449-461. doi:10.1017/S146114570600705X. PubMed: 16893493.
    • (2007) Int J Neuropsychopharmacol , vol.10 , pp. 449-461
    • Roiser, J.P.1    Müller, U.2    Clark, L.3    Sahakian, B.J.4
  • 49
    • 36849024480 scopus 로고    scopus 로고
    • Genetic variation of serotonin function and cognitive control
    • doi: 10.1162/jocn.2007.19.12.1923
    • Strobel A, Dreisbach G, Müller J, Goschke T, Brocke B, et al. (2007) Genetic variation of serotonin function and cognitive control. J Cogn Neurosci 19: 1923-1931. doi:10.1162/jocn.2007.19.12.1923. PubMed: 17892388.
    • (2007) J Cogn Neurosci , vol.19 , pp. 1923-1931
    • Strobel, A.1    Dreisbach, G.2    Müller, J.3    Goschke, T.4    Brocke, B.5
  • 50
    • 33748525220 scopus 로고    scopus 로고
    • The effect of polymorphism at the serotonin transporter gene on decision-making, memory and executive function in ecstasy users and controls
    • doi: 10.1007/s00213-006-0495-z
    • Roiser JP, Rogers RD, Cook LJ, Sahakian BJ, (2006) The effect of polymorphism at the serotonin transporter gene on decision-making, memory and executive function in ecstasy users and controls. Psychopharmacology 188: 213-227. doi:10.1007/s00213-006-0495-z. PubMed: 16941121.
    • (2006) Psychopharmacology , vol.188 , pp. 213-227
    • Roiser, J.P.1    Rogers, R.D.2    Cook, L.J.3    Sahakian, B.J.4
  • 51
    • 0029046978 scopus 로고
    • Somatodendritic expression of an immediate early gene is regulated by synaptic activity
    • doi: 10.1073/pnas.92.12.5734
    • Link W, Konietzko U, Kauselmann G, Krug M, Schwanke B, et al. (1995) Somatodendritic expression of an immediate early gene is regulated by synaptic activity. Proc Natl Acad Sci U_S_A 92: 5734-5738. doi:10.1073/pnas.92.12.5734. PubMed: 7777577.
    • (1995) Proc Natl Acad Sci U_S_A , vol.92 , pp. 5734-5738
    • Link, W.1    Konietzko, U.2    Kauselmann, G.3    Krug, M.4    Schwanke, B.5
  • 52
    • 33745550771 scopus 로고    scopus 로고
    • AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc
    • doi: 10.1038/nn1708
    • Rao VR, Pintchovski SA, Chin J, Peebles CL, Mitra S, et al. (2006) AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc. Nat Neurosci 9: 887-895. doi:10.1038/nn1708. PubMed: 16732277.
    • (2006) Nat Neurosci , vol.9 , pp. 887-895
    • Rao, V.R.1    Pintchovski, S.A.2    Chin, J.3    Peebles, C.L.4    Mitra, S.5
  • 53
    • 0034213297 scopus 로고    scopus 로고
    • Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory
    • doi: 10818134
    • Guzowski JF, Lyford GL, Stevenson GD, Houston FP, McGaugh JL, et al. (2000) Inhibition of activity-dependent arc protein expression in the rat hippocampus impairs the maintenance of long-term potentiation and the consolidation of long-term memory. J Neurosci 20: 3993-4001. PubMed: 10818134.
    • (2000) J Neurosci , vol.20 , pp. 3993-4001
    • Guzowski, J.F.1    Lyford, G.L.2    Stevenson, G.D.3    Houston, F.P.4    McGaugh, J.L.5
  • 54
    • 77955978981 scopus 로고    scopus 로고
    • Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice
    • doi: 10.1093/cercor/bhp266
    • Brigman JL, Mathur P, Harvey-White J, Izquierdo A, Saksida LM, et al. (2010) Pharmacological or genetic inactivation of the serotonin transporter improves reversal learning in mice. Cereb Cortex 20: 1955-1963. doi:10.1093/cercor/bhp266. PubMed: 20032063.
    • (2010) Cereb Cortex , vol.20 , pp. 1955-1963
    • Brigman, J.L.1    Mathur, P.2    Harvey-White, J.3    Izquierdo, A.4    Saksida, L.M.5
  • 55
    • 33750496896 scopus 로고    scopus 로고
    • Arc/Arg3. 1 is essential for the consolidation of synaptic plasticity and memories
    • doi: 10.1016/j.neuron.2006.08.024
    • Plath N, Ohana O, Dammermann B, Errington ML, Schmitz D, et al. (2006) Arc/Arg3. 1 is essential for the consolidation of synaptic plasticity and memories. Neuron 52: 437-444. doi:10.1016/j.neuron.2006.08.024. PubMed: 17088210.
    • (2006) Neuron , vol.52 , pp. 437-444
    • Plath, N.1    Ohana, O.2    Dammermann, B.3    Errington, M.L.4    Schmitz, D.5
  • 56
    • 77951880720 scopus 로고    scopus 로고
    • Cognitive impact of genetic variation of the serotonin transporter in primates is associated with differences in brain morphology rather than serotonin neurotransmission
    • doi: 10.1038/mp.2009.90
    • Jedema HP, Gianaros PJ, Greer PJ, Kerr DD, Liu S, et al. (2010) Cognitive impact of genetic variation of the serotonin transporter in primates is associated with differences in brain morphology rather than serotonin neurotransmission. Mol Psychiatry 15: 512-22-446. doi:10.1038/mp.2009.90. PubMed: 19721434.
    • (2010) Mol Psychiatry , vol.15 , pp. 446-512
    • Jedema, H.P.1    Gianaros, P.J.2    Greer, P.J.3    Kerr, D.D.4    Liu, S.5
  • 57
    • 34848919232 scopus 로고    scopus 로고
    • Sustained Arc/Arg3.1 Synthesis Controls Long-Term Potentiation Consolidation through Regulation of Local Actin Polymerization in the Dentate Gyrus In Vivo
    • doi: 10.1523/JNEUROSCI.2883-07.2007
    • Messaoudi E, Kanhema T, Soulé J, Tiron A, Dagyte G, et al. (2007) Sustained Arc/Arg3.1 Synthesis Controls Long-Term Potentiation Consolidation through Regulation of Local Actin Polymerization in the Dentate Gyrus In Vivo. J Neurosci 27: 10445-10455. doi:10.1523/JNEUROSCI.2883-07.2007. PubMed: 17898216.
    • (2007) J Neurosci , vol.27 , pp. 10445-10455
    • Messaoudi, E.1    Kanhema, T.2    Soulé, J.3    Tiron, A.4    Dagyte, G.5
  • 58
    • 34848849006 scopus 로고    scopus 로고
    • Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility
    • doi: 10.1111/j.1460-9568.2007.05839.x
    • Homberg JR, Pattij T, Janssen MCW, Ronken E, De Boer SF, et al. (2007) Serotonin transporter deficiency in rats improves inhibitory control but not behavioural flexibility. Eur J Neurosci 26: 2066-2073. doi:10.1111/j.1460-9568.2007.05839.x. PubMed: 17897403.
    • (2007) Eur J Neurosci , vol.26 , pp. 2066-2073
    • Homberg, J.R.1    Pattij, T.2    Janssen, M.C.W.3    Ronken, E.4    De Boer, S.F.5
  • 59
    • 0142154251 scopus 로고    scopus 로고
    • Antidepressant drug treatment induces Arc gene expression in the rat brain
    • doi: 10.1016/S0306-4522(03)00504-9
    • Pei Q, Zetterström TSC, Sprakes M, Tordera R, Sharp T, (2003) Antidepressant drug treatment induces Arc gene expression in the rat brain. Neuroscience 121: 975-982. doi:10.1016/S0306-4522(03)00504-9. PubMed: 14580947.
    • (2003) Neuroscience , vol.121 , pp. 975-982
    • Pei, Q.1    Zetterström, T.S.C.2    Sprakes, M.3    Tordera, R.4    Sharp, T.5
  • 60
    • 84876672793 scopus 로고    scopus 로고
    • Early life stress-induced histone acetylations correlate with activation of the synaptic plasticity genes Arc and Egr1 in the mouse hippocampus
    • doi: 10.1111/jnc.12210
    • Xie L, Korkmaz KS, Braun K, Bock J, (2013) Early life stress-induced histone acetylations correlate with activation of the synaptic plasticity genes Arc and Egr1 in the mouse hippocampus. J Neurochem 125: 457-464. doi:10.1111/jnc.12210. PubMed: 23413876.
    • (2013) J Neurochem , vol.125 , pp. 457-464
    • Xie, L.1    Korkmaz, K.S.2    Braun, K.3    Bock, J.4
  • 61
    • 84879595525 scopus 로고    scopus 로고
    • A role for the extended amygdala in the fear-enhancing effects of acute selective serotonin reuptake inhibitor treatment
    • doi: 10.1038/tp.2012.137
    • Ravinder S, Burghardt NS, Brodsky R, Bauer EP, Chattarji S, (2013) A role for the extended amygdala in the fear-enhancing effects of acute selective serotonin reuptake inhibitor treatment. Transl Psychiatry 3: e209. doi:10.1038/tp.2012.137. PubMed: 23321806.
    • (2013) Transl Psychiatry , vol.3
    • Ravinder, S.1    Burghardt, N.S.2    Brodsky, R.3    Bauer, E.P.4    Chattarji, S.5
  • 62
    • 0026847039 scopus 로고
    • Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans
    • doi: 10.1037/0033-295X.99.2.195
    • Squire LR, (1992) Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol Rev 99: 195-231. doi:10.1037/0033-295X.99.2.195. PubMed: 1594723.
    • (1992) Psychol Rev , vol.99 , pp. 195-231
    • Squire, L.R.1
  • 63
    • 0027492237 scopus 로고
    • The hippocampus and spatial memory
    • doi: 10.1016/0166-2236(93)90016-F
    • Squire LR, (1993) The hippocampus and spatial memory. Trends Neurosci 16: 56-57. doi:10.1016/0166-2236(93)90016-F. PubMed: 7680500.
    • (1993) Trends Neurosci , vol.16 , pp. 56-57
    • Squire, L.R.1
  • 64
    • 5144223971 scopus 로고    scopus 로고
    • Spatial memory, recognition memory, and the hippocampus
    • doi: 10.1073/pnas.0406344101
    • Broadbent NJ, Squire LR, Clark RE, (2004) Spatial memory, recognition memory, and the hippocampus. Proc Natl Acad Sci U_S_A 101: 14515-14520. doi:10.1073/pnas.0406344101. PubMed: 15452348.
    • (2004) Proc Natl Acad Sci U_S_A , vol.101 , pp. 14515-14520
    • Broadbent, N.J.1    Squire, L.R.2    Clark, R.E.3
  • 65
    • 0030726596 scopus 로고    scopus 로고
    • Stress-induced expression of immediate early genes in the brain and peripheral organs of the rat
    • doi: 10.1016/S0168-0102(97)00095-3
    • Senba E, Ueyama T, (1997) Stress-induced expression of immediate early genes in the brain and peripheral organs of the rat. Neurosci Res 29: 183-207. doi:10.1016/S0168-0102(97)00095-3. PubMed: 9436645.
    • (1997) Neurosci Res , vol.29 , pp. 183-207
    • Senba, E.1    Ueyama, T.2
  • 66
    • 0001159822 scopus 로고
    • Are New Neurons Formed in Brains of Adult Mammals
    • doi: 10.1126/science.135.3509.1127
    • Altman J, (1962) Are New Neurons Formed in Brains of Adult Mammals. Science 135: 1127-1128. doi:10.1126/science.135.3509.1127. PubMed: 13860748.
    • (1962) Science , vol.135 , pp. 1127-1128
    • Altman, J.1
  • 67
    • 0025088801 scopus 로고
    • Migration and Distribution of 2 Populations of Hippocampal Granule Cell Precursors during the Perinatal and Postnatal Periods
    • doi: 10.1002/cne.903010304
    • Altman J, Bayer SA, (1990) Migration and Distribution of 2 Populations of Hippocampal Granule Cell Precursors during the Perinatal and Postnatal Periods. J Comp Neurol 301: 365-381. doi:10.1002/cne.903010304. PubMed: 2262596.
    • (1990) J Comp Neurol , vol.301 , pp. 365-381
    • Altman, J.1    Bayer, S.A.2
  • 68
    • 0013855185 scopus 로고
    • Post-natal origin of microneurones in the rat brain
    • doi: 10.1038/207953a0
    • Altman J, Das GD, (1965) Post-natal origin of microneurones in the rat brain. Nature 207: 953-956. doi:10.1038/207953a0. PubMed: 5886931.
    • (1965) Nature , vol.207 , pp. 953-956
    • Altman, J.1    Das, G.D.2
  • 69
    • 0035845545 scopus 로고    scopus 로고
    • Adult-generated hippocampal and neocortical neurons in macaques have a transient existence
    • doi: 10.1073/pnas.181354698
    • Gould E, Vail N, Wagers M, Gross CG, (2001) Adult-generated hippocampal and neocortical neurons in macaques have a transient existence. Proc Natl Acad Sci U_S_A 98: 10910-10917. doi:10.1073/pnas.181354698. PubMed: 11526209.
    • (2001) Proc Natl Acad Sci U_S_A , vol.98 , pp. 10910-10917
    • Gould, E.1    Vail, N.2    Wagers, M.3    Gross, C.G.4
  • 70
    • 0032721988 scopus 로고    scopus 로고
    • Stress and hippocampal neurogenesis
    • doi: 10.1016/S0006-3223(99)00247-4
    • Gould E, Tanapat P, (1999) Stress and hippocampal neurogenesis. Biol Psychiatry 46: 1472-1479. doi:10.1016/S0006-3223(99)00247-4. PubMed: 10599477.
    • (1999) Biol Psychiatry , vol.46 , pp. 1472-1479
    • Gould, E.1    Tanapat, P.2
  • 71
    • 1642499190 scopus 로고    scopus 로고
    • Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible
    • doi: 10.1046/j.1460-9568.2003.03100.x
    • Heine VM, Maslam S, Zareno J, Joëls M, Lucassen PJ, (2004) Suppressed proliferation and apoptotic changes in the rat dentate gyrus after acute and chronic stress are reversible. Eur J Neurosci 19: 131-144. doi:10.1046/j.1460-9568.2003.03100.x. PubMed: 14750971.
    • (2004) Eur J Neurosci , vol.19 , pp. 131-144
    • Heine, V.M.1    Maslam, S.2    Zareno, J.3    Joëls, M.4    Lucassen, P.J.5
  • 72
    • 84880056448 scopus 로고    scopus 로고
    • Major depression: a role for hippocampal neurogenesis?
    • doi: 10.1007/7854_2012_226
    • Lee MM, Reif A, Schmitt AG, (2013) Major depression: a role for hippocampal neurogenesis? Curr Top. Behav Neurosci 14: 153-179. doi:10.1007/7854_2012_226.
    • (2013) Curr Top. Behav Neurosci , vol.14 , pp. 153-179
    • Lee, M.M.1    Reif, A.2    Schmitt, A.G.3
  • 73
    • 0032819263 scopus 로고    scopus 로고
    • Serotonin and Hippocampal Neurogenesis
    • doi: 10.1016/S0893-133X(99)00045-7
    • Gould E, (1999) Serotonin and Hippocampal Neurogenesis. Neuropsychopharmacol 21: 46S-51S. doi:10.1016/S0893-133X(99)00045-7. PubMed: 10432488.
    • (1999) Neuropsychopharmacol , vol.21
    • Gould, E.1
  • 74
    • 0033363319 scopus 로고    scopus 로고
    • Learning enhances adult neurogenesis in the hippocampal formation
    • doi: 10.1038/6365
    • Gould E, Beylin A, Tanapat P, Reeves AJ, Shors TJ, (1999) Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci 2: 260-265. doi:10.1038/6365. PubMed: 10195219.
    • (1999) Nat Neurosci , vol.2 , pp. 260-265
    • Gould, E.1    Beylin, A.2    Tanapat, P.3    Reeves, A.J.4    Shors, T.J.5
  • 75
    • 34548249099 scopus 로고    scopus 로고
    • Spatial learning depends on both the addition and removal of new hippocampal neurons
    • doi: 10.1371/journal.pbio.0050214
    • Dupret D, Fabre A, Döbrössy MD, Panatier A, Rodríguez JJ, et al. (2007) Spatial learning depends on both the addition and removal of new hippocampal neurons. PLOS Biol 5: e214. doi:10.1371/journal.pbio.0050214. PubMed: 17683201.
    • (2007) PLOS Biol , vol.5
    • Dupret, D.1    Fabre, A.2    Döbrössy, M.D.3    Panatier, A.4    Rodríguez, J.J.5
  • 76
    • 58549116696 scopus 로고    scopus 로고
    • Endogenous anxiety and stress responses in water maze and Barnes maze spatial memory tasks
    • doi: 10.1016/j.bbr.2008.10.015
    • Harrison FE, Hosseini AH, McDonald MP, (2009) Endogenous anxiety and stress responses in water maze and Barnes maze spatial memory tasks. Behav Brain Res 198: 247-251. doi:10.1016/j.bbr.2008.10.015. PubMed: 18996418.
    • (2009) Behav Brain Res , vol.198 , pp. 247-251
    • Harrison, F.E.1    Hosseini, A.H.2    McDonald, M.P.3
  • 77
    • 0028947694 scopus 로고
    • Stress and cognitive function
    • doi: 10.1016/0959-4388(95)80028-X
    • McEwen BS, Sapolsky RM, (1995) Stress and cognitive function. Curr Opin Neurobiol 5: 205-216. doi:10.1016/0959-4388(95)80028-X. PubMed: 7620309.
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 205-216
    • McEwen, B.S.1    Sapolsky, R.M.2
  • 78
    • 0035103864 scopus 로고    scopus 로고
    • Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders
    • doi: 10.1002/hup.266
    • McEwen BS, Magarinos AM, (2001) Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders. Hum Psychopharmacol 16: S7-S19. doi:10.1002/hup.266. PubMed: 12404531.
    • (2001) Hum Psychopharmacol , vol.16
    • McEwen, B.S.1    Magarinos, A.M.2
  • 79
    • 0033215376 scopus 로고    scopus 로고
    • Stress and cognition: are corticosteroids good or bad guys?
    • doi: 10.1016/S0166-2236(99)01438-1
    • de Kloet ER, Oitzl MS, Joëls M, (1999) Stress and cognition: are corticosteroids good or bad guys? Trends Neurosci 22: 422-426. doi:10.1016/S0166-2236(99)01438-1. PubMed: 10481183.
    • (1999) Trends Neurosci , vol.22 , pp. 422-426
    • de Kloet, E.R.1    Oitzl, M.S.2    Joëls, M.3
  • 80
    • 0032716595 scopus 로고    scopus 로고
    • 5-HT system and cognition
    • doi: 10.1016/S0149-7634(99)00067-6
    • Meneses A, (1999) 5-HT system and cognition. Neurosci Biobehav Rev 23: 1111-1125. doi:10.1016/S0149-7634(99)00067-6. PubMed: 10643820.
    • (1999) Neurosci Biobehav Rev , vol.23 , pp. 1111-1125
    • Meneses, A.1
  • 81
    • 0018344553 scopus 로고
    • Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat
    • doi: 10.1037/h0077579
    • Barnes CA, (1979) Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat. J Comp Physiol Psychol 93: 74-104. doi:10.1037/h0077579. PubMed: 221551.
    • (1979) J Comp Physiol Psychol , vol.93 , pp. 74-104
    • Barnes, C.A.1
  • 82
    • 57649225037 scopus 로고    scopus 로고
    • Digital image processing in behavioral sciences
    • Lewejohann L, (2004) Digital image processing in behavioral sciences.
    • (2004)
    • Lewejohann, L.1
  • 83
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • doi: 10.1016/0165-0270(84)90007-4
    • Morris R, (1984) Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 11: 47-60. doi:10.1016/0165-0270(84)90007-4. PubMed: 6471907.
    • (1984) J Neurosci Methods , vol.11 , pp. 47-60
    • Morris, R.1
  • 85
    • 84872593722 scopus 로고    scopus 로고
    • To attack, or not to attack? The role of serotonin transporter genotype in the display of maternal aggression
    • doi: 10.1016/j.bbr.2012.12.045
    • Heiming RS, Mönning A, Jansen F, Kloke V, Lesch KP, et al. (2013) To attack, or not to attack? The role of serotonin transporter genotype in the display of maternal aggression. Behav Brain Res 242: 135-141. doi:10.1016/j.bbr.2012.12.045. PubMed: 23291155.
    • (2013) Behav Brain Res , vol.242 , pp. 135-141
    • Heiming, R.S.1    Mönning, A.2    Jansen, F.3    Kloke, V.4    Lesch, K.P.5
  • 86
    • 0036897940 scopus 로고    scopus 로고
    • Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter
    • doi: 10.1016/S0893-133X(02)00374-3
    • Holmes A, Yang RJ, Murphy DL, Crawley JN, (2002) Evaluation of antidepressant-related behavioral responses in mice lacking the serotonin transporter. Neuropsychopharmacol 27: 914-923. doi:10.1016/S0893-133X(02)00374-3. PubMed: 12464448.
    • (2002) Neuropsychopharmacol , vol.27 , pp. 914-923
    • Holmes, A.1    Yang, R.J.2    Murphy, D.L.3    Crawley, J.N.4
  • 87
    • 33748375576 scopus 로고    scopus 로고
    • Are serotonin transporter knockout mice depressed?: hypoactivity but no anhedonia
    • doi: 10.1097/01.wnr.0000230514.08962.76, Retrieved onpublished at whilst December year 1111 from
    • Kalueff AV, Gallagher PS, Murphy DL, (2006) Are serotonin transporter knockout mice depressed?: hypoactivity but no anhedonia. Neuroreport 17: 1347-1351. Retrieved onpublished at whilst December year 1111 from. doi:10.1097/01.wnr.0000230514.08962.76.
    • (2006) Neuroreport , vol.17 , pp. 1347-1351
    • Kalueff, A.V.1    Gallagher, P.S.2    Murphy, D.L.3
  • 88
    • 34249065202 scopus 로고    scopus 로고
    • Hypolocomotion, anxiety and serotonin syndrome-like behavior contribute to the complex phenotype of serotonin transporter knockout mice
    • doi: 10.1111/j.1601-183X.2006.00270.x
    • Kalueff AV, Fox MA, Gallagher PS, Murphy DL, (2007) Hypolocomotion, anxiety and serotonin syndrome-like behavior contribute to the complex phenotype of serotonin transporter knockout mice. Genes Brain Behav 6: 389-400. doi:10.1111/j.1601-183X.2006.00270.x. PubMed: 16939636.
    • (2007) Genes Brain Behav , vol.6 , pp. 389-400
    • Kalueff, A.V.1    Fox, M.A.2    Gallagher, P.S.3    Murphy, D.L.4
  • 89
    • 77950862350 scopus 로고    scopus 로고
    • Lack of the serotonin transporter in mice reduces locomotor activity and leads to gender-dependent late onset obesity
    • doi: 10.1038/ijo.2009.289
    • Üçeyler N, Schütt M, Palm F, Vogel C, Meier M, et al. (2010) Lack of the serotonin transporter in mice reduces locomotor activity and leads to gender-dependent late onset obesity. Int J Obes Relat Metab Disord 34: 701-711. doi:10.1038/ijo.2009.289. PubMed: 20084070.
    • (2010) Int J Obes Relat Metab Disord , vol.34 , pp. 701-711
    • Üçeyler, N.1    Schütt, M.2    Palm, F.3    Vogel, C.4    Meier, M.5
  • 90
    • 0018763594 scopus 로고
    • Animal model of depression
    • PubMed: 573643
    • Porsolt RD, (1979) Animal model of depression. Biomedicine 30: 139-140. PubMed: 573643.
    • (1979) Biomedicine , vol.30 , pp. 139-140
    • Porsolt, R.D.1
  • 91
    • 33846408289 scopus 로고    scopus 로고
    • Effects of mild early life stress on abnormal emotion-related behaviors in 5-HTT knockout mice
    • doi: 10.1007/s10519-006-9129-9
    • Carroll JC, Boyce-Rustay JM, Millstein R, Yang R, Wiedholz LM, et al. (2007) Effects of mild early life stress on abnormal emotion-related behaviors in 5-HTT knockout mice. Behav Genet 37: 214-222. doi:10.1007/s10519-006-9129-9. PubMed: 17177116.
    • (2007) Behav Genet , vol.37 , pp. 214-222
    • Carroll, J.C.1    Boyce-Rustay, J.M.2    Millstein, R.3    Yang, R.4    Wiedholz, L.M.5
  • 92
    • 62749117195 scopus 로고    scopus 로고
    • Mice lacking brain-type creatine kinase activity show defective thermoregulation
    • doi: 10.1016/j.physbeh.2009.02.003
    • Streijger F, Pluk H, Oerlemans F, Beckers G, Bianco AC, et al. (2009) Mice lacking brain-type creatine kinase activity show defective thermoregulation. Physiol Behav 97: 76-86. doi:10.1016/j.physbeh.2009.02.003. PubMed: 19419668.
    • (2009) Physiol Behav , vol.97 , pp. 76-86
    • Streijger, F.1    Pluk, H.2    Oerlemans, F.3    Beckers, G.4    Bianco, A.C.5
  • 93
    • 0037741922 scopus 로고    scopus 로고
    • Hypothermia in mice tested in Morris water maze
    • doi: 10.1016/S0166-4328(02)00369-8
    • Iivonen H, Nurminen L, Harri M, Tanila H, Puoliväli J, (2003) Hypothermia in mice tested in Morris water maze. Behav Brain Res 141: 207-213. doi:10.1016/S0166-4328(02)00369-8. PubMed: 12742257.
    • (2003) Behav Brain Res , vol.141 , pp. 207-213
    • Iivonen, H.1    Nurminen, L.2    Harri, M.3    Tanila, H.4    Puoliväli, J.5
  • 94
    • 17144461569 scopus 로고    scopus 로고
    • Stress impairs performance in spatial water maze learning tasks
    • doi: 10.1016/S0166-4328(98)00134-X
    • Hölscher C, (1999) Stress impairs performance in spatial water maze learning tasks. Behav Brain Res 100: 225-235. doi:10.1016/S0166-4328(98)00134-X. PubMed: 10212070.
    • (1999) Behav Brain Res , vol.100 , pp. 225-235
    • Hölscher, C.1
  • 95
    • 0032706095 scopus 로고    scopus 로고
    • Reduction of 5-hydroxytryptamine (5-HT) 1A-mediated temperature and neuroendocrine responses and 5-HT1A binding sites in 5-HT transporter knockout mice
    • doi: 10565817
    • Li Q, Wichems C, Heils A, Van de Kar LD, Lesch KP, et al. (1999) Reduction of 5-hydroxytryptamine (5-HT) 1A-mediated temperature and neuroendocrine responses and 5-HT1A binding sites in 5-HT transporter knockout mice. J Pharmacol Exp Ther 291: 999-1007. PubMed: 10565817.
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 999-1007
    • Li, Q.1    Wichems, C.2    Heils, A.3    Van de Kar, L.D.4    Lesch, K.P.5
  • 96
    • 59249089847 scopus 로고    scopus 로고
    • Impaired hypothalamic-pituitary-adrenal axis and its feedback regulation in serotonin transporter knockout mice
    • doi: 10.1016/j.psyneuen.2008.09.011
    • Jiang X, Wang J, Luo T, Li Q, (2009) Impaired hypothalamic-pituitary-adrenal axis and its feedback regulation in serotonin transporter knockout mice. Psychoneuroendocrinology 34: 317-331. doi:10.1016/j.psyneuen.2008.09.011. PubMed: 18980809.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. 317-331
    • Jiang, X.1    Wang, J.2    Luo, T.3    Li, Q.4
  • 97
    • 0242574256 scopus 로고    scopus 로고
    • The Serotonin Transporter is Required for Stress-Evoked Increases in Adrenal Catecholamine Synthesis and Angiotensin II AT2 Receptor Expression
    • doi: 10.1159/000073705
    • Armando I, Tjurmina OA, Li Q, Murphy DL, Saavedra JM, (2003) The Serotonin Transporter is Required for Stress-Evoked Increases in Adrenal Catecholamine Synthesis and Angiotensin II AT2 Receptor Expression. Neuroendocrinology 78: 217-225. doi:10.1159/000073705. PubMed: 14583654.
    • (2003) Neuroendocrinology , vol.78 , pp. 217-225
    • Armando, I.1    Tjurmina, O.A.2    Li, Q.3    Murphy, D.L.4    Saavedra, J.M.5
  • 98
    • 0036892142 scopus 로고    scopus 로고
    • Exaggerated Adrenomedullary Response to Immobilization in Mice with Targeted Disruption of the Serotonin Transporter Gene
    • doi: 10.1210/en.2002-220416
    • Tjurmina OA, (2002) Exaggerated Adrenomedullary Response to Immobilization in Mice with Targeted Disruption of the Serotonin Transporter Gene. Endocrinology 143: 4520-4526. doi:10.1210/en.2002-220416. PubMed: 12446578.
    • (2002) Endocrinology , vol.143 , pp. 4520-4526
    • Tjurmina, O.A.1
  • 99
    • 3242666038 scopus 로고    scopus 로고
    • Life-long serotonin reuptake deficiency results in complex alterations in adrenomedullary responses to stress
    • doi: 10.1196/annals.1296.011
    • Tjurmina OA, Armando I, Saavedra JM, Li Q, Murphy DL, (2004) Life-long serotonin reuptake deficiency results in complex alterations in adrenomedullary responses to stress. Ann N Y Acad Sci 1018: 99-104. doi:10.1196/annals.1296.011. PubMed: 15240357.
    • (2004) Ann N Y Acad Sci , vol.1018 , pp. 99-104
    • Tjurmina, O.A.1    Armando, I.2    Saavedra, J.M.3    Li, Q.4    Murphy, D.L.5
  • 100
    • 77954836904 scopus 로고    scopus 로고
    • Increased vulnerability to psychosocial stress in heterozygous serotonin transporter knockout mice
    • doi: 10.1242/dmm.004614
    • Bartolomucci A, Carola V, Pascucci T, Puglisi-Allegra S, Cabib S, et al. (2010) Increased vulnerability to psychosocial stress in heterozygous serotonin transporter knockout mice. Dis Model. J Mech 3: 459-470. doi:10.1242/dmm.004614.
    • (2010) Dis Model. J Mech , vol.3 , pp. 459-470
    • Bartolomucci, A.1    Carola, V.2    Pascucci, T.3    Puglisi-Allegra, S.4    Cabib, S.5
  • 101
    • 0037135137 scopus 로고    scopus 로고
    • Serotonin transporter genetic variation and the response of the human amygdala
    • doi: 10.1126/science.1071829
    • Hariri AR, Mattay VS, Tessitore A, Kolachana B, Fera F, et al. (2002) Serotonin transporter genetic variation and the response of the human amygdala. Science 297: 400-403. doi:10.1126/science.1071829. PubMed: 12130784.
    • (2002) Science , vol.297 , pp. 400-403
    • Hariri, A.R.1    Mattay, V.S.2    Tessitore, A.3    Kolachana, B.4    Fera, F.5
  • 102
    • 34548182366 scopus 로고    scopus 로고
    • Human 5-HT transporter availability predicts amygdala reactivity in vivo
    • doi: 10.1523/JNEUROSCI.1175-07.2007
    • Rhodes RA, Murthy NV, Dresner MA, Selvaraj S, Stavrakakis N, et al. (2007) Human 5-HT transporter availability predicts amygdala reactivity in vivo. J Neurosci 27: 9233-9237. doi:10.1523/JNEUROSCI.1175-07.2007. PubMed: 17715358.
    • (2007) J Neurosci , vol.27 , pp. 9233-9237
    • Rhodes, R.A.1    Murthy, N.V.2    Dresner, M.A.3    Selvaraj, S.4    Stavrakakis, N.5
  • 103
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • doi: 10.1126/science.1083968
    • Caspi A, Sugden K, Moffitt TE, Taylor A, Craig IW, et al. (2003) Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene. Science 301: 386-389. doi:10.1126/science.1083968. PubMed: 12869766.
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3    Taylor, A.4    Craig, I.W.5
  • 104
    • 85047697355 scopus 로고    scopus 로고
    • Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression
    • doi: 10.1176/appi.ajp.163.9.1588
    • Zalsman G, Huang Y-Y, Oquendo MA, Burke AK, Hu X-Z, et al. (2006) Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression. Am J Psychiatry 163: 1588-1593. doi:10.1176/appi.ajp.163.9.1588. PubMed: 16946185.
    • (2006) Am J Psychiatry , vol.163 , pp. 1588-1593
    • Zalsman, G.1    Huang, Y.-Y.2    Oquendo, M.A.3    Burke, A.K.4    Hu, X.-Z.5
  • 105
    • 0035879067 scopus 로고    scopus 로고
    • Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genesArc, c-fos, and zif268
    • PubMed: 11438584
    • Guzowski JF, Setlow B, Wagner EK, McGaugh JL, (2001) Experience-dependent gene expression in the rat hippocampus after spatial learning: a comparison of the immediate-early genesArc, c-fos, and zif268. J Neurosci 21: 5089-5098. PubMed: 11438584.
    • (2001) J Neurosci , vol.21 , pp. 5089-5098
    • Guzowski, J.F.1    Setlow, B.2    Wagner, E.K.3    McGaugh, J.L.4
  • 106
    • 0033787523 scopus 로고    scopus 로고
    • Differential learning-stage dependent patterns of c-Fos protein expression in brain regions during the acquisition and memory consolidation of an operant task in mice
    • doi: 10.1046/j.1460-9568.2000.00258.x
    • Bertaina-Anglade V, Tramu G, Destrade C, (2000) Differential learning-stage dependent patterns of c-Fos protein expression in brain regions during the acquisition and memory consolidation of an operant task in mice. Eur J Neurosci 12: 3803-3812. doi:10.1046/j.1460-9568.2000.00258.x. PubMed: 11029651.
    • (2000) Eur J Neurosci , vol.12 , pp. 3803-3812
    • Bertaina-Anglade, V.1    Tramu, G.2    Destrade, C.3
  • 107
    • 0031963435 scopus 로고    scopus 로고
    • Differential intracellular sorting of immediate early gene mRNAs depends on signals in the mRNA sequence
    • PubMed: 9412483
    • Wallace CS, Lyford GL, Worley PF, Steward O, (1998) Differential intracellular sorting of immediate early gene mRNAs depends on signals in the mRNA sequence. J Neurosci 18: 26-35. PubMed: 9412483.
    • (1998) J Neurosci , vol.18 , pp. 26-35
    • Wallace, C.S.1    Lyford, G.L.2    Worley, P.F.3    Steward, O.4
  • 108
    • 70350417828 scopus 로고    scopus 로고
    • Altered expression and modulation of activity-regulated cytoskeletal associated protein (Arc) in serotonin transporter knockout rats
    • doi: 10.1016/j.euroneuro.2009.06.008
    • Molteni R, Calabrese F, Maj PF, Olivier JDA, Racagni G, et al. (2009) Altered expression and modulation of activity-regulated cytoskeletal associated protein (Arc) in serotonin transporter knockout rats. Eur Neuropsychopharmacol 19: 898-904. doi:10.1016/j.euroneuro.2009.06.008. PubMed: 19576731.
    • (2009) Eur Neuropsychopharmacol , vol.19 , pp. 898-904
    • Molteni, R.1    Calabrese, F.2    Maj, P.F.3    Olivier, J.D.A.4    Racagni, G.5
  • 109
    • 84856223404 scopus 로고    scopus 로고
    • Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration
    • doi: 10.1038/mp.2010.131
    • Eriksson TM, Delagrange P, Spedding M, Popoli M, Mathé AA, et al. (2012) Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration. Mol Psychiatry 17: 173-184. doi:10.1038/mp.2010.131. PubMed: 21242991.
    • (2012) Mol Psychiatry , vol.17 , pp. 173-184
    • Eriksson, T.M.1    Delagrange, P.2    Spedding, M.3    Popoli, M.4    Mathé, A.A.5
  • 110
    • 84867120199 scopus 로고    scopus 로고
    • Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders
    • doi: 10.1016/j.neuron.2012.09.013
    • Lesch KP, Waider J, (2012) Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders. Neuron 76: 175-191. doi:10.1016/j.neuron.2012.09.013. PubMed: 23040814.
    • (2012) Neuron , vol.76 , pp. 175-191
    • Lesch, K.P.1    Waider, J.2
  • 111
    • 33750506086 scopus 로고    scopus 로고
    • Arc/Arg3. 1 interacts with the endocytic machinery to regulate AMPA receptor trafficking
    • doi: 10.1016/j.neuron.2006.08.033
    • Chowdhury S, Shepherd JD, Okuno H, Lyford G, Petralia RS, et al. (2006) Arc/Arg3. 1 interacts with the endocytic machinery to regulate AMPA receptor trafficking. Neuron 52: 445-459. doi:10.1016/j.neuron.2006.08.033. PubMed: 17088211.
    • (2006) Neuron , vol.52 , pp. 445-459
    • Chowdhury, S.1    Shepherd, J.D.2    Okuno, H.3    Lyford, G.4    Petralia, R.S.5
  • 112
    • 0028232485 scopus 로고
    • Differential expression of fos family and jun family mRNAs in the rat hypothalamo-pituitary-adrenal axis after immobilization stress
    • doi: 10.1016/0169-328X(94)90141-4
    • Senba E, Umemoto S, Kawai Y, Noguchi K, (1994) Differential expression of fos family and jun family mRNAs in the rat hypothalamo-pituitary-adrenal axis after immobilization stress. Mol Brain Res 24: 283-294. doi:10.1016/0169-328X(94)90141-4. PubMed: 7968368.
    • (1994) Mol Brain Res , vol.24 , pp. 283-294
    • Senba, E.1    Umemoto, S.2    Kawai, Y.3    Noguchi, K.4
  • 113
    • 0030272981 scopus 로고    scopus 로고
    • Persistent c-fos expression in the brains of mice with chronic social stress
    • doi: 10.1016/S0168-0102(96)01088-7
    • Matsuda S, Peng H, Yoshimura H, Wen T-C, Fukuda T, et al. (1996) Persistent c-fos expression in the brains of mice with chronic social stress. Neurosci Res 26: 157-170. doi:10.1016/S0168-0102(96)01088-7. PubMed: 8953578.
    • (1996) Neurosci Res , vol.26 , pp. 157-170
    • Matsuda, S.1    Peng, H.2    Yoshimura, H.3    Wen, T.-C.4    Fukuda, T.5
  • 114
    • 0023937138 scopus 로고
    • Chronic Stress Increases Serotonin and Noradrenaline in Rat Brain and Sensitizes Their Responses to a Further Acute Stress
    • doi: 10.1111/j.1471-4159.1988.tb02462.x
    • Adell A, Garcia-Marquez C, Armario A, Gelpi E, (1988) Chronic Stress Increases Serotonin and Noradrenaline in Rat Brain and Sensitizes Their Responses to a Further Acute Stress. J Neurochem 50: 1678-1681. doi:10.1111/j.1471-4159.1988.tb02462.x. PubMed: 2453609.
    • (1988) J Neurochem , vol.50 , pp. 1678-1681
    • Adell, A.1    Garcia-Marquez, C.2    Armario, A.3    Gelpi, E.4
  • 115
    • 0026939448 scopus 로고
    • Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons
    • doi: 10.1002/hipo.450020410
    • Watanabe Y, Gould E, Cameron HA, Daniels DC, McEwen BS, (1992) Phenytoin prevents stress- and corticosterone-induced atrophy of CA3 pyramidal neurons. Hippocampus 2: 431-435. doi:10.1002/hipo.450020410. PubMed: 1308199.
    • (1992) Hippocampus , vol.2 , pp. 431-435
    • Watanabe, Y.1    Gould, E.2    Cameron, H.A.3    Daniels, D.C.4    McEwen, B.S.5
  • 116
    • 0026781307 scopus 로고
    • Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons
    • doi: 10.1016/0006-8993(92)91597-8
    • Watanabe Y, Gould E, McEwen BS, (1992) Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons. Brain Res 588: 341-345. doi:10.1016/0006-8993(92)91597-8. PubMed: 1393587.
    • (1992) Brain Res , vol.588 , pp. 341-345
    • Watanabe, Y.1    Gould, E.2    McEwen, B.S.3
  • 117
    • 0026493735 scopus 로고
    • Tianeptine attenuates stress-induced morphological changes in the hippocampus
    • doi: 10.1016/0014-2999(92)90830-W
    • Watanabe Y, Gould E, Daniels DC, Cameron H, McEwen BS, (1992) Tianeptine attenuates stress-induced morphological changes in the hippocampus. Eur J Pharmacol 222: 157-162. doi:10.1016/0014-2999(92)90830-W. PubMed: 1468492.
    • (1992) Eur J Pharmacol , vol.222 , pp. 157-162
    • Watanabe, Y.1    Gould, E.2    Daniels, D.C.3    Cameron, H.4    McEwen, B.S.5
  • 118
    • 0029146057 scopus 로고
    • Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: comparison of stressors
    • doi: 10.1016/0306-4522(95)00256-I
    • Magariños AM, McEwen BS, (1995) Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: comparison of stressors. Neuroscience 69: 83-88. doi:10.1016/0306-4522(95)00256-I. PubMed: 8637635.
    • (1995) Neuroscience , vol.69 , pp. 83-88
    • Magariños, A.M.1    McEwen, B.S.2
  • 119
    • 0029120661 scopus 로고
    • Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors
    • doi: 10.1016/0306-4522(95)00259-L
    • Magariños AM, McEwen BS, (1995) Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors. Neuroscience 69: 89-98. doi:10.1016/0306-4522(95)00259-L. PubMed: 8637636.
    • (1995) Neuroscience , vol.69 , pp. 89-98
    • Magariños, A.M.1    McEwen, B.S.2
  • 120
    • 0029144199 scopus 로고
    • Effect of chronic restraint stress on dendritic spines and excrescences of hippocampal CA3 pyramidal neurons--a quantitative study
    • doi: 10.1016/0006-8993(95)00822-8
    • Sunanda, Rao MS, Raju TR, (1995) Effect of chronic restraint stress on dendritic spines and excrescences of hippocampal CA3 pyramidal neurons--a quantitative study. Brain Res 694: 312-317. doi:10.1016/0006-8993(95)00822-8. PubMed: 8974660.
    • (1995) Brain Res , vol.694 , pp. 312-317
    • Sunanda, R.M.S.1    Raju, T.R.2
  • 121
    • 0028078663 scopus 로고
    • Repeated stress causes reversible impairments of spatial memory performance
    • doi: 10.1016/0006-8993(94)91778-7
    • Luine V, Villegas M, Martinez C, McEwen BS, (1994) Repeated stress causes reversible impairments of spatial memory performance. Brain Res 639: 167-170. doi:10.1016/0006-8993(94)91778-7. PubMed: 8180832.
    • (1994) Brain Res , vol.639 , pp. 167-170
    • Luine, V.1    Villegas, M.2    Martinez, C.3    McEwen, B.S.4
  • 122
    • 0030447110 scopus 로고    scopus 로고
    • Chronic stress impairs rat spatial memory on the Y maze, and this effect is blocked by tianeptine pretreatment
    • doi: 10.1037/0735-7044.110.6.1321
    • Conrad CD, Galea LA, Kuroda Y, McEwen BS, (1996) Chronic stress impairs rat spatial memory on the Y maze, and this effect is blocked by tianeptine pretreatment. Behav Neurosci 110: 1321-1334. doi:10.1037/0735-7044.110.6.1321. PubMed: 8986335.
    • (1996) Behav Neurosci , vol.110 , pp. 1321-1334
    • Conrad, C.D.1    Galea, L.A.2    Kuroda, Y.3    McEwen, B.S.4
  • 123
    • 0033980604 scopus 로고    scopus 로고
    • Serotonin may stimulate granule cell proliferation in the adult hippocampus, as observed in rats grafted with foetal raphe neurons
    • doi: 10.1046/j.1460-9568.2000.00932.x
    • Brezun JM, Daszuta A, (2000) Serotonin may stimulate granule cell proliferation in the adult hippocampus, as observed in rats grafted with foetal raphe neurons. Eur J Neurosci 12: 391-396. doi:10.1046/j.1460-9568.2000.00932.x. PubMed: 10651896.
    • (2000) Eur J Neurosci , vol.12 , pp. 391-396
    • Brezun, J.M.1    Daszuta, A.2
  • 124
    • 33744919791 scopus 로고    scopus 로고
    • Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis
    • doi: 10.1016/j.biopsych.2005.11.025
    • Banasr M, Soumier A, Hery M, Mocaër E, Daszuta A, (2006) Agomelatine, a new antidepressant, induces regional changes in hippocampal neurogenesis. Biol Psychiatry 59: 1087-1096. doi:10.1016/j.biopsych.2005.11.025. PubMed: 16499883.
    • (2006) Biol Psychiatry , vol.59 , pp. 1087-1096
    • Banasr, M.1    Soumier, A.2    Hery, M.3    Mocaër, E.4    Daszuta, A.5
  • 125
    • 76749112910 scopus 로고    scopus 로고
    • Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells
    • doi: 10.1038/npp.2009.181
    • Benninghoff J, Gritti A, Rizzi M, Lamorte G, Schloesser RJ, et al. (2010) Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells. Neuropsychopharmacol 35: 893-903. doi:10.1038/npp.2009.181. PubMed: 20010549.
    • (2010) Neuropsychopharmacol , vol.35 , pp. 893-903
    • Benninghoff, J.1    Gritti, A.2    Rizzi, M.3    Lamorte, G.4    Schloesser, R.J.5
  • 126
    • 79960700818 scopus 로고    scopus 로고
    • A mixed polyunsaturated fatty acid diet normalizes hippocampal neurogenesis and reduces anxiety in serotonin transporter knockout rats
    • doi: 10.1097/FBP.0b013e328347881b
    • Schipper P, Kiliaan AJ, Homberg JR, (2011) A mixed polyunsaturated fatty acid diet normalizes hippocampal neurogenesis and reduces anxiety in serotonin transporter knockout rats. Behav Pharmacol 22: 324-334. doi:10.1097/FBP.0b013e328347881b. PubMed: 21606840.
    • (2011) Behav Pharmacol , vol.22 , pp. 324-334
    • Schipper, P.1    Kiliaan, A.J.2    Homberg, J.R.3
  • 127
    • 33644857118 scopus 로고    scopus 로고
    • Paradoxical effects of learning the Morris water maze on adult hippocampal neurogenesis in mice may be explained by a combination of stress and physical activity
    • doi: 10.1111/j.1601-183X.2005.00129.x
    • Ehninger D, Kempermann G, (2006) Paradoxical effects of learning the Morris water maze on adult hippocampal neurogenesis in mice may be explained by a combination of stress and physical activity. Genes Brain Behav 5: 29-39. doi:10.1111/j.1601-183X.2005.00129.x. PubMed: 16436186.
    • (2006) Genes Brain Behav , vol.5 , pp. 29-39
    • Ehninger, D.1    Kempermann, G.2
  • 128
    • 71549167579 scopus 로고    scopus 로고
    • Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action
    • doi: 10.1016/j.euroneuro.2009.08.003
    • Lucassen PJ, Meerlo P, Naylor AS, van Dam AM, Dayer AG, et al. (2010) Regulation of adult neurogenesis by stress, sleep disruption, exercise and inflammation: Implications for depression and antidepressant action. Eur Neuropsychopharmacol 20: 1-17. doi:10.1016/j.euroneuro.2009.08.003. PubMed: 19748235.
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 1-17
    • Lucassen, P.J.1    Meerlo, P.2    Naylor, A.S.3    van Dam, A.M.4    Dayer, A.G.5
  • 129
    • 22244446492 scopus 로고    scopus 로고
    • Decreased proliferation in the adult rat hippocampus after exposure to the Morris water maze and its reversal by fluoxetine
    • doi: 10.1016/j.bbr.2005.04.013
    • Námestková K, Simonová Z, Syková E, (2005) Decreased proliferation in the adult rat hippocampus after exposure to the Morris water maze and its reversal by fluoxetine. Behav Brain Res 163: 26-32. doi:10.1016/j.bbr.2005.04.013. PubMed: 15941600.
    • (2005) Behav Brain Res , vol.163 , pp. 26-32
    • Námestková, K.1    Simonová, Z.2    Syková, E.3
  • 130
    • 78049467264 scopus 로고    scopus 로고
    • Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans
    • doi: 10.1093/brain/awq215
    • Coras R, Siebzehnrubl FA, Pauli E, Huttner HB, Njunting M, et al. (2010) Low proliferation and differentiation capacities of adult hippocampal stem cells correlate with memory dysfunction in humans. Brain 133: 3359-3372. doi:10.1093/brain/awq215. PubMed: 20719879.
    • (2010) Brain , vol.133 , pp. 3359-3372
    • Coras, R.1    Siebzehnrubl, F.A.2    Pauli, E.3    Huttner, H.B.4    Njunting, M.5
  • 131
    • 0032434817 scopus 로고    scopus 로고
    • Functional differentiation in the hippocampus
    • doi: 10.1002/(SICI)1098-1063(1998)8:6
    • Moser MB, Moser EI, (1998) Functional differentiation in the hippocampus. Hippocampus 8: 608-619. doi:10.1002/(SICI)1098-1063(1998)8:6. PubMed: 9882018<608::AID-HIPO3>3.0.CO;2-7.
    • (1998) Hippocampus , vol.8 , pp. 608-619
    • Moser, M.B.1    Moser, E.I.2
  • 132
    • 0028826942 scopus 로고
    • Learning-related changes in hippocampal field potentials
    • doi: 10.1016/0166-4328(95)00051-8
    • Moser EI, (1995) Learning-related changes in hippocampal field potentials. Behav Brain Res 71: 11-18. doi:10.1016/0166-4328(95)00051-8. PubMed: 8747171.
    • (1995) Behav Brain Res , vol.71 , pp. 11-18
    • Moser, E.I.1
  • 133
    • 0036333632 scopus 로고    scopus 로고
    • Hippocampal contributions to episodic encoding: insights from relational and item-based learning
    • doi: 10.1152/jn00046.2002
    • Davachi L, Wagner AD, (2002) Hippocampal contributions to episodic encoding: insights from relational and item-based learning. J Neurophysiol 88: 982-990. doi:10.1152/jn00046.2002. PubMed: 12163547.
    • (2002) J Neurophysiol , vol.88 , pp. 982-990
    • Davachi, L.1    Wagner, A.D.2
  • 134
    • 0025597946 scopus 로고
    • Hippocampal Pathway to the Amygdala and Stress-Ulcer Development
    • doi: 10.1016/0361-9230(90)90044-Z
    • Henke P, (1990) Hippocampal Pathway to the Amygdala and Stress-Ulcer Development. Brain. Res Bull 25: 691-695. doi:10.1016/0361-9230(90)90044-Z.
    • (1990) Brain. Res Bull , vol.25 , pp. 691-695
    • Henke, P.1
  • 135
    • 0032101122 scopus 로고    scopus 로고
    • Ventral subiculum regulates hypothalamo-pituitary-adrenocortical and behavioural responses to cognitive stressors
    • doi: 10.1016/S0306-4522(98)00055-4
    • Herman JP, Dolgas CM, Carlson SL, (1998) Ventral subiculum regulates hypothalamo-pituitary-adrenocortical and behavioural responses to cognitive stressors. Neuroscience 86: 449-459. doi:10.1016/S0306-4522(98)00055-4. PubMed: 9881860.
    • (1998) Neuroscience , vol.86 , pp. 449-459
    • Herman, J.P.1    Dolgas, C.M.2    Carlson, S.L.3
  • 136
    • 73549123839 scopus 로고    scopus 로고
    • Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?
    • doi: 10.1016/j.neuron.2009.11.031
    • Fanselow MS, Dong H-W, (2010) Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures? Neuron 65: 7-19. doi:10.1016/j.neuron.2009.11.031. PubMed: 20152109.
    • (2010) Neuron , vol.65 , pp. 7-19
    • Fanselow, M.S.1    Dong, H.-W.2
  • 137
    • 78649615738 scopus 로고    scopus 로고
    • Stress-induced dynamic routing of hippocampal connectivity: A hypothesis
    • doi: 10.1002/hipo.20751
    • Segal M, Richter-Levin G, Maggio N, (2010) Stress-induced dynamic routing of hippocampal connectivity: A hypothesis. Hippocampus 20: 1332-1338. doi:10.1002/hipo.20751. PubMed: 20082290.
    • (2010) Hippocampus , vol.20 , pp. 1332-1338
    • Segal, M.1    Richter-Levin, G.2    Maggio, N.3
  • 138
    • 0033577751 scopus 로고    scopus 로고
    • Projections of the median raphe nucleus in the rat
    • doi: 10.1002/(SICI)1096-9861(19990517)407:4<555::AID-CNE7>3.0.CO;2-E
    • Vertes RP, Fortin WJ, Crane AM, (1999) Projections of the median raphe nucleus in the rat. J Comp Neurol 407: 555-582. doi:10.1002/(SICI)1096-9861(19990517)407:4<555::AID-CNE7>3.0.CO;2-E. PubMed: 10235645.
    • (1999) J Comp Neurol , vol.407 , pp. 555-582
    • Vertes, R.P.1    Fortin, W.J.2    Crane, A.M.3
  • 139
    • 0034703446 scopus 로고    scopus 로고
    • Changes in hippocampal morphology following chronic treatment with the synthetic cannabinoid WIN 55
    • doi: 10.1016/S0006-8993(00)02739-6, Retrieved onpublished at whilst December year 1111 from
    • Lawston J, Borella A, Robinson JK, Whitaker-Azmitia PM, (2000) Changes in hippocampal morphology following chronic treatment with the synthetic cannabinoid WIN 55. Brain Res 877: 407-410. pp. 212-212. Retrieved onpublished at whilst December year 1111 from. doi:10.1016/S0006-8993(00)02739-6.
    • (2000) Brain Res , vol.877
    • Lawston, J.1    Borella, A.2    Robinson, J.K.3    Whitaker-Azmitia, P.M.4
  • 140
    • 1542324234 scopus 로고    scopus 로고
    • Regional differences in enhanced neurogenesis in the dentate gyrus of adult rats after transient forebrain ischemia
    • PubMed: 14651266
    • Choi Y-S, Lee M-Y, Sung K-W, Jeong S-W, Choi J-S, et al. (2003) Regional differences in enhanced neurogenesis in the dentate gyrus of adult rats after transient forebrain ischemia. Mol Cells 16: 232-238. PubMed: 14651266.
    • (2003) Mol Cells , vol.16 , pp. 232-238
    • Choi, Y.-S.1    Lee, M.-Y.2    Sung, K.-W.3    Jeong, S.-W.4    Choi, J.-S.5
  • 141
    • 34249780808 scopus 로고    scopus 로고
    • Asymmetry in enhanced neurogenesis in the rostral dentate gyrus following kainic acid-induced status epilepticus in adult rats
    • doi: 10.1007/BF02977661
    • Choi Y-S, Cho K-O, Kim SY, (2007) Asymmetry in enhanced neurogenesis in the rostral dentate gyrus following kainic acid-induced status epilepticus in adult rats. Arch Pharm Res 30: 646-652. doi:10.1007/BF02977661. PubMed: 17615686.
    • (2007) Arch Pharm Res , vol.30 , pp. 646-652
    • Choi, Y.-S.1    Cho, K.-O.2    Kim, S.Y.3
  • 142
    • 23844464066 scopus 로고    scopus 로고
    • Sparse, environmentally selective expression of Arc RNA in the upper blade of the rodent fascia dentata by brief spatial experience
    • doi: 10.1002/hipo.20091
    • Chawla MK, Guzowski JF, Ramirez-Amaya V, Lipa P, Hoffman KL, et al. (2005) Sparse, environmentally selective expression of Arc RNA in the upper blade of the rodent fascia dentata by brief spatial experience. Hippocampus 15: 579-586. doi:10.1002/hipo.20091. PubMed: 15920719.
    • (2005) Hippocampus , vol.15 , pp. 579-586
    • Chawla, M.K.1    Guzowski, J.F.2    Ramirez-Amaya, V.3    Lipa, P.4    Hoffman, K.L.5
  • 143
    • 77449092328 scopus 로고    scopus 로고
    • Structural Plasticity and Hippocampal Function
    • doi: 10.1146/annurev.psych.093008.100359
    • Leuner B, Gould E, (2010) Structural Plasticity and Hippocampal Function. Annu Rev Psychol 61: 111-140. doi:10.1146/annurev.psych.093008.100359. PubMed: 19575621.
    • (2010) Annu Rev Psychol , vol.61 , pp. 111-140
    • Leuner, B.1    Gould, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.