In vivo human skin permeability enhancement by oleic acid: Transepidermal water loss and Fourier-transform infrared spectroscopy studies

Journal of Controlled Release

Volumn 47, Issue 1, 1997, Pages 31-39

  Tanojo, Hanafi ^a   Junginger, Hans E ^a   Boddé, Harry E ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Fourier transform infrared spectroscopy; In vivo study; Oleic acid; Skin permeation enhancement; Transepidermal water loss

Indexed keywords

OLEIC ACID; PENETRATION ENHANCING AGENT; PROPYLENE GLYCOL; SKIN LIPID;

ADULT; ARTICLE; DRUG MECHANISM; FEMALE; FOURIER TRANSFORMATION; HUMAN; HUMAN EXPERIMENT; INFRARED SPECTROSCOPY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; SKIN PERMEABILITY; SKIN WATER LOSS; TOPICAL DRUG ADMINISTRATION;

EID: 0030937460     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(96)01613-6     Document Type: Article

References (44)

1. J.E. Shaw and J. Urquhart, Transdermal drug administration - a nuisance becomes an opportunity. Br. Med. J. 283 (1981) 875-876.
2. J. Hadgraft and R.H. Guy, Transdermal Drug Delivery. Developmental Issues and Research Initiatives. New York, Marcel Dekker, 1989.
3. E.R. Cooper, Increased skin permeability for lipophilic molecules. J. Pharm. Sci. 73 (1984) 1153-1156.
4. B.J. Aungst, N.J. Rogers and E. Shefter, Enhancement of naloxone penetration through human skin in vitro using fatty acids, fatty alcohols, surfactants, sulfoxides and amides. Int. J. Pharm. 33 (1986) 225-234.
5. B.W. Barry and S.L. Bennett, Effect of penetration enhancers on the penetration of mannitol, hydrocortisone and progesterone through human skin. J. Pharm. Pharmacol. 39 (1987) 535-546.
6. P.G. Green, R.H. Guy and J. Hadgraft, In vitro and in vivo enhancement of skin permeation with oleic and lauric acids. Int. J. Pharm. 48 (1988) 103-111.
7. T. Loftsson, G. Somogyi and N. Bodor, Effect of choline esters and oleic acid on the penetration of acyclovir, estradiol, hydrocortisone, nitroglycerin, retinoic acid and trifluorothymidine across hairless mouse skin in vitro. Acta Pharm. Nord, 1 (1989) 279-286.
8. M.A. Lampe, A.L. Burlingame, J.A. Whitney, M.L. Williams, B.E. Brown, E. Roitman and P.M. Elias, Human stratum corneum lipids: characterization and regional variations. J. Lipid Res. 24 (1983) 120-130.
9. A.P.M. Lavrijsen, E. Oestmann, J. Hermans, H.E. Boddé, B.J. Vermeer and M. Ponec, Barrier function parameters in various keratinization disorders: transepidermal water loss and vascular response to hexyl nicotinate. Br. J. Dermatol. 129 (1993) 547-554.
10. J. Pinnagoda (1990) Transepidermal Water Loss. Its Role in the Assessment of Susceptibility to the Development of Irritant Contact Dermatitis, Ph.D. Thesis. London, University of London, Faculty of Medicine.
11. T. Winsor and G.E. Burch, Differential roles of layers of human epigastric skin on diffusion rate of water. Arch. Int. Med. 74 (1944) 428-436.
12. I.H. Blank, Factors which influence the water content of the stratum corneum. J. Invest. Dermatol. 18 (1952) 433-440.
13. A.M. Kligman, The biology of the stratum corneum. In: W. Montagna and W.C.J. Lobitz (Eds.), The Epidermis, New York, Academic Press, 1964, pp. 387-433.
14. J. Pinnagoda, R.A. Tupker, P.J. Coenraads and J.P. Nater, Comparability and reproducibility of the results of water loss measurements: a study of 4 evaporimeters. Contact Dermatitis 20 (1989) 241-246.
15. P.G.M. van der Valk, J.P. Nater and E. Bleumink, Skin irritancy of surfactants as assessed by water vapour loss measurements. J. Invest. Dermatol. 82 (1984) 291-293.
16. T. Agner, Basal transepidermal water loss, skin thickness, skin blood flow and skin colour in relation to sodium-lauryl-sulphate-induced irritation in normal skin. Contact Dermatitis 25 (1991) 108-114.
17. H.H. Mantsch, Fourier transform infrared spectroscopy as a probe of biomembrane structure. In: C. Sandorfy and T. Theophanides (Eds.). Spectroscopy of Biological Molecules. Dordrecht, D. Reidel, 1984, pp. 547-561.
18. D.G. Cameron, A. Marin, D.J. Moffatt and H.H. Mantsch, Infrared spectroscopic study of the gel to liquid-crystal phase transition in live Acholeplasma laidlawii cells. Biochemistry 24 (1985) 4355-4359.
19. N.A. Puttnam, Attenuated total reflectance studies on skin. J. Soc. Cosmet. Chem. 23 (1979) 209-226.
20. D. Bommannan, R.O. Potts and R.H. Guy, Examination of stratum corneum barrier function in vivo by infrared spectroscopy. J. Invest. Dermatol. 95 (1990) 403-408.
21. H.E. Boddé, L.A.R.M. Pechtold and F.H.N. de Haan, A large scale, non invasive in vivo screening of the human skin barrier recording ATR-FTIR spectra, TEWL, skin impedance and temperature. Proceed. Int. Symp. Control. Release Bioact. Mater. 18 (1991) 409.
22. V.H.W. Mak, R.O. Potts and R.H. Guy, Oleic acid concentration and effect in human stratum corneum: non-invasive determination by attenuated total reflectance infrared spectroscopy in vivo. J. Control. Release 12 (1990) 67-75.
23. Y. Takeuchi, H. Yasukawa, Y. Yamaoka, N. Takahashi, C. Tamura, Y. Morimoto, S. Fukushima and R.C. Vasavada, Effects of oleic acid/propylene glycol on rat abdominal stratum corneum: lipid extraction and appearance of propylene glycol in the dermis measured by Fourier transform infrared/attenuated total reflectance (FT-IR/ATR) spectroscopy. Chem. Pharm. Bull. 41 (1993) 1434-1437.
24. A. Naik, L.A.R.M. Pechtold, R.O. Potts and R.H. Guy, Mechanism of oleic acid-induced skin penetration enhancement in vivo in humans. J. Control. Release 37 (1995) 299-306.
25. G.E. Nilsson, Measurement of water exchange through skin. Med. Biol. Eng. Comput. 15 (1977) 209-218.
26. J. Pinnagoda, R.A. Tupker, T. Agner and J. Serup, Guidelines for transepidermal water loss (TEWL) measurement. A report from the standardization group of the European Society of Contact Dermatitis. Contact Dermatitis 22 (1990) 164-178.
27. H. Tanojo, J.A. Bouwstra, H.E. Junginger and H.E. Boddé, Effects of oleic acid on human transepidermal water loss using ethanol or propylene glycol as vehicles. In: K.R. Brain, V.J. James and K.A. Walters (Eds.), Prediction of Percutaneous Penetration, Vol. 3b, STS, Cardiff, 1993, pp. 319-324.
28. B.M. Morrison, ServoMed evaporimeter: precautions when evaluating the effect of skin care products on barrier function. J. Soc. Cosmet. Chem. 43 (1992) 161-167.
29. C.W. Blichmann and J. Serup, Reproducibility and variability of transepidermal water loss measurement. Studies on the Servo Med evaporimeter. Acta Derm.-Venereol. 67 (1987) 206-210.
30. E. Oestmann, A.P.M. Lavrijsen, J. Hermans and M. Ponec, Skin barrier function in healthy volunteers as assessed by transepidermal water loss and vascular response to hexyl nicotinate: intra- and inter-individual variability. Br. J. Dermatol. 128 (1993) 130-136.
31. A. Hoelgaard, B. Mollgaard and E. Baker, Vehicle effect on topical drug delivery. IV. Effect of N-methylpyrrolidone and polar lipids on percutaneous drug transport. Int. J. Pharm. 43 (1988) 233-240.
32. R.A. Tupker (1990) The Influence of Detergents on the Human Skin. A Study on Factors Determining the Individual Susceptibility Assessed by Transepidermal Water Loss, Ph.D. Thesis, Groningen, State University Groningen.
33. T. Loftsson, N. Gildersleeve and N. Bodor, The effect of vehicle additives on the transdermal delivery of nitroglycerin. Pharm. Res. 4 (1987) 436-437.
34. E. Boelsma, H. Tanojo, H.E. Boddé and M. Ponec, Assessment of potential irritancy of oleic acid on human skin: Evaluation in vitro and in vivo. Toxic. In Vitro (1997) in press.
35. H.M. Evans and S. Lepkovsky, Vital need of the body for certain unsaturated fatty acids. II. Experiments with high fat diets in which saturated fatty acids furnish the sole source of energy. J. Biol. Chem. 96 (1932) 157-164.
36. G.O. Burr, M.M. Burr and E.S. Miller, On the fatty acids essential in nutrition. III. J. Biol. Chem. 97 (1932) 1-9.
37. R.B. Alfin-Slater, L. Aftergood, A.F. Wells and H.J. Deuel Jr., The effect of essential fatty acid deficiency on the distribution of endogenous cholesterol in the plasma and liver of the rat. Arch. Biochem. Biophys. 52 (1954) 180-185.
38. G.M. Golden, J.E. McKie and R.O. Potts, Role of stratum corneum lipid fluidity in transdermal drug flux. J. Pharm. Sci. 76 (1987) 25-28.
39. M. Walker, D.A. Hollingsbee, J. Hadgraft, L. Monger, G. Martin and C. Marriott, Influence of oleic acid on the physical and chemical properties of human epidermal barrier. In: R.C. Scott, R.H. Guy, J. Hadgraft and H.E. Boddé (Eds.), Prediction of Percutaneous Penetration. Methods, Measurements, Modelling, Vol. 2, London, IBC Technical Services, 1991, pp. 86-96.
40. R.H. Guy, V.H.W. Mak, T. Kai, D. Bommannan and R.O. Potts, Percutaneous penetration enhancers - mode of action. In: R.C. Scott and R.H. Guy (Eds.), Prediction of Percutaneous Penetration - Methods, Measurements, Modelling, IBC Technical Services, London, 1990, pp. 213-223.
41. C.L. Gay, J. Hadgraft, I.W. Kellaway, J.C. Evans and C.C. Rowlands, The effect of skin penetration enhancers on human stratum corneum lipids - an electric spin resonance study. In: R.C. Scott and R.H. Guy (Eds.), Prediction of Percutaneous Penetration - Methods, Measurements, Modelling, IBC Technical Services, London, 1990, pp. 322332.
42. B. Ongpipattanakul, R.R. Burnette, R.O. Potts and M.L. Francoeur, Evidence that oleic acid exists in a separate phase within stratum corneum lipids. Pharm. Res. 8 (1991) 350-354.
43. M. Walker and J. Hadgraft, Oleic acid - a membrane 'fluidizer' or fluid within the membrane? Int. J. Pharm. 71 (1991) R1-R4.
44. K. Knutson, R.O. Potts, D.B. Guzek, G.M. Golden, J.E. McKie, W.J. Lambert and W.I. Higuchi, Macro- and molecular physical-chemical considerations in understanding drug transport in the stratum corneum. J. Control. Release 2 (1985) 67-87.