메뉴 건너뛰기




Volumn 51, Issue 3, 2013, Pages 851-862

Geraniol ameliorates the motor behavior and neurotrophic factors inadequacy in MPTP-induced mice model of parkinson's disease

Author keywords

Neurodegeneration; Neuroprotective; Neurotrophic factors; Parkinson's disease

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOLAMINE; GERANIOL; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLUTATHIONE; MALONALDEHYDE; MESSENGER RNA; NEUROPROTECTIVE AGENT; NEUROTROPHIC FACTOR; TYROSINE 3 MONOOXYGENASE; VESICULAR MONOAMINE TRANSPORTER 2;

EID: 84885956424     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-013-0074-9     Document Type: Article
Times cited : (69)

References (67)
  • 1
    • 84914639435 scopus 로고
    • Estimation of nuclear population from microtome sections
    • 21015608 10.1002/ar.1090940210 1:STN:280:DyaH28%2FjtlOisQ%3D%3D
    • Abercrombie M (1946) Estimation of nuclear population from microtome sections. Anat Rec 94:239-247
    • (1946) Anat Rec , vol.94 , pp. 239-247
    • Abercrombie, M.1
  • 3
    • 0030805622 scopus 로고    scopus 로고
    • A generalized increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
    • 9282961 10.1046/j.1471-4159.1997.69031326.x 1:CAS:528:DyaK2sXls1Chu70%3D
    • Alam ZI, Daniel SE, Lees AJ, Marsden DC (1997) A generalized increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J Neurochem 69:1326-1329
    • (1997) J Neurochem , vol.69 , pp. 1326-1329
    • Alam, Z.I.1    Daniel, S.E.2    Lees, A.J.3    Marsden, D.C.4
  • 4
    • 0347480301 scopus 로고    scopus 로고
    • Neurotrophic factors and their receptors in human sensory neuropathies
    • 14699981 10.1016/S0079-6123(03)46030-5 1:CAS:528:DC%2BD2cXkslWlsA%3D%3D
    • Anand P (2004) Neurotrophic factors and their receptors in human sensory neuropathies. Prog Brain Res 146:477-492
    • (2004) Prog Brain Res , vol.146 , pp. 477-492
    • Anand, P.1
  • 5
    • 33846501598 scopus 로고    scopus 로고
    • GDNF family receptor complexes are emerging drug targets
    • 17218019 10.1016/j.tips.2006.12.005 1:CAS:528:DC%2BD2sXhtlCmu7g%3D
    • Bespalov MM, Saarma M (2007) GDNF family receptor complexes are emerging drug targets. Trends Pharmacol Sci 28:68-74
    • (2007) Trends Pharmacol Sci , vol.28 , pp. 68-74
    • Bespalov, M.M.1    Saarma, M.2
  • 6
    • 0346749428 scopus 로고    scopus 로고
    • Enriched environment confers resistance to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine and cocaine: Involvement of dopamine transporter and trophic factors
    • 14657156 1:CAS:528:DC%2BD3sXpvV2gt7g%3D
    • Bezard E, Dovero S, Belin D (2003) Enriched environment confers resistance to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors. J Neurosci 23:10999-11007
    • (2003) J Neurosci , vol.23 , pp. 10999-11007
    • Bezard, E.1    Dovero, S.2    Belin, D.3
  • 7
    • 33750607459 scopus 로고    scopus 로고
    • A partial GDNF depletion leads to earlier age related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra
    • 16889771 10.1016/j.expneurol.2006.06.006 1:CAS:528:DC%2BD28Xht1ShtbfL
    • Boger HA, Middaugh LD, Huang P, Zaman V, Smith AC, Hoffer BJ, Tomac AC (2006) A partial GDNF depletion leads to earlier age related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra. Exp Neurol 202:336-347
    • (2006) Exp Neurol , vol.202 , pp. 336-347
    • Boger, H.A.1    Middaugh, L.D.2    Huang, P.3    Zaman, V.4    Smith, A.C.5    Hoffer, B.J.6    Tomac, A.C.7
  • 8
    • 34548089172 scopus 로고    scopus 로고
    • Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice
    • 17699663 10.1523/JNEUROSCI.1067-07.2007 1:CAS:528:DC%2BD2sXhtVegt7nL
    • Boger HA, Middaugh LD, Patrick KS (2007) Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice. J Neurosci 27:8816-8825
    • (2007) J Neurosci , vol.27 , pp. 8816-8825
    • Boger, H.A.1    Middaugh, L.D.2    Patrick, K.S.3
  • 9
    • 44649122740 scopus 로고    scopus 로고
    • Altered vesicular dopamine storage in Parkinson's disease: A premature demise
    • 18471904 10.1016/j.tins.2008.02.010 1:CAS:528:DC%2BD1cXmvV2isb0%3D
    • Caudle WM, Colebrooke RE, Emson PC, Mille GW (2008) Altered vesicular dopamine storage in Parkinson's disease: a premature demise. Trends Neurosci 31:303-308
    • (2008) Trends Neurosci , vol.31 , pp. 303-308
    • Caudle, W.M.1    Colebrooke, R.E.2    Emson, P.C.3    Mille, G.W.4
  • 10
    • 62449132771 scopus 로고    scopus 로고
    • Nrf2 mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
    • 19196989 10.1073/pnas.0813361106 1:CAS:528:DC%2BD1MXislSkurg%3D
    • Chen PC, Vargas MR, Pani AK, Smeyne RJ, Johnson DA, Kan YW (2009) Nrf2 mediated neuroprotection in the MPTP mouse model of Parkinson's disease: critical role for the astrocyte. Proc Natl Acad Sci 106:2933-2938
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 2933-2938
    • Chen, P.C.1    Vargas, M.R.2    Pani, A.K.3    Smeyne, R.J.4    Johnson, D.A.5    Kan, Y.W.6
  • 12
    • 79957467314 scopus 로고    scopus 로고
    • Aging as a primary risk factor for Parkinson's disease: Evidence from studies of nonhuman primates
    • 21587290 10.1038/nrn3039 1:CAS:528:DC%2BC3MXmtF2lurw%3D
    • Collier TJ, Kanaan NM, Kordower JH (2011) Aging as a primary risk factor for Parkinson's disease: evidence from studies of nonhuman primates. Nat Rev Neurosci 12:359-366
    • (2011) Nat Rev Neurosci , vol.12 , pp. 359-366
    • Collier, T.J.1    Kanaan, N.M.2    Kordower, J.H.3
  • 13
    • 0032514206 scopus 로고    scopus 로고
    • GDNF administration induces recovery of the nigrostriatal dopaminergic system both in young and aged Parkinsonian mice
    • 9694229 10.1097/00001756-199807130-00039 1:CAS:528:DyaK1cXltVKlt7k%3D
    • Date I, Aoi M, Tomita S, Collins F, Ohmoto T (1998) GDNF administration induces recovery of the nigrostriatal dopaminergic system both in young and aged Parkinsonian mice. NeuroReport 9:2365-2369
    • (1998) NeuroReport , vol.9 , pp. 2365-2369
    • Date, I.1    Aoi, M.2    Tomita, S.3    Collins, F.4    Ohmoto, T.5
  • 14
    • 28744446884 scopus 로고    scopus 로고
    • Lentivector mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model
    • 16307601 10.1111/j.1460-9568.2005.04414.x
    • Dowd E, Monville C, Torres EM, Wong LF, Azzouz M, Mazarakis ND, Dunnett SB (2005) Lentivector mediated delivery of GDNF protects complex motor functions relevant to human Parkinsonism in a rat lesion model. Eur J Neurosci 22:2587-2595
    • (2005) Eur J Neurosci , vol.22 , pp. 2587-2595
    • Dowd, E.1    Monville, C.2    Torres, E.M.3    Wong, L.F.4    Azzouz, M.5    Mazarakis, N.D.6    Dunnett, S.B.7
  • 15
    • 0037418614 scopus 로고    scopus 로고
    • Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease
    • 12628749 10.1016/S0378-4274(02)00428-9 1:CAS:528:DC%2BD3sXhvFeqsrc%3D
    • Eberhardt O, Schulz JB (2003) Apoptotic mechanisms and antiapoptotic therapy in the MPTP model of Parkinson's disease. Toxicol Lett 139:135-151
    • (2003) Toxicol Lett , vol.139 , pp. 135-151
    • Eberhardt, O.1    Schulz, J.B.2
  • 16
    • 0029896966 scopus 로고    scopus 로고
    • Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter
    • 8643547 10.1073/pnas.93.10.5166 1:CAS:528:DyaK28XjtVKlu7k%3D
    • Erickson JD, Schafer MK, Bonner TI, Eiden LE, Weihe E (1996) Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter. Proc Natl Acad Sci 93:5166-5171
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 5166-5171
    • Erickson, J.D.1    Schafer, M.K.2    Bonner, T.I.3    Eiden, L.E.4    Weihe, E.5
  • 17
    • 0030857820 scopus 로고    scopus 로고
    • Melatonin and vitamin e limit nitric oxide induced lipid peroxidation in rat brain homogenates
    • 9272682 10.1016/S0304-3940(97)00498-9 1:CAS:528:DyaK2sXlsVWisLw%3D
    • Escames G, Guerrero JM, Reiter RJ, Garcia JJ, MunozHoyos A, Ortiz GG (1997) Melatonin and vitamin E limit nitric oxide induced lipid peroxidation in rat brain homogenates. Neurosci Lett 230:147-150
    • (1997) Neurosci Lett , vol.230 , pp. 147-150
    • Escames, G.1    Guerrero, J.M.2    Reiter, R.J.3    Garcia, J.J.4    Munozhoyos, A.5    Ortiz, G.G.6
  • 18
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde, and related aldehydes
    • 1937131 10.1016/0891-5849(91)90192-6 1:CAS:528:DyaK3MXmsFSnsbo%3D
    • Esterbauer H, Schaur RJ, Zollner H (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde, and related aldehydes. Free Radic Biol Med 11:81-128
    • (1991) Free Radic Biol Med , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zollner, H.3
  • 19
    • 0022525619 scopus 로고
    • Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse
    • 2430229 10.1016/0028-3908(86)90205-4 1:CAS:528:DyaL28XlslSjsro%3D
    • Ferraro TN, Golden GT, DeMattei M, Hare TA, Fariello RG (1986) Effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on levels of glutathione in the extrapyramidal system of the mouse. Neuropharmacology 25:1071-1074
    • (1986) Neuropharmacology , vol.25 , pp. 1071-1074
    • Ferraro, T.N.1    Golden, G.T.2    Demattei, M.3    Hare, T.A.4    Fariello, R.G.5
  • 20
    • 67049161883 scopus 로고    scopus 로고
    • Strain-specific sensitivity to MPTP of C57BL/6 and BALB/c mice is age dependent
    • 19349914 10.1097/WNR.0b013e32832aa95b 1:CAS:528:DC%2BD1MXltV2hsrc%3D
    • Filipov NM, Norwood AB, Sistrunk SC (2009) Strain-specific sensitivity to MPTP of C57BL/6 and BALB/c mice is age dependent. Neuroreport 20:713-717
    • (2009) Neuroreport , vol.20 , pp. 713-717
    • Filipov, N.M.1    Norwood, A.B.2    Sistrunk, S.C.3
  • 21
    • 0035313071 scopus 로고    scopus 로고
    • Caspase-8 Is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
    • 11264300 1:CAS:528:DC%2BD3MXjslCmu7g%3D
    • Hartmann A, Troadec J, Hunot S, Kikly K, Baptiste A (2001) Caspase-8 Is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. J Neurosci 21:2247-2255
    • (2001) J Neurosci , vol.21 , pp. 2247-2255
    • Hartmann, A.1    Troadec, J.2    Hunot, S.3    Kikly, K.4    Baptiste, A.5
  • 22
    • 38449092831 scopus 로고    scopus 로고
    • Animal models in neurodegenerative diseases
    • Hirsch EC (2007) Animal models in neurodegenerative diseases. J Neural TransmSuppl 87-90
    • (2007) J Neural TransmSuppl , pp. 87-90
    • Hirsch, E.C.1
  • 23
    • 46949110191 scopus 로고    scopus 로고
    • GDNF therapy for Parkinson's disease
    • 18590482 10.1586/14737175.8.7.1125 1:CAS:528:DC%2BD1cXnvFShs7s%3D
    • Hong M, Mukhida K, Mendez I (2008) GDNF therapy for Parkinson's disease. Expert Rev Neurother 8:1125-1139
    • (2008) Expert Rev Neurother , vol.8 , pp. 1125-1139
    • Hong, M.1    Mukhida, K.2    Mendez, I.3
  • 24
    • 0031687793 scopus 로고    scopus 로고
    • Understanding cell death in Parkinson's disease
    • Jenner P, Olanow CW (1998) Understanding cell death in Parkinson's disease. Ann Neurol 44:72-84
    • (1998) Ann Neurol , vol.44 , pp. 72-84
    • Jenner, P.1    Olanow, C.W.2
  • 25
    • 0016151122 scopus 로고
    • Bromobenzene induced liver necrosis: Protective role of glutathione and evidence for 3, 4-bromobenzenoxide as the hepatotoxic intermediate
    • 4831804 10.1159/000136485 1:CAS:528:DyaE2cXkslejtLk%3D
    • Jollow D, Mitchell L, Zampaglione N, Gillete J (1974) Bromobenzene induced liver necrosis: protective role of glutathione and evidence for 3, 4-bromobenzenoxide as the hepatotoxic intermediate. Pharmacology 11:151-169
    • (1974) Pharmacology , vol.11 , pp. 151-169
    • Jollow, D.1    Mitchell, L.2    Zampaglione, N.3    Gillete, J.4
  • 26
    • 77955985008 scopus 로고    scopus 로고
    • Amelioration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced behavioral dysfunction and oxidative stress by Pycnogenol in mouse model of Parkinson's disease
    • 20657266 10.1097/FBP.0b013e32833d4186 1:CAS:528:DC%2BC3cXhtVCntb7I
    • Khan MM, Hoda MN, Ishrat T, Ahmad A, Khan MB, Khuwaja G, Raza SS, Safhi MM, Islam F (2010) Amelioration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced behavioral dysfunction and oxidative stress by Pycnogenol in mouse model of Parkinson's disease. Behav Pharmacol 21:563-571
    • (2010) Behav Pharmacol , vol.21 , pp. 563-571
    • Khan, M.M.1    Hoda, M.N.2    Ishrat, T.3    Ahmad, A.4    Khan, M.B.5    Khuwaja, G.6    Raza, S.S.7    Safhi, M.M.8    Islam, F.9
  • 27
    • 0029812837 scopus 로고    scopus 로고
    • Rat hippocampal neurons express genes for both rod retinal and olfactory cyclic nucleotide gated channels: Novel targets for cAMP/cGMP function
    • 8816819 10.1073/pnas.93.19.10440 1:CAS:528:DyaK28XlslGrsr0%3D
    • Kingston PA, Zufall F, Barnstable CJ (1996) Rat hippocampal neurons express genes for both rod retinal and olfactory cyclic nucleotide gated channels: novel targets for cAMP/cGMP function. Proc Natl Acad Sci 93:10440-10445
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 10440-10445
    • Kingston, P.A.1    Zufall, F.2    Barnstable, C.J.3
  • 28
    • 0034721690 scopus 로고    scopus 로고
    • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease
    • 11052933 10.1126/science.290.5492.767 1:CAS:528:DC%2BD3cXns1akur4%3D
    • Kordower JH, Emborg ME, Bloch J, Ma SY, Chu Y, Leventhal L, McBride J, Chen EY, Palfi S (2000) Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. Science 290:767-773
    • (2000) Science , vol.290 , pp. 767-773
    • Kordower, J.H.1    Emborg, M.E.2    Bloch, J.3    Ma, S.Y.4    Chu, Y.5    Leventhal, L.6    McBride, J.7    Chen, E.Y.8    Palfi, S.9
  • 29
    • 0038171270 scopus 로고    scopus 로고
    • Role of dopamine transporter against MPTP (1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine) neurotoxicity in mice
    • 12822832 10.1023/A:1023863003093 1:CAS:528:DC%2BD3sXjvVagsbs%3D
    • Kurosaki R, Muramatsu Y, Watanabe H, Michimata M, Matsubara M, Imai Y, Araki T (2003) Role of dopamine transporter against MPTP (1-methyl-4-phenyl-1,2, 3,6-tetrahydropyridine) neurotoxicity in mice. Metab Brain Dis 18:139-146
    • (2003) Metab Brain Dis , vol.18 , pp. 139-146
    • Kurosaki, R.1    Muramatsu, Y.2    Watanabe, H.3    Michimata, M.4    Matsubara, M.5    Imai, Y.6    Araki, T.7
  • 30
    • 0032489683 scopus 로고    scopus 로고
    • Topographical distribution of [125I]-glial cell line derived neurotrophic factor in unlesioned and MPTP-lesioned rhesus monkey brain following a bolus intraventricular injection
    • 9602028 10.1016/S0006-8993(97)01495-9 1:CAS:528:DyaK1cXhvFGrtb4%3D
    • Lapchak PA, Araujo DM, Hilt DC, Jiao S, Collin F, Miyoshi Y, Yi A, Zhang Z, Gash DM (1998) Topographical distribution of [125I]-glial cell line derived neurotrophic factor in unlesioned and MPTP-lesioned rhesus monkey brain following a bolus intraventricular injection. Brain Res 789:9-22
    • (1998) Brain Res , vol.789 , pp. 9-22
    • Lapchak, P.A.1    Araujo, D.M.2    Hilt, D.C.3    Jiao, S.4    Collin, F.5    Miyoshi, Y.6    Yi, A.7    Zhang, Z.8    Gash, D.M.9
  • 31
    • 21444451858 scopus 로고    scopus 로고
    • MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contact
    • 15936837 10.1016/j.neures.2005.04.010 1:CAS:528:DC%2BD2MXlvFanu74%3D
    • Lau YS, Novikova L, Roels C (2005) MPTP treatment in mice does not transmit and cause Parkinsonian neurotoxicity in non-treated cagemates through close contact. Neurosci Res 52:371-378
    • (2005) Neurosci Res , vol.52 , pp. 371-378
    • Lau, Y.S.1    Novikova, L.2    Roels, C.3
  • 32
    • 0042326356 scopus 로고    scopus 로고
    • Differential effects of carboxyfullerene on MPP+/MPTP-induced neurotoxicity
    • 12971912 10.1016/S0197-0186(03)00113-X 1:CAS:528:DC%2BD3sXntVGmsr4%3D
    • Lin AM, Yang CH, Ueng YF, Luh TY, Liu TY, Lay YP, Ho LT (2004) Differential effects of carboxyfullerene on MPP+/MPTP-induced neurotoxicity. Neurochem Int 44:99-105
    • (2004) Neurochem Int , vol.44 , pp. 99-105
    • Lin, A.M.1    Yang, C.H.2    Ueng, Y.F.3    Luh, T.Y.4    Liu, T.Y.5    Lay, Y.P.6    Ho, L.T.7
  • 33
    • 0027285510 scopus 로고
    • GDNF: A glial cell line derived neurotrophic factor for midbrain
    • 8493557 10.1126/science.8493557 1:CAS:528:DyaK2cXks1Gguw%3D%3D
    • Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F (1993) GDNF: a glial cell line derived neurotrophic factor for midbrain. Science 260:1130-1132
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 34
    • 0028353974 scopus 로고
    • Neurotrophic factors: From molecule to man
    • 7520198 10.1016/0166-2236(94)90099-X 1:CAS:528:DyaK2cXktVWjsbk%3D
    • Lindsay RM, Wiegand SJ, Altar CA, DiStefano PS (1994) Neurotrophic factors: from molecule to man. Trends Neurosci 17:182-190
    • (1994) Trends Neurosci , vol.17 , pp. 182-190
    • Lindsay, R.M.1    Wiegand, S.J.2    Altar, C.A.3    Distefano, P.S.4
  • 35
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • 14907713 1:CAS:528:DyaG38XhsVyrsw%3D%3D
    • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Biol Chem 193:265-275
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.H.1    Rosebrough, N.J.2    Farr, A.L.3    Randall, R.J.4
  • 36
    • 84875354637 scopus 로고    scopus 로고
    • Geraniol modulates tongue and hepatic phase i and phase II conjugation activities and may contribute directly to the chemopreventive activity against experimental oral carcinogenesis
    • 23499697 10.1016/j.ejphar.2013.02.048 1:CAS:528:DC%2BC3sXmtVantbg%3D
    • Madankumar A, Jayakumar S, Gokuladhas K, Rajan B, Raghunandhakumar S, Asokkumar S, Devaki T (2013) Geraniol modulates tongue and hepatic phase I and phase II conjugation activities and may contribute directly to the chemopreventive activity against experimental oral carcinogenesis. Eur J Pharmacol 705:148-155
    • (2013) Eur J Pharmacol , vol.705 , pp. 148-155
    • Madankumar, A.1    Jayakumar, S.2    Gokuladhas, K.3    Rajan, B.4    Raghunandhakumar, S.5    Asokkumar, S.6    Devaki, T.7
  • 37
    • 0020972417 scopus 로고
    • Glutathione
    • 6137189 10.1146/annurev.bi.52.070183.003431 1:CAS:528:DyaL3sXkvVektbs%3D
    • Meister A, Anderson ME (1983) Glutathione. Annu Rev Biochem 52:711-760
    • (1983) Annu Rev Biochem , vol.52 , pp. 711-760
    • Meister, A.1    Anderson, M.E.2
  • 38
    • 0033597983 scopus 로고    scopus 로고
    • Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease
    • 10454142 10.1016/S0304-3940(99)00463-2 1:CAS:528:DyaK1MXksFait74%3D
    • Mogi M, Togari A, Kondo T, Mizuno Y, Komure O, Kuno S, Ichinose H, Nagatsu T (1999) Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson's disease. Neurosci Lett 270:45-48
    • (1999) Neurosci Lett , vol.270 , pp. 45-48
    • Mogi, M.1    Togari, A.2    Kondo, T.3    Mizuno, Y.4    Komure, O.5    Kuno, S.6    Ichinose, H.7    Nagatsu, T.8
  • 39
    • 70449527787 scopus 로고    scopus 로고
    • Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation
    • 19384567 10.1007/s12640-009-9037-x 1:CAS:528:DC%2BD1MXhtVejurnK
    • Moon M, Kim HG, Hwang L, Seo JH, Kim S, Hwang S, Kim S, Lee D, Chung H, Oh MS, Lee KT, Park S (2009) Neuroprotective effect of ghrelin in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease by blocking microglial activation. Neurotox Res 15:332-347
    • (2009) Neurotox Res , vol.15 , pp. 332-347
    • Moon, M.1    Kim, H.G.2    Hwang, L.3    Seo, J.H.4    Kim, S.5    Hwang, S.6    Kim, S.7    Lee, D.8    Chung, H.9    Oh, M.S.10    Lee, K.T.11    Park, S.12
  • 40
    • 0031801548 scopus 로고    scopus 로고
    • Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity in mice
    • 9657530 1:CAS:528:DyaK1cXktlCrsro%3D
    • Muralikrishnan D, Mohanakumar KP (1998) Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. FASEB J 12:905-912
    • (1998) FASEB J , vol.12 , pp. 905-912
    • Muralikrishnan, D.1    Mohanakumar, K.P.2
  • 41
    • 33847733833 scopus 로고    scopus 로고
    • Levodopa induced hyperactivity in mice treated with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine
    • 17133519 10.1002/mds.21235
    • Nicholas AP (2007) Levodopa induced hyperactivity in mice treated with 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine. Mov Disord 22:99-104
    • (2007) Mov Disord , vol.22 , pp. 99-104
    • Nicholas, A.P.1
  • 42
    • 41249088472 scopus 로고    scopus 로고
    • Treatment of Parkinson's disease with trophic factors
    • 18394569 10.1016/j.nurt.2008.02.003 1:CAS:528:DC%2BD1cXmtFOltbo%3D
    • Peterson AL, Nutt JG (2008) Treatment of Parkinson's disease with trophic factors. Neurotherapeutics 5:270-280
    • (2008) Neurotherapeutics , vol.5 , pp. 270-280
    • Peterson, A.L.1    Nutt, J.G.2
  • 43
    • 10244222286 scopus 로고    scopus 로고
    • MPTP as a mitochondrial neurotoxic model of Parkinson's disease
    • 15377875 10.1023/B:JOBB.0000041771.66775.d5 1:CAS:528: DC%2BD2cXnsFyjtbc%3D
    • Przedborski S, Tieu K, Perier C, Vila M (2004) MPTP as a mitochondrial neurotoxic model of Parkinson's disease. J Bioenerg Biomembr 36:375-379
    • (2004) J Bioenerg Biomembr , vol.36 , pp. 375-379
    • Przedborski, S.1    Tieu, K.2    Perier, C.3    Vila, M.4
  • 44
    • 0029043697 scopus 로고
    • Influence of metabolic inhibitors on mitochondrial permeability transition and glutathione status
    • 7599224 10.1016/0925-4439(95)00008-R
    • Reed DJ, Savage MK (1995) Influence of metabolic inhibitors on mitochondrial permeability transition and glutathione status. Biochim Biophys Acta 1271:43-50
    • (1995) Biochim Biophys Acta , vol.1271 , pp. 43-50
    • Reed, D.J.1    Savage, M.K.2
  • 45
    • 0032168609 scopus 로고    scopus 로고
    • The overall rod performance test in the MPTP-treated mouse model of Parkinsonism
    • 9765130 10.1016/S0165-0270(98)00078-8 1:CAS:528:DyaK1cXmsF2ntbg%3D
    • Rozas G, Lopez-Martin E, Guerra MJ, Labandeira-Garcia JL (1998) The overall rod performance test in the MPTP-treated mouse model of Parkinsonism. J Neurosci Methods 83:165-175
    • (1998) J Neurosci Methods , vol.83 , pp. 165-175
    • Rozas, G.1    Lopez-Martin, E.2    Guerra, M.J.3    Labandeira-Garcia, J.L.4
  • 46
    • 0034528682 scopus 로고    scopus 로고
    • GDNF - A stranger in the TGF-beta superfamily?
    • 11106404 10.1046/j.1432-1327.2000.01826.x 1:CAS:528: DC%2BD3MXis1Kntw%3D%3D
    • Saarma M (2000) GDNF - a stranger in the TGF-beta superfamily? Eur J Biochem 267:6968-6971
    • (2000) Eur J Biochem , vol.267 , pp. 6968-6971
    • Saarma, M.1
  • 47
    • 0035003439 scopus 로고    scopus 로고
    • Chemistry and biochemistry of oxidative stress in neurodegenerative disease
    • 11375746 10.2174/0929867013372922 1:CAS:528:DC%2BD3MXjsVChtbs%3D
    • Sayre LM, Smith MA, Perry G (2001) Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem 8:721-738
    • (2001) Curr Med Chem , vol.8 , pp. 721-738
    • Sayre, L.M.1    Smith, M.A.2    Perry, G.3
  • 48
    • 5544229693 scopus 로고    scopus 로고
    • Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP
    • 15503155 10.1007/s00441-004-0938-y
    • Schober A (2004) Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP. Cell Tissue Res 318:215-224
    • (2004) Cell Tissue Res , vol.318 , pp. 215-224
    • Schober, A.1
  • 49
    • 0025879020 scopus 로고
    • Relationships between indices of behavioral asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injections
    • 1933318 10.1016/0006-8993(91)90170-Z 1:CAS:528:DyaK3MXltlegsrc%3D
    • Schwarting RK, Bonatz AE, Carey RJ, Huston JP (1991) Relationships between indices of behavioral asymmetries and neurochemical changes following mesencephalic 6-hydroxydopamine injections. Brain Res 554:46-55
    • (1991) Brain Res , vol.554 , pp. 46-55
    • Schwarting, R.K.1    Bonatz, A.E.2    Carey, R.J.3    Huston, J.P.4
  • 50
    • 0030272769 scopus 로고    scopus 로고
    • The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery, and treatments
    • 8971983 10.1016/S0301-0082(96)00040-8 1:CAS:528:DyaK2sXks12hsQ%3D%3D
    • Schwarting RK, Huston JP (1996) The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery, and treatments. Prog Neurobiol 50:275-331
    • (1996) Prog Neurobiol , vol.50 , pp. 275-331
    • Schwarting, R.K.1    Huston, J.P.2
  • 51
    • 15744401358 scopus 로고    scopus 로고
    • The MPTP model of Parkinson's disease
    • 15790530 10.1016/j.molbrainres.2004.09.017 1:CAS:528:DC%2BD2MXisFGmu70%3D
    • Smeyne RJ, Jackson-Lewis V (2005) The MPTP model of Parkinson's disease. Brain Res Mol Brain Res 134:57-66
    • (2005) Brain Res Mol Brain Res , vol.134 , pp. 57-66
    • Smeyne, R.J.1    Jackson-Lewis, V.2
  • 53
    • 0025118725 scopus 로고
    • Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: A model for Parkinson's disease
    • 2271921 10.1016/0006-8993(90)91656-2 1:STN:280:DyaK3M7gsFClug%3D%3D
    • Sundstrom E, Fredriksson A, Archer T (1990) Chronic neurochemical and behavioral changes in MPTP-lesioned C57BL/6 mice: a model for Parkinson's disease. Brain Res 528:181-188
    • (1990) Brain Res , vol.528 , pp. 181-188
    • Sundstrom, E.1    Fredriksson, A.2    Archer, T.3
  • 54
    • 35348966882 scopus 로고    scopus 로고
    • Neuroinflammatory mechanisms in Parkinson's disease: Potential environmental triggers, pathways, and targets for early therapeutic intervention
    • ansey MG, McCoy MK, Frank-Cannon TC (2007) Neuroinflammatory mechanisms in Parkinson's disease: potential environmental triggers, pathways, and targets for early therapeutic intervention. Exp Neurol 208:1-25
    • (2007) Exp Neurol , vol.208 , pp. 1-25
    • Ansey, M.G.1    McCoy, M.K.2    Frank-Cannon, T.C.3
  • 55
    • 0036447089 scopus 로고    scopus 로고
    • Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine
    • 12460610 10.1006/exnr.2002.8021 1:CAS:528:DC%2BD38XovVygsLc%3D
    • Tillerson JL, Caudle WM, Reveron ME, Miller GW (2002) Detection of behavioral impairments correlated to neurochemical deficits in mice treated with moderate doses of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Exp Neurol 178:80-90
    • (2002) Exp Neurol , vol.178 , pp. 80-90
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 56
    • 59249105539 scopus 로고    scopus 로고
    • Plant-derived antioxidants geraniol and camphene protect rat alveolar macrophages against t-BHP-induced oxidative stress
    • 19135518 10.1016/j.tiv.2008.12.014 1:CAS:528:DC%2BD1MXhs1ejtro%3D
    • Tiwari M, Kakkar P (2009) Plant-derived antioxidants geraniol and camphene protect rat alveolar macrophages against t-BHP-induced oxidative stress. Toxicol In Vitro 23:295-301
    • (2009) Toxicol in Vitro , vol.23 , pp. 295-301
    • Tiwari, M.1    Kakkar, P.2
  • 57
    • 80755153266 scopus 로고    scopus 로고
    • Preventive and therapeutic effects of caffeic acid against inflammatory injury in striatum of MPTP-treated mice
    • 21970803 10.1016/j.ejphar.2011.09.171 1:CAS:528:DC%2BC3MXhsVaqtrrE
    • Tsai S, Chao C, Yin M (2011) Preventive and therapeutic effects of caffeic acid against inflammatory injury in striatum of MPTP-treated mice. Eur J Pharmacol 670:441-447
    • (2011) Eur J Pharmacol , vol.670 , pp. 441-447
    • Tsai, S.1    Chao, C.2    Yin, M.3
  • 58
    • 43649104203 scopus 로고    scopus 로고
    • Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced Parkinsonism
    • 18413287 10.1016/j.nbd.2008.02.011 1:CAS:528:DC%2BD1cXmtlShs7s%3D
    • Viaro R, Sanchez-Pernaute R, Marti M, Trapella C, Isacson O, Morari M (2008) Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced Parkinsonism. Neurobiol Dis 30:430-438
    • (2008) Neurobiol Dis , vol.30 , pp. 430-438
    • Viaro, R.1    Sanchez-Pernaute, R.2    Marti, M.3    Trapella, C.4    Isacson, O.5    Morari, M.6
  • 60
    • 0033668692 scopus 로고    scopus 로고
    • Chemical neuroanatomy of the vesicular amine transporters
    • 11099461 10.1096/fj.00-0202rev 1:CAS:528:DC%2BD3MXht1Snt7o%3D
    • Weihe E, Eiden LE (2000) Chemical neuroanatomy of the vesicular amine transporters. FASEB J 14:2435-2449
    • (2000) FASEB J , vol.14 , pp. 2435-2449
    • Weihe, E.1    Eiden, L.E.2
  • 61
    • 0032579840 scopus 로고    scopus 로고
    • Effects of haloperidol metabolites on neurotransmitter uptake and release: Possible role in neurotoxicity and tardive dyskinesia
    • 9555021 10.1016/S0006-8993(97)01551-5 1:CAS:528:DyaK1cXhvVSisr0%3D
    • Wright AM, Bempong J, Kirby ML, Barlow RL, Bloomquist JR (1998) Effects of haloperidol metabolites on neurotransmitter uptake and release: possible role in neurotoxicity and tardive dyskinesia. Brain Res 788:215-222
    • (1998) Brain Res , vol.788 , pp. 215-222
    • Wright, A.M.1    Bempong, J.2    Kirby, M.L.3    Barlow, R.L.4    Bloomquist, J.R.5
  • 62
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's Disease
    • 11880505 1:CAS:528:DC%2BD38XhvValtbo%3D
    • Wu DC, Jackson-Lewis V, Vila M, Tieu K, Teismann P, Vadseth C, Choi DK, Ischiropoulos H, Przedborski S (2002) Blockade of microglial activation is neuroprotective in the1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's Disease. J Neurosci 22:1763-1771
    • (2002) J Neurosci , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, P.5    Vadseth, C.6    Choi, D.K.7    Ischiropoulos, H.8    Przedborski, S.9
  • 63
    • 24944582908 scopus 로고    scopus 로고
    • Treatment of Parkinson's disease - What's on the horizon?
    • 16142989 10.2165/00023210-200519090-00001 1:CAS:528:DC%2BD2MXhtFWrtr%2FK
    • Wu SS, Frucht SJ (2005) Treatment of Parkinson's disease - what's on the horizon? CNS Drugs 19:723-743
    • (2005) CNS Drugs , vol.19 , pp. 723-743
    • Wu, S.S.1    Frucht, S.J.2
  • 64
    • 77950368837 scopus 로고    scopus 로고
    • Catalpol attenuates MPTP-induced neuronal degeneration of niagral striatal dopaminergic pathway in mice through elevating glial cell derived neurotropic factor in striatum
    • 20123001 10.1016/j.neuroscience.2010.01.048 1:CAS:528: DC%2BC3cXjt1els70%3D
    • Xu G, Xiongy Z, Yong Y, Wang Z, Ke Z, Xia Z, Hu Y (2010) Catalpol attenuates MPTP-induced neuronal degeneration of niagral striatal dopaminergic pathway in mice through elevating glial cell derived neurotropic factor in striatum. Neuroscience 167:174-184
    • (2010) Neuroscience , vol.167 , pp. 174-184
    • Xu, G.1    Xiongy, Z.2    Yong, Y.3    Wang, Z.4    Ke, Z.5    Xia, Z.6    Hu, Y.7
  • 65
    • 72449188768 scopus 로고    scopus 로고
    • Reversible neurochemical changes mediated by delayed intrastriatal glial cell line derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model
    • 19639608 10.1002/jgm.1377 1:CAS:528:DC%2BD1MXhtlyqurvN
    • Yang X, Mertens B, Lehtonen E, Vercammen L, Bockstael O, Chtarto A, Levivier M, Brotchi J, Michotte Y, Baekelandt V, Sarre S, Tenenbaum L (2009) Reversible neurochemical changes mediated by delayed intrastriatal glial cell line derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model. J Gene Med 11:899-912
    • (2009) J Gene Med , vol.11 , pp. 899-912
    • Yang, X.1    Mertens, B.2    Lehtonen, E.3    Vercammen, L.4    Bockstael, O.5    Chtarto, A.6    Levivier, M.7    Brotchi, J.8    Michotte, Y.9    Baekelandt, V.10    Sarre, S.11    Tenenbaum, L.12
  • 66
    • 54349089328 scopus 로고    scopus 로고
    • The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains
    • 18817984 10.1016/j.jneuroim.2008.08.003 1:CAS:528:DC%2BD1cXhtlartb7I
    • Yasuda Y, Shimoda T, Uno K, Tateishi N, Furuya S, Yagi K (2008) The effects of MPTP on the activation of microglia/astrocytes and cytokine/chemokine levels in different mice strains. J Neuroimmunol 204:43-51
    • (2008) J Neuroimmunol , vol.204 , pp. 43-51
    • Yasuda, Y.1    Shimoda, T.2    Uno, K.3    Tateishi, N.4    Furuya, S.5    Yagi, K.6
  • 67
    • 0035830696 scopus 로고    scopus 로고
    • Differential expression of GDNF, BDNF, and NT-3 in the aging nigrostriatal system following a neurotoxic lesion
    • 11164827 10.1016/S0006-8993(00)03217-0 1:CAS:528:DC%2BD3MXnsVGltw%3D%3D
    • Yurek DM, Fletcher-Turner A (2001) Differential expression of GDNF, BDNF, and NT-3 in the aging nigrostriatal system following a neurotoxic lesion. Brain Res 891:228-235
    • (2001) Brain Res , vol.891 , pp. 228-235
    • Yurek, D.M.1    Fletcher-Turner, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.