Isoniazid as a substrate and inhibitor of myeloperoxidase: Identification of amine adducts and the influence of superoxide dismutase on their formation

Biochemical Pharmacology

Volumn 84, Issue 7, 2012, Pages 949-960

  Forbes, Louisa V ^a   Furtmüller, Paul G ^b   Khalilova, Irada ^a   Turner, Rufus ^a   Obinger, Christian ^b   Kettle, Anthony J ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

Isoniazid; Myeloperoxidase; Neutrophils; Oxidation; Superoxide dismutase

Indexed keywords

AMINE; CHLORIDE; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; ISONIAZID; METHIONINE; MYELOPEROXIDASE; SUPEROXIDE DISMUTASE;

ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; DRUG OXIDATION; LUNG TUBERCULOSIS; NEUTROPHIL; PEROXIDATION; PRIORITY JOURNAL; TUBERCULOSIS;

AMINES; BENZIDINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HYDROGEN PEROXIDE; HYPOCHLOROUS ACID; IMMUNITY, INNATE; ISONIAZID; MASS SPECTROMETRY; MOLECULAR STRUCTURE; NEUTROPHILS; OXIDATION-REDUCTION; PEROXIDASE; SUPEROXIDE DISMUTASE;

EID: 84865469048     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.07.020     Document Type: Article

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