The genetic basis of alcoholism: Multiple phenotypes, many genes, complex networks

Genome Biology

Volumn 13, Issue 2, 2012, Pages

  Morozova, Tatiana V ^a   Goldman, David ^b   Mackay, Trudy F C ^a   Anholt, Robert R H ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

Addiction; Alcohol sensitivity; Disease susceptibility; Genome wide association studies; Human genetics; Model organisms

Indexed keywords

4 AMINOBUTYRIC ACID; ACETYLCHOLINE; ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CYTOCHROME P450; DOPAMINE; GLUTAMIC ACID; OPIATE; SEROTONIN; ALCOHOL; MALATE DEHYDROGENASE;

ALCOHOL CONSUMPTION; ALCOHOL TOLERANCE; ALCOHOL WITHDRAWAL; ALCOHOLISM; ANIMAL BEHAVIOR; CANCER RISK; DRINKING BEHAVIOR; EXPERIMENTAL ANIMAL; GENE IDENTIFICATION; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENE OVEREXPRESSION; GENE REGULATORY NETWORK; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; MUTAGENESIS; NEUROTRANSMITTER RELEASE; NONHUMAN; PHENOTYPIC VARIATION; QUANTITATIVE TRAIT LOCUS; REVIEW; RISK FACTOR; RNA INTERFERENCE; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; ANIMAL; DISEASE MODEL; DROSOPHILA; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MOUSE; PHENOTYPE;

ALCOHOLISM; ANIMALS; DISEASE MODELS, ANIMAL; DROSOPHILA; ETHANOL; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALATE DEHYDROGENASE; MICE; PHENOTYPE; QUANTITATIVE TRAIT LOCI;

EID: 84857125314     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/gb-2012-13-2-239     Document Type: Review

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