Androgen glucuronides analysis by liquid chromatography tandem-mass spectrometry: Could it raise new perspectives in the diagnostic field of hormone-dependent malignancies?

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 940, Issue , 2013, Pages 24-34

  Kalogera, Eleni ^a   Pistos, Constantinos ^b   Provatopoulou, Xeni ^a   Athanaselis, Sotirios ^b   Spiliopoulou, Chara ^b   Gounaris, Antonia ^a  

^a Hellenic Anticancer Institute   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Androgen glucuronides; Hormone dependent malignancies; Liquid chromatography; Mass spectrometry; Quantitative analysis; Review

Indexed keywords

DIRECT IMMUNOASSAY; GLUCURONIDES; HORMONE-DEPENDENT MALIGNANCIES; HUMAN PATHOLOGIES; LOW CONCENTRATIONS; MINIMALLY INVASIVE; TANDEM-MASS SPECTROMETRY; TECHNICAL ADVANCES;

BIOACTIVITY; BLOOD; CHEMICAL ANALYSIS; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOLOGY; LIPIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; REVIEWS; TISSUE;

STEROID HORMONES;

ANDROGEN; ANDROGEN GLUCURONIDE; ANDROSTENEDIONE; ANDROSTERONE; ESTROGEN; GESTAGEN; GLUCOCORTICOID; GLUCURONIDE; HYDROXYSTEROID DEHYDROGENASE; MINERALOCORTICOID; PRASTERONE; PRASTERONE SULFATE; PREGNENOLONE; PROGESTERONE; TESTOSTERONE; UNCLASSIFIED DRUG;

ACCURACY; ANDROGEN BLOOD LEVEL; ANDROGEN METABOLISM; ANDROGEN SYNTHESIS; BONE DENSITY; BREAST CANCER; CHROMATOGRAPHY; DERIVATIZATION; ENZYME ACTIVITY; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE DETERMINATION; HORMONE STRUCTURE; HORMONE SYNTHESIS; HUMAN; IMMUNOASSAY; LIQUID CHROMATOGRAPHY; MAMMARY GLAND; MASS FRAGMENTOGRAPHY; PRIORITY JOURNAL; PROSTATE CANCER; QUANTITATIVE ANALYSIS; RADIOIMMUNOASSAY; REVIEW; SENSITIVITY AND SPECIFICITY; STEROID METABOLISM; TANDEM MASS SPECTROMETRY;

3Α-DIOL; 3Α-DIOL-17G; 3Α-DIOL-3G; 3Α-DIOL-G; 4-ANDROSTENEDIONE; 4-DIONE; 5Α-ANDROSTANE-3Β, 17Β-DIOL; A-DIOL; AANEDIOL; ADT; ADTG; AENEDIOL; ANDROGEN GLUCURONIDES; ANDROST-5-ENE-3Β, 17Β-DIOL; ANDROSTANE-3Α, 17Β-DIOL; ANDROSTANE-3Α, 17Β-DIOL-17-GLUCURONIDE; ANDROSTANE-3Α, 17Β-DIOL-3-GLUCURONIDE; ANDROSTANE-3Α, 17Β-DIOL-GLUCURONIDE; ANDROSTENE-3Β, 17Β-DIOL; ANDROSTERONE; ANDROSTERONE GLUCURONIDE; APCI; APPI; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION; ATMOSPHERIC PRESSURE PHOTO IONIZATION; DEHYDROEPIANDROSTERONE; DEHYDROEPINDROSTERONE SULFATE; DHEA; DHEAS; DHT; DIHYDROTESTOSTERONE; ELECTROSPRAY IONIZATION INTERFACE; ER; ER-Α; ESI; ESTROGEN RECEPTOR-Α; ESTROGENIC RECEPTOR; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GC-MS; HORMONE-DEPENDENT MALIGNANCIES; HSD; HYBRID LINEAR ION TRAP-TRIPLE QUADRUPOLE MASS SPECTROMETER; HYDROXYSTEROID DEHYDROGENASE; INTERNAL STANDARD; IS; LC-MS; LC-MS/MS; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID-LIQUID EXTRACTION; LLE; LLOQ; LOWER LIMIT OF QUANTIFICATION; MASS SPECTROMETRY; MRM; MULTIPLE REACTION MONITORING; QTRAP; QUANTITATIVE ANALYSIS; RADIOIMMUNOASSAY; REVIEW; RIA; SEX HORMONE-BINDING GLOBULIN; SHBG; SOLID PHASE EXTRACTION; SPE; T; TESTOSTERONE; UDPGA; UHPLC-QTOF-MS; ULTRA-HIGH PRESSURE LIQUID CHROMATOGRAPHY QUADRUPOLE TIME-OF-FLIGHT MASS SPECTROMETER; URIDINE-5′-DIPHOSPHOGLUCURONIC ACID;

ANDROGENS; CHROMATOGRAPHY, LIQUID; GLUCURONIDES; HUMANS; NEOPLASMS, HORMONE-DEPENDENT; TANDEM MASS SPECTROMETRY; TUMOR MARKERS, BIOLOGICAL;

EID: 84885906763     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.09.022     Document Type: Review

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