5′ UTR polymorphism of dopamine receptor D1 (DRD1) associated with severity and temperament of alcoholism

Biochemical and Biophysical Research Communications

Volumn 357, Issue 4, 2007, Pages 1135-1141

  Kim, Dai Jin ^a   Park, Byung Lae ^b   Yoon, Sujung ^c   Lee, Hae Kook ^d   Joe, Keun Ho ^e   Cheon, Young Hoon ^f   Gwon, Do Hoon ^g   Cho, Sung Nam ^g   Lee, Hye Won ^b   NamGung, Suk ^b   Shin, Hyoung Doo ^b  

^a Holy Family Hospital   (South Korea)

^b SNP Genetics Inc   (South Korea)

^c St Paul's Hospital   (South Korea)

^d Uijeongbu St Mary's Hospital   (South Korea)

^e Glory Hospital   (South Korea)

^f Kilian Keaney Emotion Behavior Research Institute   (South Korea)

^g Bugok National Hospital   (South Korea)

Author keywords

AUDIT; DRD gene family; Korean population; Risk of alcoholism; Severity; Single nucleotide polymorphism (SNP); Temperament

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE 5 RECEPTOR;

5' UNTRANSLATED REGION; ADULT; AGED; ALCOHOLISM; ARTICLE; AVOIDANCE BEHAVIOR; CONTROLLED STUDY; DISEASE SEVERITY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENOTYPE; HEREDITY; HUMAN; KOREA; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; TEMPERAMENT; CLASSIFICATION; GENETIC PREDISPOSITION; GENETICS; HOSPITALIZATION; METHODOLOGY; MIDDLE AGED; PREVALENCE; PSYCHOLOGICAL ASPECT; RISK ASSESSMENT; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

5' UNTRANSLATED REGIONS; ADULT; AGED; ALCOHOLISM; DNA MUTATIONAL ANALYSIS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; KOREA; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVALENCE; RECEPTORS, DOPAMINE D1; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX;

EID: 34248157569     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.04.074     Document Type: Article

References (38)

1. Agarwal D. The genetic basis of common diseases (2002), Oxford University Press, UK pp. 876-913
2. Walters G.D. The heritability of alcohol abuse and dependence: a meta-analysis of behavior genetic research. Am. J. Drug Alcohol Abuse 28 (2002) 557-584
3. Robbins T.W., and Everitt B.J. Drug addiction: bad habits add up. Nature 398 (1999) 567-570
4. Gingrich J.A., and Caron M.G. Recent advances in the molecular biology of dopamine receptors. Annu. Rev. Neurosci. 16 (1993) 299-321
5. Thomasson H.R., Edenberg H.J., Crabb D.W., Mai X.L., Jerome R.E., Li T.K., Wang S.P., Lin Y.T., Lu R.B., and Yin S.J. Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am. J. Hum. Genet. 48 (1991) 677-681
6. Chen W.J., Loh E.W., Hsu Y.P., Chen C.C., Yu J.M., and Cheng A.T. Alcohol-metabolising genes and alcoholism among Taiwanese Han men: independent effect of ADH2, ADH3 and ALDH2. Br. J. Psychiatry 168 (1996) 762-767
7. Cruz C., Camarena B., Mejia J.M., Paez F., Eroza V., Ramon De La Fuente J., Kershenobich D., and Nicolini H. The dopamine D2 receptor gene TaqI A1 polymorphism and alcoholism in a Mexican population. Arch. Med. Res. 26 (1995) 421-426
8. Tomitaka M., Tomitaka S., Otuka Y., Kim K., Matuki H., Sakamoto K., and Tanaka A. Association between novelty seeking and dopamine receptor D4 (DRD4) exon III polymorphism in Japanese subjects. Am. J. Med. Genet. 88 (1999) 469-471
9. Han Y., Gu S., Oota H., Osier M.V., Pakstis A.J., Speed W.C., Kidd J.R., and Kidd K.K. Evidence of positive selection on a class I ADH locus. Am. J. Hum. Genet. 80 (2007) 441-456
10. Li T.K., Yin S.J., Crabb D.W., O'Connor S., and Ramchandani V.A. Genetic and environmental influences on alcohol metabolism in humans. Alcohol. Clin. Exp. Res. 25 (2001) 136-144
11. Choi I.G., Son H.G., Yang B.H., Kim S.H., Lee J.S., Chai Y.G., Son B.K., Kee B.S., Park B.L., Kim L.H., Choi Y.H., and Shin H.D. Scanning of genetic effects of alcohol metabolism gene (ADH1B and ADH1C) polymorphisms on the risk of alcoholism. Hum. Mutat. 26 (2005) 224-234
12. Babor T.F., de la Fuente J.R., Saunders J.R., and Grant M. AUDIT-the alcohol use disorders identification test: Guidelines for use in primary health care (1989), World Health Organization, Geneva
13. Skinner H.A., and Allen B.A. Alcohol dependence syndrome: measurement and validation. J. Abnorm. Psychol. 91 (1982) 199-209
14. Sung S.M., Kim J.H., Yang E., Abrams K.Y., and Lyoo I.K. Reliability and validity of the Korean version of the temperament and character inventory. Compr. Psychiatry 43 (2002) 235-243
15. Beck A.T., Steer R.A., and Carbin M.G. Psychometric properties of the Beck Depression Inventory: Twenty-five years of evaluation. Clin. Psychol. Rev. 8 (1988) 77-100
16. Livak K.J. Allelic discrimination using fluorogenic probes and the 5′ nuclease assay. Genet. Anal. 14 (1999) 143-149
17. Hedrick P.W. Gametic disequilibrium measures: proceed with caution. Genetics 117 (1987) 331-341
18. Hedrick P., and Kumar S. Mutation and linkage disequilibrium in human mtDNA. Eur. J. Hum. Genet. 9 (2001) 969-972
19. Stephens M., Smith N.J., and Donnelly P. A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68 (2001) 978-989
20. Cichon S., Nothen M.M., Rietschel M., Korner J., and Propping P. Single-strand conformation analysis (SSCA) of the dopamine D1 receptor gene (DRD1) reveals no significant mutation in patients with schizophrenia and manic depression. Biol. Psychiatry 36 (1994) 850-853
21. Ohara K., Ulpian C., Seeman P., Sunahara R.K., Van Tol H.H., and Niznik H.B. Schizophrenia: dopamine D1 receptor sequence is normal, but has DNA polymorphisms. Neuropsychopharmacology 8 (1993) 131-135
22. Sander T., Harms H., Podschus J., Finckh U., Nickel B., Rolfs A., Rommelspacher H., and Schmidt L.G. Dopamine D1, D2 and D3 receptor genes in alcohol dependence. Psychiatr. Genet. 5 (1995) 171-176
23. Liu Q., Sobell J.L., Heston L.L., and Sommer S.S. Screening the dopamine D1 receptor gene in 131 schizophrenics and eight alcoholics: identification of polymorphisms but lack of functionally significant sequence changes. Am. J. Med. Genet. 60 (1995) 165-171
24. Kojima H., Ohmori O., Shinkai T., Terao T., Suzuki T., and Abe K. Dopamine D1 receptor gene polymorphism and schizophrenia in Japan. Am. J. Med. Genet. 88 (1999) 116-119
25. Liu H.C., Chen C.K., Leu S.J., Wu H.T., and Lin S.K. Association between dopamine receptor D1 A-48G polymorphism and methamphetamine abuse. Psychiatry Clin. Neurosci. 60 (2006) 226-231
26. Dmitrzak-Weglarz M., Rybakowski J.K., Slopien A., Czerski P.M., Leszczynska-Rodziewicz A., Kapelski P., Kaczmarkiewicz-Fass M., and Hauser J. Dopamine receptor D1 gene -48A/G polymorphism is associated with bipolar illness but not with schizophrenia in a polish population. Neuropsychobiology 53 (2006) 46-50
27. Comings D.E., Gade R., Wu S., Chiu C., Dietz G., Muhleman D., Saucier G., Ferry L., Rosenthal R.J., Lesieur H.R., Rugle L.J., and MacMurray P. Studies of the potential role of the dopamine D1 receptor gene in addictive behaviors. Mol. Psychiatry 2 (1997) 44-56
28. Limosin F., Loze J.Y., Rouillon F., Ades J., and Gorwood P. Association between dopamine receptor D1 gene DdeI polymorphism and sensation seeking in alcohol-dependent men. Alcohol. Clin. Exp. Res. 27 (2003) 1226-1228
29. Cloninger C.R., Bohman M., and Sigvardsson S. Inheritance of alcohol abuse. Cross-fostering analysis of adopted men. Arch. Gen. Psychiatry 38 (1981) 861-868
30. Le Bon O., Basiaux P., Streel E., Tecco J., Hanak C., Hansenne M., Ansseau M., Pelc I., Verbanck P., and Dupont S. Personality profile and drug of choice; a multivariate analysis using Cloninger's TCI on heroin addicts, alcoholics, and a random population group. Drug. Alcohol. Depend. 73 (2004) 175-182
31. Basiaux P., le Bon O., Dramaix M., Massat I., Souery D., Mendlewicz J., Pelc I., and Verbanck P. Temperament and Character Inventory (TCI) personality profile and sub-typing in alcoholic patients: a controlled study. Alcohol Alcoholism 36 (2001) 584-587
32. Chou I.C., Tsai C.H., Lee C.C., Kuo H.T., Hsu Y.A., Li C.I., and Tsai F.J. Association analysis between Tourette's syndrome and dopamine D1 receptor gene in Taiwanese children. Psychiatr. Genet. 14 (2004) 219-221
33. Arinami T., Itokawa M., Aoki J., Shibuya H., Ookubo Y., Iwawaki A., Ota K., Shimizu H., Hamaguchi H., and Toru M. Further association study on dopamine D2 receptor variant S311C in schizophrenia and affective disorders. Am. J. Med. Genet. 67 (1996) 133-138
34. Arinami T., Gao M., Hamaguchi H., and Toru M. A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia. Hum. Mol. Genet. 6 (1997) 577-582
35. Lawford B.R., Young R.M., Swagell C.D., Barnes M., Burton S.C., Ward W.K., Heslop K.R., Shadforth S., van Daal A., and Morris C.P. The C/C genotype of the C957T polymorphism of the dopamine D2 receptor is associated with schizophrenia. Schizophr. Res. 73 (2005) 31-37
36. Soma M., Nakayama K., Rahmutula D., Uwabo J., Sato M., Kunimoto M., Aoi N., Kosuge K., and Kanmatsuse K. Ser9Gly polymorphism in the dopamine D3 receptor gene is not associated with essential hypertension in the Japanese. Med. Sci. Monit. 8 (2002) CR1-CR4
37. Szantai E., Szilagyi A., Guttman A., Sasvari-Szekely M., and Ronai Z. Genotyping and haplotyping of the dopamine D4 receptor gene by capillary electrophoresis. J. Chromatogr. A 1053 (2004) 241-245
38. Seeman P., Ulpian C., Chouinard G., Van Tol H.H., Dwosh H., Lieberman J.A., Siminovitch K., Liu I.S., Waye J., Voruganti P., et al. Dopamine D4 receptor variant, D4GLYCINE194, in Africans, but not in Caucasians: no association with schizophrenia. Am. J. Med. Genet. 54 (1994) 384-390