메뉴 건너뛰기




Volumn 72, Issue 2, 2012, Pages 165-172

Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway

Author keywords

alternol; AMP activated protein kinase; autophagy; Bcl 2; prostate cancer

Indexed keywords

ADENYLATE KINASE; ALTERNOL; ANTINEOPLASTIC AGENT; LC3I PROTEIN; LC3II PROTEIN; PROPIDIUM IODIDE; PROTEIN; PROTEIN BCL 2; PROTEIN P27; UNCLASSIFIED DRUG;

EID: 84455162752     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.21417     Document Type: Article
Times cited : (25)

References (33)
  • 1
    • 34248335065 scopus 로고    scopus 로고
    • Prostate Cancer
    • DOI 10.1016/j.juro.2007.01.121, PII S0022534707002595
    • Penson DF, Chan JM,. Prostate cancer. J Urol 2007; 177 (6): 2020-2029. (Pubitemid 46735946)
    • (2007) Journal of Urology , vol.177 , Issue.6 , pp. 2020-2029
    • Penson, D.F.1    Chan, J.M.2
  • 3
    • 67149130467 scopus 로고    scopus 로고
    • Androgen deprivation in prostate cancer-step by step
    • Albertsen P,. Androgen deprivation in prostate cancer-step by step. N Engl J Med 2009; 360 (24): 2572-2574.
    • (2009) N Engl J Med , vol.360 , Issue.24 , pp. 2572-2574
    • Albertsen, P.1
  • 5
    • 77649267690 scopus 로고    scopus 로고
    • Role of targeted therapy in the treatment of advanced prostate cancer
    • Fizazi K, Sternberg CN, Fitzpatrick JM, Watson RW, Tabesh M,. Role of targeted therapy in the treatment of advanced prostate cancer. BJU Int 2010; 105 (6): 748-767.
    • (2010) BJU Int , vol.105 , Issue.6 , pp. 748-767
    • Fizazi, K.1    Sternberg, C.N.2    Fitzpatrick, J.M.3    Watson, R.W.4    Tabesh, M.5
  • 6
    • 77949875831 scopus 로고    scopus 로고
    • Novel targeted therapeutics for metastatic castration-resistant prostate cancer
    • Antonarakis ES, Carducci MA, Eisenberger MA,. Novel targeted therapeutics for metastatic castration-resistant prostate cancer. Cancer Lett 2010; 291 (1): 1-13.
    • (2010) Cancer Lett , vol.291 , Issue.1 , pp. 1-13
    • Antonarakis, E.S.1    Carducci, M.A.2    Eisenberger, M.A.3
  • 7
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman BJ, Feldman D,. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001; 1 (1): 34-45. (Pubitemid 33741879)
    • (2001) Nature Reviews Cancer , vol.1 , Issue.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 8
    • 35548953565 scopus 로고    scopus 로고
    • Alternol inhibits proliferation and induces apoptosis in mouse lymphocyte leukemia (L1210) cells
    • DOI 10.1007/s11010-007-9560-0
    • Liu ZZ, Zhu J, Sun B, Liu S, Geng S, Liu X, Li CL,. Alternol inhibits proliferation and induces apoptosis in mouse lymphocyte leukemia (L1210) cells. Mol Cell Biochem 2007; 306 (1-2): 115-122. (Pubitemid 350001823)
    • (2007) Molecular and Cellular Biochemistry , vol.306 , Issue.1-2 , pp. 115-122
    • Liu, Z.-Z.1    Zhu, J.2    Sun, B.3    Liu, S.4    Geng, S.5    Liu, X.6    Li, C.-L.7
  • 9
    • 0015211527 scopus 로고
    • Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia
    • Wani MC, Taylor HL, Wall ME, Coggon P, McPhail AT,. Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J Am Chem Soc 1971; 93 (9): 2325-2327.
    • (1971) J Am Chem Soc , vol.93 , Issue.9 , pp. 2325-2327
    • Wani, M.C.1    Taylor, H.L.2    Wall, M.E.3    Coggon, P.4    McPhail, A.T.5
  • 10
    • 38949162107 scopus 로고    scopus 로고
    • Cell growth inhibition, G2M cell cycle arrest, and apoptosis induced by the novel compound Alternol in human gastric carcinoma cell line MGC803
    • Liu X, Wang J, Sun B, Zhang Y, Zhu J, Li C,. Cell growth inhibition, G2M cell cycle arrest, and apoptosis induced by the novel compound Alternol in human gastric carcinoma cell line MGC803. Invest New Drugs 2007; 25 (6): 505-517.
    • (2007) Invest New Drugs , vol.25 , Issue.6 , pp. 505-517
    • Liu, X.1    Wang, J.2    Sun, B.3    Zhang, Y.4    Zhu, J.5    Li, C.6
  • 11
    • 33646417329 scopus 로고    scopus 로고
    • DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: Implications for the androgen receptor functions and regulation
    • DOI 10.1016/j.febslet.2006.03.041, PII S0014579306003565
    • Alimirah F, Chen J, Basrawala Z, Xin H, Choubey D,. DU-145 and PC-3 human prostate cancer cell lines express androgen receptor: Implications for the androgen receptor functions and regulation. FEBS Lett 2006; 580 (9): 2294-2300. (Pubitemid 43675636)
    • (2006) FEBS Letters , vol.580 , Issue.9 , pp. 2294-2300
    • Alimirah, F.1    Chen, J.2    Basrawala, Z.3    Xin, H.4    Choubey, D.5
  • 13
    • 0034234571 scopus 로고    scopus 로고
    • LNCaP progression model of human prostate cancer: Androgen-independence and osseous metastasis
    • DOI 10.1002/1097-0045(20000701)44:2<91::AID-PROS1>3.0.CO;2-L
    • Thalmann GN, Sikes RA, Wu TT, Degeorges A, Chang SM, Ozen M, Pathak S, Chung LW,. LNCaP progression model of human prostate cancer: Androgen-independence and osseous metastasis. Prostate 2000; 44 (2): 91-103 Jul 101;144(102). (Pubitemid 30419183)
    • (2000) Prostate , vol.44 , Issue.2 , pp. 91-103
    • Thalmann, G.N.1    Sikes, R.A.2    Wu, T.T.3    Degeorges, A.4    Chang, S.-M.5    Ozen, M.6    Pathak, S.7    Chung, L.W.K.8
  • 14
    • 33644834121 scopus 로고    scopus 로고
    • Mitochondrial DNA determines androgen dependence in prostate cancer cell lines
    • DOI 10.1038/sj.onc.1209190, PII 1209190
    • Higuchi M, Kudo T, Suzuki S, Evans TT, Sasaki R, Wada Y, Shirakawa T, Sawyer JR, Gotoh A,. Mitochondrial DNA determines androgen dependence in prostate cancer cell lines. Oncogene 2006; 25 (10): 1437-1445. (Pubitemid 43361929)
    • (2006) Oncogene , vol.25 , Issue.10 , pp. 1437-1445
    • Higuchi, M.1    Kudo, T.2    Suzuki, S.3    Evans, T.T.4    Sasaki, R.5    Wada, Y.6    Shirakawa, T.7    Sawyer, J.R.8    Gotoh, A.9
  • 15
    • 48649083369 scopus 로고    scopus 로고
    • Phosphoinositide 3-OH kinase p85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers
    • Zhu Q, Youn H, Tang J, Tawfik O, Dennis K, Terranova PF, Du J, Raynal P, Thrasher JB, Li B,. Phosphoinositide 3-OH kinase p85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers. Oncogene 2008; 27 (33): 4569-4579.
    • (2008) Oncogene , vol.27 , Issue.33 , pp. 4569-4579
    • Zhu, Q.1    Youn, H.2    Tang, J.3    Tawfik, O.4    Dennis, K.5    Terranova, P.F.6    Du, J.7    Raynal, P.8    Thrasher, J.B.9    Li, B.10
  • 16
    • 21744456403 scopus 로고    scopus 로고
    • Proanthocyanidin from grape seeds enhances doxorubicin-induced antitumor effect and reverses drug resistance in doxorubicin-resistant K562/DOX cells
    • Zhang XY, Li WG, Wu YJ, Bai DC, Liu NF,. Proanthocyanidin from grape seeds enhances doxorubicin-induced antitumor effect and reverses drug resistance in doxorubicin-resistant K562/DOX cells. Can J Physiol Pharmacol 2005; 83 (3): 309-318.
    • (2005) Can J Physiol Pharmacol , vol.83 , Issue.3 , pp. 309-318
    • Zhang, X.Y.1    Li, W.G.2    Wu, Y.J.3    Bai, D.C.4    Liu, N.F.5
  • 17
    • 77955100283 scopus 로고    scopus 로고
    • Isoliquiritigenin, a natural anti-oxidant, selectively inhibits the proliferation of prostate cancer cells
    • Zhang X, Yeung ED, Wang J, Panzhinskiy EE, Tong C, Li W, Li J,. Isoliquiritigenin, a natural anti-oxidant, selectively inhibits the proliferation of prostate cancer cells. Clin Exp Pharmacol Physiol 2010; 37 (8): 841-847.
    • (2010) Clin Exp Pharmacol Physiol , vol.37 , Issue.8 , pp. 841-847
    • Zhang, X.1    Yeung, E.D.2    Wang, J.3    Panzhinskiy, E.E.4    Tong, C.5    Li, W.6    Li, J.7
  • 18
    • 60649110428 scopus 로고    scopus 로고
    • A newly synthetic chromium complex-Chromium (d-phenylalanine)(3) activates AMP-activated protein kinase and stimulates glucose transport
    • Zhao P, Wang J, Ma H, Xiao Y, He L, Tong C, Wang Z, Zheng Q, Dolence EK, Nair S, Ren J, Li J,. A newly synthetic chromium complex-Chromium (d-phenylalanine)(3) activates AMP-activated protein kinase and stimulates glucose transport. Biochem Pharmacol 2009; 77 (6): 1002-1010.
    • (2009) Biochem Pharmacol , vol.77 , Issue.6 , pp. 1002-1010
    • Zhao, P.1    Wang, J.2    Ma, H.3    Xiao, Y.4    He, L.5    Tong, C.6    Wang, Z.7    Zheng, Q.8    Dolence, E.K.9    Nair, S.10    Ren, J.11    Li, J.12
  • 24
    • 70449107252 scopus 로고    scopus 로고
    • Redox-directed cancer therapeutics: Molecular mechanisms and opportunities
    • Wondrak GT,. Redox-directed cancer therapeutics: Molecular mechanisms and opportunities. Antioxid Redox Sign 2009; 11 (12): 3013-3069.
    • (2009) Antioxid Redox Sign , vol.11 , Issue.12 , pp. 3013-3069
    • Wondrak, G.T.1
  • 26
    • 0019805521 scopus 로고
    • Taxol-induced polymerization of purified tubulin. Mechanism of action
    • Kumar N,. Taxol-induced polymerization of purified tubulin. Mechanism of action. J Biol Chem 1981; 256 (20): 10435-10441. (Pubitemid 12219438)
    • (1981) Journal of Biological Chemistry , vol.256 , Issue.20 , pp. 10435-10441
    • Kumar, N.1
  • 27
    • 0026516994 scopus 로고
    • Mechanism of action of taxol
    • Horwitz SB,. Mechanism of action of taxol. Trends Pharmacol Sci 1992; 13 (4): 134-136.
    • (1992) Trends Pharmacol Sci , vol.13 , Issue.4 , pp. 134-136
    • Horwitz, S.B.1
  • 28
    • 0029056675 scopus 로고
    • Inactivation of Bcl-2 by phosphorylation
    • Haldar S, Jena N, Croce CM,. Inactivation of Bcl-2 by phosphorylation. Proc Natl Acad Sci USA 1995; 92 (10): 4507-4511.
    • (1995) Proc Natl Acad Sci USA , vol.92 , Issue.10 , pp. 4507-4511
    • Haldar, S.1    Jena, N.2    Croce, C.M.3
  • 29
    • 38349167518 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: Updated survival in the TAX 327 study
    • Berthold DR, Pond GR, Soban F, de Wit R, Eisenberger M, Tannock IF,. Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer: Updated survival in the TAX 327 study. J Clin Oncol 2008; 26 (2): 242-245.
    • (2008) J Clin Oncol , vol.26 , Issue.2 , pp. 242-245
    • Berthold, D.R.1    Pond, G.R.2    Soban, F.3    De Wit, R.4    Eisenberger, M.5    Tannock, I.F.6
  • 32
    • 33745213627 scopus 로고    scopus 로고
    • AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer
    • DOI 10.1113/jphysiol.2006.108324
    • Motoshima H, Goldstein BJ, Igata M, Araki E,. AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer. J Physiol 2006; 574 (Pt 1): 63-71. (Pubitemid 43905797)
    • (2006) Journal of Physiology , vol.574 , Issue.1 , pp. 63-71
    • Motoshima, H.1    Goldstein, B.J.2    Igata, M.3    Araki, E.4
  • 33
    • 43949131433 scopus 로고    scopus 로고
    • Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis
    • White E,. Autophagic cell death unraveled: Pharmacological inhibition of apoptosis and autophagy enables necrosis. Autophagy 2008; 4 (4): 399-401. (Pubitemid 351705133)
    • (2008) Autophagy , vol.4 , Issue.4 , pp. 399-401
    • White, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.