Comparison of the binding and reactivity of plant and mammalian peroxidases to indole derivatives by computational docking

Biochemistry

Volumn 45, Issue 9, 2006, Pages 2940-2950

  Hallingbäck, Henrik R ^b,c   Gabdoulline, Razif R ^a   Wade, Rebecca C ^a  

^a EML Research   (Germany)

^b UPPSALA UNIVERSITY   (Sweden)

^c SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; BIOSYNTHESIS; CATALYSIS; ENZYMES; OXIDATION; PROTEINS; SUBSTRATES;

COMPUTATIONAL DOCKING; DOCKING PROCEDURE; HORSERADISH PEROXIDASE; HRP AND MPO; MELATONIN AND SEROTONIN; MELATONIN BY THE MAMMALIAN; MYELOPEROXIDASE; OXYGEN SPECIES;

CHEMICAL REACTIONS;

HEME; HEME DERIVATIVE; HEME PEROXIDASE; HORSERADISH PEROXIDASE; INDOLE DERIVATIVE; MELATONIN; PEROXIDASE; SEROTONIN; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CALCULATION; COMPARATIVE STUDY; COMPUTATIONAL DOCKING; CONTROLLED STUDY; DRUG DESIGN; ENZYME BINDING; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; MAMMAL; MOLECULAR MODEL; NONHUMAN; OXIDATION; PLANT; PRIORITY JOURNAL; REACTION ANALYSIS; SPECIES DIFFERENCE; VALIDATION PROCESS;

ANIMALS; BINDING SITES; COUMARIC ACIDS; ELECTROSTATICS; HEME; HORSERADISH PEROXIDASE; HYDROXAMIC ACIDS; INDOLES; KINETICS; MAMMALS; MELATONIN; MODELS, MOLECULAR; PEROXIDASE; PEROXIDASES; PLANTS; PROTEIN BINDING; SEROTONIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ARMORACIA RUSTICANA; MAMMALIA; RUMEX;

EID: 33644671184     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi051510e     Document Type: Article

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