Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: Role of vitagenes

Immunity and Ageing

Volumn 10, Issue 1, 2013, Pages

  Cornelius, Carolin ^a   Trovato Salinaro, Angela ^a   Scuto, Maria ^a   Fronte, Vincenzo ^a   Cambria, Maria T ^a   Pennisi, Manuela ^a   Bella, Rita ^a   Milone, Pietro ^a   Graziano, Antonio ^a   Crupi, Rosalia ^b   Cuzzocrea, Salvatore ^b   Pennisi, Giovanni ^a   Calabrese, Vittorio ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF MESSINA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; SIRTUIN 1; SIRTUIN 2; THIOREDOXIN; UNCOUPLING PROTEIN 1;

AGED; ALZHEIMER DISEASE; ARTICLE; CELLULAR STRESS RESPONSE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE; MALE; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

EID: 84885524005     PISSN: None     EISSN: 17424933     Source Type: Journal    
DOI: 10.1186/1742-4933-10-41     Document Type: Article

References (58)

1. Ballard C, Gauthier S, Corbett A, Brayne C, Aarsland D, Jones E. Alzheimer's disease. Lancet 2011, 19:1019-1031.
2. Cummings JL, Cole G. Alzheimer disease. JAMA 2002, 287:2335-2338. 10.1001/jama.287.18.2335, 11988038.
3. Mayeux R, Stern Y. Epidemiology of Alzheimer disease. Cold Spring Harb Perspect Med 2012, 1:2-8.
4. Blennow K, De Leon MJ, Zetterberg H. Alzheimer's disease. Lancet 2006, 29:387-403.
5. Gandy S. The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease. J Clin Invest 2005, 115:1121-1129. 1087184, 15864339.
6. Iqbal K, Alonso Adel C, Chen S, Chohan MO, El-Akkad E, Gong CX, Khatoon S, Li B, Liu F, Rahman A, Tanimukai H, Grundke-Iqbal I. Tau pathology in Alzheimer disease and other tauopathies. Biochim Biophys Acta 2005, 3 1739(2-3):198-210.
7. Katzman R, Saitoh T. Advances in Alzheimer's disease. FASEB J 1991, 5:278-286.
8. Keller JN, Hanni KB, Markesbery WR. Impaired proteasome function in Alzheimer's disease. J Neurochem 2000, 75:436-439.
9. Perry G, Friedman R, Shaw G, Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc Natl Acad Sci USA 1987, 84:3033-3036. 10.1073/pnas.84.9.3033, 304795, 3033674.
10. Holscher C. Development of beta-amyloid-induced neurodegeneration in Alzheimer's disease and novel neuroprotective strategies. Rev Neurosci 2005, 16:181-212.
11. Dumont M, Wille E, Stack C, Calingasan NY, Beal MF, Lin MT. Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease. FASEB J 2009, 23:2459-2466. 10.1096/fj.09-132928, 2717785, 19346295.
12. Maarten E, Witte John GJM, Bol Wouter H, Gerritsen P, van der Valk B, Drukarch J, Van Horssen M, Wilhelmus MM. Parkinson's disease-associated parkin colocalizes with Alzheimer's disease and multiple sclerosis brain lesions. Neurobiol Dis 2009, 15:1150-1161.
13. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease. Neurology 1984, 34:939-944. 10.1212/WNL.34.7.939, 6610841.
14. Butterfield DA, Drake J, Pocernich C, Castegna A. Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptid. Trends Mol Med 2001, 7:548-554. 10.1016/S1471-4914(01)02173-6, 11733217.
15. Calabrese V, Scapagnini G, Giuffrida Stella AM, Bates TE, Clark JB. Mitochondrial involvement in brain function and dysfunction: relevance to aging, neurodegenerative disorders and longevity. Neurochem Res 2001, 26:739-764. 10.1023/A:1010955807739, 11519733.
16. Calabrese V, Guagliano E, Sapienza M, Panebianco M, Calafato S, Puleo E. Redox regulation of cellular stress response in aging and neurodegenerative disorders: role of Vitagenes. Neurochem Res 2007, 32:757-773. 10.1007/s11064-006-9203-y, 17191135.
17. Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F. Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochem Res 2008, 33:2444-2471. 10.1007/s11064-008-9775-9, 18629638.
18. Calabrese V, Mancuso C, Calvani M, Rizzarelli E, Butterfield DA, Giuffrida Stella AM. Nitric oxide in the CNS: neuroprotection versus neurotoxicity. Nat Neurosci 2007, 8:766-775.
19. Calabrese V, Cornelius C, Stella AM, Calabrese EJ. Cellular stress responses, mitostress and carnitine insufficiencies as critical determinants in aging and neurodegenerative disorders: role of hormesis and vitagenes. Neurochem Res 2010, 35:1880-1915. 10.1007/s11064-010-0307-z, 21080068.
20. Dali-Youcef N, Lagouge M, Froelich S, Koehl C, Schoonjans K, Auwerx J. Sirtuins: the "magnificent seven", function, metabolism and longevity. Ann Med 2007, 39:335-345. 10.1080/07853890701408194, 17701476.
21. Calabrese V, Bates TE, Giuffrida Stella AM. NO synthase and NO-dependent signal pathways in brain aging and neurodegenerative disorders: the role of oxidant/antioxidant balance. Neurochem Res 2000, 65:1315-1341.
22. Calabrese V, Scapagnini G, Ravagna A, Giuffrida Stella AM, Butterfield DA. Molecular chaperones and their roles in neural cell differentiation. Dev Neurosci 2002, 24:1-13. 10.1159/000064941, 12145406.
23. Calabrese V, Guagliano E, Sapienza M, Mancuso C, Butterfield DA, Stella AM. Redox regulation of cellular stress response in neurodegenerative disorders. Ital J Biochem 2006, 55:263-282.
24. Calabrese V, Cornelius C, Dinkova-Kostova AT, Calabrese EJ, Mattson MP. Cellular stress responses, the hormesis paradigm, and Vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders. Antioxid Redox Signal 2010, 13:1763-1811. 10.1089/ars.2009.3074, 2966482, 20446769.
25. Holmgren A. Thioredoxin. Ann Rev Biochem 1985, 54:237-271. 10.1146/annurev.bi.54.070185.001321, 3896121.
26. Kathryn F, Di Trapani T, Di Trapani G. Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy. Mol Nutr Food Res 2009, 53:87-103. 10.1002/mnfr.200700492, 18979503.
27. Arsenijevic D, Onuma H, Pecqueur C, Raimbault S, Manning BS, Miroux B, Couplan E, Alves-Guerra MC, Goubern M, Surwit R, Bouillaud F, Richard D, Collins S, Ricquier DD. Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet 2000, 26:435-439. 10.1038/82565, 11101840.
28. Vidal-Puig AJ, Grujic D, Zhang CY, Hagen T, Boss O, Ido Y, Szczepanik A, Wade J, Mootha V, Cortright R, Muoio DM, Lowell BB. Energy metabolism in uncoupling protein 3 gene knockout mice. J Biol Chem 2000, 275:16258-16266. 10.1074/jbc.M910179199, 10748196.
29. Smith P, Krohn R, Hermanson G, Mallia A, Gartner F, Provenzano M. Measurement of proteins using bicinchoninic acid. Ann Biochem 1985, 150:76-85.
30. Glenner GG, Wong CW. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun 1984, 120:885-890. 10.1016/S0006-291X(84)80190-4, 6375662.
31. Lee VM, Balin BJ, Otvos JL, Trojanowski JQ. A 68: a major subunit of paired helical filaments and derivatized forms of normal Tau. Science 1991, 251:675-678. 10.1126/science.1899488, 1899488.
32. Selkoe DJ. The molecular pathology of Alzheimer's disease. Neuron 1991, 6:487-498. 10.1016/0896-6273(91)90052-2, 1673054.
33. Calabrese V, Butterfield DA, Scapagnini G, Stella AM, Maines MD. Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity. Antioxid Redox Signal 2006, 8:444-477. 10.1089/ars.2006.8.444, 16677090.
34. Calabrese V, Boyd-Kimball D, Scapagnini G, Butterfield DA. Nitric oxide and cellular stress response in brain aging and neurodegenerative disorders: the role of Vitagenes. In Vivo 2004, 18:245-267.
35. Mancuso C, Scapagnini G, Curro D, Giuffrida Stella AM, De Marco C, Butterfield DA. Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders. Front Biosci 2007, 12:1107-1123. 10.2741/2130, 17127365.
36. Butterfield DA, Lauderback CM. Lipid peroxidation and protein oxidation in Alzheimer's disease brain: potential causes and consequences involving amyloid beta-peptide-associated free radical oxidative stress. Free Radic Biol Med 2002, 32:1050-1060. 10.1016/S0891-5849(02)00794-3, 12031889.
37. Lauderback CM, Hackett JM, Huang FF, Keller JN, Szweda LI, Markesbery WR, Butterfield DA. The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42. J Neurochem 2001, 78:413-416. 10.1046/j.1471-4159.2001.00451.x, 11461977.
38. Bloomfield KL, Osborne SA, Kennedy DD, Clarke FM, Tonissen KF. Thioredoxin-mediated redox control of the transcription factor Sp1 and regulation of the thioredoxin gene promoter. Gene 2003, 319:107-116.
39. Bonda DJ, Lee HG, Camins A, Pallàs M, Casadesus G, Smith MA, Zhu X. The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic consideration. Lancet Neurol 2011, 10:275-279. 10.1016/S1474-4422(11)70013-8, 3163839, 21349442.
40. Boyd-Kimball D, Sultana R, Mohammad-Abdul H, Butterfield DA. Rodent Abeta (1-42) exhibits oxidative stress properties similar to those of human Abeta (1-42): implications for roposed mechanisms of toxicity. J Alzheimers Dis 2004, 6:515-525.
41. Boyd-Kimball D, Castegna A, Sultana R, Poon HF, Petroze R, Lynn BC, Klein JB, Butterfield DA. Proteomic identification of proteins oxidized by Aβ(1-42) in synaptosomes: implications for Alzheimer's disease. Brain Res 2005, 1044:206-215. 10.1016/j.brainres.2005.02.086, 15885219.
42. Boyd-Kimball D, Poon HF, Lynn BC, Cai J, Pierce WM, Klein JB, Ferguson J, Link CD, Butterfield DA. Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Aβ 1-42): implications for Alzheimer's disease. Neurobiol Aging 2006, 27:1239-1249. 10.1016/j.neurobiolaging.2005.07.001, 16099075.
43. Butterfield DA, Griffin S, Munch G, Pasinetti GM. Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists. J Alzheimers Dis 2002, 4:193-201.
44. Butterfield DA, Poon HF, Clair D, Keller JN, Pierce WM, Klein JB, Markesbery WR. Redox proteomics identification of oxidatively modified hippocampal proteins in mild cognitive impairment: insights into the development of Alzheimers disease. Neurobiol Dis 2006, 22:223-232. 10.1016/j.nbd.2005.11.002, 16466929.
45. Calabrese V, Sultana R, Scapagnini G, Guagliano E, Sapienza M, Bella R, Kanski J, Pennisi G, Mancuso C, Stella AM, Butterfield DA. Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease. Antioxid Redox Signal 2006, 8:1975-1986. 10.1089/ars.2006.8.1975, 17034343.
46. Calabrese V, Butterfield DA, Stella AM. Aging and oxidative stress response in the CNS. Neurochem Mol Neurobiol 2008, 23:128-234.
47. De la Monte SM, Wands JR. Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease. J Alzheimers Dis 2006, 9:167-181.
48. Drake J, Link CD, Butterfield DA. Oxidative stress precedes fibrillar deposition of Alzheimer's disease amyloid beta-peptide (1-42) in a transgenic Caenorhabditis elegans model. Neurobiol Aging 2003, 24:415-420. 10.1016/S0197-4580(02)00225-7, 12600717.
49. Herranz D, Serrano M. SIRT1: recent lessons from mouse models. Nat Rev Cancer 2010, 10:819-823. 10.1038/nrc2962, 3672967, 21102633.
50. Hirota K, Nakamura H, Masutani H, Yodoi J. Thioredoxin superfamily and thioredoxin-inducing agents. Ann NY Acad Sci 2002, 957:189-199. 10.1111/j.1749-6632.2002.tb02916.x, 12074972.
51. Keller JN, Schmitt FA, Scheff SW, Ding Q, Chen Q, Butterfield DA, Markesbery WR. Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology 2005, 64:1152-1156. 10.1212/01.WNL.0000156156.13641.BA, 15824339.
52. Nguyen T, Nioi P, Pickett CB. The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress. J Biol Chem 2009, 284:13291-13299. 10.1074/jbc.R900010200, 2679427, 19182219.
53. Vauzour D, Buonfiglio M, Corona G, Chirafisi J, Vafeiadou K, Angeloni C, Hrelia S, Hrelia P, Spencer SP. Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes. Mol Nutr Food Res 2010, 54:532-542. 10.1002/mnfr.200900197, 20166144.
54. Salminen A, Kauppinen A, Suuronen T, Kaarniranta K. SIRT1 longevity factor suppresses NF-kappaB-driven immune responses: regulation of aging via NF-kappaB acetylation?. Bioessays 2008, 30:939-942. 10.1002/bies.20799, 18800364.
55. Tanaka T, Nakamura H, Nishiyama A, Hosoi F, Masutani H, Wada H, Yodoi J. Redox regulation by thioredoxin superfamily: protection against oxidative stress and aging. Free Radic Res 2000, 33:851-855. 10.1080/10715760000301361, 11237106.
56. Yi J, Luo J. SIRT1 and p53, effect on cancer, senescence and beyond. Biochim Biophys Acta 2010, 1804:1684-1689. 10.1016/j.bbapap.2010.05.002, 2989880, 20471503.
57. Prozorovski T, Schulze-Topphoff U, Glumm R, Baumgart J, Schröter F, Ninnemann O. Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat Cell Biol 2008, 10:385-394. 10.1038/ncb1700, 18344989.
58. Nishiyama A, Masutani H, Nakamura H, Nishinaka Y, Yodoi J. Redox regulation by thioredoxin and thioredoxin-binding proteins. IUBMB Life 2001, 52:29-33. 10.1080/15216540252774739, 11795589.