-
1
-
-
0023433855
-
Supercoiling of the DNA template during transcription
-
doi: 10.1073/pnas.84.20.7024
-
Liu LF, Wang JC, (1987) Supercoiling of the DNA template during transcription. Proc Natl Acad Sci U S A 84: 7024-7027. doi:10.1073/pnas.84.20.7024. PubMed: 2823250.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 7024-7027
-
-
Liu, L.F.1
Wang, J.C.2
-
2
-
-
33749034730
-
Topoisomerase I inhibitors: camptothecins and beyond
-
doi: 10.1038/nrc1977
-
Pommier Y, (2006) Topoisomerase I inhibitors: camptothecins and beyond. Nat Rev Cancer 6: 789-802. doi:10.1038/nrc1977. PubMed: 16990856.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 789-802
-
-
Pommier, Y.1
-
3
-
-
0023924786
-
Identification of mammalian topoisomerase I as an intracellular target of the anticancer drug camptothecin
-
PubMed: 2832051
-
Hsiang Y-H, Liu LF, (1988) Identification of mammalian topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 48: 1722-1726. PubMed: 2832051.
-
(1988)
Cancer Res
, vol.48
, pp. 1722-1726
-
-
Hsiang, Y.-H.1
Liu, L.F.2
-
4
-
-
84872547120
-
Drugging topoisomerases: lessons and challenges
-
doi: 10.1021/cb300648v
-
Pommier Y, (2013) Drugging topoisomerases: lessons and challenges. ACS Chem Biol 8: 82-95. doi:10.1021/cb300648v. PubMed: 23259582.
-
(2013)
ACS Chem Biol
, vol.8
, pp. 82-95
-
-
Pommier, Y.1
-
5
-
-
0024420685
-
Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
-
PubMed: 2548710
-
Hsiang Y-H, Lihou MG, Liu LF, (1989) Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res 49: 5077-5082. PubMed: 2548710.
-
(1989)
Cancer Res
, vol.49
, pp. 5077-5082
-
-
Hsiang, Y.-H.1
Lihou, M.G.2
Liu, L.F.3
-
6
-
-
0030658833
-
Processing of topoisomerase I cleavable complexes into DNA damage by transcription
-
doi: 10.1093/nar/25.21.4181
-
Wu JX, Liu LF, (1997) Processing of topoisomerase I cleavable complexes into DNA damage by transcription. Nucleic Acids Res 25: 4181-4186. doi:10.1093/nar/25.21.4181. PubMed: 9336444.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 4181-4186
-
-
Wu, J.X.1
Liu, L.F.2
-
7
-
-
68249083044
-
Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks
-
doi: 10.1038/embor.2009.97
-
Sordet O, Redon CE, Guirouilh-Barbat J, Smith S, Solier S, et al. (2009) Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks. EMBO Rep 10: 887-893. doi:10.1038/embor.2009.97. PubMed: 19557000.
-
(2009)
EMBO Rep
, vol.10
, pp. 887-893
-
-
Sordet, O.1
Redon, C.E.2
Guirouilh-Barbat, J.3
Smith, S.4
Solier, S.5
-
8
-
-
0029947168
-
The anti-cancer drug camptothecin inhibits elongation but stimulates initiation of RNA polymerase II transcription
-
doi: 10.1093/carcin/17.1.31
-
Ljungman M, Hanawalt PC, (1996) The anti-cancer drug camptothecin inhibits elongation but stimulates initiation of RNA polymerase II transcription. Carcinogenesis 17: 31-35. doi:10.1093/carcin/17.1.31. PubMed: 8565133.
-
(1996)
Carcinogenesis
, vol.17
, pp. 31-35
-
-
Ljungman, M.1
Hanawalt, P.C.2
-
9
-
-
0030854371
-
Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin
-
doi: 10.1074/jbc.272.39.24159
-
Desai SD, Liu LF, Vazquez-Abad D, D'Arpa P, (1997) Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin. J Biol Chem 272: 24159-24164. doi:10.1074/jbc.272.39.24159. PubMed: 9305865.
-
(1997)
J Biol Chem
, vol.272
, pp. 24159-24164
-
-
Desai, S.D.1
Liu, L.F.2
Vazquez-Abad, D.3
D'Arpa, P.4
-
10
-
-
0345061277
-
Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions
-
doi: 10.1016/S1568-7864(03)00116-2
-
Plo I, Liao ZY, Barceló JM, Kohlhagen G, Caldecott KW, et al. (2003) Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions. DNA Repair (Amst) 2: 1087-1100. doi:10.1016/S1568-7864(03)00116-2. PubMed: 13679147.
-
(2003)
DNA Repair (Amst)
, vol.2
, pp. 1087-1100
-
-
Plo, I.1
Liao, Z.Y.2
Barceló, J.M.3
Kohlhagen, G.4
Caldecott, K.W.5
-
11
-
-
77952058117
-
Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison
-
doi: 10.1074/jbc.M110.101808
-
Sakasai R, Teraoka H, Takagi M, Tibbetts RS, (2010) Transcription-dependent activation of ataxia telangiectasia mutated prevents DNA-dependent protein kinase-mediated cell death in response to topoisomerase I poison. J Biol Chem 285: 15201-15208. doi:10.1074/jbc.M110.101808. PubMed: 20304914.
-
(2010)
J Biol Chem
, vol.285
, pp. 15201-15208
-
-
Sakasai, R.1
Teraoka, H.2
Takagi, M.3
Tibbetts, R.S.4
-
12
-
-
0035921573
-
Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation
-
doi: 10.1038/sj.onc.1204734
-
Ljungman M, O'Hagan HM, Paulsen MT, (2001) Induction of ser15 and lys382 modifications of p53 by blockage of transcription elongation. Oncogene 20: 5964-5971. doi:10.1038/sj.onc.1204734. PubMed: 11593403.
-
(2001)
Oncogene
, vol.20
, pp. 5964-5971
-
-
Ljungman, M.1
O'Hagan, H.M.2
Paulsen, M.T.3
-
13
-
-
0033590624
-
Inhibition of RNA polymerase II as a trigger for the p53 response
-
doi: 10.1038/sj.onc.1202356
-
Ljungman M, Zhang FF, Chen F, Rainbow AJ, McKay BC, (1999) Inhibition of RNA polymerase II as a trigger for the p53 response. Oncogene 18: 583-592. doi:10.1038/sj.onc.1202356. PubMed: 9989808.
-
(1999)
Oncogene
, vol.18
, pp. 583-592
-
-
Ljungman, M.1
Zhang, F.F.2
Chen, F.3
Rainbow, A.J.4
McKay, B.C.5
-
14
-
-
4544259868
-
Transcription - guarding the genome by sensing DNA damage
-
doi: 10.1038/nrc1435
-
Ljungman M, Lane DP, (2004) Transcription- guarding the genome by sensing DNA damage. Nat Rev Cancer 4: 727-737. doi:10.1038/nrc1435. PubMed: 15343279.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 727-737
-
-
Ljungman, M.1
Lane, D.P.2
-
15
-
-
84874848115
-
Topoisomerase IIbeta deficiency enhances camptothecin-induced apoptosis
-
doi: 10.1074/jbc.M112.415471
-
Lin RK, Ho CW, Liu LF, Lyu YL, (2013) Topoisomerase IIbeta deficiency enhances camptothecin-induced apoptosis. J Biol Chem 288: 7182-7192. doi:10.1074/jbc.M112.415471. PubMed: 23344961.
-
(2013)
J Biol Chem
, vol.288
, pp. 7182-7192
-
-
Lin, R.K.1
Ho, C.W.2
Liu, L.F.3
Lyu, Y.L.4
-
16
-
-
84871221721
-
PARP and CSB modulate the processing of transcription-mediated DNA strand breaks
-
PubMed: 23229313
-
Sakai A, Sakasai R, Kakeji Y, Kitao H, Maehara Y, (2012) PARP and CSB modulate the processing of transcription-mediated DNA strand breaks. Genes Genet Syst 87: 265-272. PubMed: 23229313.
-
(2012)
Genes Genet Syst
, vol.87
, pp. 265-272
-
-
Sakai, A.1
Sakasai, R.2
Kakeji, Y.3
Kitao, H.4
Maehara, Y.5
-
17
-
-
78650640724
-
Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex
-
doi: 10.1111/j.1365-2443.2010.01467.x
-
Horibata K, Saijo M, Bay MN, Lan L, Kuraoka I, et al. (2011) Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex. Genes Cells 16: 101-114. doi:10.1111/j.1365-2443.2010.01467.x. PubMed: 21143350.
-
(2011)
Genes Cells
, vol.16
, pp. 101-114
-
-
Horibata, K.1
Saijo, M.2
Bay, M.N.3
Lan, L.4
Kuraoka, I.5
-
18
-
-
0027173884
-
Hypersensitivity of Cockayne's syndrome cells to camptothecin is associated with the generation of abnormally high levels of double strand breaks in nascent DNA
-
PubMed: 7683249
-
Squires S, Ryan AJ, Strutt HL, Johnson RT, (1993) Hypersensitivity of Cockayne's syndrome cells to camptothecin is associated with the generation of abnormally high levels of double strand breaks in nascent DNA. Cancer Res 53: 2012-2019. PubMed: 7683249.
-
(1993)
Cancer Res
, vol.53
, pp. 2012-2019
-
-
Squires, S.1
Ryan, A.J.2
Strutt, H.L.3
Johnson, R.T.4
-
19
-
-
84873426026
-
Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response
-
doi: 10.1073/pnas.1219192110
-
Paulsen MT, Veloso A, Prasad J, Bedi K, Ljungman EA, et al. (2013) Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response. Proc Natl Acad Sci U S A 110: 2240-2245. doi:10.1073/pnas.1219192110. PubMed: 23345452.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 2240-2245
-
-
Paulsen, M.T.1
Veloso, A.2
Prasad, J.3
Bedi, K.4
Ljungman, E.A.5
-
20
-
-
79952481593
-
Topoisomerases, chromatin and transcription termination
-
doi: 10.4161/trns.2.2.14411
-
Durand-Dubief M, Svensson JP, Persson J, Ekwall K, (2011) Topoisomerases, chromatin and transcription termination. Transcription 2: 66-70. doi:10.4161/trns.2.2.14411. PubMed: 21468231.
-
(2011)
Transcription
, vol.2
, pp. 66-70
-
-
Durand-Dubief, M.1
Svensson, J.P.2
Persson, J.3
Ekwall, K.4
-
21
-
-
57849123049
-
RNA exosome depletion reveals transcription upstream of active human promoters
-
doi: 10.1126/science.1164096
-
Preker P, Nielsen J, Kammler S, Lykke-Andersen S, Christensen MS, et al. (2008) RNA exosome depletion reveals transcription upstream of active human promoters. Science 322: 1851-1854. doi:10.1126/science.1164096. PubMed: 19056938.
-
(2008)
Science
, vol.322
, pp. 1851-1854
-
-
Preker, P.1
Nielsen, J.2
Kammler, S.3
Lykke-Andersen, S.4
Christensen, M.S.5
-
22
-
-
84876842759
-
Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells
-
doi: 10.1016/j.molcel.2013.02.015
-
Danko CG, Hah N, Luo X, Martins AL, Core L, et al. (2013) Signaling pathways differentially affect RNA polymerase II initiation, pausing, and elongation rate in cells. Mol Cell 50: 212-222. doi:10.1016/j.molcel.2013.02.015. PubMed: 23523369.
-
(2013)
Mol Cell
, vol.50
, pp. 212-222
-
-
Danko, C.G.1
Hah, N.2
Luo, X.3
Martins, A.L.4
Core, L.5
-
23
-
-
2342471907
-
Regulation of ultraviolet light-induced gene expression by gene size
-
doi: 10.1073/pnas.0308181101
-
McKay BC, Stubbert LJ, Fowler CC, Smith JM, Cardamore RA, et al. (2004) Regulation of ultraviolet light-induced gene expression by gene size. Proc Natl Acad Sci U S A 101: 6582-6586. doi:10.1073/pnas.0308181101. PubMed: 15087501.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 6582-6586
-
-
McKay, B.C.1
Stubbert, L.J.2
Fowler, C.C.3
Smith, J.M.4
Cardamore, R.A.5
-
24
-
-
0000536643
-
DNA topoisomerase-targeting antitumor drugs can be studied in yeast
-
doi: 10.1073/pnas.85.20.7501
-
Nitiss J, Wang JC, (1988) DNA topoisomerase-targeting antitumor drugs can be studied in yeast. Proc Natl Acad Sci U S A 85: 7501-7505. doi:10.1073/pnas.85.20.7501. PubMed: 2845409.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 7501-7505
-
-
Nitiss, J.1
Wang, J.C.2
-
25
-
-
0033212103
-
DNA topoisomerase I-targeting drugs as radiation sensitizers
-
PubMed: 10550825
-
Chen AY, Choy H, Rothenberg ML, (1999) DNA topoisomerase I-targeting drugs as radiation sensitizers. Oncology 13: 39-46. PubMed: 10550825.
-
(1999)
Oncology
, vol.13
, pp. 39-46
-
-
Chen, A.Y.1
Choy, H.2
Rothenberg, M.L.3
-
26
-
-
0035137364
-
Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro
-
doi: 10.1054/bjoc.2000.1555
-
Bowman KJ, Newell DR, Calvert AH, Curtin NJ, (2001) Differential effects of the poly (ADP-ribose) polymerase (PARP) inhibitor NU1025 on topoisomerase I and II inhibitor cytotoxicity in L1210 cells in vitro. Br J Cancer 84: 106-112. doi:10.1054/bjoc.2000.1555. PubMed: 11139322.
-
(2001)
Br J Cancer
, vol.84
, pp. 106-112
-
-
Bowman, K.J.1
Newell, D.R.2
Calvert, A.H.3
Curtin, N.J.4
-
27
-
-
79956053314
-
Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells
-
doi: 10.1093/nar/gkq1304
-
Zhang YW, Regairaz M, Seiler JA, Agama KK, Doroshow JH, et al. (2011) Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells. Nucleic Acids Res 39: 3607-3620. doi:10.1093/nar/gkq1304. PubMed: 21227924.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 3607-3620
-
-
Zhang, Y.W.1
Regairaz, M.2
Seiler, J.A.3
Agama, K.K.4
Doroshow, J.H.5
-
28
-
-
84881452051
-
Transcription Poisoning by Topoisomerase I Is Controlled by Gene Length, Splice Sites, and miR-142-3p
-
doi: 10.1158/0008-5472.CAN-12-3504
-
Solier S, Ryan MC, Martin SE, Varma S, Kohn KW, et al. (2013) Transcription Poisoning by Topoisomerase I Is Controlled by Gene Length, Splice Sites, and miR-142-3p. Cancer Res 73: 4830-4839. doi:10.1158/0008-5472.CAN-12-3504. PubMed: 23786772.
-
(2013)
Cancer Res
, vol.73
, pp. 4830-4839
-
-
Solier, S.1
Ryan, M.C.2
Martin, S.E.3
Varma, S.4
Kohn, K.W.5
|