Case-control association analysis of Dopamine receptor polymorphisms in alcohol dependence: A pilot study in Indian males

BMC Research Notes

Volumn 6, Issue 1, 2013, Pages

  Prasad, Pushplata ^a,b   Ambekar, Atul ^a   Vaswani, Meera ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b THE ENERGY AND RESOURCES INSTITUTE   (India)

Author keywords

Alcohol dependence; Case control study; Dopamine receptors; Genetic association; Polymorphisms

Indexed keywords

ANIMALIA;

DOPAMINE 1 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DRD1 PROTEIN, HUMAN; DRD3 PROTEIN, HUMAN; DRD4 PROTEIN, HUMAN;

ADULT; ALCOHOLISM; ALLELE; ARTICLE; CASE CONTROL STUDY; GENE DUPLICATION; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; HUMAN; INDIA; MALE; MIDDLE AGED; PILOT STUDY; POLYMERASE CHAIN REACTION; RISK;

ADULT; ALCOHOLISM; ALLELES; CASE-CONTROL STUDIES; GENE DUPLICATION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INDIA; MALE; MIDDLE AGED; ODDS RATIO; PILOT PROJECTS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D3; RECEPTORS, DOPAMINE D4;

EID: 84885537122     PISSN: None     EISSN: 17560500     Source Type: Journal    
DOI: 10.1186/1756-0500-6-418     Document Type: Article

References (49)

1. Evidence for addiction-like behavior in the rat. Deroche-Gamonet V, Belin D, Piazza PV, Science 2004 305 5686 1014 1017 10.1126/science.1099020 15310906
2. The mesolimbic dopamine system: the final common pathway for the reinforcing effect of drugs of abuse? Pierce RC, Kumaresan V, Neurosci Biobehav Rev 2006 30 2 215 238 10.1016/j.neubiorev.2005.04.016 16099045
3. Oral alcohol selfadministration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants. Weiss F, Lorang MT, Bloom FE, Koob GF, J Pharmacol Exp Ther 1993 267 250 258 8229752
4. Ethanol self-infusion into the ventral tegmental area by alcohol preferring rats. Gatto GJ, McBride WJ, Murphy JM, Lumeng L, Li TK, Alcohol 1994 11 557 564 10.1016/0741-8329(94)90083-3 7865158
5. Dopamine release during ethanol drinking in AA rats. Nurmi M, Sinclair JD, Kiianmaa K, Alcohol Clin Exp Res 1998 22 8 1628 1633 10.1111/j.1530-0277. 1998.tb03959.x 9835274
6. Suppression of ethanol-reinforced behavior by naltrexone is associated with attenuation of the ethanol-induced increase in dialysate dopamine levels in the nucleus accumbens. Gonzales RA, Weiss F, J Neurosci 1998 18 24 10663 10671 9852601
7. Intracranial self-administration of ethanol within the ventral tegmental area of male Wistar rats: evidence for involvement of dopamine neurons. Rodd ZA, Melendez RI, Bell RL, Kuc KA, Zhang Y, Murphy JM, McBride WJ, J Neurosci 2004 24 5 1050 1057 10.1523/JNEUROSCI.1319-03.2004 14762123
8. Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum. Martinez D, Gil R, Slifstein M, Hwang DR, Huang Y, Perez A, Kegeles L, Talbot P, Evans S, Krystal J, Laruelle M, Abi-Dargham A, Biol Psychiatry 2005 58 10 779 786 10.1016/j.biopsych.2005.04.044 16018986
9. A haplotype of the DRD1 gene is associated with alcohol dependence. Batel P, Houchi H, Daoust M, Ramoz N, Naassila M, Gorwood P, Alcohol Clin Exp Res 2008 32 4 567 572 10.1111/j.1530-0277.2008.00618.x 18341651
10. The genetics of alcoholism: identifying specific genes through family studies. Edenberg HJ, Foround T, Addict Biol 2006 11 386 396 10.1111/j.1369-1600.2006.00035.x 16961766
11. An overview of the genetic susceptibility to alcoholism. Buscemi L, Turchi C, Med Sci Law 2011 51 Suppl 1 2 S6 22021628
12. The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. Morozova TV, Goldman D, Mackay TF, Anholt RR, Genome Biol 2012 13 2 239 10.1186/gb-2012-13-2-239 22348705
13. The behavioral genetics of alcoholism. McGue M, Current Directions in Psychological Science 1999 8 109 115 10.1111/1467-8721.00026
14. D2 dopamine receptor gene (DRD2) allele and haplotype frequencies in alcohol dependent and control subjects: no association with phenotype or severity of phenotype. Gelernter J, Kranzler H, Neuropsychopharmacology 1999 20 6 640 649 10.1016/S0893-133X(98)00110-9 10327432
15. The A1 allele of the DRD2 gene (TaqI A polymorphisms) is associated with antisocial personality in a sample of alcohol-dependent patients. Ponce G, Jimenez-Arriero MA, Rubio G, Hoenicka J, Ampuero I, Ramos JA, Palomo T, Eur Psychiatry 2003 18 7 356 360 10.1016/j.eurpsy.2003.06.006 14643564
16. Dopamine D2 receptor polymorphisms and susceptibility to alcohol dependence in Indian males: a preliminary study. Prasad P, Ambekar A, Vaswani M, BMC Med Genet 2010 11 24 20146828
17. D1 and D2 receptor antagonist injections in the prefrontal cortex selectively impair spatial learning in mice. Rinaldi A, Mandillo S, Oliverio A, Mele A, Neuropsychopharmacology 2007 32 2 309 319 10.1038/sj.npp.1301176 16900106
18. Li J, Li J, Liu X, Qin S, Guan Y, Liu Y, Cheng Y, Chen X, Li W, Wang S, Xiong M, Kuzhikandathil EV, Ye JH, Zhang C, MicroRNA expression profile and functional analysis reveal that miR-382 is a critical novel gene of alcohol addiction Mol Med: EMBO 2013
19. Studies of the potential role of the dopamine D1 receptor gene in addictive behaviors. Comings DE, Gade R, Wu S, Chiu C, Dietz G, Muhleman D, Saucier G, Ferry L, Rosenthal RJ, Lesieur HR, Rugle LJ, MacMurray P, Mol Psychiatry 1997 2 1 44 56 10.1038/sj.mp.4000207 9154217
20. Distribution of dopamine D3 receptor expressing neurons in the human forebrain: comparison with D2 receptor expressing neurons. Gurevich EV, Joyce JN, Neuropsychopharmacology 1999 20 1 60 80 10.1016/S0893-133X(98)00066-9 9885786
21. Genetics of dopamine receptors and drug addiction: a comprehensive review. Le Foll B, Gallo A, Le Strat Y, Lu L, Gorwood P, Behav Pharmacol 2009 20 1 1 17 10.1097/FBP.0b013e3283242f05 19179847
22. Imaging dopamine's role in drug abuse and addiction. Volkow ND, Fowler JS, Wang GJ, Baler R, Telang F, Neuropharmacology 2009 56 1 3 8 18617195
23. Lack of association between alcohol-dependence and D3 dopamine receptor gene in three independent samples. Gorwood P, Martres MP, Adès J, Sokoloff P, Noble EP, Geijer T, Blum K, Neiman J, Jönsson E, Feingold J, et al. Am J Med Genet 1995 60 6 529 531 10.1002/ajmg.1320600608 8825889
24. No association between polymorphisms in the human dopamine D3 and D4 receptors genes and alcoholism. Parsian A, Chakraverty S, Fisher L, Cloninger CR, Am J Med Genet 1997 74 3 281 285 10.1002/(SICI)1096-8628(19970531)74: 3<281::AID-AJMG8>3.0.CO;2-T 9184311
25. Genetic influences on craving for alcohol. Agrawal A, Wetherill L, Bucholz KK, Kramer J, Kuperman S, Lynskey MT, Nurnberger JI Jr, Schuckit M, Tischfield JA, Edenberg HJ, Foroud T, Bierut LJ, Addict Behav 2013 38 2 1501 1508 10.1016/j.addbeh.2012.03.021 22481050
26. Homozygosity at the dopamine D3 receptor gene is associated with opiate dependence. Duaux E, Gorwood P, Griffon N, Bourdel MC, Sautel F, Sokoloff P, Schwartz JC, Ades J, Lôo H, Poirier MF, Mol Psychiatry 1998 3 4 333 336 10.1038/sj.mp.4000409 9702742
27. Association between dopamine receptor D3 gene BalI polymorphism and cognitive impulsiveness in alcohol-dependent men. Limosin F, Romo L, Batel P, Adès J, Boni C, Gorwood P, Eur Psychiatry 2005 20 3 304 306 10.1016/j.eurpsy.2005.02.004 15935433
28. The DRD4 exon 3 VNTR polymorphism and addiction-related phenotypes:a review. McGeary J, Pharmacol Biochem Behav 2009 93 3 222 229 10.1016/j.pbb.2009.03.010 19336242
29. Ray R, The Extent Pattern and Trends of drug abuse in India: National Survey Ministry of Social Justice and Empowerment, Government of India and United Nations Office on Drugs and Crime India: New Delhi 2004
30. American Psychiatric Association, Diagnostic and statistical manual of mental disorders. 4 Washington, DC: American Psychiatric Press 1994
31. Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO Collaborative Project on Early Detection of Persons with Harmful Alcohol Consumption-II. Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M, Addiction 1993 88 791 804 10.1111/j.1360-0443.1993.tb02093.x 8329970
32. A simple salting out procedure for extracting DNA from human nucleated cells. Miller SA, Dykes DD, Polesky HF, Nucleic Acids Res 1988 16 1215 10.1093/nar/16.3.1215 3344216
33. Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes. Prasad P, Kumar KM, Ammini AC, Gupta A, Gupta R, Thelma BK, BMC Genet 2008 9 26 18366720
34. Power and sample size calculations for case-control genetic association tests when errors present: application to single nucleotide polymorphisms. Gordon D, Finch SJ, Nothnagel M, Ott J, Hum Hered 2002 54 22 33 10.1159/000066696 12446984
35. Errors and linkage disequilibrium interact multiplicatively when computing sample sizes for genetic case-control association studies. Gordon D, Levenstien MA, Finch SJ, Ott J, Pac Symp Biocomput 2003 490 501
36. No association between the dopamine D3 receptor gene and Korean alcohol dependence. Lee MS, Ryu SH, Psychiatr Genet 2002 12 3 173 176 10.1097/00041444-200209000-00010 12218663
37. A48G polymorphism in the D1 receptor genes associated with bipolar I disorder. Severino G, Congiu D, Serreli C, De Lisa R, Chillotti C, Del Zompo M, Piccardi MP, Am J Med Genet B Neuropsychiatr Genet 2005 134B 1 37 38 10.1002/ajmg.b.30116 15704231
38. Dopamine receptor D1 gene -48A/G polymorphism is associated with bipolar illness but not with schizophrenia in a Polish population. Dmitrzak-Weglarz M, Rybakowski JK, Slopien A, Czerski PM, Leszczynska-Rodziewicz A, Kapelski P, Kaczmarkiewicz-Fass M, Hauser J, Neuropsychobiology 2006 53 1 46 50 10.1159/000090703 16397404
39. Association between dopamine receptor D1 gene DdeI polymorphism and sensation seeking in alcohol-dependent men. Limosin F, Loze JY, Rouillon F, Adès J, Gorwood P, Alcohol Clin Exp Res 2003 27 8 1226 1228 10.1097/01.ALC.0000081624.57507.87 12966314
40. 5′ UTR polymorphism of dopamine receptor D1 (DRD1) associated with severity and temperament of alcoholism. Kim DJ, Park BL, Yoon S, Lee HK, Joe KH, Cheon YH, Gwon DH, Cho SN, Lee HW, NamGung S, Shin HD, Biochem Biophys Res Commun 2007 357 4 1135 1141 10.1016/j.bbrc.2007.04.074 17466946
41. A serine to glycine substitution at position 9 in the extracellular N-terminal part of the dopamine D3 receptor protein: no role in the genetic predisposition to bipolar affective disorder. Rietschel M, Nöthen MM, Lannfelt L, Sokoloff P, Schwartz JC, Lanczik M, Fritze J, Cichon S, Fimmers R, Körner J, Moller HJ, Propping P, Psychiatry Res 1993 46 3 253 259 10.1016/0165-1781(93)90093-V 8493294
42. Dopamine D1, D2 and D3 receptor genes in alcohol dependence. Sander T, Harms H, Podschus J, Finckh U, Nickel B, Rolfs A, Rommelspacher H, Schmidt LG, Psychiatr Genet 1995 5 4 171 176 10.1097/00041444-199524000-00004 8750359
43. No association of dopamine receptor sensitivity in vivo with genetic predisposition for alcoholism and DRD2/DRD3 gene polymorphisms in alcohol dependence. Wiesbeck GA, Dürsteler-MacFarland KM, Wurst FM, Walter M, Petitjean S, Müller S, Wodarz N, Böning J, Addict Biol 2006 11 1 72 75 10.1111/j.1369-1600.2006.00003.x 16759339
44. Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD). McCracken JT, Smalley SL, McGough JJ, Crawford L, Del'Homme M, Cantor RM, Liu A, Nelson SF, Mol Psychiatry 2000 5 531 536 10.1038/sj.mp.4000770 11032387
45. The polymorphic nature of the human dopamine D4 receptor gene: a comparative analysis of known variants and a novel 27 bp deletion in the promoter region. Szantai E, Szmola R, Sasvari-Szekely M, Guttman A, Ronai Z, BMC Genet 2005 6 39 15985158
46. Association between the 120-bp duplication of the dopamine D4 receptor gene and attention deficit hyperactivity disorder: genetic and molecular analyses. Kereszturi E, Kiraly O, Csapo Z, Tarnok Z, Gadoros J, Sasvari-Szekely M, Nemoda Z, Am J Med Genet B Neuropsychiatr Genet 2007 144B 2 231 236 10.1002/ajmg.b.30444 17171658
47. Association of dopamine D4 receptor (DRD4) polymorphisms with attention deficit hyperactivity disorder in Indian population. Bhaduri N, Das M, Sinha S, Chattopadhyay A, Gangopadhyay PK, Chaudhuri K, Singh M, Mukhopadhyay K, Am J Med Genet B Neuropsychiatr Genet 2006 141B 1 61 66 10.1002/ajmg.b.30225 16331654
48. No evidence for the association of DRD4 with ADHD in a Taiwanese population within-family study. Brookes KJ, Xu X, Chen CK, Huang YS, Wu YY, Asherson P, BMC Med Genet 2005 6 31 16143039
49. Association of a duplicated repeat polymorphism in the 5′-untranslated region of the DRD4 gene with novelty seeking. Rogers G, Joyce P, Mulder R, Sellman D, Miller A, Allington M, Olds R, Wells E, Kennedy M, Am J Med Genet B Neuropsychiatr Genet 2004 126B 1 95 98 10.1002/ajmg.b.20133 15048656