Clinical measurement of steroid metabolism

Best Practice and Research: Clinical Endocrinology and Metabolism

Volumn 15, Issue 1, 2001, Pages 1-16

  Andrew, Ruth ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Analysis; Arterio venous sampling; Binding assay; Chromatography; Gas chromatography; High performance liquid chromatography; Mass spectrometry; Microdialysis; Radioimmunoassay; Stable isotope tracer; Steroid; Ultra violet detection

Indexed keywords

TRACER;

BINDING KINETICS; BIOSYNTHESIS; DIAGNOSTIC ERROR; DNA MICROARRAY; ENDOCRINE DISEASE; GAS CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HORMONE BINDING; HORMONE DETERMINATION; HUMAN; MASS SPECTROMETRY; MICRODIALYSIS; QUALITATIVE DIAGNOSIS; QUANTITATIVE ASSAY; RADIOIMMUNOASSAY; REVIEW; STEROID ANALYSIS; STEROID BLOOD LEVEL; STEROID METABOLISM; STEROID URINE LEVEL; ULTRAVIOLET SPECTROSCOPY;

EID: 0034964574     PISSN: 1521690X     EISSN: None     Source Type: Journal    
DOI: 10.1053/beem.2001.0116     Document Type: Article

References (59)

1. Production and metabolism of dihydrotestosterone in peripheral tissues
2. 11β-Hydroxysteroid dehydrogenase is an exclusive 11β-reductase in primary cultures of rat hepatocytes: Effect of physicochemical and hormonal manipulations
3. Aromatase Cytochrome P450, the enzyme responsible for estrogen biosynthesis
4. Cortisol metabolism in healthy young adults: Sexual dimorphism in activities of A-ring reductase but not 11B-hydroxysteroid dehydrogenases
5. Steroid 5α-reductase: Two genes/two enzymes
6. Anxiolytic effects of steroid hormones during the estrous cycle. Interactions with ethanol
7. Steroid specificity of the putative DHB receptor: Evidence that the receptor is not 11βHSD
8. Molecular endocrinology of hydroxysteroid dehydrogenases
9. Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme
10. Cloning and production of antisera to human placental 11β-hydroxysteroid dehydrogenase type 2
11. Localisation of 11β-hydroxysteroid dehydrogenase-tissue specific protector of the mineralocorticoid receptor
12. 11β-Hydroxysteroid dehydrogenase in cultured hippocampal cells reactivates inert 11-dehydrocorticosterone, potentiating neurotoxicity
13. Dehydroepiandrosterone, dehydroepiandrosterone sulfate, obesity, waist-hip ratio, and noninsulin-dependent diabetes in postmenopausal women: The Rancho Bernardo study
14. Determination of dehydroepiandrosterone sulfate in human plasma by gas chromatography/mass spectrometry using a deuterated internal standard: A method suitable for routine clinical use
15. Additional value of measurement of urinary cortisone and unconjugated cortisol metabolites in assessing the activity of 11β-hydroxysteroid dehydrogenase in vivo
16. The impact of dexamethasone pharmacokinetics on the DST: A review
17. Identification of a new inborn error in bile acid synthesis: Mutation of the oxysterol 7α-hydroxylase gene causes severe neonatal liver disease
18. Cyp7b, a novel brain cytochrome P450, catalyzes the synthesis of neurosteroids 7α-hydroxy dehydroepiandrosterone and 7α-hydroxypregnenolone
19. Orphan nuclear receptor ligands and biology
20. Analytical support for the detection and treatment of congenital adrenal hyperplasia
21. The adrenocortical hypertensive mechanism in the syndrome of apparent mineralocorticoid excess
22. A radioimmunoassay for 18-hydroxycortisol in plasma and urine
23. New perspectives in radioimmunoassay
24. Ligand assays: From electrophoresis to miniaturized microarrays
25. Quantitation of 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D by radioimmunoassay using radioiodinated tracers
26. Aldosterone and renin measurements
27. Principles of free hormone measurement
28. Differences between concentrations of salivary cortisol and cortisone and of free cortisol and cortisone in plasma during pregnancy and postpartum
29. Chemilumniscence immunoassays: An overview
30. Multi-analyte immunoassay
31. Separation of drugs by packed-column supercritical fluid chromatography
32. Steroid profile for urine: Reference values
33. Use of Sep-pak cartridges for urinary steroid extraction: Evaluation of the method for the use prior to gas chromatographic analysis
34. Steroid profiling
35. Simultaneous determination of urinary androgen glucuronides by high temperature gas chromatography-mass spectrometry
36. Gas chromatography-mass spectrometry in the investigation of on-column dehydration of steroid hormones during gas-liquid chromatography
37. External quality assessment of assays for cortisol in plasma: Use of target data obtained by gas chromatography/mass spectrometry
38. The analysis and identification of steroids
39. Detection of androgenic anabolic steroids in urine
40. High-performance liquid chromatographic analysis of corticosteroids
41. High-performance liquid chromatography of some estrogen on chemically bonded phases
42. Optimization of the high-performance liquid chromatographic separation of a mixture of natural and synthetic corticosteroids
43. The influence of temperature on the multiple separation of estrogenic steroids using mobile phases modified with β-cyclodextrin in high-performance liquid chromatography
44. Fluorometric liquid-chromatographic determination of serum cortisol
45. Chemiluminescence high performance liquid chromatography of corticosteroids using lucigenin as post-column reagent
46. Characteristics of mass fragmentation of steroid by atmospheric pressure chemical ionisation-mass spectrometry
47. Glucuronic acid conjugates
48. Direct measurement of steroid sulfate and glucuronide conjugates with high-performance liquid chromatography-mass spectrometry
49. Analysis of corticosteroids in urine by HPLC and thermospray LC/MS
50. Understanding the role of glucocorticoids in obesity: Tissue-specific alterations of corticosterone metabolism in obese Zucker rats
51. A novel coculture model for benign prostatic hyperplasia expressing both isoforms of 5α-reductase
52. Steroid hormone interconversions in human adipose tissue in vivo
53. An in vivo study of the cortisol-cortisone shuttle in subcutaneous abdominal adipose tissue
54. 11Beta-hydroxysteroid dehydrogenase deficiency in essential hypertension
55. The biological conversion of cholesterol to pregnanediol
56. Stable isotope studies on steroid metabolism and kinetics: Sulfates of 3α-hydroxy-5α-pregnane derivatives in human pregnancy
57. Daily cortisol production rate in man determined by stable isotope dilution/mass spectrometry
58. Distinguishing activities of type 1 and type 2 11β-hydroxysteroid dehydrogenases (11B-HSDs) in man using deuterated cortisol
59. Synthesis of a deuterium-labeled cortisol for the study of its rate of 11β-hydroxy dehydrogenation in man