Delineation of the GPRC6A receptor signaling pathways using a mammalian cell line stably expressing the receptor

Journal of Pharmacology and Experimental Therapeutics

Volumn 347, Issue 2, 2013, Pages 298-309

  Jacobsen, Stine Engesgaard ^a   Nørskov Lauritsen, Lenea ^a   Thomsen, Alex Rojas Bie ^a,d   Smajilovic, Sanela ^a   Wellendorph, Petrine ^a   Larsson, Niklas H P ^b   Lehmann, Anders ^b   Bhatia, Vikram Kjøller ^a,c   Bräuner Osborne, Hans ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b ASTRAZENECA R AND D   (Sweden)

^c NOVOZYMES A S   (Denmark)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [6 [((17B) 3 METHOXYESTRA 1,3,5[10]TRIEN 17 YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 [N METHYL(2' MORPHOLINO 2' OXOETHYL)AMINO] 1(2'' PHENYL 1H INDOL 3'' YL)ETHANONE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ALPHA AMINO ACID; CALCIUM ION; CELL PROTEIN; CELL RECEPTOR; G PROTEIN COUPLED RECEPTOR FAMILY C GROUP 6 MEMBER A RECEPTOR; GQ PROTEIN INHIBITOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; ORNITHINE; OSTEOCALCIN; PROTEIN GQ; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; FEMALE; FLUORESCENCE; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; WESTERN BLOTTING;

ANIMALS; CHO CELLS; CRICETULUS; HEK293 CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; LIGANDS; MICE; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84886028401     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.206276     Document Type: Article

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