Kinetics of the reactions of nitrogen dioxide with glutathione, cysteine, and uric acid at physiological pH

Free Radical Biology and Medicine

Volumn 32, Issue 12, 2002, Pages 1314-1323

  Ford, Eleonora ^a   Hughes, Martin N ^b   Wardman, Peter ^a  

^a MOUNT VERNON HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cysteine; Free radicals; Glutathione; Kinetics; Nitrogen dioxide; Pulse radiolysis; Urate

Indexed keywords

2,2' AZINOBIS(3 ETHYLTHIAZOLINE 6 SULFONIC ACID); CYSTEINE; GLUTATHIONE PEROXIDASE; NITROGEN DIOXIDE; SULFONIC ACID DERIVATIVE; THIOL DERIVATIVE; UNCLASSIFIED DRUG; URATE; URIC ACID; FREE RADICAL; GLUTATHIONE;

ARTICLE; CONCENTRATION (PARAMETERS); CYTOPLASM; CYTOSOL; DISSOCIATION CONSTANT; KINETICS; OXIDATION; PH; PLASMA; PRIORITY JOURNAL; PULSE RADIOLYSIS; SPECTROPHOTOMETRY; METABOLISM;

CYSTEINE; FREE RADICALS; GLUTATHIONE; HYDROGEN-ION CONCENTRATION; KINETICS; NITROGEN DIOXIDE; PULSE RADIOLYSIS; SUPPORT, NON-U.S. GOV'T; URIC ACID;

MUS;

EID: 0037096198     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00850-X     Document Type: Article

References (66)

1. 2 radicals
2. The complex chemistry of peroxynitrite decomposition: New insights
3. Mechanisms of peroxynitrite oxidations and rearrangements: The theoretical perspective
4. 2-catalyzed one-electron oxidations by peroxynitrite: Properties of the reactive intermediate
5. Direct EPR detection of the carbonate radical anion produced from peroxynitrite and carbon dioxide
6. Unraveling peroxynitrite formation in biological systems
7. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils
8. Nitrogen dioxide radical generated by the myeloperoxidase-hydrogen peroxide-nitrite system promotes lipid peroxidation of low density lipoprotein
9. -): An EPR and spin trapping study
10. Mechanism of reaction of myeloperoxidase with nitrite
11. 2 within the hydrophobic interior of biological membranes
12. An autocatalytic mechanism of protein nitrosylation
13. Nitrogen dioxide in biology: Correlating chemical kinetics with biological effects
14. Reactions of nitrogen dioxide in aqueous model systems: Oxidation of tyrosine units in peptides and proteins
15. Nitrogen dioxide and related free radicals: Electron-transfer reactions with organic compounds in solutions containing nitrite or nitrate
16. Antioxidation mechanisms of uric acid
17. The radiation chemistry of nitrite ion in aqueous solution
18. 2 in wässriger Lösung
19. Free-radical intermediates and stable products in the oxidation of indole-3-acetic acid
20. 4 in aqueous solution
21. - radical
22. The steady-state kinetics of peroxidase with 2,2′-azino-di-(3-ethylbenzthiazoline-6-sulphonic acid) as chromogen
23. Radical cations as reference chromogens in kinetic studies of one-electron transfer reactions: Pulse radiolysis studies of 2,2′-azinobis-(3-ethylbenzthiazoline-6-sulphonate)
24. Generation of thiyl radical by nitric oxide: A spin trapping study
25. Carbon dioxide stimulates the production of thiyl, sulfinyl, and disulfide radical anion from thiol oxidation by peroxynitrite
26. Nuclear magnetic resonance studies of the acid-base chemistry of amino acids and peptides. I. Microscopic ionization constants of glutathione and methylmercury-complexed glutathione
27. Synthese, Struktur und Eigenschaften der Harnsäure sowie ihrer N-Methylderivate
28. Superoxide as an intracellular radical sink
29. Reactions of thiyl radicals
30. Rate constant determination for the reaction of hydroxyl and glutathione thiyl radicals with glutathione in aqueous solution
31. 3 groups
32. •-, mediating electron transfer to Fe(III)-cytochrome
33. Intramolecular transformation reaction of the glutathione thiyl radical into a non-sulphur-centred radical: A pulse radiolysis and EPR study
34. Vitamin E analogue Trolox C. E.s.r. and pulse-radiolysis studies of free-radical reactions
35. Hepatic mitochondrial and cytosolic glutahione content and the subcellular distribution of GSH-S-transferases
36. Towards the physiological function of uric acid
37. Simultaneous determination of two antioxidants, uric and ascorbic acid, in animal tissue by high-performance liquid chromatography
38. Influence of plasma glutathione levels on radiation mucositis
39. Temperature dependence of the rate constants for reaction of inorganic radicals with organic reductants
40. Profiles of antioxidants in human plasma
41. Distribution of ascorbic acid, metabolites and analogues in man and animals
42. Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate
43. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase
44. Tyrosine modification by reactive nitrogen species: A closer look
45. Oxidative damage and tyrosine nitration from peroxynitrite
46. •- under physiological conditions. How the radicals do the job
47. The biological chemistry of peroxynitrite
48. 2 at basic pH
49. • in aqueous solution
50. Thiyl free radicals: Direct observations of electron transfer reactions with phenothiazines and ascorbate
51. Kinetic factors that control the fate of thiyl radicals in cells
52. Evaluation of the 'radical sink' hypothesis from a chemical-kinetic viewpoint
53. Thiyl radicals in biology: Their role as a 'molecular switch' central to cellular oxidative stress
54. Nitrogen dioxide depletes uric acid and ascorbic acid but not glutathione from lung lining fluid
55. Cell type and spatial location dependence of cytoplasmic viscosity measured by time-resolved fluorescence microscopy
56. Determinants of the translational mobility of a small solute in cell cytoplasm
57. Molecular mobility and nucleocytoplasmic flux in hepatoma cells
58. Translational diffusion of macromolecule-sized solutes in cytoplasm and nucleus
59. Kinetics of N-nitrosation in oxygenated nitric oxide solutions at physiological pH: Role of nitrous anhydride and effects of phosphate and chloride
60. Kinetics of S-nitrosation of thiols in nitric oxide solutions
61. Scavenging of nitrogen dioxide, thiyl and sulfonyl free radicals by the nutritional antioxidant β-carotene