N-acetyl lysyltyrosylcysteine amide inhibits myeloperoxidase, a novel tripeptide inhibitor

Journal of Lipid Research

Volumn 54, Issue 11, 2013, Pages 3016-3029

  Zhang, Hao ^a   Jing, Xigang ^a   Shi, Yang ^a,c   Xu, Hao ^a   Du, Jianhai ^a   Guan, Tongju ^a   Weihrauch, Dorothee ^a   Jones, Deron W ^a   Wang, Weiling ^b   Gourlay, David ^a   Oldham, Keith T ^a   Hillery, Cheryl A ^a   Pritchard Jr , Kirkwood A ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b SHANDONG UNIVERSITY   (China)

^c AURORA HEALTH CARE   (United States)

Author keywords

Apolipoprotein A1; Chlorination; Hypochlorous acid; Lipid peroxidation; Low density lipoproteins; Nitration; Nitrogen dioxide

Indexed keywords

HEME; LOW DENSITY LIPOPROTEIN; MYELOPEROXIDASE; N ACETYL LYSYLTROSYLCYSTEINE AMIDE; OXIDOREDUCTASE INHIBITOR; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BOVINE AORTIC ENDOTHELIAL CELL; CELL PROTECTION; CELL STRAIN HL 60; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG BINDING; DRUG MECHANISM; DRUG STRUCTURE; ENDOTHELIUM CELL; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MOLECULAR DOCKING; NEUTROPHIL; NITRATION; NONHUMAN; OXIDATION KINETICS; PRIORITY JOURNAL;

APOLIPOPROTEIN A1; CHLORINATION; HYPOCHLOROUS ACID; LIPID PEROXIDATION; LOW DENSITY LIPOPROTEINS; NITRATION; NITROGEN DIOXIDE;

ANIMALS; AORTA; BIOCATALYSIS; CATTLE; ENDOTHELIAL CELLS; HALOGENATION; HL-60 CELLS; HUMANS; HYPOCHLOROUS ACID; LIPID PEROXIDATION; NEUTROPHILS; NITRATES; OLIGOPEPTIDES; OXIDATION-REDUCTION; PEROXIDASE;

EID: 84885993885     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M038273     Document Type: Article

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