Molecular Dynamic Simulation Reveals Damaging Impact of RAC1 F28L Mutation in the Switch I Region

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Kumar, Ambuj ^a   Rajendran, Vidya ^a   Sethumadhavan, Rao ^a   Purohit, Rituraj ^a,b  

^a VIT UNIVERSITY   (India)

^b Human Genetics Foundation   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE; MUTANT PROTEIN; RAC1 PROTEIN;

ARTICLE; CARCINOGENICITY; CHEMICAL BOND; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; NEOPLASM; PHENOTYPE; POINT MUTATION; PROTEIN STRUCTURE; SWITCH I REGION;

AMINO ACID SUBSTITUTION; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; RAC1 GTP-BINDING PROTEIN; SOLVENTS;

EID: 84885823176     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0077453     Document Type: Article

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