메뉴 건너뛰기




Volumn 73, Issue 20, 2013, Pages 6289-6298

Integrative radiogenomic profiling of squamous cell lung Cancer

(15)  Abazeed, Mohamed E a   Adams, Drew J f,h   Hurov, Kristen E i   Tamayo, Pablo h   Creighton, Chad J k   Sonkin, Dmitriy i   Giacomelli, Andrew O b   Du, Charles b   Fries, Daniel F d   Wong, Kwok Kin d   Mesirov, Jill P h   Loeffler, Jay S c   Schreiber, Stuart L b,f,g,h,j   Hammerman, Peter S d,h   Meyerson, Matthew d,e,h  


Author keywords

[No Author keywords available]

Indexed keywords

BUPARLISIB; KELCH LIKE ECH ASSOCIATED PROTEIN 1; MESSENGER RNA; TRANSCRIPTION FACTOR NRF2;

EID: 84886022329     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1616     Document Type: Article
Times cited : (103)

References (50)
  • 1
    • 0036911505 scopus 로고    scopus 로고
    • New chemotherapeutic agents: Update of major chemoradiation trials in solid tumors
    • Curran WJ. New chemotherapeutic agents: update of major chemoradiation trials in solid tumors. Oncology 2002; 63(SUPPL. 2): 29-38.
    • (2002) Oncology , vol.63 , Issue.SUPPL. 2 , pp. 29-38
    • Curran, W.J.1
  • 2
    • 73349096261 scopus 로고    scopus 로고
    • Resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
    • Hammerman PS, Janne PA, Johnson BE Resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. Clin Cancer Res 2009; 15:7502-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 7502-7509
    • Hammerman, P.S.1    Janne, P.A.2    Johnson, B.E.3
  • 3
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee J.C., Tracy S., Greulich H, Gabriel S, et al EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304:1497-500.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3    Tracy, S.4    Greulich, H.5    Gabriel, S.6
  • 5
    • 39049106219 scopus 로고    scopus 로고
    • Integrating global gene expression and radiation survival parameters across the 60 cell lines of the national cancer institute anticancer drug screen
    • Amundson SA, Do KT, Vinikoor L.C., Lee RA, Koch-Paiz CA, Ahn J, et al Integrating global gene expression and radiation survival parameters across the 60 cell lines of the National Cancer Institute Anticancer Drug Screen. Cancer Res 2008; 68:415-24.
    • (2008) Cancer Res , vol.68 , pp. 415-424
    • Amundson, S.A.1    Do, K.T.2    Vinikoor, L.C.3    Lee, R.A.4    Koch-Paiz, C.A.5    Ahn, J.6
  • 6
    • 69549122386 scopus 로고    scopus 로고
    • Systems biology modeling of the radiation sensitivity network: A biomarker discovery platform
    • Eschrich S, Zhang H, Zhao H., Boulware D, Lee JH, Bloom G, et al Systems biology modeling of the radiation sensitivity network: a biomarker discovery platform. Int J Radiat Oncol Biol Phys 2009; 75: 497-505.
    • (2009) Int J Radiat Oncol Biol Phys , vol.75 , pp. 497-505
    • Eschrich, S.1    Zhang, H.2    Zhao, H.3    Boulware, D.4    Lee, J.H.5    Bloom, G.6
  • 8
    • 84960962997 scopus 로고
    • Action of x-rays on Mammalian cells
    • Puck TT, Marcus PI Action of x-rays on mammalian cells. J Exp Med 1956; 103:653-66.
    • (1956) J Exp Med , vol.103 , pp. 653-666
    • Puck, T.T.1    Marcus, P.I.2
  • 9
    • 77954641944 scopus 로고    scopus 로고
    • Radiation-induced cell death mechanisms
    • Eriksson D, Stigbrand T. Radiation-induced cell death mechanisms. Tumour Biol 2010; 31:363-72.
    • (2010) Tumour Biol , vol.31 , pp. 363-372
    • Eriksson, D.1    Stigbrand, T.2
  • 10
    • 84863829078 scopus 로고    scopus 로고
    • Development of a high-content high-throughput screening assay for the discovery of ATM signaling inhibitors
    • Bardelle C, Boros J. Development of a high-content high-throughput screening assay for the discovery of ATM signaling inhibitors. J Biomol Screen 2012; 17:912-20.
    • (2012) J Biomol Screen , vol.17 , pp. 912-920
    • Bardelle, C.1    Boros, J.2
  • 13
    • 77952298828 scopus 로고    scopus 로고
    • Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer
    • Auperin A, Le Pechoux C, Rolland E, Curran W.J., Furuse K., Fournel P, et al Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer. J Clin Oncol 2010; 28:2181-90.
    • (2010) J Clin Oncol , vol.28 , pp. 2181-2190
    • Auperin, A.1    Le Pechoux, C.2    Rolland, E.3    Curran, W.J.4    Furuse, K.5    Fournel, P.6
  • 14
    • 84859169877 scopus 로고    scopus 로고
    • The cancer cell line encyclopedia enables predictive modelling of anticancer drug sensitivity
    • Barretina J, Caponigro G, Stransky N., Venkatesan K, Margolin AA, Kim S, et al The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 2012; 483:603-7.
    • (2012) Nature , vol.483 , pp. 603-607
    • Barretina, J.1    Caponigro, G.2    Stransky, N.3    Venkatesan, K.4    Margolin, A.A.5    Kim, S.6
  • 16
    • 80455178765 scopus 로고    scopus 로고
    • Optimized digital counting colonies of clonogenic assays using image J software and customized macros: Comparison with manualcounting
    • Cai Z, Chattopadhyay N, Liu W.J., Chan C., Pignol JP, Reilly RM Optimized digital counting colonies of clonogenic assays using Image J software and customized macros: comparison with manualcounting. Int J Radiat Biol 2011; 87:1135-46.
    • (2011) Int J Radiat Biol , vol.87 , pp. 1135-1146
    • Cai, Z.1    Chattopadhyay, N.2    Liu, W.J.3    Chan, C.4    Pignol, J.P.5    Reilly, R.M.6
  • 17
    • 79956121323 scopus 로고    scopus 로고
    • Nrf2 regulates hyperoxia-induced nox4 expression in human lung endothelium: Identification of functional antioxidant response elements on the nox4 promoter
    • Pendyala S, Moitra J, Kalari S., Kleeberger SR, Zhao Y, Reddy SP, et al Nrf2 regulates hyperoxia-induced Nox4 expression in human lung endothelium: identification of functional antioxidant response elements on the Nox4 promoter. Free Radic Biol Med 2011; 50: 1749-59.
    • (2011) Free Radic Biol Med , vol.50 , pp. 1749-1759
    • Pendyala, S.1    Moitra, J.2    Kalari, S.3    Kleeberger, S.R.4    Zhao, Y.5    Reddy, S.P.6
  • 18
    • 34248393855 scopus 로고    scopus 로고
    • HPV16 E6-mediated stabilization of ErbB2 in neoplastic transformation of human cervical keratinocytes
    • Narisawa-Saito M., Handa K, Yugawa T., Ohno S, Fujita M, Kiyono T. HPV16 E6-mediated stabilization of ErbB2 in neoplastic transformation of human cervical keratinocytes. Oncogene 2007; 26:2988-96.
    • (2007) Oncogene , vol.26 , pp. 2988-2996
    • Narisawa-Saito, M.1    Handa, K.2    Yugawa, T.3    Ohno, S.4    Fujita, M.5    Kiyono, T.6
  • 19
    • 0033102622 scopus 로고    scopus 로고
    • Activation of antioxidant/electrophile responsive elements in IMR-32 human neuroblastoma cells
    • Moehlenkamp JD, Johnson JA Activation of antioxidant/electrophile responsive elements in IMR-32 human neuroblastoma cells. Arch Biochem Biophys 1999; 363:98-106.
    • (1999) Arch Biochem Biophys , vol.363 , pp. 98-106
    • Moehlenkamp, J.D.1    Johnson, J.A.2
  • 22
    • 0023638936 scopus 로고
    • A panel of human lung carcinoma lines: Establishment, properties, and common characteristics
    • Duchesne GM, Eady JJ, Peacock J.H., Pera MF A panel of human lung carcinoma lines: establishment, properties, and common characteristics. Br J Cancer 1987; 56:287-93.
    • (1987) Br J Cancer , vol.56 , pp. 287-293
    • Duchesne, G.M.1    Eady, J.J.2    Peacock, J.H.3    Pera, M.F.4
  • 23
    • 0031577292 scopus 로고    scopus 로고
    • An nrf2/ small maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
    • Itoh K, Chiba T, Takahashi S., Ishii T, Igarashi K, Katoh Y., et al An Nrf2/ small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements. Biochem Biophys Res Commun 1997; 236:313-22.
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 313-322
    • Itoh, K.1    Chiba, T.2    Takahashi, S.3    Ishii, T.4    Igarashi, K.5    Katoh, Y.6
  • 24
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by nrf2 through binding to the amino-terminal neh2 domain
    • Itoh K, Wakabayashi N, Katoh Y., Ishii T, Igarashi K, Engel J.D., et al Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999; 13:76-86.
    • (1999) Genes Dev , vol.13 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3    Ishii, T.4    Igarashi, K.5    Engel, J.D.6
  • 25
    • 0034213842 scopus 로고    scopus 로고
    • Nrf2 and c-jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene
    • Jeyapaul J, Jaiswal AK Nrf2 and c-Jun regulation of antioxidant response element (ARE)-mediated expression and induction of gamma-glutamylcysteine synthetase heavy subunit gene. Biochem Pharmacol 2000; 59:1433-9.
    • (2000) Biochem Pharmacol , vol.59 , pp. 1433-1439
    • Jeyapaul, J.1    Jaiswal, A.K.2
  • 26
    • 0020027542 scopus 로고
    • The reaction of the hydroxyl radical with glutathione in neutral and alkaline aqueous solution
    • Sjoberg L, Eriksen TE, Revesz L. The reaction of the hydroxyl radical with glutathione in neutral and alkaline aqueous solution. Radiat Res 1982; 89:255-63.
    • (1982) Radiat Res , vol.89 , pp. 255-263
    • Sjoberg, L.1    Eriksen, T.E.2    Revesz, L.3
  • 27
    • 77958129306 scopus 로고    scopus 로고
    • Gain of nrf2 function in non-small-cell lung cancer cells confers radioresistance
    • Singh A, Bodas M, Wakabayashi N., Bunz F, Biswal S. Gain of Nrf2 function in non-small-cell lung cancer cells confers radioresistance. Antioxid Redox Signal 2010; 13:1627-37.
    • (2010) Antioxid Redox Signal , vol.13 , pp. 1627-1637
    • Singh, A.1    Bodas, M.2    Wakabayashi, N.3    Bunz, F.4    Biswal, S.5
  • 29
    • 51649130168 scopus 로고    scopus 로고
    • Cancer related mutations in NRF2 impair its recognition by keap1cul3 E3 ligase and promote Malignancy
    • Shibata T, Ohta T, Tong K.I., Kokubu A., Odogawa R, Tsuta K, et al Cancer related mutations in NRF2 impair its recognition by Keap1Cul3 E3 ligase and promote malignancy. Proc Natl Acad Sci U S A 2008; 105:13568-73.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 13568-13573
    • Shibata, T.1    Ohta, T.2    Tong, K.I.3    Kokubu, A.4    Odogawa, R.5    Tsuta, K.6
  • 30
    • 0035212419 scopus 로고    scopus 로고
    • Induction of xenobiotic enzymes bythe MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE)
    • Kong AN, Owuor E, Yu R., Hebbar V, Chen C, Hu R., et al Induction of xenobiotic enzymes bythe MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE). Drug Metab Rev 2001; 33: 255-71.
    • (2001) Drug Metab Rev , vol.33 , pp. 255-271
    • Kong, A.N.1    Owuor, E.2    Yu, R.3    Hebbar, V.4    Chen, C.5    Hu, R.6
  • 31
    • 33845876254 scopus 로고    scopus 로고
    • The connectivity map: A new tool for biomedical research
    • Lamb J. The Connectivity Map: a new tool for biomedical research. Nat Rev Cancer 2007; 7:54-60.
    • (2007) Nat Rev Cancer , vol.7 , pp. 54-60
    • Lamb, J.1
  • 32
    • 33749335282 scopus 로고    scopus 로고
    • The connectivity map: Using gene-expression signatures to connect small molecules, genes, and disease
    • Lamb J, Crawford ED, Peck D, Modell J.W., Blat IC, Wrobel MJ, et al The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. Science 2006; 313:1929-35.
    • (2006) Science , vol.313 , pp. 1929-1935
    • Lamb, J.1    Crawford, E.D.2    Peck, D.3    Modell, J.W.4    Blat, I.C.5    Wrobel, M.J.6
  • 33
    • 47049105891 scopus 로고    scopus 로고
    • Discovery of agents that eradicate Leukemia stem cells using an in silico screen of public gene expression data
    • Hassane DC, Guzman ML, Corbett C, Li X., Abboud R, Young F, et al Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data. Blood 2008; 111:5654-62.
    • (2008) Blood , vol.111 , pp. 5654-5662
    • Hassane, D.C.1    Guzman, M.L.2    Corbett, C.3    Li, X.4    Abboud, R.5    Young, F.6
  • 34
    • 78650635068 scopus 로고    scopus 로고
    • Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways
    • Hassane DC, Sen S, Minhajuddin M., Rossi RM, Corbett CA, Balys M, et al Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways. Blood 2010; 116:5983-90.
    • (2010) Blood , vol.116 , pp. 5983-5990
    • Hassane, D.C.1    Sen, S.2    Minhajuddin, M.3    Rossi, R.M.4    Corbett, C.A.5    Balys, M.6
  • 35
    • 33749433916 scopus 로고    scopus 로고
    • Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
    • Hieronymus H, Lamb J, Ross K.N., Peng XP, Clement C, Rodina A, et al Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators. Cancer Cell 2006; 10:321-30.
    • (2006) Cancer Cell , vol.10 , pp. 321-330
    • Hieronymus, H.1    Lamb, J.2    Ross, K.N.3    Peng, X.P.4    Clement, C.5    Rodina, A.6
  • 36
    • 1442335997 scopus 로고    scopus 로고
    • Gene expression-based high-throughput screening(GE-HTS) and application to Leukemia differentiation
    • Stegmaier K, Ross KN, Colavito S.A., O'Malley S, Stockwell BR, Golub TR Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiation. Nat Genet 2004; 36:257-63.
    • (2004) Nat Genet , vol.36 , pp. 257-263
    • Stegmaier, K.1    Ross, K.N.2    Colavito, S.A.3    O'Malley, S.4    Stockwell, B.R.5    Golub, T.R.6
  • 37
    • 34247478069 scopus 로고    scopus 로고
    • Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in ewing sarcoma
    • Stegmaier K, Wong JS, Ross K.N., Chow KT, Peck D, Wright RD, et al Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma. PLoS Med 2007; 4:e122.
    • (2007) PLoS Med , vol.4
    • Stegmaier, K.1    Wong, J.S.2    Ross, K.N.3    Chow, K.T.4    Peck, D.5    Wright, R.D.6
  • 38
    • 33749443714 scopus 로고    scopus 로고
    • Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance
    • Wei G, Twomey D, Lamb J., Schlis K, Agarwal J, Stam R.W., et al Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance. Cancer Cell 2006; 10: 331-42.
    • (2006) Cancer Cell , vol.10 , pp. 331-342
    • Wei, G.1    Twomey, D.2    Lamb, J.3    Schlis, K.4    Agarwal, J.5    Stam, R.W.6
  • 40
    • 0141869078 scopus 로고    scopus 로고
    • The RAS signal transduction pathway and its role in radiation sensitivity
    • McKenna WG, Muschel RJ, Gupta A.K., Hahn SM, Bernhard EJ The RAS signal transduction pathway and its role in radiation sensitivity. Oncogene 2003; 22:5866-75.
    • (2003) Oncogene , vol.22 , pp. 5866-5875
    • McKenna, W.G.1    Muschel, R.J.2    Gupta, A.K.3    Hahn, S.M.4    Bernhard, E.J.5
  • 41
    • 84863764614 scopus 로고    scopus 로고
    • Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming
    • Mitsuishi Y, Taguchi K, Kawatani Y., Shibata T, Nukiwa T, Aburatani H., et al Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. Cancer Cell 2012; 22:66-79.
    • (2012) Cancer Cell , vol.22 , pp. 66-79
    • Mitsuishi, Y.1    Taguchi, K.2    Kawatani, Y.3    Shibata, T.4    Nukiwa, T.5    Aburatani, H.6
  • 42
    • 70449091786 scopus 로고    scopus 로고
    • Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1
    • Barbie DA, Tamayo P, Boehm J.S., Kim SY, Moody SE, Dunn IF, et al Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature 2009; 462:108-12.
    • (2009) Nature , vol.462 , pp. 108-112
    • Barbie, D.A.1    Tamayo, P.2    Boehm, J.S.3    Kim, S.Y.4    Moody, S.E.5    Dunn, I.F.6
  • 44
    • 84862636275 scopus 로고    scopus 로고
    • Mutant p53: One name, many proteins
    • Freed-Pastor W.A., Prives C. Mutant p53: one name, many proteins. Genes Dev 2012; 26:1268-86.
    • (2012) Genes Dev , vol.26 , pp. 1268-1286
    • Freed-Pastor, W.A.1    Prives, C.2
  • 45
    • 0033118475 scopus 로고    scopus 로고
    • Apoptosis, p53, and tumor cell sensitivity to anticancer agents
    • Brown JM, Wouters BG Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res 1999; 59:1391-9.
    • (1999) Cancer Res , vol.59 , pp. 1391-1399
    • Brown, J.M.1    Wouters, B.G.2
  • 46
    • 0030220290 scopus 로고    scopus 로고
    • Cell density dependent plating efficiency affects outcome and interpretation of colony forming assays
    • Pomp J, Wike JL, Ouwerkerk I.J., Hoogstraten C., Davelaar J, Schrier PI, et al Cell density dependent plating efficiency affects outcome and interpretation of colony forming assays. Radiother Oncol 1996; 40: 121-5.
    • (1996) Radiother Oncol , vol.40 , pp. 121-125
    • Pomp, J.1    Wike, J.L.2    Ouwerkerk, I.J.3    Hoogstraten, C.4    Davelaar, J.5    Schrier, P.I.6
  • 47
    • 84860532031 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the lung: Molecular subtypes and therapeutic opportunities
    • Perez-Moreno P., Brambilla E, Thomas R., Soria JC Squamous cell carcinoma of the lung: molecular subtypes and therapeutic opportunities. Clin Cancer Res 2012; 18:2443-51.
    • (2012) Clin Cancer Res , vol.18 , pp. 2443-2451
    • Perez-Moreno, P.1    Brambilla, E.2    Thomas, R.3    Soria, J.C.4
  • 48
    • 0031701801 scopus 로고    scopus 로고
    • The prognostic significance of immunohistochemically detected p53 protein expression in non-small cell lung cancer treated with radiation therapy
    • Hayakawa K, Mitsuhashi N, Hasegawa M., Saito Y, Sakurai H, Ohno T., et al The prognostic significance of immunohistochemically detected p53 protein expression in non-small cell lung cancer treated with radiation therapy. Anticancer Res 1998; 18:3685-8.
    • (1998) Anticancer Res , vol.18 , pp. 3685-3688
    • Hayakawa, K.1    Mitsuhashi, N.2    Hasegawa, M.3    Saito, Y.4    Sakurai, H.5    Ohno, T.6
  • 49
    • 0034254197 scopus 로고    scopus 로고
    • Cell proliferation and apoptosis in stage III inoperable non-small cell lung carcinoma treated by radiotherapy
    • Langendijk H, Thunnissen E, Arends J.W., de Jong J, ten Velde G, Lamers R, et al Cell proliferation and apoptosis in stage III inoperable non-small cell lung carcinoma treated by radiotherapy. Radiother Oncol 2000; 56:197-207.
    • (2000) Radiother Oncol , vol.56 , pp. 197-207
    • Langendijk, H.1    Thunnissen, E.2    Arends, J.W.3    De Jong, J.4    Ten Velde, G.5    Lamers, R.6
  • 50
    • 0032993768 scopus 로고    scopus 로고
    • P53 mutations predict non-small cell lung carcinoma response to radiotherapy
    • Matsuzoe D, Hideshima T, Kimura A., Inada K, Watanabe K, Akita Y., et al p53 mutations predict non-small cell lung carcinoma response to radiotherapy. Cancer Lett 1999; 135:189-94.
    • (1999) Cancer Lett , vol.135 , pp. 189-194
    • Matsuzoe, D.1    Hideshima, T.2    Kimura, A.3    Inada, K.4    Watanabe, K.5    Akita, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.