메뉴 건너뛰기




Volumn 4, Issue SEP, 2013, Pages

Afferent neuronal control of type-I gonadotropin releasing hormone neurons in the human

Author keywords

Afferent; GnRH neurons; Humans; Hypothalamus; Infundibular nucleus; Kisspeptin; LHRH; Reproduction

Indexed keywords


EID: 84885969095     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2013.00130     Document Type: Review
Times cited : (34)

References (233)
  • 1
    • 0017185519 scopus 로고
    • Pituitary stalk portal blood collection in rhesus monkeys:evidence for pulsatile release of gonadotropin-releasing hormone (GnRH)
    • doi:10.1210/endo-99-1-243
    • Carmel PW, Araki S, Ferin M. Pituitary stalk portal blood collection in rhesus monkeys:evidence for pulsatile release of gonadotropin-releasing hormone (GnRH). Endocrinology (1976) 99(1):243-8. doi:10.1210/endo-99-1-243.
    • (1976) Endocrinology , vol.99 , Issue.1 , pp. 243-248
    • Carmel, P.W.1    Araki, S.2    Ferin, M.3
  • 2
    • 0020211729 scopus 로고
    • The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized ewes
    • doi:10.1210/endo-111-5-1737
    • Clarke IJ, Cummins JT. The temporal relationship between gonadotropin releasing hormone (GnRH) and luteinizing hormone (LH) secretion in ovariectomized ewes. Endocrinology (1982) 111(5):1737-9. doi:10.1210/endo-111-5-1737.
    • (1982) Endocrinology , vol.111 , Issue.5 , pp. 1737-1739
    • Clarke, I.J.1    Cummins, J.T.2
  • 3
    • 0018168286 scopus 로고
    • Hypophysial responses to continuous and intermittent delivery of hypothalamic gonadotropin-releasing hormone
    • doi:10.1126/science.100883
    • Belchetz PE, Plant TM, Nakai Y, Keogh EJ, Knobil E. Hypophysial responses to continuous and intermittent delivery of hypothalamic gonadotropin-releasing hormone. Science (1978) 202(4368):631-3. doi:10.1126/science.100883.
    • (1978) Science , vol.202 , Issue.4368 , pp. 631-633
    • Belchetz, P.E.1    Plant, T.M.2    Nakai, Y.3    Keogh, E.J.4    Knobil, E.5
  • 4
    • 0035164342 scopus 로고    scopus 로고
    • Development of luteinizing hormone releasing hormone neurones
    • doi:10.1046/j.1365-2826.2001.00609.x
    • Wray S. Development of luteinizing hormone releasing hormone neurones. J Neuroendocrinol (2001) 13(1):3-11. doi:10.1046/j.1365-2826.2001.00609.x.
    • (2001) J Neuroendocrinol , vol.13 , Issue.1 , pp. 3-11
    • Wray, S.1
  • 5
    • 0024554568 scopus 로고
    • Origin of luteinizing hormone-releasing hormone neurons
    • doi:10.1038/338161a0
    • Schwanzel-Fukuda M, PfaffDW. Origin of luteinizing hormone-releasing hormone neurons. Nature (1989) 338(6211):161-4. doi:10.1038/338161a0.
    • (1989) Nature , vol.338 , Issue.6211 , pp. 161-164
    • Schwanzel-Fukuda, M.1    Pfaff, D.W.2
  • 6
    • 0024470630 scopus 로고
    • Luteinizing hormone-releasing hormone (LHRH)-expressing cells do not migrate normally in an inherited hypogonadal (Kallmann) syndrome
    • doi:10.1016/0169-328X(89)90076-4
    • Schwanzel-Fukuda M, Bick D, PfaffDW. Luteinizing hormone-releasing hormone (LHRH)-expressing cells do not migrate normally in an inherited hypogonadal (Kallmann) syndrome. Brain Res Mol Brain Res (1989) 6(4):311-26. doi:10.1016/0169-328X(89)90076-4.
    • (1989) Brain Res Mol Brain Res , vol.6 , Issue.4 , pp. 311-326
    • Schwanzel-Fukuda, M.1    Bick, D.2    Pfaff, D.W.3
  • 7
    • 0018955352 scopus 로고
    • The preoptico-infundibular LH-RH tract of the rat
    • doi:10.1016/0006-8993(80)90344-3
    • Merchenthaler I, Kovacs G, Lavasz G, Setalo G. The preoptico-infundibular LH-RH tract of the rat. Brain Res (1980) 198(1):63-74. doi:10.1016/0006-8993(80)90344-3.
    • (1980) Brain Res , vol.198 , Issue.1 , pp. 63-74
    • Merchenthaler, I.1    Kovacs, G.2    Lavasz, G.3    Setalo, G.4
  • 8
    • 0017230186 scopus 로고
    • Immunohistological study of the origin of LH-RH-containing nerve fibers of the rat hypothalamus
    • doi:10.1016/0006-8993(76)90462-5
    • Setalo G, Vigh S, Schally AV, Arimura A, Flerko B. Immunohistological study of the origin of LH-RH-containing nerve fibers of the rat hypothalamus. Brain Res (1976) 103(3):597-602. doi:10.1016/0006-8993(76)90462-5.
    • (1976) Brain Res , vol.103 , Issue.3 , pp. 597-602
    • Setalo, G.1    Vigh, S.2    Schally, A.V.3    Arimura, A.4    Flerko, B.5
  • 9
    • 0022589138 scopus 로고
    • Immunocytochemical localization of luteinizing hormone-releasing hormone (LHRH) pathways in the sheep brain during anestrus and the mid-luteal phase of the estrous cycle
    • doi:10.1002/cne.902440103
    • Lehman MN, Robinson JE, Karsch FJ, Silverman AJ. Immunocytochemical localization of luteinizing hormone-releasing hormone (LHRH) pathways in the sheep brain during anestrus and the mid-luteal phase of the estrous cycle. J Comp Neurol (1986) 244(1):19-35. doi:10.1002/cne.902440103.
    • (1986) J Comp Neurol , vol.244 , Issue.1 , pp. 19-35
    • Lehman, M.N.1    Robinson, J.E.2    Karsch, F.J.3    Silverman, A.J.4
  • 10
    • 0017129509 scopus 로고
    • Distribution of luteinizing hormone-releasing hormone (LHRH) in the guinea pig brain
    • doi:10.1210/endo-99-1-30
    • Silverman AJ. Distribution of luteinizing hormone-releasing hormone (LHRH) in the guinea pig brain. Endocrinology (1976) 99(1):30-41. doi:10.1210/endo-99-1-30.
    • (1976) Endocrinology , vol.99 , Issue.1 , pp. 30-41
    • Silverman, A.J.1
  • 11
    • 0021267757 scopus 로고
    • LHRH neurons and their projections in humans and other mammals:species comparisons
    • doi:10.1016/0196-9781(84)90277-8
    • King JC, Anthony EL. LHRH neurons and their projections in humans and other mammals:species comparisons. Peptides (1984) 5(Suppl 1):195-207. doi:10.1016/0196-9781(84)90277-8.
    • (1984) Peptides , vol.5 , Issue.SUPPL. 1 , pp. 195-207
    • King, J.C.1    Anthony, E.L.2
  • 12
    • 0028144394 scopus 로고
    • Topography of neurons expressing luteinizing hormone-releasing hormone gene transcripts in the human hypothalamus and basal forebrain
    • doi:10.1002/cne.903390408
    • Rance NE, Young WS III, McMullen NT. Topography of neurons expressing luteinizing hormone-releasing hormone gene transcripts in the human hypothalamus and basal forebrain. J Comp Neurol (1994) 339(4):573-86. doi:10.1002/cne.903390408.
    • (1994) J Comp Neurol , vol.339 , Issue.4 , pp. 573-586
    • Rance, N.E.1    Young I.I.I, W.S.2    McMullen, N.T.3
  • 13
    • 0001373043 scopus 로고
    • Characterization and topography of LH-RH neurons in the human brain
    • doi:10.1016/0304-3940(76)90056-2
    • Barry J. Characterization and topography of LH-RH neurons in the human brain. Neurosci Lett (1976) 3(5-6):287-91. doi:10.1016/0304-3940(76)90056-2.
    • (1976) Neurosci Lett , vol.3 , Issue.5-6 , pp. 287-291
    • Barry, J.1
  • 14
    • 0025836522 scopus 로고
    • Computer-assisted mapping of immunoreactive mammalian gonadotropin-releasing hormone in adult human basal forebrain and amygdala
    • doi:10.1210/endo-128-6-3199
    • Stopa EG, Koh ET, Svendsen CN, Rogers WT, Schwaber JS, King JC. Computer-assisted mapping of immunoreactive mammalian gonadotropin-releasing hormone in adult human basal forebrain and amygdala. Endocrinology (1991) 128(6):3199-207. doi:10.1210/endo-128-6-3199.
    • (1991) Endocrinology , vol.128 , Issue.6 , pp. 3199-3207
    • Stopa, E.G.1    Koh, E.T.2    Svendsen, C.N.3    Rogers, W.T.4    Schwaber, J.S.5    King, J.C.6
  • 15
    • 0034722849 scopus 로고    scopus 로고
    • Topography and associations of luteinizing hormone-releasing hormone and neuropeptide Y-immunoreactive neuronal systems in the human diencephalon
    • doi:10.1002/1096-9861(20001127)427:4<593::AID-CNE7>3.0.CO;2-C
    • Dudas B, Mihaly A, Merchenthaler I. Topography and associations of luteinizing hormone-releasing hormone and neuropeptide Y-immunoreactive neuronal systems in the human diencephalon. J Comp Neurol (2000) 427(4):593-603. doi:10.1002/1096-9861(20001127)427:4<593::AID-CNE7>3.0.CO;2-C.
    • (2000) J Comp Neurol , vol.427 , Issue.4 , pp. 593-603
    • Dudas, B.1    Mihaly, A.2    Merchenthaler, I.3
  • 16
    • 0017755731 scopus 로고
    • Immunofluorescence study of LRF neurons in man
    • doi:10.1007/BF00222770
    • Barry J. Immunofluorescence study of LRF neurons in man. Cell Tissue Res (1977) 181(1):1-14. doi:10.1007/BF00222770.
    • (1977) Cell Tissue Res , vol.181 , Issue.1 , pp. 1-14
    • Barry, J.1
  • 17
    • 0018355201 scopus 로고
    • A comparative study of the luteinizing hormone releasing hormone (LHRH) neuronal networks in mammals
    • Silverman AJ, Krey LC, Zimmerman EA. A comparative study of the luteinizing hormone releasing hormone (LHRH) neuronal networks in mammals. Biol Reprod (1979) 20(1):98-110.
    • (1979) Biol Reprod , vol.20 , Issue.1 , pp. 98-110
    • Silverman, A.J.1    Krey, L.C.2    Zimmerman, E.A.3
  • 18
    • 0023195473 scopus 로고
    • GnRH-prohormone-containing neurons in the primate brain:immunostaining for the GnRH-associated peptide
    • doi:10.1016/0196-9781(87)90109-4
    • Song T, Nikolics K, Seeburg PH, Goldsmith PC. GnRH-prohormone-containing neurons in the primate brain:immunostaining for the GnRH-associated peptide. Peptides (1987) 8(2):335-46. doi:10.1016/0196-9781(87)90109-4.
    • (1987) Peptides , vol.8 , Issue.2 , pp. 335-346
    • Song, T.1    Nikolics, K.2    Seeburg, P.H.3    Goldsmith, P.C.4
  • 19
    • 0025284459 scopus 로고
    • Immunocytochemical demonstration of GAP-like immunoreactive neuronal elements in the human hypothalamus and pituitary
    • doi:10.1007/BF02440178
    • Abe J, Okamura H, Ibata Y, Motoyama A, Wakabayashi I, Ling N, et al. Immunocytochemical demonstration of GAP-like immunoreactive neuronal elements in the human hypothalamus and pituitary. Histochemistry (1990) 94(2):127-33. doi:10.1007/BF02440178.
    • (1990) Histochemistry , vol.94 , Issue.2 , pp. 127-133
    • Abe, J.1    Okamura, H.2    Ibata, Y.3    Motoyama, A.4    Wakabayashi, I.5    Ling, N.6
  • 20
    • 0026579461 scopus 로고
    • Immunohistochemical detection of proluteinizing hormone-releasing hormone peptides in neurons in the human hypothalamus
    • doi:10.1210/jc.74.1.135
    • Bloch B, Gaillard RC, Culler MD, Negro-Vilar A. Immunohistochemical detection of proluteinizing hormone-releasing hormone peptides in neurons in the human hypothalamus. J Clin Endocrinol Metab (1992) 74(1):135-8. doi:10.1210/jc.74.1.135.
    • (1992) J Clin Endocrinol Metab , vol.74 , Issue.1 , pp. 135-138
    • Bloch, B.1    Gaillard, R.C.2    Culler, M.D.3    Negro-Vilar, A.4
  • 21
    • 0017686665 scopus 로고
    • Immunofluorescence study of LH-RH producing cells in the human fetal hypothalamus
    • doi:10.1007/BF00219769
    • Paulin C, Dubois MP, Barry J, Dubois PM. Immunofluorescence study of LH-RH producing cells in the human fetal hypothalamus. Cell Tissue Res (1977) 182(3):341-5. doi:10.1007/BF00219769.
    • (1977) Cell Tissue Res , vol.182 , Issue.3 , pp. 341-345
    • Paulin, C.1    Dubois, M.P.2    Barry, J.3    Dubois, P.M.4
  • 22
    • 0021298482 scopus 로고
    • Immunocytochemical localization of LHRH in the median eminence, infundibular stalk, and neurohypophysis. Evidence for multiple sites of releasing hormone secretion in humans and other mammals
    • doi:10.1007/BF00216506
    • Anthony EL, King JC, Stopa EG. Immunocytochemical localization of LHRH in the median eminence, infundibular stalk, and neurohypophysis. Evidence for multiple sites of releasing hormone secretion in humans and other mammals. Cell Tissue Res (1984) 236(1):5-14. doi:10.1007/BF00216506.
    • (1984) Cell Tissue Res , vol.236 , Issue.1 , pp. 5-14
    • Anthony, E.L.1    King, J.C.2    Stopa, E.G.3
  • 23
    • 0021927908 scopus 로고
    • Luteinizing hormone-releasing hormone neurons in human preoptic/hypothalamus:differential intraneuronal localization of immunoreactive forms
    • doi:10.1210/jcem-60-1-88
    • King JC, Anthony EL, Fitzgerald DM, Stopa EG. Luteinizing hormone-releasing hormone neurons in human preoptic/hypothalamus:differential intraneuronal localization of immunoreactive forms. J Clin Endocrinol Metab (1985) 60(1):88-97. doi:10.1210/jcem-60-1-88.
    • (1985) J Clin Endocrinol Metab , vol.60 , Issue.1 , pp. 88-97
    • King, J.C.1    Anthony, E.L.2    Fitzgerald, D.M.3    Stopa, E.G.4
  • 24
    • 0025309007 scopus 로고
    • Anatomical distribution of LHRH-immunoreactive neurons in the human infant hypothalamus and extrahypothalamic regions
    • doi:10.1016/0006-8993(90)90929-6
    • Najimi M, Chigr F, Jordan D, Leduque P, Bloch B, Tommasi M, et al. Anatomical distribution of LHRH-immunoreactive neurons in the human infant hypothalamus and extrahypothalamic regions. Brain Res (1990) 516(2):280-91. doi:10.1016/0006-8993(90)90929-6.
    • (1990) Brain Res , vol.516 , Issue.2 , pp. 280-291
    • Najimi, M.1    Chigr, F.2    Jordan, D.3    Leduque, P.4    Bloch, B.5    Tommasi, M.6
  • 25
    • 33645874771 scopus 로고    scopus 로고
    • Three-dimensional representation of the neurotransmitter systems of the human hypothalamus:inputs of the gonadotrophin hormone-releasing hormone neuronal system
    • doi:10.1111/j.1365-2826.2005.01398.x
    • Dudas B, Merchenthaler I. Three-dimensional representation of the neurotransmitter systems of the human hypothalamus:inputs of the gonadotrophin hormone-releasing hormone neuronal system. J Neuroendocrinol (2006) 18(2):79-95. doi:10.1111/j.1365-2826.2005.01398.x.
    • (2006) J Neuroendocrinol , vol.18 , Issue.2 , pp. 79-95
    • Dudas, B.1    Merchenthaler, I.2
  • 26
    • 14244261469 scopus 로고    scopus 로고
    • Biocytin filling of adult gonadotropin-releasing hormone neurons in situ reveals extensive, spiny, dendritic processes
    • doi:10.1210/en.2004-1369
    • Campbell RE, Han SK, Herbison AE. Biocytin filling of adult gonadotropin-releasing hormone neurons in situ reveals extensive, spiny, dendritic processes. Endocrinology (2005) 146(3):1163-9. doi:10.1210/en.2004-1369.
    • (2005) Endocrinology , vol.146 , Issue.3 , pp. 1163-1169
    • Campbell, R.E.1    Han, S.K.2    Herbison, A.E.3
  • 27
    • 0014983464 scopus 로고
    • Vascularization of the posterior tuber in man and its relation to the tuber-hypophyseal vasculature
    • doi:10.1007/BF02310044
    • Duvernoy H, Koritke JG, Monnier G. Vascularization of the posterior tuber in man and its relation to the tuber-hypophyseal vasculature. J Neurovisc Relat (1971) 32(2):112-42. doi:10.1007/BF02310044.
    • (1971) J Neurovisc Relat , vol.32 , Issue.2 , pp. 112-142
    • Duvernoy, H.1    Koritke, J.G.2    Monnier, G.3
  • 28
    • 84866761591 scopus 로고    scopus 로고
    • Low degree of overlap between kisspeptin, neurokinin B, and dynorphin immunoreactivities in the infundibular nucleus of young male human subjects challenges the KNDy neuron concept
    • doi:10.1210/en.2012-1545
    • Hrabovszky E, Sipos MT, Molnar CS, CiofiP, Borsay BA, Gergely P, et al. Low degree of overlap between kisspeptin, neurokinin B, and dynorphin immunoreactivities in the infundibular nucleus of young male human subjects challenges the KNDy neuron concept. Endocrinology (2012) 153(10):4978-89. doi:10.1210/en.2012-1545.
    • (2012) Endocrinology , vol.153 , Issue.10 , pp. 4978-4989
    • Hrabovszky, E.1    Sipos, M.T.2    Molnar, C.S.3    Ciofi, P.4    Borsay, B.A.5    Gergely, P.6
  • 29
    • 0018170889 scopus 로고
    • Septo-epithalamo-habenular LRF-reactive neurons in monkeys
    • doi:10.1016/0006-8993(78)90962-9
    • Barry J. Septo-epithalamo-habenular LRF-reactive neurons in monkeys. Brain Res (1978) 151(1):183-7. doi:10.1016/0006-8993(78)90962-9.
    • (1978) Brain Res , vol.151 , Issue.1 , pp. 183-187
    • Barry, J.1
  • 30
    • 0020360213 scopus 로고
    • The luteinizing hormone-releasing hormone pathways in rhesus (Macaca mulatta) and pigtailed (Macaca nemestrina) monkeys:new observations on thick, unembedded sections
    • doi:10.1002/cne.902110309
    • Silverman AJ, Antunes JL, Abrams GM, Nilaver G, Thau R, Robinson JA, et al. The luteinizing hormone-releasing hormone pathways in rhesus (Macaca mulatta) and pigtailed (Macaca nemestrina) monkeys:new observations on thick, unembedded sections. J Comp Neurol (1982) 211(3):309-17. doi:10.1002/cne.902110309.
    • (1982) J Comp Neurol , vol.211 , Issue.3 , pp. 309-317
    • Silverman, A.J.1    Antunes, J.L.2    Abrams, G.M.3    Nilaver, G.4    Thau, R.5    Robinson, J.A.6
  • 31
    • 0016770970 scopus 로고
    • Immunofluorescence study of LRF neurons in primates
    • doi:10.1007/BF00218971
    • Barry J, Carette B. Immunofluorescence study of LRF neurons in primates. Cell Tissue Res (1975) 164(2):163-78. doi:10.1007/BF00218971.
    • (1975) Cell Tissue Res , vol.164 , Issue.2 , pp. 163-178
    • Barry, J.1    Carette, B.2
  • 32
    • 0022357354 scopus 로고
    • The LH-RH-containing neuronal network in the preoptic area of the rat:demonstration of LH-RH-containing nerve terminals in synaptic contact with LH-RH neurons
    • doi:10.1016/0006-8993(85)91011-X
    • Leranth C, Segura LM, Palkovits M, MacLusky NJ, Shanabrough M, Naftolin F. The LH-RH-containing neuronal network in the preoptic area of the rat:demonstration of LH-RH-containing nerve terminals in synaptic contact with LH-RH neurons. Brain Res (1985) 345(2):332-6. doi:10.1016/0006-8993(85)91011-X.
    • (1985) Brain Res , vol.345 , Issue.2 , pp. 332-336
    • Leranth, C.1    Segura, L.M.2    Palkovits, M.3    MacLusky, N.J.4    Shanabrough, M.5    Naftolin, F.6
  • 33
    • 0024340579 scopus 로고
    • Beta-endorphin and gonadotropin-releasing hormone synaptic input to gonadotropin-releasing hormone neurosecretory cells in the male rat
    • doi:10.1002/cne.902860106
    • Chen WP, Witkin JW, Silverman AJ. Beta-endorphin and gonadotropin-releasing hormone synaptic input to gonadotropin-releasing hormone neurosecretory cells in the male rat. J Comp Neurol (1989) 286(1):85-95. doi:10.1002/cne.902860106.
    • (1989) J Comp Neurol , vol.286 , Issue.1 , pp. 85-95
    • Chen, W.P.1    Witkin, J.W.2    Silverman, A.J.3
  • 34
    • 0023838623 scopus 로고
    • Infundibular gonadotropin-releasing hormone neurons are inhibited by direct opioid and autoregulatory synapses in juvenile monkeys
    • doi:10.1159/000124914
    • Thind KK, Goldsmith PC. Infundibular gonadotropin-releasing hormone neurons are inhibited by direct opioid and autoregulatory synapses in juvenile monkeys. Neuroendocrinology (1988) 47(3):203-16. doi:10.1159/000124914.
    • (1988) Neuroendocrinology , vol.47 , Issue.3 , pp. 203-216
    • Thind, K.K.1    Goldsmith, P.C.2
  • 35
    • 0035050231 scopus 로고    scopus 로고
    • Synchronized exocytotic bursts from gonadotropin-releasing hormone-expressing cells:dual control by intrinsic cellular pulsatility and gap junctional communication
    • doi:10.1210/en.142.5.2095
    • Vazquez-Martinez R, Shorte SL, Boockfor FR, Frawley LS. Synchronized exocytotic bursts from gonadotropin-releasing hormone-expressing cells:dual control by intrinsic cellular pulsatility and gap junctional communication. Endocrinology (2001) 142(5):2095-101. doi:10.1210/en.142.5.2095.
    • (2001) Endocrinology , vol.142 , Issue.5 , pp. 2095-2101
    • Vazquez-Martinez, R.1    Shorte, S.L.2    Boockfor, F.R.3    Frawley, L.S.4
  • 36
    • 0029091216 scopus 로고
    • Novel associations among gonadotropin-releasing hormone neurons
    • doi:10.1210/en.136.10.4323
    • Witkin JW, O'Sullivan H, Silverman AJ. Novel associations among gonadotropin-releasing hormone neurons. Endocrinology (1995) 136(10):4323-30. doi:10.1210/en.136.10.4323.
    • (1995) Endocrinology , vol.136 , Issue.10 , pp. 4323-4330
    • Witkin, J.W.1    O'Sullivan, H.2    Silverman, A.J.3
  • 37
    • 77954157770 scopus 로고    scopus 로고
    • Redefining the gonadotrophin-releasing hormone neurone dendrite
    • doi:10.1111/j.1365-2826.2010.02032.x
    • Campbell RE, Suter KJ. Redefining the gonadotrophin-releasing hormone neurone dendrite. J Neuroendocrinol (2010) 22(7):650-8. doi:10.1111/j.1365-2826.2010.02032.x.
    • (2010) J Neuroendocrinol , vol.22 , Issue.7 , pp. 650-658
    • Campbell, R.E.1    Suter, K.J.2
  • 38
    • 67649831619 scopus 로고    scopus 로고
    • Dendro-dendritic bundling and shared synapses between gonadotropin-releasing hormone neurons
    • doi:10.1073/pnas.0903463106
    • Campbell RE, Gaidamaka G, Han SK, Herbison AE. Dendro-dendritic bundling and shared synapses between gonadotropin-releasing hormone neurons. Proc Natl Acad Sci U S A (2009) 106(26):10835-40. doi:10.1073/pnas.0903463106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.26 , pp. 10835-40
    • Campbell, R.E.1    Gaidamaka, G.2    Han, S.K.3    Herbison, A.E.4
  • 39
    • 80053163329 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone neurons extend complex highly branched dendritic trees outside the blood-brain barrier
    • doi:10.1210/en.2011-1228
    • Herde MK, Geist K, Campbell RE, Herbison AE. Gonadotropin-releasing hormone neurons extend complex highly branched dendritic trees outside the blood-brain barrier. Endocrinology (2011) 152(10):3832-41. doi:10.1210/en.2011-1228.
    • (2011) Endocrinology , vol.152 , Issue.10 , pp. 3832-3841
    • Herde, M.K.1    Geist, K.2    Campbell, R.E.3    Herbison, A.E.4
  • 40
    • 46349111652 scopus 로고    scopus 로고
    • Dendritic action potential initiation in hypothalamic gonadotropin-releasing hormone neurons
    • doi:10.1210/en.2008-0152
    • Roberts CB, Campbell RE, Herbison AE, Suter KJ. Dendritic action potential initiation in hypothalamic gonadotropin-releasing hormone neurons. Endocrinology (2008) 149(7):3355-60. doi:10.1210/en.2008-0152.
    • (2008) Endocrinology , vol.149 , Issue.7 , pp. 3355-3360
    • Roberts, C.B.1    Campbell, R.E.2    Herbison, A.E.3    Suter, K.J.4
  • 41
    • 0024601672 scopus 로고
    • Pulsatile gonadotropin-releasing hormone release from the human mediobasal hypothalamus in vitro:opiate receptor-mediated suppression
    • doi:10.1159/000125107
    • Rasmussen DD, Gambacciani M, Swartz W, Tueros VS, Yen SS. Pulsatile gonadotropin-releasing hormone release from the human mediobasal hypothalamus in vitro:opiate receptor-mediated suppression. Neuroendocrinology (1989) 49(2):150-6. doi:10.1159/000125107.
    • (1989) Neuroendocrinology , vol.49 , Issue.2 , pp. 150-156
    • Rasmussen, D.D.1    Gambacciani, M.2    Swartz, W.3    Tueros, V.S.4    Yen, S.S.5
  • 42
    • 70349342734 scopus 로고    scopus 로고
    • Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse
    • doi:10.1523/JNEUROSCI.1569-09.2009
    • Navarro VM, Gottsch ML, Chavkin C, Okamura H, Clifton DK, Steiner RA. Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse. J Neurosci (2009) 29(38):11859-66. doi:10.1523/JNEUROSCI.1569-09.2009.
    • (2009) J Neurosci , vol.29 , Issue.38 , pp. 11859-66
    • Navarro, V.M.1    Gottsch, M.L.2    Chavkin, C.3    Okamura, H.4    Clifton, D.K.5    Steiner, R.A.6
  • 43
    • 77649123886 scopus 로고    scopus 로고
    • Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat
    • doi:10.1523/JNEUROSCI.5848-09.2010
    • Wakabayashi Y, Nakada T, Murata K, Ohkura S, Mogi K, Navarro VM, et al. Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat. J Neurosci (2010) 30(8):3124-32. doi:10.1523/JNEUROSCI.5848-09.2010.
    • (2010) J Neurosci , vol.30 , Issue.8 , pp. 3124-3132
    • Wakabayashi, Y.1    Nakada, T.2    Murata, K.3    Ohkura, S.4    Mogi, K.5    Navarro, V.M.6
  • 44
    • 70349969812 scopus 로고    scopus 로고
    • Gonadotrophin-releasing hormone pulse generator activity in the hypothalamus of the goat
    • doi:10.1111/j.1365-2826.2009.01909.x
    • Ohkura S, Takase K, Matsuyama S, Mogi K, Ichimaru T, Wakabayashi Y, et al. Gonadotrophin-releasing hormone pulse generator activity in the hypothalamus of the goat. J Neuroendocrinol (2009) 21(10):813-21. doi:10.1111/j.1365-2826.2009.01909.x.
    • (2009) J Neuroendocrinol , vol.21 , Issue.10 , pp. 813-821
    • Ohkura, S.1    Takase, K.2    Matsuyama, S.3    Mogi, K.4    Ichimaru, T.5    Wakabayashi, Y.6
  • 45
    • 84886047999 scopus 로고    scopus 로고
    • Substance p immunoreactivity exhibits frequent colocalization with kisspeptin and neurokinin B in the human infundibular region
    • doi:10.1371/journal.pone.0072369
    • Hrabovszky E, Borsay BA, Racz K, Herczeg L, CiofiP, Bloom SR, et al. Substance p immunoreactivity exhibits frequent colocalization with kisspeptin and neurokinin B in the human infundibular region. PLoS ONE (2013) 8(8):e72369. doi:10.1371/journal.pone.0072369.
    • (2013) PLoS ONE , vol.8 , Issue.8
    • Hrabovszky, E.1    Borsay, B.A.2    Racz, K.3    Herczeg, L.4    Ciofi, P.5    Bloom, S.R.6
  • 46
    • 0021797722 scopus 로고
    • Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area
    • doi:10.1016/0196-9781(85)90050-6
    • Witkin JW, Silverman AJ. Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area. Peptides (1985) 6(2):263-71. doi:10.1016/0196-9781(85)90050-6.
    • (1985) Peptides , vol.6 , Issue.2 , pp. 263-271
    • Witkin, J.W.1    Silverman, A.J.2
  • 47
    • 0026003442 scopus 로고
    • Effects of gonadal steroids on the ultrastructure of GnRH neurons in the rhesus monkey:synaptic input and glial apposition
    • doi:10.1210/endo-129-2-1083
    • Witkin JW, Ferin M, Popilskis SJ, Silverman AJ. Effects of gonadal steroids on the ultrastructure of GnRH neurons in the rhesus monkey:synaptic input and glial apposition. Endocrinology (1991) 129(2):1083-92. doi:10.1210/endo-129-2-1083.
    • (1991) Endocrinology , vol.129 , Issue.2 , pp. 1083-1092
    • Witkin, J.W.1    Ferin, M.2    Popilskis, S.J.3    Silverman, A.J.4
  • 48
    • 0033305497 scopus 로고    scopus 로고
    • Estrogen receptor immunoreactivity is present in the majority of central histaminergic neurons:evidence for a new neuroendocrine pathway associated with luteinizing hormone-releasing hormone-synthesizing neurons in rats and humans
    • doi:10.1210/en.140.9.4335
    • Fekete CS, Strutton PH, Cagampang FR, Hrabovszky E, Kallo I, Shughrue PJ, et al. Estrogen receptor immunoreactivity is present in the majority of central histaminergic neurons:evidence for a new neuroendocrine pathway associated with luteinizing hormone-releasing hormone-synthesizing neurons in rats and humans. Endocrinology (1999) 140(9):4335-41. doi:10.1210/en.140.9.4335.
    • (1999) Endocrinology , vol.140 , Issue.9 , pp. 4335-4341
    • Fekete, C.S.1    Strutton, P.H.2    Cagampang, F.R.3    Hrabovszky, E.4    Kallo, I.5    Shughrue, P.J.6
  • 49
    • 84867760925 scopus 로고    scopus 로고
    • Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man
    • doi:10.1210/en.2012-1739
    • Molnar CS, Vida B, Sipos MT, CiofiP, Borsay BA, Racz K, et al. Morphological evidence for enhanced kisspeptin and neurokinin B signaling in the infundibular nucleus of the aging man. Endocrinology (2012) 153(11):5428-39. doi:10.1210/en.2012-1739.
    • (2012) Endocrinology , vol.153 , Issue.11 , pp. 5428-5439
    • Molnar, C.S.1    Vida, B.2    Sipos, M.T.3    Ciofi, P.4    Borsay, B.A.5    Racz, K.6
  • 50
    • 0036076434 scopus 로고    scopus 로고
    • Close juxtapositions between LHRH immunoreactive neurons and substance P immunoreactive axons in the human diencephalon
    • doi:10.1210/jc.2002-020996
    • Dudas B, Merchenthaler I. Close juxtapositions between LHRH immunoreactive neurons and substance P immunoreactive axons in the human diencephalon. J Clin Endocrinol Metab (2002) 87(6):2946-53. doi:10.1210/jc.2002-020996.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.6 , pp. 2946-2953
    • Dudas, B.1    Merchenthaler, I.2
  • 51
    • 84861316077 scopus 로고    scopus 로고
    • Glutamatergic and GABAergic innervation of human gonadotropin-releasing hormone-I neurons
    • doi:10.1210/en.2011-2106
    • Hrabovszky E, Molnar CS, Nagy R, Vida B, Borsay BA, Racz K, et al. Glutamatergic and GABAergic innervation of human gonadotropin-releasing hormone-I neurons. Endocrinology (2012) 153(6):2766-76. doi:10.1210/en.2011-2106.
    • (2012) Endocrinology , vol.153 , Issue.6 , pp. 2766-2776
    • Hrabovszky, E.1    Molnar, C.S.2    Nagy, R.3    Vida, B.4    Borsay, B.A.5    Racz, K.6
  • 52
    • 0036082812 scopus 로고    scopus 로고
    • Dendritic spine pathology:cause or consequence of neurological disorders?
    • doi:10.1016/S0165-0173(02)00158-3
    • Fiala JC, Spacek J, Harris KM. Dendritic spine pathology:cause or consequence of neurological disorders? Brain Res Brain Res Rev (2002) 39(1):29-54. doi:10.1016/S0165-0173(02)00158-3.
    • (2002) Brain Res Brain Res Rev , vol.39 , Issue.1 , pp. 29-54
    • Fiala, J.C.1    Spacek, J.2    Harris, K.M.3
  • 53
    • 33747399077 scopus 로고    scopus 로고
    • Sexual dimorphism in the organization of the rat hypothalamic infundibular area
    • doi:10.1016/j.neuroscience.2006.05.041
    • CiofiP, Leroy D, Tramu G. Sexual dimorphism in the organization of the rat hypothalamic infundibular area. Neuroscience (2006) 141(4):1731-45. doi:10.1016/j.neuroscience.2006.05.041.
    • (2006) Neuroscience , vol.141 , Issue.4 , pp. 1731-1745
    • Ciofi, P.1    Leroy, D.2    Tramu, G.3
  • 54
    • 0031737964 scopus 로고    scopus 로고
    • Evidence for terminal regulation of GnRH release by excitatory amino acids in the median eminence in female rats:a dual immunoelectron microscopic study
    • doi:10.1210/en.139.3.1458
    • Kawakami SI, Hirunagi K, Ichikawa M, Tsukamura H, Maeda KI. Evidence for terminal regulation of GnRH release by excitatory amino acids in the median eminence in female rats:a dual immunoelectron microscopic study. Endocrinology (1998) 139(3):1458-61. doi:10.1210/en.139.3.1458.
    • (1998) Endocrinology , vol.139 , Issue.3 , pp. 1458-1461
    • Kawakami, S.I.1    Hirunagi, K.2    Ichikawa, M.3    Tsukamura, H.4    Maeda, K.I.5
  • 55
    • 0037318546 scopus 로고    scopus 로고
    • Distribution of vesicular glutamate transporter-2 messenger ribonucleic Acid and protein in the septum-hypothalamus of the rat
    • doi:10.1210/en.2002-220908
    • Lin W, McKinney K, Liu L, Lakhlani S, Jennes L. Distribution of vesicular glutamate transporter-2 messenger ribonucleic Acid and protein in the septum-hypothalamus of the rat. Endocrinology (2003) 144(2):662-70. doi:10.1210/en.2002-220908.
    • (2003) Endocrinology , vol.144 , Issue.2 , pp. 662-670
    • Lin, W.1    McKinney, K.2    Liu, L.3    Lakhlani, S.4    Jennes, L.5
  • 56
    • 0032437602 scopus 로고    scopus 로고
    • Excitatory amino acids act on the median eminence nerve terminals to induce gonadotropin-releasing hormone release in female rats
    • doi:10.1006/gcen.1998.7140
    • Kawakami S, Ichikawa M, Murahashi K, Hirunagi K, Tsukamura H, Maeda K. Excitatory amino acids act on the median eminence nerve terminals to induce gonadotropin-releasing hormone release in female rats. Gen Comp Endocrinol (1998) 112(3):372-82. doi:10.1006/gcen.1998.7140.
    • (1998) Gen Comp Endocrinol , vol.112 , Issue.3 , pp. 372-382
    • Kawakami, S.1    Ichikawa, M.2    Murahashi, K.3    Hirunagi, K.4    Tsukamura, H.5    Maeda, K.6
  • 57
    • 22644439726 scopus 로고    scopus 로고
    • Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence
    • doi:10.1002/cne.20626
    • Krajewski SJ, Anderson MJ, Iles-Shih L, Chen KJ, Urbanski HF, Rance NE. Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence. J Comp Neurol (2005) 489(3):372-86. doi:10.1002/cne.20626.
    • (2005) J Comp Neurol , vol.489 , Issue.3 , pp. 372-386
    • Krajewski, S.J.1    Anderson, M.J.2    Iles-Shih, L.3    Chen, K.J.4    Urbanski, H.F.5    Rance, N.E.6
  • 58
    • 83655161318 scopus 로고    scopus 로고
    • Morphological evidence for direct interaction between kisspeptin and gonadotropin-releasing hormone neurons at the median eminence of the male goat:an immunoelectron microscopic study
    • doi:10.1159/000331576
    • Matsuyama S, Ohkura S, Mogi K, Wakabayashi Y, Mori Y, Tsukamura H, et al. Morphological evidence for direct interaction between kisspeptin and gonadotropin-releasing hormone neurons at the median eminence of the male goat:an immunoelectron microscopic study. Neuroendocrinology (2011) 94(4):323-32. doi:10.1159/000331576.
    • (2011) Neuroendocrinology , vol.94 , Issue.4 , pp. 323-332
    • Matsuyama, S.1    Ohkura, S.2    Mogi, K.3    Wakabayashi, Y.4    Mori, Y.5    Tsukamura, H.6
  • 59
    • 50449101532 scopus 로고    scopus 로고
    • Structural interactions between kisspeptin and GnRH neurons in the mediobasal hypothalamus of the male rhesus monkey (Macaca mulatta) as revealed by double immunofluorescence and confocal microscopy
    • doi:10.1210/en.2008-0438
    • Ramaswamy S, Guerriero KA, Gibbs RB, Plant TM. Structural interactions between kisspeptin and GnRH neurons in the mediobasal hypothalamus of the male rhesus monkey (Macaca mulatta) as revealed by double immunofluorescence and confocal microscopy. Endocrinology (2008) 149(9):4387-95. doi:10.1210/en.2008-0438.
    • (2008) Endocrinology , vol.149 , Issue.9 , pp. 4387-4395
    • Ramaswamy, S.1    Guerriero, K.A.2    Gibbs, R.B.3    Plant, T.M.4
  • 60
    • 77953203035 scopus 로고    scopus 로고
    • The kisspeptin system of the human hypothalamus:sexual dimorphism and relationship with gonadotropin-releasing hormone and neurokinin B neurons
    • doi:10.1111/j.1460-9568.2010.07239.x
    • Hrabovszky E, CiofiP, Vida B, Horvath MC, Keller E, Caraty A, et al. The kisspeptin system of the human hypothalamus:sexual dimorphism and relationship with gonadotropin-releasing hormone and neurokinin B neurons. Eur J Neurosci (2010) 31(11):1984-98. doi:10.1111/j.1460-9568.2010.07239.x.
    • (2010) Eur J Neurosci , vol.31 , Issue.11 , pp. 1984-1998
    • Hrabovszky, E.1    Ciofi, P.2    Vida, B.3    Horvath, M.C.4    Keller, E.5    Caraty, A.6
  • 61
    • 47949125934 scopus 로고    scopus 로고
    • Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals
    • doi:10.1210/en.2007-1487
    • d'Anglemont de Tassigny X, Fagg LA, Carlton MB, Colledge WH. Kisspeptin can stimulate gonadotropin-releasing hormone (GnRH) release by a direct action at GnRH nerve terminals. Endocrinology (2008) 149(8):3926-32. doi:10.1210/en.2007-1487.
    • (2008) Endocrinology , vol.149 , Issue.8 , pp. 3926-3932
    • d'Anglemont de Tassigny, X.1    Fagg, L.A.2    Carlton, M.B.3    Colledge, W.H.4
  • 62
    • 47949125690 scopus 로고    scopus 로고
    • An increase in kisspeptin-54 release occurs with the pubertal increase in luteinizing hormone-releasing hormone-1 release in the stalk-median eminence of female rhesus monkeys in vivo
    • doi:10.1210/en.2008-0231
    • Keen KL, Wegner FH, Bloom SR, Ghatei MA, Terasawa E. An increase in kisspeptin-54 release occurs with the pubertal increase in luteinizing hormone-releasing hormone-1 release in the stalk-median eminence of female rhesus monkeys in vivo. Endocrinology (2008) 149(8):4151-7. doi:10.1210/en.2008-0231.
    • (2008) Endocrinology , vol.149 , Issue.8 , pp. 4151-4157
    • Keen, K.L.1    Wegner, F.H.2    Bloom, S.R.3    Ghatei, M.A.4    Terasawa, E.5
  • 63
    • 2942750179 scopus 로고    scopus 로고
    • Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat
    • doi:10.1016/j.bbrc.2004.05.185
    • Matsui H, Takatsu Y, Kumano S, Matsumoto H, Ohtaki T. Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat. Biochem Biophys Res Commun (2004) 320(2):383-8. doi:10.1016/j.bbrc.2004.05.185.
    • (2004) Biochem Biophys Res Commun , vol.320 , Issue.2 , pp. 383-388
    • Matsui, H.1    Takatsu, Y.2    Kumano, S.3    Matsumoto, H.4    Ohtaki, T.5
  • 64
    • 20144372084 scopus 로고    scopus 로고
    • Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat
    • doi:10.1210/en.2004-1353
    • Navarro VM, Castellano JM, Fernandez-Fernandez R, Tovar S, Roa J, Mayen A, et al. Effects of KiSS-1 peptide, the natural ligand of GPR54, on follicle-stimulating hormone secretion in the rat. Endocrinology (2005) 146(4):1689-97. doi:10.1210/en.2004-1353.
    • (2005) Endocrinology , vol.146 , Issue.4 , pp. 1689-1697
    • Navarro, V.M.1    Castellano, J.M.2    Fernandez-Fernandez, R.3    Tovar, S.4    Roa, J.5    Mayen, A.6
  • 65
    • 13844317911 scopus 로고    scopus 로고
    • Increased hypothalamic GPR54 signaling:a potential mechanism for initiation of puberty in primates
    • doi:10.1073/pnas.0409822102
    • Shahab M, Mastronardi C, Seminara SB, Crowley WF, Ojeda SR, Plant TM. Increased hypothalamic GPR54 signaling:a potential mechanism for initiation of puberty in primates. Proc Natl Acad Sci U S A (2005) 102(6):2129-34. doi:10.1073/pnas.0409822102.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.6 , pp. 2129-2134
    • Shahab, M.1    Mastronardi, C.2    Seminara, S.B.3    Crowley, W.F.4    Ojeda, S.R.5    Plant, T.M.6
  • 66
  • 67
    • 35349022556 scopus 로고    scopus 로고
    • Kisspeptin-54 stimulates gonadotropin release most potently during the preovulatory phase of the menstrual cycle in women
    • doi:10.1210/jc.2007-1116
    • Dhillo WS, Chaudhri OB, Thompson EL, Murphy KG, Patterson M, Ramachandran R, et al. Kisspeptin-54 stimulates gonadotropin release most potently during the preovulatory phase of the menstrual cycle in women. J Clin Endocrinol Metab (2007) 92(10):3958-66. doi:10.1210/jc.2007-1116.
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.10 , pp. 3958-3966
    • Dhillo, W.S.1    Chaudhri, O.B.2    Thompson, E.L.3    Murphy, K.G.4    Patterson, M.5    Ramachandran, R.6
  • 68
    • 3342986342 scopus 로고    scopus 로고
    • Bi-directional associations between galanin and luteinizing hormone-releasing hormone neuronal systems in the human diencephalon
    • doi:10.1016/j.neuroscience.2004.05.018
    • Dudas B, Merchenthaler I. Bi-directional associations between galanin and luteinizing hormone-releasing hormone neuronal systems in the human diencephalon. Neuroscience (2004) 127(3):695-707. doi:10.1016/j.neuroscience.2004.05.018.
    • (2004) Neuroscience , vol.127 , Issue.3 , pp. 695-707
    • Dudas, B.1    Merchenthaler, I.2
  • 69
    • 0030474237 scopus 로고    scopus 로고
    • Expression of gamma-aminobutyric acid and gonadotropin-releasing hormone during neuronal migration through the olfactory system
    • doi:10.1210/en.137.12.5415
    • Tobet SA, Chickering TW, King JC, Stopa EG, Kim K, Kuo-Leblank V, et al. Expression of gamma-aminobutyric acid and gonadotropin-releasing hormone during neuronal migration through the olfactory system. Endocrinology (1996) 137(12):5415-20. doi:10.1210/en.137.12.5415.
    • (1996) Endocrinology , vol.137 , Issue.12 , pp. 5415-5420
    • Tobet, S.A.1    Chickering, T.W.2    King, J.C.3    Stopa, E.G.4    Kim, K.5    Kuo-Leblank, V.6
  • 70
    • 4344599091 scopus 로고    scopus 로고
    • Expression of vesicular glutamate transporter-2 in gonadotropin-releasing hormone neurons of the adult male rat
    • doi:10.1210/en.2004-0589
    • Hrabovszky E, Turi GF, Kallo I, Liposits Z. Expression of vesicular glutamate transporter-2 in gonadotropin-releasing hormone neurons of the adult male rat. Endocrinology (2004) 145(9):4018-21. doi:10.1210/en.2004-0589.
    • (2004) Endocrinology , vol.145 , Issue.9 , pp. 4018-4021
    • Hrabovszky, E.1    Turi, G.F.2    Kallo, I.3    Liposits, Z.4
  • 71
    • 0025032605 scopus 로고
    • Colocalization of galanin and luteinizing hormone-releasing hormone in a subset of preoptic hypothalamic neurons:anatomical and functional correlates
    • doi:10.1073/pnas.87.16.6326
    • Merchenthaler I, Lopez FJ, Negro-Vilar A. Colocalization of galanin and luteinizing hormone-releasing hormone in a subset of preoptic hypothalamic neurons:anatomical and functional correlates. Proc Natl Acad Sci U S A (1990) 87(16):6326-30. doi:10.1073/pnas.87.16.6326.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , Issue.16 , pp. 6326-6330
    • Merchenthaler, I.1    Lopez, F.J.2    Negro-Vilar, A.3
  • 72
    • 0025160996 scopus 로고
    • Coexistence of gonadotrophin-releasing hormone and galanin:immunohisto-chemical and functional studies
    • doi:10.1111/j.1365-2826.1990.tb00839.x
    • Coen CW, Montagnese C, Opacka-Juffry J. Coexistence of gonadotrophin-releasing hormone and galanin:immunohisto-chemical and functional studies. J Neuroendocrinol (1990) 2(2):107-11. doi:10.1111/j.1365-2826.1990.tb00839.x.
    • (1990) J Neuroendocrinol , vol.2 , Issue.2 , pp. 107-111
    • Coen, C.W.1    Montagnese, C.2    Opacka-Juffry, J.3
  • 73
    • 0033550887 scopus 로고    scopus 로고
    • Expression of galanin immunoreactivity in gonadotropin-releasing hormone neurons in mice:a confocal microscopic study
    • doi:10.1016/S0006-8993(99)01059-8
    • Rajendren G, Gibson MJ. Expression of galanin immunoreactivity in gonadotropin-releasing hormone neurons in mice:a confocal microscopic study. Brain Res (1999) 821(2):270-6. doi:10.1016/S0006-8993(99)01059-8.
    • (1999) Brain Res , vol.821 , Issue.2 , pp. 270-276
    • Rajendren, G.1    Gibson, M.J.2
  • 74
    • 0242468346 scopus 로고    scopus 로고
    • Immunoreactive galanin expression in ovine gonadotropin-releasing hormone neurones:no effects of gender or reproductive status
    • doi:10.1046/j.1365-2826.2003.01098.x
    • Dufourny L, Schofield N, Skinner DC. Immunoreactive galanin expression in ovine gonadotropin-releasing hormone neurones:no effects of gender or reproductive status. J Neuroendocrinol (2003) 15(11):1062-9. doi:10.1046/j.1365-2826.2003.01098.x.
    • (2003) J Neuroendocrinol , vol.15 , Issue.11 , pp. 1062-1069
    • Dufourny, L.1    Schofield, N.2    Skinner, D.C.3
  • 75
    • 0027482838 scopus 로고
    • Neonatal imprinting predetermines the sexually dimorphic, estrogen-dependent expression of galanin in luteinizing hormone-releasing hormone neurons
    • doi:10.1073/pnas.90.22.10479
    • Merchenthaler I, Lennard DE, Lopez FJ, Negro-Vilar A. Neonatal imprinting predetermines the sexually dimorphic, estrogen-dependent expression of galanin in luteinizing hormone-releasing hormone neurons. Proc Natl Acad Sci U S A (1993) 90(22):10479-83. doi:10.1073/pnas.90.22.10479.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , Issue.22 , pp. 10479-83
    • Merchenthaler, I.1    Lennard, D.E.2    Lopez, F.J.3    Negro-Vilar, A.4
  • 76
    • 0024525097 scopus 로고
    • Estrogen stimulates gonadotropin-releasing hormone release from rat hypothalamus independently through catecholamine and histamine in vitro
    • Ohtsuka S, Nishizaki T, Tasaka K, Miyake A, Tanizawa O, Yamatodani A, et al. Estrogen stimulates gonadotropin-releasing hormone release from rat hypothalamus independently through catecholamine and histamine in vitro. Acta Endocrinol (1989) 120(5):644-8.
    • (1989) Acta Endocrinol , vol.120 , Issue.5 , pp. 644-648
    • Ohtsuka, S.1    Nishizaki, T.2    Tasaka, K.3    Miyake, A.4    Tanizawa, O.5    Yamatodani, A.6
  • 77
    • 0034718199 scopus 로고    scopus 로고
    • Phenotypical segregation among female rat hypothalamic gonadotropin-releasing hormone neurons as revealed by the sexually dimorphic coexpression of cholecystokinin and neurotensin
    • doi:10.1016/S0306-4522(00)00186-X
    • CiofiP. Phenotypical segregation among female rat hypothalamic gonadotropin-releasing hormone neurons as revealed by the sexually dimorphic coexpression of cholecystokinin and neurotensin. Neuroscience (2000) 99(1):133-47. doi:10.1016/S0306-4522(00)00186-X.
    • (2000) Neuroscience , vol.99 , Issue.1 , pp. 133-147
    • Ciofi, P.1
  • 78
    • 0032460910 scopus 로고    scopus 로고
    • Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons
    • doi:10.1210/er.19.3.302
    • Herbison AE. Multimodal influence of estrogen upon gonadotropin-releasing hormone neurons. Endocr Rev (1998) 19(3):302-30. doi:10.1210/er.19.3.302.
    • (1998) Endocr Rev , vol.19 , Issue.3 , pp. 302-330
    • Herbison, A.E.1
  • 79
    • 0020580616 scopus 로고
    • Absence of oestradiol concentration in cell nuclei of LHRH-immunoreactive neurones
    • doi:10.1038/304345a0
    • Shivers BD, Harlan RE, Morrell JI, PfaffDW. Absence of oestradiol concentration in cell nuclei of LHRH-immunoreactive neurones. Nature (1983) 304(5924):345-7. doi:10.1038/304345a0.
    • (1983) Nature , vol.304 , Issue.5924 , pp. 345-347
    • Shivers, B.D.1    Harlan, R.E.2    Morrell, J.I.3    Pfaff, D.W.4
  • 80
    • 0026631473 scopus 로고
    • Further evidence that most luteinizing hormone-releasing hormone neurons are not directly estrogen-responsive:simultaneous localization of luteinizing hormone-releasing hormone and estrogen receptor immunoreactivity in the guinea-pig brain
    • doi:10.1111/j.1365-2826.1992.tb00173.x
    • Watson RE Jr, Langub MC Jr, Landis JW. Further evidence that most luteinizing hormone-releasing hormone neurons are not directly estrogen-responsive:simultaneous localization of luteinizing hormone-releasing hormone and estrogen receptor immunoreactivity in the guinea-pig brain. J Neuroendocrinol (1992) 4(3):311-7. doi:10.1111/j.1365-2826.1992.tb00173.x.
    • (1992) J Neuroendocrinol , vol.4 , Issue.3 , pp. 311-317
    • Watson Jr., R.E.1    Langub Jr., M.C.2    Landis, J.W.3
  • 81
    • 0026793061 scopus 로고
    • Localization of oestrogen receptors in preoptic neurons containing neurotensin but not tyrosine hydroxylase, cholecystokinin or luteinizing hormone-releasing hormone in the male and female rat
    • doi:10.1016/0306-4522(92)90423-Y
    • Herbison AE, Theodosis DT. Localization of oestrogen receptors in preoptic neurons containing neurotensin but not tyrosine hydroxylase, cholecystokinin or luteinizing hormone-releasing hormone in the male and female rat. Neuroscience (1992) 50(2):283-98. doi:10.1016/0306-4522(92)90423-Y.
    • (1992) Neuroscience , vol.50 , Issue.2 , pp. 283-298
    • Herbison, A.E.1    Theodosis, D.T.2
  • 82
  • 83
    • 0034456509 scopus 로고    scopus 로고
    • Detection of estrogen receptor-beta messenger ribonucleic acid and 125I-estrogen binding sites in luteinizing hormone-releasing hormone neurons of the rat brain
    • doi:10.1210/en.141.9.3506
    • Hrabovszky E, Shughrue PJ, Merchenthaler I, Hajszan T, Carpenter CD, Liposits Z, et al. Detection of estrogen receptor-beta messenger ribonucleic acid and 125I-estrogen binding sites in luteinizing hormone-releasing hormone neurons of the rat brain. Endocrinology (2000) 141(9):3506-9. doi:10.1210/en.141.9.3506.
    • (2000) Endocrinology , vol.141 , Issue.9 , pp. 3506-3509
    • Hrabovszky, E.1    Shughrue, P.J.2    Merchenthaler, I.3    Hajszan, T.4    Carpenter, C.D.5    Liposits, Z.6
  • 84
    • 0033303528 scopus 로고    scopus 로고
    • Detection of estrogen receptor alpha and beta messenger ribonucleic acids in adult gonadotropin-releasing hormone neurons
    • doi:10.1210/en.140.11.5195
    • Skynner MJ, Sim JA, Herbison AE. Detection of estrogen receptor alpha and beta messenger ribonucleic acids in adult gonadotropin-releasing hormone neurons. Endocrinology (1999) 140(11):5195-201. doi:10.1210/en.140.11.5195.
    • (1999) Endocrinology , vol.140 , Issue.11 , pp. 5195-5201
    • Skynner, M.J.1    Sim, J.A.2    Herbison, A.E.3
  • 85
    • 0034990094 scopus 로고    scopus 로고
    • Estrogen receptor-beta immunoreactivity in luteinizing hormone-releasing hormone neurons of the rat brain
    • doi:10.1210/en.142.7.3261
    • Hrabovszky E, Steinhauser A, Barabas K, Shughrue PJ, Petersen SL, Merchenthaler I, et al. Estrogen receptor-beta immunoreactivity in luteinizing hormone-releasing hormone neurons of the rat brain. Endocrinology (2001) 142(7):3261-4. doi:10.1210/en.142.7.3261.
    • (2001) Endocrinology , vol.142 , Issue.7 , pp. 3261-3264
    • Hrabovszky, E.1    Steinhauser, A.2    Barabas, K.3    Shughrue, P.J.4    Petersen, S.L.5    Merchenthaler, I.6
  • 86
    • 0034827697 scopus 로고    scopus 로고
    • Oestrogen receptor beta-immunoreactivity in gonadotropin releasing hormone-expressing neurones:regulation by oestrogen
    • doi:10.1046/j.1365-2826.2001.00708.x
    • Kallo I, Butler JA, Barkovics-Kallo M, Goubillon ML, Coen CW. Oestrogen receptor beta-immunoreactivity in gonadotropin releasing hormone-expressing neurones:regulation by oestrogen. J Neuroendocrinol (2001) 13(9):741-8. doi:10.1046/j.1365-2826.2001.00708.x.
    • (2001) J Neuroendocrinol , vol.13 , Issue.9 , pp. 741-748
    • Kallo, I.1    Butler, J.A.2    Barkovics-Kallo, M.3    Goubillon, M.L.4    Coen, C.W.5
  • 87
    • 0034777246 scopus 로고    scopus 로고
    • New evidence for estrogen receptors in gonadotropin-releasing hormone neurons
    • doi:10.1006/frne.2001.0219
    • Herbison AE, Pape JR. New evidence for estrogen receptors in gonadotropin-releasing hormone neurons. Front Neuroendocrinol (2001) 22(4):292-308. doi:10.1006/frne.2001.0219.
    • (2001) Front Neuroendocrinol , vol.22 , Issue.4 , pp. 292-308
    • Herbison, A.E.1    Pape, J.R.2
  • 88
    • 14944349356 scopus 로고    scopus 로고
    • Oestrogen receptor beta-immunoreactive neurones in the ovine hypothalamus:distribution and colocalisation with gonadotropin-releasing hormone
    • doi:10.1111/j.1365-2826.2005.01271.x
    • Skinner DC, Dufourny L. Oestrogen receptor beta-immunoreactive neurones in the ovine hypothalamus:distribution and colocalisation with gonadotropin-releasing hormone. J Neuroendocrinol (2005) 17(1):29-39. doi:10.1111/j.1365-2826.2005.01271.x.
    • (2005) J Neuroendocrinol , vol.17 , Issue.1 , pp. 29-39
    • Skinner, D.C.1    Dufourny, L.2
  • 89
    • 0027181143 scopus 로고
    • Distribution of estrogen receptor-immunoreactive cells in the preoptic area of the ewe:co-localization with glutamic acid decarboxylase but not luteinizing hormone-releasing hormone
    • doi:10.1159/000126433
    • Herbison AE, Robinson JE, Skinner DC. Distribution of estrogen receptor-immunoreactive cells in the preoptic area of the ewe:co-localization with glutamic acid decarboxylase but not luteinizing hormone-releasing hormone. Neuroendocrinology (1993) 57(4):751-9. doi:10.1159/000126433.
    • (1993) Neuroendocrinology , vol.57 , Issue.4 , pp. 751-759
    • Herbison, A.E.1    Robinson, J.E.2    Skinner, D.C.3
  • 91
    • 84864387183 scopus 로고    scopus 로고
    • Estradiol acts directly and indirectly on multiple signaling pathways to phosphorylate cAMP-response element binding protein in GnRH neurons
    • doi:10.1210/en.2012-1232
    • Cheong RY, Kwakowsky A, Barad Z, Porteous R, Herbison AE, Abraham IM. Estradiol acts directly and indirectly on multiple signaling pathways to phosphorylate cAMP-response element binding protein in GnRH neurons. Endocrinology (2012) 153(8):3792-803. doi:10.1210/en.2012-1232.
    • (2012) Endocrinology , vol.153 , Issue.8 , pp. 3792-3803
    • Cheong, R.Y.1    Kwakowsky, A.2    Barad, Z.3    Porteous, R.4    Herbison, A.E.5    Abraham, I.M.6
  • 92
    • 0038045425 scopus 로고    scopus 로고
    • Estrogen receptor beta mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo
    • Abraham IM, Han SK, Todman MG, Korach KS, Herbison AE. Estrogen receptor beta mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo. J Neurosci (2003) 23(13):5771-7.
    • (2003) J Neurosci , vol.23 , Issue.13 , pp. 5771-5777
    • Abraham, I.M.1    Han, S.K.2    Todman, M.G.3    Korach, K.S.4    Herbison, A.E.5
  • 93
    • 3242709480 scopus 로고    scopus 로고
    • Direct action of estradiol on gonadotropin-releasing hormone-1 neuronal activity via a transcription-dependent mechanism
    • doi:10.1523/JNEUROSCI.1006-04.2004
    • Temple JL, Laing E, Sunder A, Wray S. Direct action of estradiol on gonadotropin-releasing hormone-1 neuronal activity via a transcription-dependent mechanism. J Neurosci (2004) 24(28):6326-33. doi:10.1523/JNEUROSCI.1006-04.2004.
    • (2004) J Neurosci , vol.24 , Issue.28 , pp. 6326-6333
    • Temple, J.L.1    Laing, E.2    Sunder, A.3    Wray, S.4
  • 94
    • 33645514445 scopus 로고    scopus 로고
    • Ligand-independent effects of estrogen receptor beta on mouse gonadotropin-releasing hormone promoter activity
    • doi:10.1210/en.2005-1297
    • Pak TR, Chung WC, Roberts JL, Handa RJ. Ligand-independent effects of estrogen receptor beta on mouse gonadotropin-releasing hormone promoter activity. Endocrinology (2006) 147(4):1924-31. doi:10.1210/en.2005-1297.
    • (2006) Endocrinology , vol.147 , Issue.4 , pp. 1924-1931
    • Pak, T.R.1    Chung, W.C.2    Roberts, J.L.3    Handa, R.J.4
  • 95
    • 18844375856 scopus 로고    scopus 로고
    • Estrogen and estrogen receptor-{beta} (ER{beta})-selective ligands induce galanin expression within gonadotropin hormone-releasing hormone-immunoreactive neurons in the female rat brain
    • doi:10.1210/en.2004-1562
    • Merchenthaler I, Hoffman GE, Lane MV. Estrogen and estrogen receptor-{beta} (ER{beta})-selective ligands induce galanin expression within gonadotropin hormone-releasing hormone-immunoreactive neurons in the female rat brain. Endocrinology (2005) 146(6):2760-5. doi:10.1210/en.2004-1562.
    • (2005) Endocrinology , vol.146 , Issue.6 , pp. 2760-2765
    • Merchenthaler, I.1    Hoffman, G.E.2    Lane, M.V.3
  • 96
    • 54349112353 scopus 로고    scopus 로고
    • Classical estrogen receptor alpha signaling mediates negative and positive feedback on gonadotropin-releasing hormone neuron firing
    • doi:10.1210/en.2008-0520
    • Christian CA, Glidewell-Kenney C, Jameson JL, Moenter SM. Classical estrogen receptor alpha signaling mediates negative and positive feedback on gonadotropin-releasing hormone neuron firing. Endocrinology (2008) 149(11):5328-34. doi:10.1210/en.2008-0520.
    • (2008) Endocrinology , vol.149 , Issue.11 , pp. 5328-5334
    • Christian, C.A.1    Glidewell-Kenney, C.2    Jameson, J.L.3    Moenter, S.M.4
  • 97
    • 84880310849 scopus 로고    scopus 로고
    • Delayed puberty and estrogen resistance in a woman with estrogen receptor alpha variant
    • doi:10.1056/NEJMoa1303611
    • Quaynor SD, Stradtman EW Jr, Kim HG, Shen Y, Chorich LP, Schreihofer DA, et al. Delayed puberty and estrogen resistance in a woman with estrogen receptor alpha variant. N Engl J Med (2013) 369(2):164-71. doi:10.1056/NEJMoa1303611.
    • (2013) N Engl J Med , vol.369 , Issue.2 , pp. 164-171
    • Quaynor, S.D.1    Stradtman Jr., E.W.2    Kim, H.G.3    Shen, Y.4    Chorich, L.P.5    Schreihofer, D.A.6
  • 98
    • 0025852281 scopus 로고
    • Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women
    • doi:10.1210/endo-128-5-2239
    • Rance NE, Young WS III. Hypertrophy and increased gene expression of neurons containing neurokinin-B and substance-P messenger ribonucleic acids in the hypothalami of postmenopausal women. Endocrinology (1991) 128(5):2239-47. doi:10.1210/endo-128-5-2239.
    • (1991) Endocrinology , vol.128 , Issue.5 , pp. 2239-2247
    • Rance, N.E.1    Young I.I.I, W.S.2
  • 99
    • 34447115135 scopus 로고    scopus 로고
    • Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys
    • doi:10.1210/jc.2007-0553
    • Rometo AM, Krajewski SJ, Voytko ML, Rance NE. Hypertrophy and increased kisspeptin gene expression in the hypothalamic infundibular nucleus of postmenopausal women and ovariectomized monkeys. J Clin Endocrinol Metab (2007) 92(7):2744-50. doi:10.1210/jc.2007-0553.
    • (2007) J Clin Endocrinol Metab , vol.92 , Issue.7 , pp. 2744-2750
    • Rometo, A.M.1    Krajewski, S.J.2    Voytko, M.L.3    Rance, N.E.4
  • 100
    • 56649096022 scopus 로고    scopus 로고
    • Changes in prodynorphin gene expression and neuronal morphology in the hypothalamus of postmenopausal women
    • doi:10.1111/j.1365-2826.2008.01796.x
    • Rometo AM, Rance NE. Changes in prodynorphin gene expression and neuronal morphology in the hypothalamus of postmenopausal women. J Neuroendocrinol (2008) 20(12):1376-81. doi:10.1111/j.1365-2826.2008.01796.x.
    • (2008) J Neuroendocrinol , vol.20 , Issue.12 , pp. 1376-1381
    • Rometo, A.M.1    Rance, N.E.2
  • 101
    • 84857430001 scopus 로고    scopus 로고
    • Sexual dimorphism of kisspeptin and neurokinin B immunoreactive neurons in the infundibular nucleus of aged men and women
    • doi:10.3389/fendo.2011.00080
    • Hrabovszky E, Molnar CS, Sipos MT, Vida B, CiofiP, Borsay BA, et al. Sexual dimorphism of kisspeptin and neurokinin B immunoreactive neurons in the infundibular nucleus of aged men and women. Front Endocrinol (Lausanne) (2011) 2:80. doi:10.3389/fendo.2011.00080.
    • (2011) Front Endocrinol (Lausanne) , vol.2 , pp. 80
    • Hrabovszky, E.1    Molnar, C.S.2    Sipos, M.T.3    Vida, B.4    Ciofi, P.5    Borsay, B.A.6
  • 102
    • 84861303041 scopus 로고    scopus 로고
    • Arcuate kisspeptin/neurokinin B/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight
    • doi:10.1210/en.2012-1045
    • Mittelman-Smith MA, Williams H, Krajewski-Hall SJ, Lai J, CiofiP, McMullen NT, et al. Arcuate kisspeptin/neurokinin B/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight. Endocrinology (2012) 153(6):2800-12. doi:10.1210/en.2012-1045.
    • (2012) Endocrinology , vol.153 , Issue.6 , pp. 2800-2812
    • Mittelman-Smith, M.A.1    Williams, H.2    Krajewski-Hall, S.J.3    Lai, J.4    Ciofi, P.5    McMullen, N.T.6
  • 103
    • 84870387339 scopus 로고    scopus 로고
    • Role for kisspeptin/neurokinin B/dynorphin (KNDy) neurons in cutaneous vasodilatation and the estrogen modulation of body temperature
    • doi:10.1073/pnas.1211517109
    • Mittelman-Smith MA, Williams H, Krajewski-Hall SJ, McMullen NT, Rance NE. Role for kisspeptin/neurokinin B/dynorphin (KNDy) neurons in cutaneous vasodilatation and the estrogen modulation of body temperature. Proc Natl Acad Sci U S A (2012) 109(48):19846-51. doi:10.1073/pnas.1211517109.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.48 , pp. 19846-51
    • Mittelman-Smith, M.A.1    Williams, H.2    Krajewski-Hall, S.J.3    McMullen, N.T.4    Rance, N.E.5
  • 105
    • 0016722038 scopus 로고
    • Surgical disconnection of the medial basal hypothalamus and pituitary function in the rhesus monkey. I. Gonadotropin secretion
    • doi:10.1210/endo-96-5-1088
    • Krey LC, Butler WR, Knobil E. Surgical disconnection of the medial basal hypothalamus and pituitary function in the rhesus monkey. I. Gonadotropin secretion. Endocrinology (1975) 96(5):1073-87. doi:10.1210/endo-96-5-1088.
    • (1975) Endocrinology , vol.96 , Issue.5 , pp. 1073-1087
    • Krey, L.C.1    Butler, W.R.2    Knobil, E.3
  • 106
    • 0017720258 scopus 로고
    • Estrogen-induced gonadotropin surges in decerebrated female rhesus monkeys with medial basal hypothalamic peninsulae
    • doi:10.1210/endo-101-4-1264
    • Hess DL, Wilkins RH, Moossy J, Chang JL, Plant TM, McCormack JT, et al. Estrogen-induced gonadotropin surges in decerebrated female rhesus monkeys with medial basal hypothalamic peninsulae. Endocrinology (1977) 101(4):1264-71. doi:10.1210/endo-101-4-1264.
    • (1977) Endocrinology , vol.101 , Issue.4 , pp. 1264-1271
    • Hess, D.L.1    Wilkins, R.H.2    Moossy, J.3    Chang, J.L.4    Plant, T.M.5    McCormack, J.T.6
  • 107
    • 0018848036 scopus 로고
    • The neuroendocrine control of the menstrual cycle
    • Knobil E. The neuroendocrine control of the menstrual cycle. Recent Prog Horm Res (1980) 36:53-88.
    • (1980) Recent Prog Horm Res , vol.36 , pp. 53-88
    • Knobil, E.1
  • 108
    • 0025855191 scopus 로고
    • Neuropeptide Y modulates the binding of a gonadotropin-releasing hormone (GnRH) analog to anterior pituitary GnRH receptor sites
    • doi:10.1210/endo-128-5-2309
    • Parker SL, Kalra SP, Crowley WR. Neuropeptide Y modulates the binding of a gonadotropin-releasing hormone (GnRH) analog to anterior pituitary GnRH receptor sites. Endocrinology (1991) 128(5):2309-16. doi:10.1210/endo-128-5-2309.
    • (1991) Endocrinology , vol.128 , Issue.5 , pp. 2309-2316
    • Parker, S.L.1    Kalra, S.P.2    Crowley, W.R.3
  • 109
    • 0023190367 scopus 로고
    • Neuropeptide Y stimulates the release of luteinizing hormone-releasing hormone from medial basal hypothalamus in vitro:modulation by ovarian hormones
    • doi:10.1159/000124804
    • Crowley WR, Kalra SP. Neuropeptide Y stimulates the release of luteinizing hormone-releasing hormone from medial basal hypothalamus in vitro:modulation by ovarian hormones. Neuroendocrinology (1987) 46(2):97-103. doi:10.1159/000124804.
    • (1987) Neuroendocrinology , vol.46 , Issue.2 , pp. 97-103
    • Crowley, W.R.1    Kalra, S.P.2
  • 110
    • 0026016708 scopus 로고
    • Infusion of neuropeptide Y into the stalk-median eminence stimulates in vivo release of luteinizing hormone-release hormone in gonadectomized rhesus monkeys
    • doi:10.1210/endo-128-2-1144
    • Woller MJ, Terasawa E. Infusion of neuropeptide Y into the stalk-median eminence stimulates in vivo release of luteinizing hormone-release hormone in gonadectomized rhesus monkeys. Endocrinology (1991) 128(2):1144-50. doi:10.1210/endo-128-2-1144.
    • (1991) Endocrinology , vol.128 , Issue.2 , pp. 1144-1150
    • Woller, M.J.1    Terasawa, E.2
  • 111
    • 0025037635 scopus 로고
    • Morphological evidence for neuronal regulation of luteinizing hormone-releasing hormone-containing neurons by neuropeptide Y in the rat septo-preoptic area
    • doi:10.1016/0304-3940(90)90857-6
    • Tsuruo Y, Kawano H, Kagotani Y, Hisano S, Daikoku S, Chihara K, et al. Morphological evidence for neuronal regulation of luteinizing hormone-releasing hormone-containing neurons by neuropeptide Y in the rat septo-preoptic area. Neurosci Lett (1990) 110(3):261-6. doi:10.1016/0304-3940(90)90857-6.
    • (1990) Neurosci Lett , vol.110 , Issue.3 , pp. 261-266
    • Tsuruo, Y.1    Kawano, H.2    Kagotani, Y.3    Hisano, S.4    Daikoku, S.5    Chihara, K.6
  • 112
    • 0033303823 scopus 로고    scopus 로고
    • Morphological evidence for direct interaction between arcuate nucleus neuropeptide Y (NPY) neurons and gonadotropin-releasing hormone neurons and the possible involvement of NPY Y1 receptors
    • doi:10.1210/en.140.11.5382
    • Li C, Chen P, Smith MS. Morphological evidence for direct interaction between arcuate nucleus neuropeptide Y (NPY) neurons and gonadotropin-releasing hormone neurons and the possible involvement of NPY Y1 receptors. Endocrinology (1999) 140(11):5382-90. doi:10.1210/en.140.11.5382.
    • (1999) Endocrinology , vol.140 , Issue.11 , pp. 5382-5390
    • Li, C.1    Chen, P.2    Smith, M.S.3
  • 113
    • 0034909815 scopus 로고    scopus 로고
    • Hypothalamic circuitry of neuropeptide Y regulation of neuroendocrine function and food intake via the Y5 receptor subtype
    • doi:10.1159/000054676
    • Campbell RE, Ffrench-Mullen JM, Cowley MA, Smith MS, Grove KL. Hypothalamic circuitry of neuropeptide Y regulation of neuroendocrine function and food intake via the Y5 receptor subtype. Neuroendocrinology (2001) 74(2):106-19. doi:10.1159/000054676.
    • (2001) Neuroendocrinology , vol.74 , Issue.2 , pp. 106-119
    • Campbell, R.E.1    Ffrench-Mullen, J.M.2    Cowley, M.A.3    Smith, M.S.4    Grove, K.L.5
  • 114
    • 0033598168 scopus 로고    scopus 로고
    • Identification and characterization of estrogen receptor alpha-containing neurons projecting to the vicinity of the gonadotropin-releasing hormone perikarya in the rostral preoptic area of the rat
    • doi:10.1002/(SICI)1096-9861(19990823)411:2<346::AID-CNE13>3.0.CO;2-S
    • Simonian SX, Spratt DP, Herbison AE. Identification and characterization of estrogen receptor alpha-containing neurons projecting to the vicinity of the gonadotropin-releasing hormone perikarya in the rostral preoptic area of the rat. J Comp Neurol (1999) 411(2):346-58. doi:10.1002/(SICI)1096-9861(19990823)411:2<346::AID-CNE13>3.0.CO;2-S.
    • (1999) J Comp Neurol , vol.411 , Issue.2 , pp. 346-358
    • Simonian, S.X.1    Spratt, D.P.2    Herbison, A.E.3
  • 115
    • 0242468477 scopus 로고    scopus 로고
    • Origin of neuropeptide Y-containing afferents to gonadotropin-releasing hormone neurons in male mice
    • doi:10.1210/en.2003-0470
    • Turi GF, Liposits Z, Moenter SM, Fekete C, Hrabovszky E. Origin of neuropeptide Y-containing afferents to gonadotropin-releasing hormone neurons in male mice. Endocrinology (2003) 144(11):4967-74. doi:10.1210/en.2003-0470.
    • (2003) Endocrinology , vol.144 , Issue.11 , pp. 4967-4974
    • Turi, G.F.1    Liposits, Z.2    Moenter, S.M.3    Fekete, C.4    Hrabovszky, E.5
  • 116
    • 0032443807 scopus 로고    scopus 로고
    • The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice
    • doi:10.1073/pnas.95.25.15043
    • Broberger C, Johansen J, Johansson C, Schalling M, Hokfelt T. The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proc Natl Acad Sci U S A (1998) 95(25):15043-8. doi:10.1073/pnas.95.25.15043.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , Issue.25 , pp. 15043-8
    • Broberger, C.1    Johansen, J.2    Johansson, C.3    Schalling, M.4    Hokfelt, T.5
  • 117
    • 84950170753 scopus 로고
    • Colocalization of neuropeptide Y immunoreactivity in brainstem catecholaminergic neurons that project to the paraventricular nucleus of the hypothalamus
    • doi:10.1002/cne.902410203
    • Sawchenko PE, Swanson LW, Grzanna R, Howe PR, Bloom SR, Polak JM. Colocalization of neuropeptide Y immunoreactivity in brainstem catecholaminergic neurons that project to the paraventricular nucleus of the hypothalamus. J Comp Neurol (1985) 241(2):138-53. doi:10.1002/cne.902410203.
    • (1985) J Comp Neurol , vol.241 , Issue.2 , pp. 138-153
    • Sawchenko, P.E.1    Swanson, L.W.2    Grzanna, R.3    Howe, P.R.4    Bloom, S.R.5    Polak, J.M.6
  • 118
    • 84859938555 scopus 로고    scopus 로고
    • Balancing ovulation and anovulation:integration of the reproductive and energy balance axes by neuropeptides
    • doi:10.1093/humupd/dms004
    • Evans JJ, Anderson GM. Balancing ovulation and anovulation:integration of the reproductive and energy balance axes by neuropeptides. Hum Reprod Update (2012) 18(3):313-32. doi:10.1093/humupd/dms004.
    • (2012) Hum Reprod Update , vol.18 , Issue.3 , pp. 313-332
    • Evans, J.J.1    Anderson, G.M.2
  • 119
    • 0035924078 scopus 로고    scopus 로고
    • Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism
    • doi:10.1016/S0303-7207(01)00620-7
    • Raposinho PD, Pierroz DD, Broqua P, White RB, Pedrazzini T, Aubert ML. Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism. Mol Cell Endocrinol (2001) 185(1-2):195-204. doi:10.1016/S0303-7207(01)00620-7.
    • (2001) Mol Cell Endocrinol , vol.185 , Issue.1-2 , pp. 195-204
    • Raposinho, P.D.1    Pierroz, D.D.2    Broqua, P.3    White, R.B.4    Pedrazzini, T.5    Aubert, M.L.6
  • 120
    • 0028925181 scopus 로고
    • Chronic administration of neuropeptide Y into the lateral ventricle starting at 30 days of life delays sexual maturation in the female rat
    • doi:10.1159/000126851
    • Pierroz DD, Gruaz NM, d'Alieves V, Aubert ML. Chronic administration of neuropeptide Y into the lateral ventricle starting at 30 days of life delays sexual maturation in the female rat. Neuroendocrinology (1995) 61(3):293-300. doi:10.1159/000126851.
    • (1995) Neuroendocrinology , vol.61 , Issue.3 , pp. 293-300
    • Pierroz, D.D.1    Gruaz, N.M.2    d'Alieves, V.3    Aubert, M.L.4
  • 121
    • 0027475201 scopus 로고
    • Neuropeptide Y administered chronically into the lateral ventricle profoundly inhibits both the gonadotropic and the somatotropic axis in intact adult female rats
    • doi:10.1210/en.132.1.224
    • Catzeflis C, Pierroz DD, Rohner-Jeanrenaud F, Rivier JE, Sizonenko PC, Aubert ML. Neuropeptide Y administered chronically into the lateral ventricle profoundly inhibits both the gonadotropic and the somatotropic axis in intact adult female rats. Endocrinology (1993) 132(1):224-34. doi:10.1210/en.132.1.224.
    • (1993) Endocrinology , vol.132 , Issue.1 , pp. 224-234
    • Catzeflis, C.1    Pierroz, D.D.2    Rohner-Jeanrenaud, F.3    Rivier, J.E.4    Sizonenko, P.C.5    Aubert, M.L.6
  • 122
    • 0022381444 scopus 로고
    • Effects of neuropeptide Y (NPY) on the release of anterior pituitary hormones in the rat
    • doi:10.1016/0196-9781(85)90451-6
    • Kerkerian L, Guy J, Lefevre G, Pelletier G. Effects of neuropeptide Y (NPY) on the release of anterior pituitary hormones in the rat. Peptides (1985) 6(6):1201-4. doi:10.1016/0196-9781(85)90451-6.
    • (1985) Peptides , vol.6 , Issue.6 , pp. 1201-1204
    • Kerkerian, L.1    Guy, J.2    Lefevre, G.3    Pelletier, G.4
  • 123
    • 0024994253 scopus 로고
    • Third-ventricular infusion of neuropeptide Y suppresses luteinizing hormone secretion in ovariectomized rhesus macaques
    • doi:10.1210/endo-127-5-2437
    • Kaynard AH, Pau KY, Hess DL, Spies HG. Third-ventricular infusion of neuropeptide Y suppresses luteinizing hormone secretion in ovariectomized rhesus macaques. Endocrinology (1990) 127(5):2437-44. doi:10.1210/endo-127-5-2437.
    • (1990) Endocrinology , vol.127 , Issue.5 , pp. 2437-2444
    • Kaynard, A.H.1    Pau, K.Y.2    Hess, D.L.3    Spies, H.G.4
  • 124
    • 0023405202 scopus 로고
    • Effects of neuropeptide Y, NPY analog (norleucine4-NPY), galanin and neuropeptide K on LH release in ovariectomized (ovx) and ovx estrogen, progesterone-treated rats
    • doi:10.1016/0196-9781(87)90081-7
    • Sahu A, Crowley WR, Tatemoto K, Balasubramaniam A, Kalra SP. Effects of neuropeptide Y, NPY analog (norleucine4-NPY), galanin and neuropeptide K on LH release in ovariectomized (ovx) and ovx estrogen, progesterone-treated rats. Peptides (1987) 8(5):921-6. doi:10.1016/0196-9781(87)90081-7.
    • (1987) Peptides , vol.8 , Issue.5 , pp. 921-926
    • Sahu, A.1    Crowley, W.R.2    Tatemoto, K.3    Balasubramaniam, A.4    Kalra, S.P.5
  • 125
    • 0347914570 scopus 로고    scopus 로고
    • Tachykinins and tachykinin receptors:a growing family
    • doi:10.1016/j.lfs.2003.09.039
    • Pennefather JN, Lecci A, Candenas ML, Patak E, Pinto FM, Maggi CA. Tachykinins and tachykinin receptors:a growing family. Life Sci (2004) 74(12):1445-63. doi:10.1016/j.lfs.2003.09.039.
    • (2004) Life Sci , vol.74 , Issue.12 , pp. 1445-1463
    • Pennefather, J.N.1    Lecci, A.2    Candenas, M.L.3    Patak, E.4    Pinto, F.M.5    Maggi, C.A.6
  • 126
    • 80052726039 scopus 로고    scopus 로고
    • Tachykinins and the hypothalamo-pituitary-gonadal axis:an update
    • doi:10.1016/j.peptides.2011.07.009
    • Lasaga M, Debeljuk L. Tachykinins and the hypothalamo-pituitary-gonadal axis:an update. Peptides (2011) 32(9):1972-8. doi:10.1016/j.peptides.2011.07.009.
    • (2011) Peptides , vol.32 , Issue.9 , pp. 1972-1978
    • Lasaga, M.1    Debeljuk, L.2
  • 127
    • 0024422152 scopus 로고
    • Substance P receptors in human pituitary:a potential inhibitor of luteinizing hormone secretion
    • doi:10.1210/jcem-69-3-612
    • Wormald PJ, Millar RP, Kerdelhue B. Substance P receptors in human pituitary:a potential inhibitor of luteinizing hormone secretion. J Clin Endocrinol Metab (1989) 69(3):612-5. doi:10.1210/jcem-69-3-612.
    • (1989) J Clin Endocrinol Metab , vol.69 , Issue.3 , pp. 612-615
    • Wormald, P.J.1    Millar, R.P.2    Kerdelhue, B.3
  • 128
    • 0025306320 scopus 로고
    • Stimulatory role of substance P on gonadotropin release in ovariectomized rats
    • doi:10.1159/000125386
    • Arisawa M, De Palatis L, Ho R, Snyder GD, Yu WH, Pan G, et al. Stimulatory role of substance P on gonadotropin release in ovariectomized rats. Neuroendocrinology (1990) 51(5):523-9. doi:10.1159/000125386.
    • (1990) Neuroendocrinology , vol.51 , Issue.5 , pp. 523-529
    • Arisawa, M.1    De Palatis, L.2    Ho, R.3    Snyder, G.D.4    Yu, W.H.5    Pan, G.6
  • 129
    • 0021277958 scopus 로고
    • Hypothalamic substance P-containing neurons. Sex-dependent topographical differences and ultrastructural transformations associated with stages of the estrous cycle
    • doi:10.1016/0006-8993(84)90439-6
    • Tsuruo Y, Hisano S, Okamura Y, Tsukamoto N, Daikoku S. Hypothalamic substance P-containing neurons. Sex-dependent topographical differences and ultrastructural transformations associated with stages of the estrous cycle. Brain Res (1984) 305(2):331-41. doi:10.1016/0006-8993(84)90439-6.
    • (1984) Brain Res , vol.305 , Issue.2 , pp. 331-341
    • Tsuruo, Y.1    Hisano, S.2    Okamura, Y.3    Tsukamoto, N.4    Daikoku, S.5
  • 130
    • 0023105101 scopus 로고
    • Immunohistochemical studies on the roles of substance P in the rat hypothalamus:possible implication in the hypothalamic-hypophysial-gonadal axis
    • doi:10.1159/000124764
    • Tsuruo Y, Hisano S, Nakanishi J, Katoh S, Daikoku S. Immunohistochemical studies on the roles of substance P in the rat hypothalamus:possible implication in the hypothalamic-hypophysial-gonadal axis. Neuroendocrinology (1987) 45(5):389-401. doi:10.1159/000124764.
    • (1987) Neuroendocrinology , vol.45 , Issue.5 , pp. 389-401
    • Tsuruo, Y.1    Hisano, S.2    Nakanishi, J.3    Katoh, S.4    Daikoku, S.5
  • 131
    • 0026031147 scopus 로고
    • Substance P-containing neurons innervating LHRH-containing neurons in the septo-preoptic area of rats
    • doi:10.1159/000125724
    • Tsuruo Y, Kawano H, Hisano S, Kagotani Y, Daikoku S, Zhang T, et al. Substance P-containing neurons innervating LHRH-containing neurons in the septo-preoptic area of rats. Neuroendocrinology (1991) 53(3):236-45. doi:10.1159/000125724.
    • (1991) Neuroendocrinology , vol.53 , Issue.3 , pp. 236-245
    • Tsuruo, Y.1    Kawano, H.2    Hisano, S.3    Kagotani, Y.4    Daikoku, S.5    Zhang, T.6
  • 132
    • 0017862993 scopus 로고
    • Dense plexus of substance P immunoreactive nerve terminals in eminentia medialis of the primate hypothalamus
    • doi:10.1073/pnas.75.2.1013
    • Hokfelt T, Pernow B, Nilsson G, Wetterberg L, Goldstein M, Jeffcoate SL. Dense plexus of substance P immunoreactive nerve terminals in eminentia medialis of the primate hypothalamus. Proc Natl Acad Sci U S A (1978) 75(2):1013-5. doi:10.1073/pnas.75.2.1013.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , Issue.2 , pp. 1013-1015
    • Hokfelt, T.1    Pernow, B.2    Nilsson, G.3    Wetterberg, L.4    Goldstein, M.5    Jeffcoate, S.L.6
  • 133
    • 33748470566 scopus 로고    scopus 로고
    • Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus:morphologic evidence of interrelated function within the arcuate nucleus
    • doi:10.1002/cne.21086
    • Burke MC, Letts PA, Krajewski SJ, Rance NE. Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus:morphologic evidence of interrelated function within the arcuate nucleus. J Comp Neurol (2006) 498(5):712-26. doi:10.1002/cne.21086.
    • (2006) J Comp Neurol , vol.498 , Issue.5 , pp. 712-726
    • Burke, M.C.1    Letts, P.A.2    Krajewski, S.J.3    Rance, N.E.4
  • 134
    • 80054942605 scopus 로고    scopus 로고
    • Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse
    • doi:10.1210/en.2011-1521
    • Gottsch ML, Popa SM, Lawhorn JK, Qiu J, Tonsfeldt KJ, Bosch MA, et al. Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology (2011) 152(11):4298-309. doi:10.1210/en.2011-1521.
    • (2011) Endocrinology , vol.152 , Issue.11 , pp. 4298-4309
    • Gottsch, M.L.1    Popa, S.M.2    Lawhorn, J.K.3    Qiu, J.4    Tonsfeldt, K.J.5    Bosch, M.A.6
  • 135
    • 0021040521 scopus 로고
    • Galanin-a novel biologically active peptide from porcine intestine
    • doi:10.1016/0014-5793(83)80033-7
    • Tatemoto K, Rokaeus A, Jornvall H, McDonald TJ, Mutt V. Galanin-a novel biologically active peptide from porcine intestine. FEBS Lett (1983) 164(1):124-8. doi:10.1016/0014-5793(83)80033-7.
    • (1983) FEBS Lett , vol.164 , Issue.1 , pp. 124-128
    • Tatemoto, K.1    Rokaeus, A.2    Jornvall, H.3    McDonald, T.J.4    Mutt, V.5
  • 136
    • 79952262062 scopus 로고    scopus 로고
    • Galanin:a multitalented neuropeptide
    • Hokfelt T, Tatemoto K. Galanin:a multitalented neuropeptide. EXS (2010) 102:1-5.
    • (2010) EXS , vol.102 , pp. 1-5
    • Hokfelt, T.1    Tatemoto, K.2
  • 137
    • 0344798036 scopus 로고
    • Galanin is an estrogen-inducible, secretory product of the rat anterior pituitary
    • doi:10.1073/pnas.85.19.7408
    • Kaplan LM, Gabriel SM, Koenig JI, Sunday ME, Spindel ER, Martin JB, et al. Galanin is an estrogen-inducible, secretory product of the rat anterior pituitary. Proc Natl Acad Sci U S A (1988) 85(19):7408-12. doi:10.1073/pnas.85.19.7408.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , Issue.19 , pp. 7408-7412
    • Kaplan, L.M.1    Gabriel, S.M.2    Koenig, J.I.3    Sunday, M.E.4    Spindel, E.R.5    Martin, J.B.6
  • 138
    • 0025794284 scopus 로고
    • Galanin:a hypothalamic-hypophysiotropic hormone modulating reproductive functions
    • doi:10.1073/pnas.88.10.4508
    • Lopez FJ, Merchenthaler I, Ching M, Wisniewski MG, Negro-Vilar A. Galanin:a hypothalamic-hypophysiotropic hormone modulating reproductive functions. Proc Natl Acad Sci U S A (1991) 88(10):4508-12. doi:10.1073/pnas.88.10.4508.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , Issue.10 , pp. 4508-4512
    • Lopez, F.J.1    Merchenthaler, I.2    Ching, M.3    Wisniewski, M.G.4    Negro-Vilar, A.5
  • 139
    • 0028078584 scopus 로고
    • Role of galanin in stimulation of pituitary luteinizing hormone secretion as revealed by a specific receptor antagonist, galantide
    • doi:10.1210/en.134.2.529
    • Sahu A, Xu B, Kalra SP. Role of galanin in stimulation of pituitary luteinizing hormone secretion as revealed by a specific receptor antagonist, galantide. Endocrinology (1994) 134(2):529-36. doi:10.1210/en.134.2.529.
    • (1994) Endocrinology , vol.134 , Issue.2 , pp. 529-536
    • Sahu, A.1    Xu, B.2    Kalra, S.P.3
  • 140
    • 0025895499 scopus 로고
    • The hypophysiotropic galanin system of the rat brain
    • doi:10.1016/0306-4522(91)90084-2
    • Merchenthaler I. The hypophysiotropic galanin system of the rat brain. Neuroscience (1991) 44(3):643-54. doi:10.1016/0306-4522(91)90084-2.
    • (1991) Neuroscience , vol.44 , Issue.3 , pp. 643-654
    • Merchenthaler, I.1
  • 141
    • 0026005845 scopus 로고
    • Sexual differences in the distribution of neurons coexpressing galanin and luteinizing hormone-releasing hormone in the rat brain
    • doi:10.1210/endo-129-4-1977
    • Merchenthaler I, Lopez FJ, Lennard DE, Negro-Vilar A. Sexual differences in the distribution of neurons coexpressing galanin and luteinizing hormone-releasing hormone in the rat brain. Endocrinology (1991) 129(4):1977-86. doi:10.1210/endo-129-4-1977.
    • (1991) Endocrinology , vol.129 , Issue.4 , pp. 1977-1986
    • Merchenthaler, I.1    Lopez, F.J.2    Lennard, D.E.3    Negro-Vilar, A.4
  • 142
    • 0035955918 scopus 로고    scopus 로고
    • Galanin synaptic input to gonadotropin-releasing hormone perikarya in juvenile and adult female mice:implications for sexual maturity
    • doi:10.1016/S0165-3806(01)00257-7
    • Rajendren G, Li X. Galanin synaptic input to gonadotropin-releasing hormone perikarya in juvenile and adult female mice:implications for sexual maturity. Brain Res Dev Brain Res (2001) 131(1-2):161-5. doi:10.1016/S0165-3806(01)00257-7.
    • (2001) Brain Res Dev Brain Res , vol.131 , Issue.1-2 , pp. 161-165
    • Rajendren, G.1    Li, X.2
  • 143
    • 78649498604 scopus 로고    scopus 로고
    • Corticotrophin-releasing factor and stress-induced inhibition of the gonadotrophin-releasing hormone pulse generator in the female
    • doi:10.1016/j.brainres.2010.08.036
    • Li XF, Knox AM, O'Byrne KT. Corticotrophin-releasing factor and stress-induced inhibition of the gonadotrophin-releasing hormone pulse generator in the female. Brain Res (2010) 1364:153-63. doi:10.1016/j.brainres.2010.08.036.
    • (2010) Brain Res , vol.1364 , pp. 153-163
    • Li, X.F.1    Knox, A.M.2    O'Byrne, K.T.3
  • 144
    • 0025071807 scopus 로고
    • Corticotropin-releasing factor and gonadotropin-releasing hormone pulse generator activity in the rhesus monkey. Electrophysiological studies
    • doi:10.1159/000125563
    • Williams CL, Nishihara M, Thalabard JC, Grosser PM, Hotchkiss J, Knobil E. Corticotropin-releasing factor and gonadotropin-releasing hormone pulse generator activity in the rhesus monkey. Electrophysiological studies. Neuroendocrinology (1990) 52(2):133-7. doi:10.1159/000125563.
    • (1990) Neuroendocrinology , vol.52 , Issue.2 , pp. 133-137
    • Williams, C.L.1    Nishihara, M.2    Thalabard, J.C.3    Grosser, P.M.4    Hotchkiss, J.5    Knobil, E.6
  • 145
    • 3543003513 scopus 로고    scopus 로고
    • The influence of 17beta-oestradiol on corticotrophin-releasing hormone induced suppression of luteinising hormone pulses and the role of CRH in hypoglycaemic stress-induced suppression of pulsatile LH secretion in the female rat
    • doi:10.1080/1025389042000218988
    • Cates PS, Li XF, O'Byrne KT. The influence of 17beta-oestradiol on corticotrophin-releasing hormone induced suppression of luteinising hormone pulses and the role of CRH in hypoglycaemic stress-induced suppression of pulsatile LH secretion in the female rat. Stress (2004) 7(2):113-8. doi:10.1080/1025389042000218988.
    • (2004) Stress , vol.7 , Issue.2 , pp. 113-118
    • Cates, P.S.1    Li, X.F.2    O'Byrne, K.T.3
  • 146
    • 0023867745 scopus 로고
    • Immunocytochemical evidence for direct synaptic connections between corticotrophin-releasing factor (CRF) and gonadotrophin-releasing hormone (GnRH)-containing neurons in the preoptic area of the rat
    • doi:10.1016/0006-8993(88)91501-6
    • MacLusky NJ, Naftolin F, Leranth C. Immunocytochemical evidence for direct synaptic connections between corticotrophin-releasing factor (CRF) and gonadotrophin-releasing hormone (GnRH)-containing neurons in the preoptic area of the rat. Brain Res (1988) 439(1-2):391-5. doi:10.1016/0006-8993(88)91501-6.
    • (1988) Brain Res , vol.439 , Issue.1-2 , pp. 391-395
    • MacLusky, N.J.1    Naftolin, F.2    Leranth, C.3
  • 147
    • 0036928788 scopus 로고    scopus 로고
    • Close juxtapositions between luteinizing hormone-releasing hormone-immunoreactive neurons and corticotropin-releasing factor-immunoreactive axons in the human diencephalon
    • doi:10.1210/jc.2002-020996
    • Dudas B, Merchenthaler I. Close juxtapositions between luteinizing hormone-releasing hormone-immunoreactive neurons and corticotropin-releasing factor-immunoreactive axons in the human diencephalon. J Clin Endocrinol Metab (2002) 87(12):5778-84. doi:10.1210/jc.2002-020996.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.12 , pp. 5778-5784
    • Dudas, B.1    Merchenthaler, I.2
  • 148
    • 84857126496 scopus 로고    scopus 로고
    • Inactivating KISS1 mutation and hypogonadotropic hypogonadism
    • doi:10.1056/NEJMoa1111184
    • Topaloglu AK, Tello JA, Kotan LD, Ozbek MN, Yilmaz MB, Erdogan S, et al. Inactivating KISS1 mutation and hypogonadotropic hypogonadism. N Engl J Med (2012) 366(7):629-35. doi:10.1056/NEJMoa1111184.
    • (2012) N Engl J Med , vol.366 , Issue.7 , pp. 629-635
    • Topaloglu, A.K.1    Tello, J.A.2    Kotan, L.D.3    Ozbek, M.N.4    Yilmaz, M.B.5    Erdogan, S.6
  • 150
    • 0141814637 scopus 로고    scopus 로고
    • Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
    • doi:10.1073/pnas.1834399100
    • de Roux N, Genin E, Carel JC, Matsuda F, Chaussain JL, Milgrom E. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc Natl Acad Sci U S A (2003) 100(19):10972-6. doi:10.1073/pnas.1834399100.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , Issue.19 , pp. 10972-6
    • de Roux, N.1    Genin, E.2    Carel, J.C.3    Matsuda, F.4    Chaussain, J.L.5    Milgrom, E.6
  • 151
    • 24944432237 scopus 로고    scopus 로고
    • Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats
    • doi:10.1210/en.2005-0195
    • Kinoshita M, Tsukamura H, Adachi S, Matsui H, Uenoyama Y, Iwata K, et al. Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats. Endocrinology (2005) 146(10):4431-6. doi:10.1210/en.2005-0195.
    • (2005) Endocrinology , vol.146 , Issue.10 , pp. 4431-4436
    • Kinoshita, M.1    Tsukamura, H.2    Adachi, S.3    Matsui, H.4    Uenoyama, Y.5    Iwata, K.6
  • 152
    • 67649665605 scopus 로고    scopus 로고
    • Postnatal development of an estradiol-kisspeptin positive feedback mechanism implicated in puberty onset
    • doi:10.1210/en.2008-1733
    • Clarkson J, Boon WC, Simpson ER, Herbison AE. Postnatal development of an estradiol-kisspeptin positive feedback mechanism implicated in puberty onset. Endocrinology (2009) 150(7):3214-20. doi:10.1210/en.2008-1733.
    • (2009) Endocrinology , vol.150 , Issue.7 , pp. 3214-3220
    • Clarkson, J.1    Boon, W.C.2    Simpson, E.R.3    Herbison, A.E.4
  • 153
    • 13444255980 scopus 로고    scopus 로고
    • Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54
    • doi:10.1073/pnas.0409330102
    • Messager S, Chatzidaki EE, Ma D, Hendrick AG, Zahn D, Dixon J, et al. Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci U S A (2005) 102(5):1761-6. doi:10.1073/pnas.0409330102.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , Issue.5 , pp. 1761-1766
    • Messager, S.1    Chatzidaki, E.E.2    Ma, D.3    Hendrick, A.G.4    Zahn, D.5    Dixon, J.6
  • 154
    • 13244255747 scopus 로고    scopus 로고
    • Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat
    • doi:10.1159/000083140
    • Irwig MS, Fraley GS, Smith JT, Acohido BV, Popa SM, Cunningham MJ, et al. Kisspeptin activation of gonadotropin releasing hormone neurons and regulation of KiSS-1 mRNA in the male rat. Neuroendocrinology (2004) 80(4):264-72. doi:10.1159/000083140.
    • (2004) Neuroendocrinology , vol.80 , Issue.4 , pp. 264-272
    • Irwig, M.S.1    Fraley, G.S.2    Smith, J.T.3    Acohido, B.V.4    Popa, S.M.5    Cunningham, M.J.6
  • 155
    • 30544450474 scopus 로고    scopus 로고
    • Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty
    • doi:10.1523/JNEUROSCI.3328-05.2005
    • Han SK, Gottsch ML, Lee KJ, Popa SM, Smith JT, Jakawich SK, et al. Activation of gonadotropin-releasing hormone neurons by kisspeptin as a neuroendocrine switch for the onset of puberty. J Neurosci (2005) 25(49):11349-56. doi:10.1523/JNEUROSCI.3328-05.2005.
    • (2005) J Neurosci , vol.25 , Issue.49 , pp. 11349-56
    • Han, S.K.1    Gottsch, M.L.2    Lee, K.J.3    Popa, S.M.4    Smith, J.T.5    Jakawich, S.K.6
  • 156
    • 51149105501 scopus 로고    scopus 로고
    • Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons
    • doi:10.1523/JNEUROSCI.1225-08.2008
    • Dumalska I, Wu M, Morozova E, Liu R, van den Pol A, Alreja M. Excitatory effects of the puberty-initiating peptide kisspeptin and group I metabotropic glutamate receptor agonists differentiate two distinct subpopulations of gonadotropin-releasing hormone neurons. J Neurosci (2008) 28(32):8003-13. doi:10.1523/JNEUROSCI.1225-08.2008.
    • (2008) J Neurosci , vol.28 , Issue.32 , pp. 8003-8013
    • Dumalska, I.1    Wu, M.2    Morozova, E.3    Liu, R.4    van den Pol, A.5    Alreja, M.6
  • 157
    • 41549121999 scopus 로고    scopus 로고
    • Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol
    • doi:10.1210/en.2007-1365
    • Pielecka-Fortuna J, Chu Z, Moenter SM. Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol. Endocrinology (2008) 149(4):1979-86. doi:10.1210/en.2007-1365.
    • (2008) Endocrinology , vol.149 , Issue.4 , pp. 1979-1986
    • Pielecka-Fortuna, J.1    Chu, Z.2    Moenter, S.M.3
  • 158
    • 33947363962 scopus 로고    scopus 로고
    • Sexual differentiation of Kiss1 gene expression in the brain of the rat
    • doi:10.1210/en.2006-1540
    • Kauffman AS, Gottsch ML, Roa J, Byquist AC, Crown A, Clifton DK, et al. Sexual differentiation of Kiss1 gene expression in the brain of the rat. Endocrinology (2007) 148(4):1774-83. doi:10.1210/en.2006-1540.
    • (2007) Endocrinology , vol.148 , Issue.4 , pp. 1774-1783
    • Kauffman, A.S.1    Gottsch, M.L.2    Roa, J.3    Byquist, A.C.4    Crown, A.5    Clifton, D.K.6
  • 159
    • 34248383233 scopus 로고    scopus 로고
    • Involvement of anteroventral periventricular metastin/kisspeptin neurons in estrogen positive feedback action on luteinizing hormone release in female rats
    • doi:10.1262/jrd.18146
    • Adachi S, Yamada S, Takatsu Y, Matsui H, Kinoshita M, Takase K, et al. Involvement of anteroventral periventricular metastin/kisspeptin neurons in estrogen positive feedback action on luteinizing hormone release in female rats. J Reprod Dev (2007) 53(2):367-78. doi:10.1262/jrd.18146.
    • (2007) J Reprod Dev , vol.53 , Issue.2 , pp. 367-378
    • Adachi, S.1    Yamada, S.2    Takatsu, Y.3    Matsui, H.4    Kinoshita, M.5    Takase, K.6
  • 160
    • 40749148050 scopus 로고    scopus 로고
    • Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent:the case for the rostral periventricular area of the third ventricle (RP3V)
    • doi:10.1016/j.brainresrev.2007.05.006
    • Herbison AE. Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent:the case for the rostral periventricular area of the third ventricle (RP3V). Brain Res Rev (2008) 57(2):277-87. doi:10.1016/j.brainresrev.2007.05.006.
    • (2008) Brain Res Rev , vol.57 , Issue.2 , pp. 277-287
    • Herbison, A.E.1
  • 161
    • 52049083005 scopus 로고    scopus 로고
    • Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge
    • doi:10.1523/JNEUROSCI.1775-08.2008
    • Clarkson J, d'Anglemont de Tassigny X, Moreno AS, Colledge WH, Herbison AE. Kisspeptin-GPR54 signaling is essential for preovulatory gonadotropin-releasing hormone neuron activation and the luteinizing hormone surge. J Neurosci (2008) 28(35):8691-7. doi:10.1523/JNEUROSCI.1775-08.2008.
    • (2008) J Neurosci , vol.28 , Issue.35 , pp. 8691-8697
    • Clarkson, J.1    d'Anglemont de Tassigny, X.2    Moreno, A.S.3    Colledge, W.H.4    Herbison, A.E.5
  • 162
    • 78650843257 scopus 로고    scopus 로고
    • Expression of fos and in vivo median eminence release of LHRH identifies an active role for preoptic area kisspeptin neurons in synchronized surges of LH and LHRH in the ewe
    • doi:10.1210/en.2010-0066
    • Hoffman GE, Le WW, Franceschini I, Caraty A, Advis JP. Expression of fos and in vivo median eminence release of LHRH identifies an active role for preoptic area kisspeptin neurons in synchronized surges of LH and LHRH in the ewe. Endocrinology (2011) 152(1):214-22. doi:10.1210/en.2010-0066.
    • (2011) Endocrinology , vol.152 , Issue.1 , pp. 214-222
    • Hoffman, G.E.1    Le, W.W.2    Franceschini, I.3    Caraty, A.4    Advis, J.P.5
  • 163
    • 84867815899 scopus 로고    scopus 로고
    • KNDy (kisspeptin/neurokinin B/dynorphin) neurons are activated during both pulsatile and surge secretion of LH in the ewe
    • doi:10.1210/en.2012-1357
    • Merkley CM, Porter KL, Coolen LM, Hileman SM, Billings HJ, Drews S, et al. KNDy (kisspeptin/neurokinin B/dynorphin) neurons are activated during both pulsatile and surge secretion of LH in the ewe. Endocrinology (2012) 153(11):5406-14. doi:10.1210/en.2012-1357.
    • (2012) Endocrinology , vol.153 , Issue.11 , pp. 5406-5414
    • Merkley, C.M.1    Porter, K.L.2    Coolen, L.M.3    Hileman, S.M.4    Billings, H.J.5    Drews, S.6
  • 164
    • 35948974359 scopus 로고    scopus 로고
    • Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B
    • doi:10.1210/en.2007-0961
    • Goodman RL, Lehman MN, Smith JT, Coolen LM, de Oliveira CV, Jafarzadehshirazi MR, et al. Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B. Endocrinology (2007) 148(12):5752-60. doi:10.1210/en.2007-0961.
    • (2007) Endocrinology , vol.148 , Issue.12 , pp. 5752-5760
    • Goodman, R.L.1    Lehman, M.N.2    Smith, J.T.3    Coolen, L.M.4    de Oliveira, C.V.5    Jafarzadehshirazi, M.R.6
  • 165
    • 22144455384 scopus 로고    scopus 로고
    • Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouse
    • doi:10.1210/en.2005-0323
    • Smith JT, Dungan HM, Stoll EA, Gottsch ML, Braun RE, Eacker SM, et al. Differential regulation of KiSS-1 mRNA expression by sex steroids in the brain of the male mouse. Endocrinology (2005) 146(7):2976-84. doi:10.1210/en.2005-0323.
    • (2005) Endocrinology , vol.146 , Issue.7 , pp. 2976-2984
    • Smith, J.T.1    Dungan, H.M.2    Stoll, E.A.3    Gottsch, M.L.4    Braun, R.E.5    Eacker, S.M.6
  • 166
    • 33847008349 scopus 로고    scopus 로고
    • KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season
    • doi:10.1210/en.2006-1435
    • Smith JT, Clay CM, Caraty A, Clarke IJ. KiSS-1 messenger ribonucleic acid expression in the hypothalamus of the ewe is regulated by sex steroids and season. Endocrinology (2007) 148(3):1150-7. doi:10.1210/en.2006-1435.
    • (2007) Endocrinology , vol.148 , Issue.3 , pp. 1150-1157
    • Smith, J.T.1    Clay, C.M.2    Caraty, A.3    Clarke, I.J.4
  • 167
    • 71949094687 scopus 로고    scopus 로고
    • Kisspeptin neurons in the ovine arcuate nucleus and preoptic area are involved in the preovulatory luteinizing hormone surge
    • doi:10.1210/en.2009-0712
    • Smith JT, Li Q, Pereira A, Clarke IJ. Kisspeptin neurons in the ovine arcuate nucleus and preoptic area are involved in the preovulatory luteinizing hormone surge. Endocrinology (2009) 150(12):5530-8. doi:10.1210/en.2009-0712.
    • (2009) Endocrinology , vol.150 , Issue.12 , pp. 5530-5538
    • Smith, J.T.1    Li, Q.2    Pereira, A.3    Clarke, I.J.4
  • 168
    • 73649083725 scopus 로고    scopus 로고
    • The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus:sex differences and effects of prenatal testosterone in sheep
    • doi:10.1210/en.2009-0541
    • Cheng G, Coolen LM, Padmanabhan V, Goodman RL, Lehman MN. The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus:sex differences and effects of prenatal testosterone in sheep. Endocrinology (2010) 151(1):301-11. doi:10.1210/en.2009-0541.
    • (2010) Endocrinology , vol.151 , Issue.1 , pp. 301-311
    • Cheng, G.1    Coolen, L.M.2    Padmanabhan, V.3    Goodman, R.L.4    Lehman, M.N.5
  • 169
    • 77954895859 scopus 로고    scopus 로고
    • Minireview:kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus:a central node in the control of gonadotropin-releasing hormone secretion
    • doi:10.1210/en.2010-0022
    • Lehman MN, Coolen LM, Goodman RL. Minireview:kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus:a central node in the control of gonadotropin-releasing hormone secretion. Endocrinology (2010) 151(8):3479-89. doi:10.1210/en.2010-0022.
    • (2010) Endocrinology , vol.151 , Issue.8 , pp. 3479-3489
    • Lehman, M.N.1    Coolen, L.M.2    Goodman, R.L.3
  • 170
    • 77956043908 scopus 로고    scopus 로고
    • Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus
    • doi:10.1210/en.2010-0223
    • Ramaswamy S, Seminara SB, Ali B, CiofiP, Amin NA, Plant TM. Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus. Endocrinology (2010) 151(9):4494-503. doi:10.1210/en.2010-0223.
    • (2010) Endocrinology , vol.151 , Issue.9 , pp. 4494-4503
    • Ramaswamy, S.1    Seminara, S.B.2    Ali, B.3    Ciofi, P.4    Amin, N.A.5    Plant, T.M.6
  • 171
    • 61349091041 scopus 로고    scopus 로고
    • TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction
    • doi:10.1038/ng.306
    • Topaloglu AK, Reimann F, Guclu M, Yalin AS, Kotan LD, Porter KM, et al. TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction. Nat Genet (2009) 41(3):354-8. doi:10.1038/ng.306.
    • (2009) Nat Genet , vol.41 , Issue.3 , pp. 354-358
    • Topaloglu, A.K.1    Reimann, F.2    Guclu, M.3    Yalin, A.S.4    Kotan, L.D.5    Porter, K.M.6
  • 172
    • 70349898626 scopus 로고    scopus 로고
    • Hypogonadotropic hypogonadism due to a novel missense mutation in the first extracellular loop of the neurokinin B receptor
    • doi:10.1210/jc.2009-0551
    • Guran T, Tolhurst G, Bereket A, Rocha N, Porter K, Turan S, et al. Hypogonadotropic hypogonadism due to a novel missense mutation in the first extracellular loop of the neurokinin B receptor. J Clin Endocrinol Metab (2009) 94(10):3633-9. doi:10.1210/jc.2009-0551.
    • (2009) J Clin Endocrinol Metab , vol.94 , Issue.10 , pp. 3633-3639
    • Guran, T.1    Tolhurst, G.2    Bereket, A.3    Rocha, N.4    Porter, K.5    Turan, S.6
  • 173
    • 73349127165 scopus 로고    scopus 로고
    • Neurokinin 3 receptor immunoreactivity in the septal region, preoptic area and hypothalamus of the female sheep:colocalisation in neurokinin B cells of the arcuate nucleus but not in gonadotrophin-releasing hormone neurones
    • doi:10.1111/j.1365-2826.2009.01930.x
    • Amstalden M, Coolen LM, Hemmerle AM, Billings HJ, Connors JM, Goodman RL, et al. Neurokinin 3 receptor immunoreactivity in the septal region, preoptic area and hypothalamus of the female sheep:colocalisation in neurokinin B cells of the arcuate nucleus but not in gonadotrophin-releasing hormone neurones. J Neuroendocrinol (2010) 22(1):1-12. doi:10.1111/j.1365-2826.2009.01930.x.
    • (2010) J Neuroendocrinol , vol.22 , Issue.1 , pp. 1-12
    • Amstalden, M.1    Coolen, L.M.2    Hemmerle, A.M.3    Billings, H.J.4    Connors, J.M.5    Goodman, R.L.6
  • 174
    • 80054878769 scopus 로고    scopus 로고
    • Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse
    • doi:10.1210/en.2011-1143
    • Navarro VM, Gottsch ML, Wu M, Garcia-Galiano D, Hobbs SJ, Bosch MA, et al. Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse. Endocrinology (2011) 152(11):4265-75. doi:10.1210/en.2011-1143.
    • (2011) Endocrinology , vol.152 , Issue.11 , pp. 4265-4275
    • Navarro, V.M.1    Gottsch, M.L.2    Wu, M.3    Garcia-Galiano, D.4    Hobbs, S.J.5    Bosch, M.A.6
  • 175
    • 0019993366 scopus 로고
    • Antagonist of gonadotropin-releasing hormone blocks naloxone-induced elevations in serum luteinizing hormone
    • doi:10.1159/000123399
    • Blank MS, Roberts DL. Antagonist of gonadotropin-releasing hormone blocks naloxone-induced elevations in serum luteinizing hormone. Neuroendocrinology (1982) 35(5):309-12. doi:10.1159/000123399.
    • (1982) Neuroendocrinology , vol.35 , Issue.5 , pp. 309-312
    • Blank, M.S.1    Roberts, D.L.2
  • 176
    • 0021338316 scopus 로고
    • Site of action for beta-endorphin-induced changes in plasma luteinizing hormone and prolactin in the ovariectomized rat
    • doi:10.1016/0024-3205(84)90061-4
    • Wiesner JB, Koenig JI, Krulich L, Moss RL. Site of action for beta-endorphin-induced changes in plasma luteinizing hormone and prolactin in the ovariectomized rat. Life Sci (1984) 34(15):1463-73. doi:10.1016/0024-3205(84)90061-4.
    • (1984) Life Sci , vol.34 , Issue.15 , pp. 1463-1473
    • Wiesner, J.B.1    Koenig, J.I.2    Krulich, L.3    Moss, R.L.4
  • 177
    • 0019853947 scopus 로고
    • Beta-endorphin and dynorphin control serum luteinizing hormone level in immature female rats
    • doi:10.1038/294757a0
    • Schulz R, Wilhelm A, Pirke KM, Gramsch C, Herz A. Beta-endorphin and dynorphin control serum luteinizing hormone level in immature female rats. Nature (1981) 294(5843):757-9. doi:10.1038/294757a0.
    • (1981) Nature , vol.294 , Issue.5843 , pp. 757-759
    • Schulz, R.1    Wilhelm, A.2    Pirke, K.M.3    Gramsch, C.4    Herz, A.5
  • 178
    • 0442323564 scopus 로고    scopus 로고
    • Close anatomical associations between beta-endorphin and luteinizing hormone-releasing hormone neuronal systems in the human diencephalon
    • doi:10.1016/j.neuroscience.2003.11.021
    • Dudas B, Merchenthaler I. Close anatomical associations between beta-endorphin and luteinizing hormone-releasing hormone neuronal systems in the human diencephalon. Neuroscience (2004) 124(1):221-9. doi:10.1016/j.neuroscience.2003.11.021.
    • (2004) Neuroscience , vol.124 , Issue.1 , pp. 221-229
    • Dudas, B.1    Merchenthaler, I.2
  • 179
    • 0035181609 scopus 로고    scopus 로고
    • Catecholaminergic axons innervate LH-releasing hormone immunoreactive neurons of the human diencephalon
    • doi:10.1210/jc.86.11.5620
    • Dudas B, Merchenthaler I. Catecholaminergic axons innervate LH-releasing hormone immunoreactive neurons of the human diencephalon. J Clin Endocrinol Metab (2001) 86(11):5620-6. doi:10.1210/jc.86.11.5620.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.11 , pp. 5620-5626
    • Dudas, B.1    Merchenthaler, I.2
  • 180
    • 0038021495 scopus 로고    scopus 로고
    • Topography and associations of leu-enkephalin and luteinizing hormone-releasing hormone neuronal systems in the human diencephalon
    • doi:10.1210/jc.2002-021416
    • Dudas B, Merchenthaler I. Topography and associations of leu-enkephalin and luteinizing hormone-releasing hormone neuronal systems in the human diencephalon. J Clin Endocrinol Metab (2003) 88(4):1842-8. doi:10.1210/jc.2002-021416.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.4 , pp. 1842-1848
    • Dudas, B.1    Merchenthaler, I.2
  • 181
    • 0018771147 scopus 로고
    • Enkephalins and pituitary hormone release:modification of responsiveness to LHRH
    • doi:10.1159/000178989
    • May PB, Mittler JC, Ertel NH. Enkephalins and pituitary hormone release:modification of responsiveness to LHRH. Horm Res (1979) 10(2-3):57-63. doi:10.1159/000178989.
    • (1979) Horm Res , vol.10 , Issue.2-3 , pp. 57-63
    • May, P.B.1    Mittler, J.C.2    Ertel, N.H.3
  • 182
    • 80053244697 scopus 로고    scopus 로고
    • Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus
    • doi:10.1002/cne.22716
    • Porteous R, Petersen SL, Yeo SH, Bhattarai JP, CiofiP, de Tassigny XD, et al. Kisspeptin neurons co-express met-enkephalin and galanin in the rostral periventricular region of the female mouse hypothalamus. J Comp Neurol (2011) 519(17):3456-69. doi:10.1002/cne.22716.
    • (2011) J Comp Neurol , vol.519 , Issue.17 , pp. 3456-3469
    • Porteous, R.1    Petersen, S.L.2    Yeo, S.H.3    Bhattarai, J.P.4    Ciofi, P.5    de Tassigny, X.D.6
  • 183
    • 67650462851 scopus 로고    scopus 로고
    • Dynorphin immunoreactive fibers contact GnRH neurons in the human hypothalamus
    • doi:10.1177/1933719109336619
    • Dahl SK, Amstalden M, Coolen L, Fitzgerald M, Lehman M. Dynorphin immunoreactive fibers contact GnRH neurons in the human hypothalamus. Reprod Sci (2009) 16(8):781-7. doi:10.1177/1933719109336619.
    • (2009) Reprod Sci , vol.16 , Issue.8 , pp. 781-787
    • Dahl, S.K.1    Amstalden, M.2    Coolen, L.3    Fitzgerald, M.4    Lehman, M.5
  • 184
    • 0034726675 scopus 로고    scopus 로고
    • A novel avian hypothalamic peptide inhibiting gonadotropin release
    • doi:10.1006/bbrc.2000.3350
    • Tsutsui K, Saigoh E, Ukena K, Teranishi H, Fujisawa Y, Kikuchi M, et al. A novel avian hypothalamic peptide inhibiting gonadotropin release. Biochem Biophys Res Commun (2000) 275(2):661-7. doi:10.1006/bbrc.2000.3350.
    • (2000) Biochem Biophys Res Commun , vol.275 , Issue.2 , pp. 661-667
    • Tsutsui, K.1    Saigoh, E.2    Ukena, K.3    Teranishi, H.4    Fujisawa, Y.5    Kikuchi, M.6
  • 185
    • 0037810833 scopus 로고    scopus 로고
    • Gonadotropin-inhibitory peptide in song sparrows (Melospiza melodia) in different reproductive conditions, and in house sparrows (Passer domesticus) relative to chicken-gonadotropin-releasing hormone
    • doi:10.1046/j.1365-2826.2003.01062.x
    • Bentley GE, Perfito N, Ukena K, Tsutsui K, Wingfield JC. Gonadotropin-inhibitory peptide in song sparrows (Melospiza melodia) in different reproductive conditions, and in house sparrows (Passer domesticus) relative to chicken-gonadotropin-releasing hormone. J Neuroendocrinol (2003) 15(8):794-802. doi:10.1046/j.1365-2826.2003.01062.x.
    • (2003) J Neuroendocrinol , vol.15 , Issue.8 , pp. 794-802
    • Bentley, G.E.1    Perfito, N.2    Ukena, K.3    Tsutsui, K.4    Wingfield, J.C.5
  • 186
    • 37549002536 scopus 로고    scopus 로고
    • Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin-releasing hormone-I and -II neurons in European starling brain
    • doi:10.1210/en.2007-0983
    • Ubuka T, Kim S, Huang YC, Reid J, Jiang J, Osugi T, et al. Gonadotropin-inhibitory hormone neurons interact directly with gonadotropin-releasing hormone-I and -II neurons in European starling brain. Endocrinology (2008) 149(1):268-78. doi:10.1210/en.2007-0983.
    • (2008) Endocrinology , vol.149 , Issue.1 , pp. 268-278
    • Ubuka, T.1    Kim, S.2    Huang, Y.C.3    Reid, J.4    Jiang, J.5    Osugi, T.6
  • 187
    • 0034306368 scopus 로고    scopus 로고
    • New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals
    • doi:10.1038/35036326
    • Hinuma S, Shintani Y, Fukusumi S, Iijima N, Matsumoto Y, Hosoya M, et al. New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. Nat Cell Biol (2000) 2(10):703-8. doi:10.1038/35036326.
    • (2000) Nat Cell Biol , vol.2 , Issue.10 , pp. 703-708
    • Hinuma, S.1    Shintani, Y.2    Fukusumi, S.3    Iijima, N.4    Matsumoto, Y.5    Hosoya, M.6
  • 188
    • 0142070854 scopus 로고    scopus 로고
    • Localization and neuronal response of RFamide related peptides in the rat central nervous system
    • doi:10.1016/S0006-8993(03)02877-4
    • Yano T, Iijima N, Kakihara K, Hinuma S, Tanaka M, Ibata Y. Localization and neuronal response of RFamide related peptides in the rat central nervous system. Brain Res (2003) 982(2):156-67. doi:10.1016/S0006-8993(03)02877-4.
    • (2003) Brain Res , vol.982 , Issue.2 , pp. 156-167
    • Yano, T.1    Iijima, N.2    Kakihara, K.3    Hinuma, S.4    Tanaka, M.5    Ibata, Y.6
  • 189
    • 4444303813 scopus 로고    scopus 로고
    • Developmental expression of RFamide-related peptides in the rat central nervous system
    • doi:10.1016/j.devbrainres.2004.06.008
    • Yano T, Iijima N, Hinuma S, Tanaka M, Ibata Y. Developmental expression of RFamide-related peptides in the rat central nervous system. Brain Res Dev Brain Res (2004) 152(2):109-20. doi:10.1016/j.devbrainres.2004.06.008.
    • (2004) Brain Res Dev Brain Res , vol.152 , Issue.2 , pp. 109-120
    • Yano, T.1    Iijima, N.2    Hinuma, S.3    Tanaka, M.4    Ibata, Y.5
  • 190
    • 33144478638 scopus 로고    scopus 로고
    • Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals
    • doi:10.1073/pnas.0511003103
    • Kriegsfeld LJ, Mei DF, Bentley GE, Ubuka T, Mason AO, Inoue K, et al. Identification and characterization of a gonadotropin-inhibitory system in the brains of mammals. Proc Natl Acad Sci U S A (2006) 103(7):2410-5. doi:10.1073/pnas.0511003103.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.7 , pp. 2410-2415
    • Kriegsfeld, L.J.1    Mei, D.F.2    Bentley, G.E.3    Ubuka, T.4    Mason, A.O.5    Inoue, K.6
  • 191
    • 33748483639 scopus 로고    scopus 로고
    • Interactions of gonadotropin-releasing hormone (GnRH) and gonadotropin-inhibitory hormone (GnIH) in birds and mammals
    • doi:10.1002/jez.a.306
    • Bentley GE, Kriegsfeld LJ, Osugi T, Ukena K, O'Brien S, Perfito N, et al. Interactions of gonadotropin-releasing hormone (GnRH) and gonadotropin-inhibitory hormone (GnIH) in birds and mammals. J Exp Zool A Comp Exp Biol (2006) 305(9):807-14. doi:10.1002/jez.a.306.
    • (2006) J Exp Zool A Comp Exp Biol , vol.305 , Issue.9 , pp. 807-814
    • Bentley, G.E.1    Kriegsfeld, L.J.2    Osugi, T.3    Ukena, K.4    O'Brien, S.5    Perfito, N.6
  • 192
    • 62749163075 scopus 로고    scopus 로고
    • Cells expressing RFamide-related peptide-1/3, the mammalian gonadotropin-inhibitory hormone orthologs, are not hypophysiotropic neuroendocrine neurons in the rat
    • doi:10.1210/en.2008-1287
    • Rizwan MZ, Porteous R, Herbison AE, Anderson GM. Cells expressing RFamide-related peptide-1/3, the mammalian gonadotropin-inhibitory hormone orthologs, are not hypophysiotropic neuroendocrine neurons in the rat. Endocrinology (2009) 150(3):1413-20. doi:10.1210/en.2008-1287.
    • (2009) Endocrinology , vol.150 , Issue.3 , pp. 1413-1420
    • Rizwan, M.Z.1    Porteous, R.2    Herbison, A.E.3    Anderson, G.M.4
  • 193
    • 54349094522 scopus 로고    scopus 로고
    • Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain:a novel medium for seasonal breeding in the sheep
    • doi:10.1210/en.2008-0581
    • Smith JT, Coolen LM, Kriegsfeld LJ, Sari IP, Jaafarzadehshirazi MR, Maltby M, et al. Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain:a novel medium for seasonal breeding in the sheep. Endocrinology (2008) 149(11):5770-82. doi:10.1210/en.2008-0581.
    • (2008) Endocrinology , vol.149 , Issue.11 , pp. 5770-5782
    • Smith, J.T.1    Coolen, L.M.2    Kriegsfeld, L.J.3    Sari, I.P.4    Jaafarzadehshirazi, M.R.5    Maltby, M.6
  • 194
    • 70350127131 scopus 로고    scopus 로고
    • Melanin-concentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation, linking energy balance to reproduction
    • doi:10.1073/pnas.0908200106
    • Wu M, Dumalska I, Morozova E, van den Pol A, Alreja M. Melanin-concentrating hormone directly inhibits GnRH neurons and blocks kisspeptin activation, linking energy balance to reproduction. Proc Natl Acad Sci U S A (2009) 106(40):17217-22. doi:10.1073/pnas.0908200106.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.40 , pp. 17217-22
    • Wu, M.1    Dumalska, I.2    Morozova, E.3    van den Pol, A.4    Alreja, M.5
  • 195
    • 33751524344 scopus 로고    scopus 로고
    • Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat
    • doi:10.1016/j.yhbeh.2006.09.009
    • Johnson MA, Tsutsui K, Fraley GS. Rat RFamide-related peptide-3 stimulates GH secretion, inhibits LH secretion, and has variable effects on sex behavior in the adult male rat. Horm Behav (2007) 51(1):171-80. doi:10.1016/j.yhbeh.2006.09.009.
    • (2007) Horm Behav , vol.51 , Issue.1 , pp. 171-180
    • Johnson, M.A.1    Tsutsui, K.2    Fraley, G.S.3
  • 196
    • 54349102278 scopus 로고    scopus 로고
    • Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion
    • doi:10.1210/en.2008-0575
    • Clarke IJ, Sari IP, Qi Y, Smith JT, Parkington HC, Ubuka T, et al. Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion. Endocrinology (2008) 149(11):5811-21. doi:10.1210/en.2008-0575.
    • (2008) Endocrinology , vol.149 , Issue.11 , pp. 5811-5821
    • Clarke, I.J.1    Sari, I.P.2    Qi, Y.3    Smith, J.T.4    Parkington, H.C.5    Ubuka, T.6
  • 197
    • 55049131753 scopus 로고    scopus 로고
    • Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats
    • doi:10.1677/JOE-08-0197
    • Murakami M, Matsuzaki T, Iwasa T, Yasui T, Irahara M, Osugi T, et al. Hypophysiotropic role of RFamide-related peptide-3 in the inhibition of LH secretion in female rats. J Endocrinol (2008) 199(1):105-12. doi:10.1677/JOE-08-0197.
    • (2008) J Endocrinol , vol.199 , Issue.1 , pp. 105-112
    • Murakami, M.1    Matsuzaki, T.2    Iwasa, T.3    Yasui, T.4    Irahara, M.5    Osugi, T.6
  • 198
    • 64049111188 scopus 로고    scopus 로고
    • Bovine C-terminal octapeptide of RFamide-related peptide-3 suppresses luteinizing hormone (LH) secretion from the pituitary as well as pulsatile LH secretion in bovines
    • doi:10.1016/j.domaniend.2009.02.001
    • Kadokawa H, Shibata M, Tanaka Y, Kojima T, Matsumoto K, Oshima K, et al. Bovine C-terminal octapeptide of RFamide-related peptide-3 suppresses luteinizing hormone (LH) secretion from the pituitary as well as pulsatile LH secretion in bovines. Domest Anim Endocrinol (2009) 36(4):219-24. doi:10.1016/j.domaniend.2009.02.001.
    • (2009) Domest Anim Endocrinol , vol.36 , Issue.4 , pp. 219-224
    • Kadokawa, H.1    Shibata, M.2    Tanaka, Y.3    Kojima, T.4    Matsumoto, K.5    Oshima, K.6
  • 199
    • 0035896464 scopus 로고    scopus 로고
    • Distribution of novel RFamide-related peptide-like immunoreactivity in the mouse central nervous system
    • doi:10.1016/S0304-3940(01)01583-X
    • Ukena K, Tsutsui K. Distribution of novel RFamide-related peptide-like immunoreactivity in the mouse central nervous system. Neurosci Lett (2001) 300(3):153-6. doi:10.1016/S0304-3940(01)01583-X.
    • (2001) Neurosci Lett , vol.300 , Issue.3 , pp. 153-156
    • Ukena, K.1    Tsutsui, K.2
  • 200
    • 70449492573 scopus 로고    scopus 로고
    • Gonadotropin-inhibitory hormone identification, cDNA cloning, and distribution in rhesus macaque brain
    • doi:10.1002/cne.22191
    • Ubuka T, Lai H, Kitani M, Suzuuchi A, Pham V, Cadigan PA, et al. Gonadotropin-inhibitory hormone identification, cDNA cloning, and distribution in rhesus macaque brain. J Comp Neurol (2009) 517(6):841-55. doi:10.1002/cne.22191.
    • (2009) J Comp Neurol , vol.517 , Issue.6 , pp. 841-855
    • Ubuka, T.1    Lai, H.2    Kitani, M.3    Suzuuchi, A.4    Pham, V.5    Cadigan, P.A.6
  • 201
    • 84864378842 scopus 로고    scopus 로고
    • Orexin a suppresses gonadotropin-releasing hormone (GnRH) neuron activity in the mouse
    • doi:10.1210/en.2012-1300
    • Gaskins GT, Moenter SM. Orexin a suppresses gonadotropin-releasing hormone (GnRH) neuron activity in the mouse. Endocrinology (2012) 153(8):3850-60. doi:10.1210/en.2012-1300.
    • (2012) Endocrinology , vol.153 , Issue.8 , pp. 3850-3860
    • Gaskins, G.T.1    Moenter, S.M.2
  • 202
    • 0035179520 scopus 로고    scopus 로고
    • Evidence that orexin-containing neurones provide direct input to gonadotropin-releasing hormone neurones in the ovine hypothalamus
    • doi:10.1046/j.1365-2826.2001.00719.x
    • Iqbal J, Pompolo S, Sakurai T, Clarke IJ. Evidence that orexin-containing neurones provide direct input to gonadotropin-releasing hormone neurones in the ovine hypothalamus. J Neuroendocrinol (2001) 13(12):1033-41. doi:10.1046/j.1365-2826.2001.00719.x.
    • (2001) J Neuroendocrinol , vol.13 , Issue.12 , pp. 1033-1041
    • Iqbal, J.1    Pompolo, S.2    Sakurai, T.3    Clarke, I.J.4
  • 203
    • 0035900222 scopus 로고    scopus 로고
    • Appositions between cocaine and amphetamine-related transcript- and gonadotropin releasing hormone-immunoreactive neurons in the hypothalamus of the Siberian hamster
    • doi:10.1016/S0304-3940(01)02291-1
    • Leslie RA, Sanders SJ, Anderson SI, Schuhler S, Horan TL, Ebling FJ. Appositions between cocaine and amphetamine-related transcript- and gonadotropin releasing hormone-immunoreactive neurons in the hypothalamus of the Siberian hamster. Neurosci Lett (2001) 314(3):111-4. doi:10.1016/S0304-3940(01)02291-1.
    • (2001) Neurosci Lett , vol.314 , Issue.3 , pp. 111-114
    • Leslie, R.A.1    Sanders, S.J.2    Anderson, S.I.3    Schuhler, S.4    Horan, T.L.5    Ebling, F.J.6
  • 204
    • 0026025907 scopus 로고
    • Hypothalamic sites of catecholamine inhibition of luteinizing hormone in the anestrous ewe
    • doi:10.1095/biolreprod44.3.476
    • Havern RL, Whisnant CS, Goodman RL. Hypothalamic sites of catecholamine inhibition of luteinizing hormone in the anestrous ewe. Biol Reprod (1991) 44(3):476-82. doi:10.1095/biolreprod44.3.476.
    • (1991) Biol Reprod , vol.44 , Issue.3 , pp. 476-482
    • Havern, R.L.1    Whisnant, C.S.2    Goodman, R.L.3
  • 205
    • 0017103792 scopus 로고
    • Catecholamine involvement in episodic luteinizing hormone release in adult ovariectomized rats
    • doi:10.1210/endo-99-3-651
    • Drouva SV, Gallo RV. Catecholamine involvement in episodic luteinizing hormone release in adult ovariectomized rats. Endocrinology (1976) 99(3):651-8. doi:10.1210/endo-99-3-651.
    • (1976) Endocrinology , vol.99 , Issue.3 , pp. 651-658
    • Drouva, S.V.1    Gallo, R.V.2
  • 206
    • 0030614358 scopus 로고    scopus 로고
    • Alpha1-adrenergic receptor blockade blocks LH secretion but not LHRH cFos activation
    • doi:10.1016/S0006-8993(96)01269-3
    • Le WW, Berghorn KA, Smith MS, Hoffman GE. Alpha1-adrenergic receptor blockade blocks LH secretion but not LHRH cFos activation. Brain Res (1997) 747(2):236-45. doi:10.1016/S0006-8993(96)01269-3.
    • (1997) Brain Res , vol.747 , Issue.2 , pp. 236-245
    • Le, W.W.1    Berghorn, K.A.2    Smith, M.S.3    Hoffman, G.E.4
  • 207
    • 0020599818 scopus 로고
    • Evidence that norepinephrine and epinephrine systems mediate the stimulatory effects of ovarian hormones on luteinizing hormone and luteinizing hormone-releasing hormone
    • doi:10.1210/endo-113-4-1431
    • Adler BA, Johnson MD, Lynch CO, Crowley WR. Evidence that norepinephrine and epinephrine systems mediate the stimulatory effects of ovarian hormones on luteinizing hormone and luteinizing hormone-releasing hormone. Endocrinology (1983) 113(4):1431-8. doi:10.1210/endo-113-4-1431.
    • (1983) Endocrinology , vol.113 , Issue.4 , pp. 1431-1438
    • Adler, B.A.1    Johnson, M.D.2    Lynch, C.O.3    Crowley, W.R.4
  • 208
    • 0024661436 scopus 로고
    • Catecholamine inhibition of luteinizing hormone secretion in isolated pig pituitary cells
    • doi:10.1095/biolreprod40.5.914
    • Li PH. Catecholamine inhibition of luteinizing hormone secretion in isolated pig pituitary cells. Biol Reprod (1989) 40(5):914-9. doi:10.1095/biolreprod40.5.914.
    • (1989) Biol Reprod , vol.40 , Issue.5 , pp. 914-919
    • Li, P.H.1
  • 209
    • 0022181581 scopus 로고
    • Organization of LHRH cells:differential apposition of neurotensin, substance P and catecholamine axons
    • doi:10.1016/0196-9781(85)90110-X
    • Hoffman GE. Organization of LHRH cells:differential apposition of neurotensin, substance P and catecholamine axons. Peptides (1985) 6(3):439-61. doi:10.1016/0196-9781(85)90110-X.
    • (1985) Peptides , vol.6 , Issue.3 , pp. 439-461
    • Hoffman, G.E.1
  • 210
    • 0024603246 scopus 로고
    • Histamine-immunoreactive nerve fibers in the rat brain
    • doi:10.1016/0306-4522(89)90007-9
    • Panula P, Pirvola U, Auvinen S, Airaksinen MS. Histamine-immunoreactive nerve fibers in the rat brain. Neuroscience (1989) 28(3):585-610. doi:10.1016/0306-4522(89)90007-9.
    • (1989) Neuroscience , vol.28 , Issue.3 , pp. 585-610
    • Panula, P.1    Pirvola, U.2    Auvinen, S.3    Airaksinen, M.S.4
  • 211
    • 0002462887 scopus 로고
    • Rhinencephalic involvement in pituitary activation by intraventricular histamine in the rabbit under nembutal anesthesia
    • Sawyer CH. Rhinencephalic involvement in pituitary activation by intraventricular histamine in the rabbit under nembutal anesthesia. Am J Physiol (1955) 180(1):37-46.
    • (1955) Am J Physiol , vol.180 , Issue.1 , pp. 37-46
    • Sawyer, C.H.1
  • 212
    • 0029053512 scopus 로고
    • Histamine directly stimulates gonadotropin-releasing hormone secretion from GT1-1 cells via H1 receptors coupled to phosphoinositide hydrolysis
    • doi:10.1210/en.136.7.2967
    • Noris G, Hol D, Clapp C, Martinez de la Escalera G. Histamine directly stimulates gonadotropin-releasing hormone secretion from GT1-1 cells via H1 receptors coupled to phosphoinositide hydrolysis. Endocrinology (1995) 136(7):2967-74. doi:10.1210/en.136.7.2967.
    • (1995) Endocrinology , vol.136 , Issue.7 , pp. 2967-2974
    • Noris, G.1    Hol, D.2    Clapp, C.3    Martinez de la Escalera, G.4
  • 213
    • 0142011167 scopus 로고    scopus 로고
    • Estrogen receptors and metabolic activity in the human tuberomamillary nucleus:changes in relation to sex, aging and Alzheimer's disease
    • doi:10.1016/S0006-8993(03)03347-X
    • Ishunina TA, van Heerikhuize JJ, Ravid R, Swaab DF. Estrogen receptors and metabolic activity in the human tuberomamillary nucleus:changes in relation to sex, aging and Alzheimer's disease. Brain Res (2003) 988(1-2):84-96. doi:10.1016/S0006-8993(03)03347-X.
    • (2003) Brain Res , vol.988 , Issue.1-2 , pp. 84-96
    • Ishunina, T.A.1    van Heerikhuize, J.J.2    Ravid, R.3    Swaab, D.F.4
  • 214
    • 0025642965 scopus 로고
    • GABA:a dominant neurotransmitter in the hypothalamus
    • doi:10.1002/cne.903020423
    • Decavel C, Van den Pol AN. GABA:a dominant neurotransmitter in the hypothalamus. J Comp Neurol (1990) 302(4):1019-37. doi:10.1002/cne.903020423.
    • (1990) J Comp Neurol , vol.302 , Issue.4 , pp. 1019-1037
    • Decavel, C.1    Van den Pol, A.N.2
  • 215
    • 0025635709 scopus 로고
    • Glutamate, the dominant excitatory transmitter in neuroendocrine regulation
    • doi:10.1126/science.1978759
    • van den Pol AN, Wuarin JP, Dudek FE. Glutamate, the dominant excitatory transmitter in neuroendocrine regulation. Science (1990) 250(4985):1276-8. doi:10.1126/science.1978759.
    • (1990) Science , vol.250 , Issue.4985 , pp. 1276-1278
    • van den Pol, A.N.1    Wuarin, J.P.2    Dudek, F.E.3
  • 216
    • 77955373756 scopus 로고    scopus 로고
    • The neurobiology of preovulatory and estradiol-induced gonadotropin-releasing hormone surges
    • doi:10.1210/er.2009-0023
    • Christian CA, Moenter SM. The neurobiology of preovulatory and estradiol-induced gonadotropin-releasing hormone surges. Endocr Rev (2010) 31(4):544-77. doi:10.1210/er.2009-0023.
    • (2010) Endocr Rev , vol.31 , Issue.4 , pp. 544-577
    • Christian, C.A.1    Moenter, S.M.2
  • 217
    • 0021812842 scopus 로고
    • Glutamic acid decarboxylase-containing axons synapse on LHRH neurons in the rat medial preoptic area
    • doi:10.1159/000124127
    • Leranth C, MacLusky NJ, Sakamoto H, Shanabrough M, Naftolin F. Glutamic acid decarboxylase-containing axons synapse on LHRH neurons in the rat medial preoptic area. Neuroendocrinology (1985) 40(6):536-9. doi:10.1159/000124127.
    • (1985) Neuroendocrinology , vol.40 , Issue.6 , pp. 536-539
    • Leranth, C.1    MacLusky, N.J.2    Sakamoto, H.3    Shanabrough, M.4    Naftolin, F.5
  • 218
    • 0033559431 scopus 로고    scopus 로고
    • GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic mice
    • Spergel DJ, Kruth U, Hanley DF, Sprengel R, Seeburg PH. GABA- and glutamate-activated channels in green fluorescent protein-tagged gonadotropin-releasing hormone neurons in transgenic mice. J Neurosci (1999) 19(6):2037-50.
    • (1999) J Neurosci , vol.19 , Issue.6 , pp. 2037-2050
    • Spergel, D.J.1    Kruth, U.2    Hanley, D.F.3    Sprengel, R.4    Seeburg, P.H.5
  • 219
    • 12244253710 scopus 로고    scopus 로고
    • Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons
    • doi:10.1210/me.2002-0163
    • DeFazio RA, Heger S, Ojeda SR, Moenter SM. Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons. Mol Endocrinol (2002) 16(12):2872-91. doi:10.1210/me.2002-0163.
    • (2002) Mol Endocrinol , vol.16 , Issue.12 , pp. 2872-2891
    • DeFazio, R.A.1    Heger, S.2    Ojeda, S.R.3    Moenter, S.M.4
  • 220
    • 0141680913 scopus 로고    scopus 로고
    • Metabolic regulation of fertility through presynaptic and postsynaptic signaling to gonadotropin-releasing hormone neurons
    • Sullivan SD, DeFazio RA, Moenter SM. Metabolic regulation of fertility through presynaptic and postsynaptic signaling to gonadotropin-releasing hormone neurons. J Neurosci (2003) 23(24):8578-85.
    • (2003) J Neurosci , vol.23 , Issue.24 , pp. 8578-8585
    • Sullivan, S.D.1    DeFazio, R.A.2    Moenter, S.M.3
  • 221
    • 0028985842 scopus 로고
    • Estradiol-17 beta and mu-opioid peptides rapidly hyperpolarize GnRH neurons:a cellular mechanism of negative feedback?
    • doi:10.1210/en.136.5.2341
    • Lagrange AH, Ronnekleiv OK, Kelly MJ. Estradiol-17 beta and mu-opioid peptides rapidly hyperpolarize GnRH neurons:a cellular mechanism of negative feedback? Endocrinology (1995) 136(5):2341-4. doi:10.1210/en.136.5.2341.
    • (1995) Endocrinology , vol.136 , Issue.5 , pp. 2341-2344
    • Lagrange, A.H.1    Ronnekleiv, O.K.2    Kelly, M.J.3
  • 222
    • 0036214661 scopus 로고    scopus 로고
    • Effect of GABA on GnRH neurons switches from depolarization to hyperpolarization at puberty in the female mouse
    • doi:10.1210/en.143.4.1459
    • Han SK, Abraham IM, Herbison AE. Effect of GABA on GnRH neurons switches from depolarization to hyperpolarization at puberty in the female mouse. Endocrinology (2002) 143(4):1459-66. doi:10.1210/en.143.4.1459.
    • (2002) Endocrinology , vol.143 , Issue.4 , pp. 1459-1466
    • Han, S.K.1    Abraham, I.M.2    Herbison, A.E.3
  • 223
    • 79959228560 scopus 로고    scopus 로고
    • Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones:towards an emerging consensus
    • doi:10.1111/j.1365-2826.2011.02145.x
    • Herbison AE, Moenter SM. Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones:towards an emerging consensus. J Neuroendocrinol (2011) 23(7):557-69. doi:10.1111/j.1365-2826.2011.02145.x.
    • (2011) J Neuroendocrinol , vol.23 , Issue.7 , pp. 557-569
    • Herbison, A.E.1    Moenter, S.M.2
  • 224
    • 68049139663 scopus 로고    scopus 로고
    • GABAA receptors mediate excitation in adult rat GnRH neurons
    • doi:10.1095/biolreprod.108.074583
    • Watanabe M, Sakuma Y, Kato M. GABAA receptors mediate excitation in adult rat GnRH neurons. Biol Reprod (2009) 81(2):327-32. doi:10.1095/biolreprod.108.074583.
    • (2009) Biol Reprod , vol.81 , Issue.2 , pp. 327-332
    • Watanabe, M.1    Sakuma, Y.2    Kato, M.3
  • 225
    • 78649837310 scopus 로고    scopus 로고
    • Retrograde endocannabinoid signaling reduces GABAergic synaptic transmission to gonadotropin-releasing hormone neurons
    • doi:10.1210/en.2010-0638
    • Farkas I, Kallo I, Deli L, Vida B, Hrabovszky E, Fekete C, et al. Retrograde endocannabinoid signaling reduces GABAergic synaptic transmission to gonadotropin-releasing hormone neurons. Endocrinology (2010) 151(12):5818-29. doi:10.1210/en.2010-0638.
    • (2010) Endocrinology , vol.151 , Issue.12 , pp. 5818-5829
    • Farkas, I.1    Kallo, I.2    Deli, L.3    Vida, B.4    Hrabovszky, E.5    Fekete, C.6
  • 226
    • 0028049121 scopus 로고
    • Glutamate-immunoreactive neurons and their gonadotropin-releasing hormone-neuronal interactions in the monkey hypothalamus
    • doi:10.1210/en.134.2.858
    • Goldsmith PC, Thind KK, Perera AD, Plant TM. Glutamate-immunoreactive neurons and their gonadotropin-releasing hormone-neuronal interactions in the monkey hypothalamus. Endocrinology (1994) 134(2):858-68. doi:10.1210/en.134.2.858.
    • (1994) Endocrinology , vol.134 , Issue.2 , pp. 858-868
    • Goldsmith, P.C.1    Thind, K.K.2    Perera, A.D.3    Plant, T.M.4
  • 227
    • 0347419240 scopus 로고    scopus 로고
    • Evidence for vesicular glutamate transporter synapses onto gonadotropin-releasing hormone and other neurons in the rat medial preoptic area
    • doi:10.1111/j.1460-9568.2003.03085.x
    • Kiss J, Kocsis K, Csaki A, Halasz B. Evidence for vesicular glutamate transporter synapses onto gonadotropin-releasing hormone and other neurons in the rat medial preoptic area. Eur J Neurosci (2003) 18(12):3267-78. doi:10.1111/j.1460-9568.2003.03085.x.
    • (2003) Eur J Neurosci , vol.18 , Issue.12 , pp. 3267-3278
    • Kiss, J.1    Kocsis, K.2    Csaki, A.3    Halasz, B.4
  • 228
    • 84870727063 scopus 로고    scopus 로고
    • Sex differences in the neurokinin B system in the human infundibular nucleus
    • doi:10.1210/jc.2012-1554
    • Taziaux M, Swaab DF, Bakker J. Sex differences in the neurokinin B system in the human infundibular nucleus. J Clin Endocrinol Metab (2012) 97(12):E2210-20. doi:10.1210/jc.2012-1554.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.12
    • Taziaux, M.1    Swaab, D.F.2    Bakker, J.3
  • 229
    • 79952570219 scopus 로고    scopus 로고
    • Endocrinology of the aging male
    • doi:10.1016/j.beem.2010.11.004
    • Araujo AB, Wittert GA. Endocrinology of the aging male. Best Pract Res Clin Endocrinol Metab (2011) 25(2):303-19. doi:10.1016/j.beem.2010.11.004.
    • (2011) Best Pract Res Clin Endocrinol Metab , vol.25 , Issue.2 , pp. 303-319
    • Araujo, A.B.1    Wittert, G.A.2
  • 230
    • 77957575434 scopus 로고    scopus 로고
    • Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men
    • doi:10.1152/ajpendo.00300.2010
    • Veldhuis JD, Takahashi PY, Keenan DM, Liu PY, Mielke KL, Weist SM. Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men. Am J Physiol Endocrinol Metab (2010) 299(4):E675-82. doi:10.1152/ajpendo.00300.2010.
    • (2010) Am J Physiol Endocrinol Metab , vol.299 , Issue.4
    • Veldhuis, J.D.1    Takahashi, P.Y.2    Keenan, D.M.3    Liu, P.Y.4    Mielke, K.L.5    Weist, S.M.6
  • 231
    • 77954414397 scopus 로고    scopus 로고
    • Identification of late-onset hypogonadism in middle-aged and elderly men
    • doi:10.1056/NEJMoa0911101
    • Wu FC, Tajar A, Beynon JM, Pye SR, Silman AJ, Finn JD, et al. Identification of late-onset hypogonadism in middle-aged and elderly men. N Engl J Med (2010) 363(2):123-35. doi:10.1056/NEJMoa0911101.
    • (2010) N Engl J Med , vol.363 , Issue.2 , pp. 123-135
    • Wu, F.C.1    Tajar, A.2    Beynon, J.M.3    Pye, S.R.4    Silman, A.J.5    Finn, J.D.6
  • 232
    • 0027293204 scopus 로고
    • Neuronal hypertrophy in the hypothalamus of older men
    • doi:10.1016/0197-4580(93)90119-V
    • Rance NE, Uswandi SV, McMullen NT. Neuronal hypertrophy in the hypothalamus of older men. Neurobiol Aging (1993) 14(4):337-42. doi:10.1016/0197-4580(93)90119-V.
    • (1993) Neurobiol Aging , vol.14 , Issue.4 , pp. 337-342
    • Rance, N.E.1    Uswandi, S.V.2    McMullen, N.T.3
  • 233
    • 0023411730 scopus 로고
    • Aging changes in synaptology of luteinizing hormone-releasing hormone neurons in male rat preoptic area
    • doi:10.1016/0306-4522(87)92976-9
    • Witkin JW. Aging changes in synaptology of luteinizing hormone-releasing hormone neurons in male rat preoptic area. Neuroscience (1987) 22(3):1003-13. doi:10.1016/0306-4522(87)92976-9.
    • (1987) Neuroscience , vol.22 , Issue.3 , pp. 1003-1013
    • Witkin, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.