메뉴 건너뛰기




Volumn 34, Issue 3, 2009, Pages 317-331

Impaired hypothalamic-pituitary-adrenal axis and its feedback regulation in serotonin transporter knockout mice

Author keywords

CRF mRNA; CRF type 1 receptors; Dexamethasone; Glucocorticoid receptors; Hypothalamus; Pituitary; Stress

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; SEROTONIN TRANSPORTER;

EID: 59249089847     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2008.09.011     Document Type: Article
Times cited : (47)

References (53)
  • 1
    • 0030902768 scopus 로고    scopus 로고
    • Differential regulation of hypothalamic pituitary corticotropin releasing hormone receptors during development of adjuvant-induced arthritis in the rat
    • Aguilera G., Jessop D.S., Harbuz M.S., Kiss A., and Lightman S.L. Differential regulation of hypothalamic pituitary corticotropin releasing hormone receptors during development of adjuvant-induced arthritis in the rat. J. Endocrinol. 153 (1997) 185-191
    • (1997) J. Endocrinol. , vol.153 , pp. 185-191
    • Aguilera, G.1    Jessop, D.S.2    Harbuz, M.S.3    Kiss, A.4    Lightman, S.L.5
  • 2
    • 0035038462 scopus 로고    scopus 로고
    • Regulation of pituitary corticotropin releasing hormone receptors
    • Aguilera G., Rabadan-Diehl C., and Nikodemova M. Regulation of pituitary corticotropin releasing hormone receptors. Peptides 22 (2001) 769-774
    • (2001) Peptides , vol.22 , pp. 769-774
    • Aguilera, G.1    Rabadan-Diehl, C.2    Nikodemova, M.3
  • 3
    • 45149113856 scopus 로고    scopus 로고
    • Pituitary-adrenal and sympathetic nervous system responses to stress in women remitted from recurrent major depression
    • Ahrens T., Deuschle M., Krumm B., Van Der P.G., den Boer J.A., and Lederbogen F. Pituitary-adrenal and sympathetic nervous system responses to stress in women remitted from recurrent major depression. Psychosom. Med. (2008)
    • (2008) Psychosom. Med.
    • Ahrens, T.1    Deuschle, M.2    Krumm, B.3    Van Der, P.G.4    den Boer, J.A.5    Lederbogen, F.6
  • 4
    • 0031978809 scopus 로고    scopus 로고
    • Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymethamphetamine ("ecstasy") in serotonin transporter-deficient mice
    • Bengel D., Murphy D.L., Andrews A.M., Wichems C.H., Feltner D., Heils A., et al. Altered brain serotonin homeostasis and locomotor insensitivity to 3,4-methylenedioxymethamphetamine ("ecstasy") in serotonin transporter-deficient mice. Mol. Pharmacol. 53 (1998) 649-655
    • (1998) Mol. Pharmacol. , vol.53 , pp. 649-655
    • Bengel, D.1    Murphy, D.L.2    Andrews, A.M.3    Wichems, C.H.4    Feltner, D.5    Heils, A.6
  • 6
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
    • Caspi A., Sugden K., Moffitt T.E., Taylor A., Craig I.W., Harrington H., et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 301 (2003) 386-389
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3    Taylor, A.4    Craig, I.W.5    Harrington, H.6
  • 7
    • 0035783476 scopus 로고    scopus 로고
    • Stressor categorization: acute physical and psychological stressors elicit distinctive recruitment patterns in the amygdala and in medullary noradrenergic cell groups
    • Dayas C.V., Buller K.M., Crane J.W., Xu Y., and Day T.A. Stressor categorization: acute physical and psychological stressors elicit distinctive recruitment patterns in the amygdala and in medullary noradrenergic cell groups. Eur. J. Neurosci. 14 (2001) 1143-1152
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 1143-1152
    • Dayas, C.V.1    Buller, K.M.2    Crane, J.W.3    Xu, Y.4    Day, T.A.5
  • 8
    • 0032525279 scopus 로고    scopus 로고
    • Reduced activity of hypothalamic corticotropin-releasing hormone neurons in transgenic mice with impaired glucocorticoid receptor function
    • Dijkstra I., Tilders F.J.H., Aguilera G., Kiss A., Rabadan-Diehl C., Barden N., et al. Reduced activity of hypothalamic corticotropin-releasing hormone neurons in transgenic mice with impaired glucocorticoid receptor function. J. Neurosci. 18 (1998) 3909-3918
    • (1998) J. Neurosci. , vol.18 , pp. 3909-3918
    • Dijkstra, I.1    Tilders, F.J.H.2    Aguilera, G.3    Kiss, A.4    Rabadan-Diehl, C.5    Barden, N.6
  • 9
    • 42549106569 scopus 로고    scopus 로고
    • Salivary cortisol levels in children of low-income women with high depressive symptomatology
    • Fernald L.C., Burke H.M., and Gunnar M.R. Salivary cortisol levels in children of low-income women with high depressive symptomatology. Dev. Psychopathol. 20 (2008) 423-436
    • (2008) Dev. Psychopathol. , vol.20 , pp. 423-436
    • Fernald, L.C.1    Burke, H.M.2    Gunnar, M.R.3
  • 10
    • 0033525170 scopus 로고    scopus 로고
    • Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets
    • Greenberg B.D., Tolliver T.J., Huang S.J., Li Q., Bengel D., and Murphy D.L. Genetic variation in the serotonin transporter promoter region affects serotonin uptake in human blood platelets. Am. J. Med. Genet. 88 (1999) 83-87
    • (1999) Am. J. Med. Genet. , vol.88 , pp. 83-87
    • Greenberg, B.D.1    Tolliver, T.J.2    Huang, S.J.3    Li, Q.4    Bengel, D.5    Murphy, D.L.6
  • 11
    • 0042844776 scopus 로고    scopus 로고
    • Galanin GAL-R1 receptor null mutant mice display increased anxiety-like behavior specific to the elevated plus-maze
    • Holmes A., Kinney J.W., Wrenn C.C., Li Q., Yang R.J., Ma L., et al. Galanin GAL-R1 receptor null mutant mice display increased anxiety-like behavior specific to the elevated plus-maze. Neuropsychopharmacology 28 (2003) 1031-1044
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1031-1044
    • Holmes, A.1    Kinney, J.W.2    Wrenn, C.C.3    Li, Q.4    Yang, R.J.5    Ma, L.6
  • 12
    • 0345305849 scopus 로고    scopus 로고
    • Abnormal anxiety-related behaviour in serotonin transporter null mutant mice: the influence of genetic background
    • Holmes A., Li Q., Murphy D.L., Gold E., and Crawley J.N. Abnormal anxiety-related behaviour in serotonin transporter null mutant mice: the influence of genetic background. Genes Brain Behav. 2 (2003) 365-380
    • (2003) Genes Brain Behav. , vol.2 , pp. 365-380
    • Holmes, A.1    Li, Q.2    Murphy, D.L.3    Gold, E.4    Crawley, J.N.5
  • 13
    • 0242391960 scopus 로고    scopus 로고
    • Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression
    • Holmes A., Murphy D.L., and Crawley J.N. Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biol. Psychiatry 54 (2003) 953-959
    • (2003) Biol. Psychiatry , vol.54 , pp. 953-959
    • Holmes, A.1    Murphy, D.L.2    Crawley, J.N.3
  • 15
    • 0242600079 scopus 로고    scopus 로고
    • Mice lacking the serotonin transporter exhibit 5-HT1A receptor-mediated abnormalities in tests for anxiety-like behavior
    • Holmes A., Yang R.J., Lesch K.P., Crawley J.N., and Murphy D.L. Mice lacking the serotonin transporter exhibit 5-HT1A receptor-mediated abnormalities in tests for anxiety-like behavior. Neuropsychopharmacology 28 (2003) 2077-2088
    • (2003) Neuropsychopharmacology , vol.28 , pp. 2077-2088
    • Holmes, A.1    Yang, R.J.2    Lesch, K.P.3    Crawley, J.N.4    Murphy, D.L.5
  • 16
    • 12344328265 scopus 로고    scopus 로고
    • An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk
    • Hu X., Oroszi G., Chun J., Smith T.L., Goldman D., and Schuckit M.A. An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk. Alcohol Clin. Exp. Res. 29 (2005) 8-16
    • (2005) Alcohol Clin. Exp. Res. , vol.29 , pp. 8-16
    • Hu, X.1    Oroszi, G.2    Chun, J.3    Smith, T.L.4    Goldman, D.5    Schuckit, M.A.6
  • 17
    • 33646072813 scopus 로고    scopus 로고
    • Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
    • Hu X.Z., Lipsky R.H., Zhu G., Akhtar L.A., Taubman J., Greenberg B.D., et al. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am. J. Hum. Genet. 78 (2006) 815-826
    • (2006) Am. J. Hum. Genet. , vol.78 , pp. 815-826
    • Hu, X.Z.1    Lipsky, R.H.2    Zhu, G.3    Akhtar, L.A.4    Taubman, J.5    Greenberg, B.D.6
  • 18
    • 34247542195 scopus 로고    scopus 로고
    • Convergent genetic modulation of the endocrine stress response involves polymorphic variations of 5-HTT, COMT and MAOA
    • Jabbi M., Korf J., Kema I.P., Hartman C., Van Der P.G., Minderaa R.B., et al. Convergent genetic modulation of the endocrine stress response involves polymorphic variations of 5-HTT, COMT and MAOA. Mol. Psychiatry 12 (2007) 483-490
    • (2007) Mol. Psychiatry , vol.12 , pp. 483-490
    • Jabbi, M.1    Korf, J.2    Kema, I.P.3    Hartman, C.4    Van Der, P.G.5    Minderaa, R.B.6
  • 19
    • 33847107065 scopus 로고    scopus 로고
    • The developing use of heterozygous mutant mouse models in brain monoamine transporter research
    • Kalueff A.V., Ren-Patterson R.F., and Murphy D.L. The developing use of heterozygous mutant mouse models in brain monoamine transporter research. Trends Pharmacol. Sci. 28 (2007) 122-127
    • (2007) Trends Pharmacol. Sci. , vol.28 , pp. 122-127
    • Kalueff, A.V.1    Ren-Patterson, R.F.2    Murphy, D.L.3
  • 20
    • 0343091962 scopus 로고    scopus 로고
    • Glucocorticoid negative feedback selectively targets vasopressin transcription in parvocellular neurosecretory neurons
    • Kovacs K.J., Foldes A., and Sawchenko P.E. Glucocorticoid negative feedback selectively targets vasopressin transcription in parvocellular neurosecretory neurons. J. Neurosci. 20 (2000) 3843-3852
    • (2000) J. Neurosci. , vol.20 , pp. 3843-3852
    • Kovacs, K.J.1    Foldes, A.2    Sawchenko, P.E.3
  • 21
    • 0030070524 scopus 로고    scopus 로고
    • Sequence of stress-induced alterations in indices of synaptic and transcriptional activation in parvocellular neurosecretory neurons
    • Kovacs K.J., and Sawchenko P.E. Sequence of stress-induced alterations in indices of synaptic and transcriptional activation in parvocellular neurosecretory neurons. J. Neurosci. 16 (1996) 262-273
    • (1996) J. Neurosci. , vol.16 , pp. 262-273
    • Kovacs, K.J.1    Sawchenko, P.E.2
  • 22
    • 0034302849 scopus 로고    scopus 로고
    • 5-HT-HPA interactions in two models of transgenic mice relevant to major depression
    • Lanfumey L., La Cour C.M., Froger N., and Hamon M. 5-HT-HPA interactions in two models of transgenic mice relevant to major depression. Neurochem. Res. 25 (2000) 1199-1206
    • (2000) Neurochem. Res. , vol.25 , pp. 1199-1206
    • Lanfumey, L.1    La Cour, C.M.2    Froger, N.3    Hamon, M.4
  • 23
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • Lesch K.P., Bengel D., Heils A., Sabol S.Z., Greenberg B.D., Petri S., et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 274 (1996) 1527-1531
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3    Sabol, S.Z.4    Greenberg, B.D.5    Petri, S.6
  • 24
    • 33749055310 scopus 로고    scopus 로고
    • Cellular and molecular alterations in mice with deficient and reduced serotonin transporters
    • Li Q. Cellular and molecular alterations in mice with deficient and reduced serotonin transporters. Mol. Neurobiol. 34 (2006) 51-66
    • (2006) Mol. Neurobiol. , vol.34 , pp. 51-66
    • Li, Q.1
  • 25
    • 10044274046 scopus 로고    scopus 로고
    • Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences
    • Li Q., Holmes A., Ma L., Van de Kar L.D., Garcia F., and Murphy D.L. Medial hypothalamic 5-hydroxytryptamine (5-HT)1A receptors regulate neuroendocrine responses to stress and exploratory locomotor activity: application of recombinant adenovirus containing 5-HT1A sequences. J. Neurosci. 24 (2004) 10868-10877
    • (2004) J. Neurosci. , vol.24 , pp. 10868-10877
    • Li, Q.1    Holmes, A.2    Ma, L.3    Van de Kar, L.D.4    Garcia, F.5    Murphy, D.L.6
  • 26
    • 0034331195 scopus 로고    scopus 로고
    • Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: Gender and brain region differences
    • Li Q., Wichems C., Heils A., Lesch K.P., and Murphy D.L. Reduction in the density and expression, but not G-protein coupling, of serotonin receptors (5-HT1A) in 5-HT transporter knock-out mice: Gender and brain region differences. J. Neurosci. 20 (2000) 7888-7895
    • (2000) J. Neurosci. , vol.20 , pp. 7888-7895
    • Li, Q.1    Wichems, C.2    Heils, A.3    Lesch, K.P.4    Murphy, D.L.5
  • 27
    • 0032706095 scopus 로고    scopus 로고
    • Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice
    • Li Q., Wichems C., Heils A., Van de Kar L.D., Lesch K.P., and Murphy D.L. Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice. J. Pharmacol. Exp. Ther. 291 (1999) 999-1007
    • (1999) J. Pharmacol. Exp. Ther. , vol.291 , pp. 999-1007
    • Li, Q.1    Wichems, C.2    Heils, A.3    Van de Kar, L.D.4    Lesch, K.P.5    Murphy, D.L.6
  • 28
    • 45549088136 scopus 로고    scopus 로고
    • The neuroendocrinology of stress: a never ending story
    • Lightman S.L. The neuroendocrinology of stress: a never ending story. J. Neuroendocrinol. 20 (2008) 880-884
    • (2008) J. Neuroendocrinol. , vol.20 , pp. 880-884
    • Lightman, S.L.1
  • 29
    • 0029085878 scopus 로고
    • Regulation of hypothalamic and pituitary corticotropin-releasing hormone receptor messenger ribonucleic acid by adrenalectomy and glucocorticoids
    • Luo X., Kiss A., Rabadan-Diehl C., and Aguilera G. Regulation of hypothalamic and pituitary corticotropin-releasing hormone receptor messenger ribonucleic acid by adrenalectomy and glucocorticoids. Endocrinology 136 (1995) 3877-3883
    • (1995) Endocrinology , vol.136 , pp. 3877-3883
    • Luo, X.1    Kiss, A.2    Rabadan-Diehl, C.3    Aguilera, G.4
  • 30
    • 2342629856 scopus 로고    scopus 로고
    • Serotonin transporter: gene, genetic disorders, and pharmacogenetics
    • Murphy D.L., Lerner A., Rudnick G., and Lesch K.P. Serotonin transporter: gene, genetic disorders, and pharmacogenetics. Mol. Interventions 4 (2004) 109-123
    • (2004) Mol. Interventions , vol.4 , pp. 109-123
    • Murphy, D.L.1    Lerner, A.2    Rudnick, G.3    Lesch, K.P.4
  • 31
    • 38649099407 scopus 로고    scopus 로고
    • Targeting the murine serotonin transporter: insights into human neurobiology
    • Murphy D.L., and Lesch K.P. Targeting the murine serotonin transporter: insights into human neurobiology. Nat. Rev. Neurosci. 9 (2008) 85-96
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 85-96
    • Murphy, D.L.1    Lesch, K.P.2
  • 32
    • 0033152508 scopus 로고    scopus 로고
    • Molecular manipulations as tools for enhancing our understanding of 5-HT neurotransmission
    • Murphy D.L., Wichems C., Li Q., and Heils A. Molecular manipulations as tools for enhancing our understanding of 5-HT neurotransmission. Trends Pharmacol. Sci. 20 (1999) 246-252
    • (1999) Trends Pharmacol. Sci. , vol.20 , pp. 246-252
    • Murphy, D.L.1    Wichems, C.2    Li, Q.3    Heils, A.4
  • 33
    • 0033974338 scopus 로고    scopus 로고
    • The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants
    • Nakamura M., Ueno S., Sano A., and Tanabe H. The human serotonin transporter gene linked polymorphism (5-HTTLPR) shows ten novel allelic variants. Mol. Psychiatry 5 (2000) 32-38
    • (2000) Mol. Psychiatry , vol.5 , pp. 32-38
    • Nakamura, M.1    Ueno, S.2    Sano, A.3    Tanabe, H.4
  • 34
    • 0036000181 scopus 로고    scopus 로고
    • Multiple sites of control of type-1 corticotropin releasing hormone receptor levels in the pituitary
    • Nikodemova M., Diehl C.R., and Aguilera G. Multiple sites of control of type-1 corticotropin releasing hormone receptor levels in the pituitary. Arch. Physiol. Biochem. 110 (2002) 123-128
    • (2002) Arch. Physiol. Biochem. , vol.110 , pp. 123-128
    • Nikodemova, M.1    Diehl, C.R.2    Aguilera, G.3
  • 35
    • 19444365671 scopus 로고    scopus 로고
    • Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor
    • Pace T.W., and Spencer R.L. Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor. Am. J. Physiol. Endocrinol. Metab. 288 (2005) E1082-E1088
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.288
    • Pace, T.W.1    Spencer, R.L.2
  • 39
    • 34547697564 scopus 로고    scopus 로고
    • Late-life depressive symptoms are associated with both hyperactivity and hypoactivity of the hypothalamo-pituitary-adrenal axis
    • Penninx B.W., Beekman A.T., Bandinelli S., Corsi A.M., Bremmer M., Hoogendijk W.J., et al. Late-life depressive symptoms are associated with both hyperactivity and hypoactivity of the hypothalamo-pituitary-adrenal axis. Am. J. Geriatr. Psychiatry 15 (2007) 522-529
    • (2007) Am. J. Geriatr. Psychiatry , vol.15 , pp. 522-529
    • Penninx, B.W.1    Beekman, A.T.2    Bandinelli, S.3    Corsi, A.M.4    Bremmer, M.5    Hoogendijk, W.J.6
  • 40
    • 0029813764 scopus 로고    scopus 로고
    • Regulation of messenger ribonucleic acid for corticotropin releasing hormone receptor in the pituitary during stress
    • Rabadan-Diehl C., Kiss A., Camacho C., and Aguilera G. Regulation of messenger ribonucleic acid for corticotropin releasing hormone receptor in the pituitary during stress. Endocrinology 137 (1996) 3808-3814
    • (1996) Endocrinology , vol.137 , pp. 3808-3814
    • Rabadan-Diehl, C.1    Kiss, A.2    Camacho, C.3    Aguilera, G.4
  • 41
    • 0030853144 scopus 로고    scopus 로고
    • Regulation of pituitary corticotropin releasing hormone (CRH) receptor mRNA and CRH binding during adrenalectomy: role of glucocorticoids and hypothalamic factors
    • Rabadan-Diehl C., Makara G., Kiss A., Zelena D., and Aguilera G. Regulation of pituitary corticotropin releasing hormone (CRH) receptor mRNA and CRH binding during adrenalectomy: role of glucocorticoids and hypothalamic factors. J. Neuroendocrinol. 9 (1997) 689-697
    • (1997) J. Neuroendocrinol. , vol.9 , pp. 689-697
    • Rabadan-Diehl, C.1    Makara, G.2    Kiss, A.3    Zelena, D.4    Aguilera, G.5
  • 44
    • 34547895121 scopus 로고    scopus 로고
    • Interaction between childhood trauma and serotonin transporter gene variation in suicide
    • Roy A., Hu X.Z., Janal M.N., and Goldman D. Interaction between childhood trauma and serotonin transporter gene variation in suicide. Neuropsychopharmacology 32 (2007) 2046-2052
    • (2007) Neuropsychopharmacology , vol.32 , pp. 2046-2052
    • Roy, A.1    Hu, X.Z.2    Janal, M.N.3    Goldman, D.4
  • 45
    • 0038400186 scopus 로고    scopus 로고
    • Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice
    • Schmidt M., Oitzl M.S., Muller M.B., Ohl F., Wurst W., Holsboer F., et al. Regulation of the developing hypothalamic-pituitary-adrenal axis in corticotropin releasing hormone receptor 1-deficient mice. Neuroscience 119 (2003) 589-595
    • (2003) Neuroscience , vol.119 , pp. 589-595
    • Schmidt, M.1    Oitzl, M.S.2    Muller, M.B.3    Ohl, F.4    Wurst, W.5    Holsboer, F.6
  • 46
    • 28844440383 scopus 로고    scopus 로고
    • Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat
    • Szyf M., Weaver I.C., Champagne F.A., Diorio J., and Meaney M.J. Maternal programming of steroid receptor expression and phenotype through DNA methylation in the rat. Front Neuroendocrinol. 26 (2005) 139-162
    • (2005) Front Neuroendocrinol. , vol.26 , pp. 139-162
    • Szyf, M.1    Weaver, I.C.2    Champagne, F.A.3    Diorio, J.4    Meaney, M.J.5
  • 47
    • 3242666038 scopus 로고    scopus 로고
    • Life-long serotonin reuptake deficiency results in complex alterations in adrenomedullary responses to stress
    • Tjurmina O.A., Armando I., Saavedra J.M., Li Q., and Murphy D.L. Life-long serotonin reuptake deficiency results in complex alterations in adrenomedullary responses to stress. Ann. N. Y. Acad. Sci. 1018 (2004) 99-104
    • (2004) Ann. N. Y. Acad. Sci. , vol.1018 , pp. 99-104
    • Tjurmina, O.A.1    Armando, I.2    Saavedra, J.M.3    Li, Q.4    Murphy, D.L.5
  • 48
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J., De P.K., Pattyn F., Poppe B., Van R.N., De P.A., et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 3 (2002) RESEARCH0034
    • (2002) Genome Biol. , vol.3
    • Vandesompele, J.1    De, P.K.2    Pattyn, F.3    Poppe, B.4    Van, R.N.5    De, P.A.6
  • 50
    • 28044436691 scopus 로고    scopus 로고
    • Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life
    • Weaver I.C., Champagne F.A., Brown S.E., Dymov S., Sharma S., Meaney M.J., et al. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J. Neurosci. 25 (2005) 11045-11054
    • (2005) J. Neurosci. , vol.25 , pp. 11045-11054
    • Weaver, I.C.1    Champagne, F.A.2    Brown, S.E.3    Dymov, S.4    Sharma, S.5    Meaney, M.J.6
  • 51
    • 33847093463 scopus 로고    scopus 로고
    • The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes
    • Weaver I.C., D'Alessio A.C., Brown S.E., Hellstrom I.C., Dymov S., Sharma S., et al. The transcription factor nerve growth factor-inducible protein a mediates epigenetic programming: altering epigenetic marks by immediate-early genes. J. Neurosci. 27 (2007) 1756-1768
    • (2007) J. Neurosci. , vol.27 , pp. 1756-1768
    • Weaver, I.C.1    D'Alessio, A.C.2    Brown, S.E.3    Hellstrom, I.C.4    Dymov, S.5    Sharma, S.6
  • 52
    • 0036932871 scopus 로고    scopus 로고
    • From maternal care to gene expression: DNA methylation and the maternal programming of stress responses
    • Weaver I.C., Szyf M., and Meaney M.J. From maternal care to gene expression: DNA methylation and the maternal programming of stress responses. Endocr. Res. 28 (2002) 699
    • (2002) Endocr. Res. , vol.28 , pp. 699
    • Weaver, I.C.1    Szyf, M.2    Meaney, M.J.3
  • 53
    • 85047697355 scopus 로고    scopus 로고
    • Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression
    • Zalsman G., Huang Y.Y., Oquendo M.A., Burke A.K., Hu X.Z., Brent D.A., et al. Association of a triallelic serotonin transporter gene promoter region (5-HTTLPR) polymorphism with stressful life events and severity of depression. Am. J. Psychiatry 163 (2006) 1588-1593
    • (2006) Am. J. Psychiatry , vol.163 , pp. 1588-1593
    • Zalsman, G.1    Huang, Y.Y.2    Oquendo, M.A.3    Burke, A.K.4    Hu, X.Z.5    Brent, D.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.