Molecular docking studies for the identification of novel melatoninergic inhibitors for acetylserotonin-O-methyltransferase using different docking routines

Theoretical Biology and Medical Modelling

Volumn 10, Issue 1, 2013, Pages

  Azam, Syed Sikander ^a   Abbasi, Sumra Wajid ^a  

^a QUAID I AZAM UNIVERSITY   (Pakistan)

Author keywords

Acetylserotonin O methyltransferase; Binding affinities; Bipolar disorders; Melatoninergic inhibitors; Molecular docking; Pineal parenchymal tumors

Indexed keywords

VALERIANA;

ACETYLSEROTONIN METHYLTRANSFERASE; ENZYME INHIBITOR; LIGAND; MELATONIN;

ARTICLE; BIOCATALYSIS; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVE SITE; HUMAN; IC 50; METABOLISM; MOLECULAR DOCKING; THERMODYNAMICS; TIME;

ACETYLSEROTONIN O-METHYLTRANSFERASE; BIOCATALYSIS; CATALYTIC DOMAIN; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; LIGANDS; MELATONIN; MOLECULAR DOCKING SIMULATION; THERMODYNAMICS; TIME FACTORS;

EID: 84885994459     PISSN: None     EISSN: 17424682     Source Type: Journal    
DOI: 10.1186/1742-4682-10-63     Document Type: Article

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