Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men

American Journal of Physiology - Endocrinology and Metabolism

Volumn 299, Issue 4, 2010, Pages

  Veldhuis, Johannes D ^a   Takahashi, Paul Y ^a   Keenan, Daniel M ^b   Liu, Peter Y ^a,c   Mielke, Kristi L ^a   Weist, Suanne M ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Approximate entropy; Human; Leuteinizing hormone; Pulsatile; Secretion; Testosterone

Indexed keywords

ANDROGEN RECEPTOR; BICALUTAMIDE; FLUTAMIDE; LUTEINIZING HORMONE; PLACEBO; TESTOSTERONE; ANILIDE; ANTIANDROGEN; ESTRADIOL; NITRILE; SEX HORMONE BINDING GLOBULIN; TOLUENESULFONIC ACID DERIVATIVE;

ADULT; AGE; AGED; ARTICLE; CENTRAL NERVOUS SYSTEM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENTROPY; GONAD; HORMONE RESPONSE; HUMAN; HUMAN EXPERIMENT; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; NEGATIVE FEEDBACK; NORMAL HUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; BLOOD; CROSSOVER PROCEDURE; DRUG EFFECTS; FEEDBACK SYSTEM; HYPOPHYSIS ADRENAL SYSTEM; MIDDLE AGED; PHYSIOLOGY; SECRETION (PROCESS); STATISTICAL MODEL; YOUNG ADULT;

ADULT; AGE FACTORS; AGED; ANDROGEN ANTAGONISTS; ANILIDES; CENTRAL NERVOUS SYSTEM; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; ESTRADIOL; FEEDBACK; FLUTAMIDE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LINEAR MODELS; LUTEINIZING HORMONE; MALE; MIDDLE AGED; NITRILES; PITUITARY-ADRENAL SYSTEM; PROSPECTIVE STUDIES; RECEPTORS, ANDROGEN; SEX HORMONE-BINDING GLOBULIN; TESTOSTERONE; TOSYL COMPOUNDS; YOUNG ADULT;

EID: 77957575434     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00300.2010     Document Type: Article

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