Development and characterization of colloidal soft nano-carriers for transdermal delivery and bioavailability enhancement of an angiotensin II receptor blocker

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 2, 2012, Pages 230-240

  Hathout, Rania M ^a   Elshafeey, Ahmed H ^b  

^a Ain Shams University   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Human volunteers; Infrared spectroscopy; Microemulsion; Olmesartan; Skin permeation; Tape stripping

Indexed keywords

DIETHYLENE GLYCOL MONOETHYL ETHER; LABRASOL; NANOCARRIER; OIL; OLEIC ACID; OLMESARTAN; WATER;

ADULT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CHEMICAL STRUCTURE; COLLOID; CONFORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG ELIMINATION; DRUG FORMULATION; DRUG HALF LIFE; ELECTRIC CONDUCTIVITY; EX VIVO STUDY; HUMAN; HUMAN EXPERIMENT; INFRARED SPECTROSCOPY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MICROEMULSION; NONHUMAN; NORMAL HUMAN; PH; PHOTON CORRELATION SPECTROSCOPY; PHYSICAL CHEMISTRY; POLARIZATION MICROSCOPE; SINGLE DRUG DOSE; SKIN PERMEABILITY; SPECTROSCOPY; STRATUM CORNEUM; SWINE; TABLET FORMULATION; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, CUTANEOUS; ANGIOTENSIN RECEPTOR ANTAGONISTS; ANIMALS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; COLLOIDS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EMULSIONS; HUMANS; HYDROGEN-ION CONCENTRATION; IMIDAZOLES; NANOPARTICLES; PARTICLE SIZE; SKIN; SOLUBILITY; SWINE; TABLETS; TETRAZOLES;

EID: 84867890639     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.07.002     Document Type: Article

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