An siRNA designing tool with a unique functional off-target filtering approach

Journal of Biomolecular Structure and Dynamics

Volumn 31, Issue 11, 2013, Pages 1343-1357

  Das, Shaoli ^a   Ghosal, Suman ^a   Kozak, Karol ^b   Chakrabarti, Jayprokas ^a,c  

^a DEPARTMENT OF MATERIALS SCIENCE   (India)

^b ETH ZURICH   (Switzerland)

^c Gyanxet   (India)

Author keywords

functional off target filtering; multi parametric classifier; parameter weight optimization; siRNA potency; specificity; user feedback

Indexed keywords

SMALL INTERFERING RNA;

ALGORITHM; ARTICLE; DATA MINING; FALSE POSITIVE RESULT; GENE FUNCTION; GENE TARGETING; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; RNA INTERFERENCE; SUPPORT VECTOR MACHINE;

3' UNTRANSLATED REGIONS; ALGORITHMS; ALTERNATIVE SPLICING; DATA MINING; GENE ONTOLOGY; HELA CELLS; HUMANS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING;

EID: 84885638301     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2012.736758     Document Type: Article

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