ZnO-mediated regioselective C-arylsulfonylation of indoles: A facile solvent-free synthesis of 2- and 3-sulfonylindoles and preliminary evaluation of their activity against drug-resistant mutant HIV-1 reverse transcriptases (RTs)

Tetrahedron Letters

Volumn 54, Issue 46, 2013, Pages 6237-6241

  Tocco, Graziella ^a   Begala, Michela ^a   Esposito, Francesca ^a   Caboni, Pierluigi ^a   Cannas, Valeria ^a   Tramontano, Enzo ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

Author keywords

C Arylfonylation; HIV 1 RT; Indoles; Non nucleoside inhibitor; Regioselectivity

Indexed keywords

2 SULFONYLINDOLE DERIVATIVE; 3 SULFONYLINDOLE DERIVATIVE; INDOLE DERIVATIVE; MUTANT PROTEIN; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; ZINC OXIDE;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; ONE POT SYNTHESIS; STEREOCHEMISTRY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84885482045     PISSN: 00404039     EISSN: 18733581     Source Type: Journal    
DOI: 10.1016/j.tetlet.2013.09.017     Document Type: Article

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