Inhibition of myeloperoxidase-catalyzed tyrosylation by phenolic antioxidants in vitro

Bioscience, Biotechnology and Biochemistry

Volumn 67, Issue 5, 2003, Pages 1136-1139

  Kato, Yoji ^a   Nagao, Akihiko ^b   Terao, Junji ^c   Osawa, Toshihiko ^d  

^a UNIVERSITY OF HYOGO   (Japan)

^b NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d NAGOYA UNIVERSITY   (Japan)

Author keywords

Dityrosine; Myeloperoxidase; Phenolic antioxidants; Polyphenol

Indexed keywords

ANTIOXIDANT; BUFFER; COUMARIC ACID; CURCUMIN; DITYROSINE; DRUG DERIVATIVE; ENZYME INHIBITOR; FERULIC ACID; GALLIC ACID; PEROXIDASE; PHENOL DERIVATIVE; QUERCETIN; TYROSINE;

ARTICLE; DRUG ANTAGONISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; SPECTROFLUOROMETRY;

ANTIOXIDANTS; BUFFERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARIC ACIDS; CURCUMIN; ENZYME INHIBITORS; GALLIC ACID; PEROXIDASE; PHENOLS; QUERCETIN; SPECTROMETRY, FLUORESCENCE; TYROSINE;

EID: 1042294935     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.67.1136     Document Type: Article

References (12)

1. Domigan, N. M., Charlton, T. S., Duncan, M. W., Winterbourn, C. C., and Kettle, A. J., Chlorination of tyrosyl residues in peptides by myeloperoxidase and human neutrophils. J. Biol. Chem., 270, 16542-16548 (1995).
2. Heinecke, J. W., Li, W., Daehnke, M. L., and Goldstein, J. A., Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages. J. Biol. Chem., 268, 4069-4077 (1993).
3. Heinecke, J. W., Tyrosyl radical production by myeloperoxidase: a phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins. Toxicology, 177, 11-22 (2002).
4. Savenkova, M. I., Mueller, D. M., and Heinecke, J. W., Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein. J. Biol. Chem., 269, 20394-20400 (1994).
5. Francis, G. A., Mendez, A. J., Bierman, E. L., and Heinecke, J. W., Oxidative tyrosylation of high density lipoprotein by peroxidase enhances cholesterol removal from cultured fibroblats and macrophage foam cells. Proc. Natl. Acad. Sci. USA, 90, 6631-6635 (1993).
6. Sugiyama, Y., Kawakishi, S., and Osawa, T., Involvement of the beta-diketone moiety in the antioxidative mechanism of tetrahydrocurcumin. Biochem. Pharmacol., 52, 519-525 (1996).
7. Kato, Y., Uchida, K., and Kawakishi, S., Aggregation of collagen exposed to UVA in the presence of riboflavin: a plausible role of tyrosine modification. Photochem. Photobiol., 59, 343-349 (1994).
8. 2-tyrosine system. Biochem. Biophys. Res. Commun., 125, 916-918 (1984).
9. Sampson, J. B., Ye, Y.-Z., Rosen, H., and Beckman, J. S., Myeloperoxidase and horseradish peroxidase catalyze tyrosine nitration in proteins from nitrite and hydrogen peroxide. Arch. Biochem. Biophys., 356, 207-213 (1998).
10. 2O2-chloride system of phagocytes, covalently modifies epsilon-amino groups of protein lysine residues. J. Biol. Chem., 272, 16990-16998 (1997).
11. Zuckerman, S. H., and Bryan, N., Inhibition of LDL oxidation and myeloperoxidase dependent tyrosyl radical formation by the selective estrogen receptor modulator raloxifene (LY139481 HCL). Atherosclerosis, 126, 65-75 (1996).
12. Tsuda, T., Horio, F., Kato, Y., and Osawa, T., Cyanidin 3-O-b-D-glucoside attenuates the hepatic ischemia-reperfusion injury through a decrease in the neutrophil chemoattractant producion in rats. J. Nutr. Sci. Vitaminol., 48, 134-141 (2002)