Impacts of chemical enhancers on skin permeation and deposition of terbinafine

Pharmaceutical Development and Technology

Volumn 19, Issue 5, 2014, Pages 565-570

  Erdal, Meryem Sedef ^a   Peköz, Ayca Yildiz ^a   Aksu, Buket ^b   Araman, Ahmet ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b Santa Farma Drug Company   (Turkey)

Author keywords

ATR FTIR spectroscopy; Penetration enhancer; Tape stripping; Terbinafine; Terpenes; Urea

Indexed keywords

CARBOPOL 934; LIMONENE; NEROLIDOL; PENETRATION ENHANCING AGENT; TERBINAFINE; UREA;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG PENETRATION; EPIDERMIS; EX VIVO STUDY; GEL; INFRARED SPECTROSCOPY; LIPID BILAYER; MYCOSIS; NONHUMAN; PRIORITY JOURNAL; SKIN INFECTION; SKIN PERMEABILITY; STRATUM CORNEUM; SWINE;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIFUNGAL AGENTS; CYCLOHEXENES; NAPHTHALENES; PERMEABILITY; PHARMACEUTICAL VEHICLES; SESQUITERPENES; SKIN; SKIN ABSORPTION; SWINE; TERPENES; UREA;

EID: 84885939265     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2013.813538     Document Type: Article

References (47)

1. Gupta AK, Albreski D, Del Rosso JQ, Konnikov N. The use of the new oral antifungal agents, itraconazole, terbinafine, and fluconazole, to treat onychomycosis and other dermatomycoses. Curr Prob Dermatol 2001;4:220-246.
2. Alberti I, Kalia YN, Naik A, et al. Effect of ethanol and isopropyl myristate on the availability of topical terbinafine in human stratum corneum, in vivo. Int J Pharm 2001;219:11-19.
3. Sachdeva V, Siddoju S, Yu YY, et al. Transdermal iontophoretic delivery of terbinafine hydrochloride: quantitation of drug levels in stratum corneum and underlying skin. Int J Pharm 2010;388:24-31.
4. Özcan I, Abaci Ö , Uztan AH, et al. Enhanced topical delivery of terbinafine with chitosan hydrogels. AAPS Pharm Sci Tech 2009;10: 1024-1031.
5. Vejnovic I, Huonder C, Betz G. Permeation studies of novel terbinafine formulations containing hydrophobins through human nails in vitro. Int J Pharm 2010;397:67-76.
6. Chen YC, Liu DZ, Liu JJ, et al. Development of terbinafine solid lipid nanoparticles as a topical delivery system. Int J Nanomed 2012; 7:4409-4418.
7. Trommer H, Neubert RHH. Overcoming the stratum corneum: the modulation of skin penetration. Skin Pharmacol Physiol 2006;19: 106-121.
8. Hadgraft J. Modulation of the barrier function of the skin. Skin Pharmacol Appl Skin Physiol 2001;14:72-81.
9. Lusiana SR, Müller Goymann CC. Infected nail plate model made of human hair keratin for evaluating the efficacy of different topical antifungal formulations against trichophyton rubrum in vitro. Eur J Pharm Biopharm 2013;84:599-605.
10. Evenbratt H, Fargemann J. Effect of pentane-1,5-diol and propane- 1,2-diol on percutaneous absorption of terbinafine. Acta Derm Venereol 2009;89:126-129.
11. Gao S, Singh J. Effect of oleic acid/ethanol and oleic acid/propylene glycol on the in vitro percutaneous absorption of 5-fluorouracil and tamoxifen and the macroscopic barrier property of porcine epidermis. Int J Pharm 1998;165:45-55.
12. Otto A, Wiechers JW, Kelly CL, et al. Effect of penetration modifiers on the dermal and transdermal delivery of drugs and cosmetic active ingredients. Skin Pharmacol Physiol 2008;21: 326-334.
13. Tanojo H, Junginger HE, Bodde HE. In vivo human skin permeability enhancement by oleic acid: transepidermal water loss and fourier transform infrared spectroscopy studies. J Control Rel 1997; 47:31-39.
14. Escobar Chavez JJ, Quintanar-Guerrero D, Ganem-Quintanar A. In vivo skin permeation of sodium naproxen formulated in pluronic F-127 gels: effect of azone and transcutol. Drug Dev Ind Pharm 2005;31:447-454.
15. Guillard EC, Tfayli A, Laugel C, Baillet-Guffroy A. Molecular interactions of penetration enhancers within ceramides organization: a FTIR approach. Eur J Pharm Sci 2009;36:192-199.
16. Cal K, Kupiec K, Sznitowska M. Effect of physicochemical properties of cyclic terpenes on their ex vivo skin absorption and elimination kinetics. J Dermatol Sci 2006;41:137-142.
17. Cal K. Skin disposition of menthol after its application in the presence of drug substances. Biopharm Drug Dispos 2008;29: 449-454.
18. Klang V, Schwarz JC, Haberfeld S, et al. Skin integrity testing and monitoring of in vitro tape stripping by capacitance-based sensor imaging. Skin Res Technol 2012;1:1-14.
19. Hathout RM, ve Elshafeey AH. Development and characterization of colloidal soft nanocarriers for transdermal delivery and bioavailability enhancement of an angiotensin II receptor blocker. Eur J Pharm Biopharm 2012;82:230-240.
20. El-Kattan AF, Asbill CS, Kim N, Michniak BB. The effects of terpene enhancers on the percutaneous permeation of drugs with different lipophilicities. Int J Pharm 2001;215:229-240.
21. Güngör S, Bektaş A, Alp FI, et al. Matrix type transdermal patches of verapamil hydrochloride: in vitro permeation studies through excised rat skin and pharmacodynamic evaluation in rats. Pharm Dev Technol 2008;13:283-289.
22. Ahad A, Aqil M, Kohli K, et al. Role of novel terpenes in transcutaneous permeation of valsartan: effectiveness and mechanism of action. Drug Dev Ind Pharm 2011;37:583-596.
23. Cornwell PA, Barry BW. Sesquiterpene components of volatile oils as skin penetration enhancers for the hydrophilic permeant 5-fluorouracil. J Pharm Pharmacol 1994;46:261-269.
24. Godwin DA, Michniak BB. Influence of drug lipophilicity on terpenes as transdermal penetration enhancers. Drug Dev Ind Pharm 1999;25:905-915.
25. Krishnaiah YSR, Raju V, Kumar MS, et al. Studies on optimizing in vitro transdermal permeation of ondansetron hydrochloride using nerolidol, carvone, and limonene as penetration enhancers. Pharm Dev Technol 2008;13:177-185.
26. Ota Y, Hamada A, Nakano M, Saito H. Evaluation of percutaneous absorption of midazolam by terpenes. Drug Metab Pharmacokin 2003;18:261-266.
27. Levison KK, Takayama K, Isowa K, et al. Formulation optimization of indomethacin gels containing a combination of three kinds of cyclic monoterpenes as percutaneous penetration enhancers. J Pharm Sci 1994;83:1367-1372.
28. Zhao K, Singh J. Mechanisms of percutaneous absorption of tamoxifen by terpenes: eugenol, d-limonene and menthone. J Control Rel 1998;55:253-260.
29. Şenyigit T, Padula C, Özer Ö , Santi P. Different approaches for improving skin accumulation of topical corticosteroids. Int J Pharm 2009;380:155-160.
30. Aqil M, Ahad A, Sultana Y, Ali A. Status of terpenes as skin penetration enhancers. Drug Discovery Today 2007;12:1061-1067.
31. Fang JY, Hwang TL, Leu YL. Effect of enhancers and retarders on percutaneous absorption of flurbiprofen from hydrogels. Int J Pharm 2003;250:313-325.
32. Panchagnula R, Desu H, Jain A, Khandavilli S. Effect of lipid bilayer alteration on transdermal delivery of a high molecular weight and lipophilic drug: studies with paclitaxel. J Pharm Sci 2004;93: 2177-2183.
33. Gonçalves do Couto S, Oliveir MS, Alonso A. Dynamics of proteins and lipids in the stratum corneum: effects of percutaneous permeation enhancers. Biophysical Chem 2005;116:23-31.
34. Zbytovska J, Vavrova K, Kiselev MA, et al. The effects of transdermal penetration enhancers on thermotropic phase behavior of a stratum corneum lipid model. Colloids Surf A Physicochem Eng Aspects 2009;351:30-37.
35. Godwin DA, Player MR, Sowell JW, Michniak BB. Synthesis and investigation of urea compounds as transdermal penetration enhancers. Int J Pharm 1998;167:165-175.
36. Pelchrzim Rv, Weigmann HJ, Schaefer H, et al. Determination of the formation of the stratum corneum reservoir for two different corticosteroid formulations using tape stripping combined with UV/VIS spectroscopy. J Dtsch Dermatol Ges 2004;2:914-919.
37. Bolzinger MA, Brinçon S, Pelletier J, Chevalier Y. Penetration of drugs through skin, a complex rate controlling membrane. Curr Opin Colloid Interface Sci 2012;17:156-165.
38. Herkenne C, Alberti I, Naik A, et al. In vivo methods for the assessment of topical drug bioavailability. Pharm Res 2008;25: 87-103.
39. Gorcea M, Hadgraft J, Moore DJ, Lane ME. In vivo barrier challenge and initial recovery in human facial skin. Skin Res Technol 2013;19:e375-e382.
40. Obata Y, Utsumi S, Watanabe H, et al. Infrared spectroscopic study of lipid interaction in stratum corneum treated with transdermal absorption enhancers. Int J Pharm 2010;389:18-23.
41. Takahashi K, Sakano H, Yoshida M, et al. Characterization of the influence of polyol fatty acid esters on the permeation of diclofenac through rat skin. J Control Rel 2001;73:351-358.
42. Schwarz JC, Klang V, Hoppel M, et al. Natural microemulsions: formulation design and skin interaction. Eur J Pharm Biopharm 2012;81:557-562.
43. Williams AC, Walters KA. Chemical penetration enhancement: possibilities and problems. In: Walters KA, Roberts MS, eds. Dermatologic, cosmeceutic, and cosmetic development. NY: Informa Healthcare Inc USA; 2008:497-504.
44. Laugel C, Yagoubi N, Baillet A. ATR-FTIR spectroscopy: a chemometric approach for studying the lipid organization of the stratum corneum. Chem Phys Lipids 2005;135:55-68.
45. Ibrahim SA, Li SK. Chemical enhancer solubility in human stratum corneum lipids and enhancer mechanism of action on stratum corneum lipid domain. Int J Pharm 2010;383:89-98.
46. Babita K, Kumar V, Rana V, et al. Thermotropic and spectroscopic behavior of skin: relationship with percutaneous penetration enhancement. Current Drug Deliv 2006;3:95-113.
47. Williams AC, Barry BW. Terpenes and the lipid-proteinpartitioning theory of skin penetration enhancement. Pharm Res 1991;1:17-24.