메뉴 건너뛰기




Volumn 191, Issue 8, 2013, Pages 4288-4298

Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; GAMMA INTERFERON; GASTROINTESTINAL MUCOSA PROTECTIVE AGENT; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; MARESIN 1; MESSENGER RNA; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84885465373     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202743     Document Type: Article
Times cited : (172)

References (75)
  • 1
    • 30044449982 scopus 로고    scopus 로고
    • Resolution of inflammation: The beginning programs the end
    • Serhan, C. N., and J. Savill. 2005. Resolution of inflammation: the beginning programs the end. Nat. Immunol. 6: 1191-1197.
    • (2005) Nat. Immunol. , vol.6 , pp. 1191-1197
    • Serhan, C.N.1    Savill, J.2
  • 4
    • 41749090254 scopus 로고    scopus 로고
    • Anti-inflammatory and proresolving lipid mediators
    • Serhan, C. N., S. Yacoubian, and R. Yang. 2008. Anti-inflammatory and proresolving lipid mediators. Annu. Rev. Pathol. 3: 279-312.
    • (2008) Annu. Rev. Pathol. , vol.3 , pp. 279-312
    • Serhan, C.N.1    Yacoubian, S.2    Yang, R.3
  • 5
    • 0037152160 scopus 로고    scopus 로고
    • Resolvins: A family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
    • Serhan, C. N., S. Hong, K. Gronert, S. P. Colgan, P. R. Devchand, G. Mirick, and R. L. Moussignac. 2002. Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals. J. Exp. Med. 196: 1025-1037.
    • (2002) J. Exp. Med. , vol.196 , pp. 1025-1037
    • Serhan, C.N.1    Hong, S.2    Gronert, K.3    Colgan, S.P.4    Devchand, P.R.5    Mirick, G.6    Moussignac, R.L.7
  • 6
    • 0037180812 scopus 로고    scopus 로고
    • Points of control in inflammation
    • Nathan, C. 2002. Points of control in inflammation. Nature 420: 846-852.
    • (2002) Nature , vol.420 , pp. 846-852
    • Nathan, C.1
  • 7
    • 0032519925 scopus 로고    scopus 로고
    • Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-b, PGE2, and PAF
    • Fadok, V. A., D. L. Bratton, A. Konowal, P. W. Freed, J. Y. Westcott, and P. M. Henson. 1998. Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-b, PGE2, and PAF. J. Clin. Invest. 101: 890-898.
    • (1998) J. Clin. Invest. , vol.101 , pp. 890-898
    • Fadok, V.A.1    Bratton, D.L.2    Konowal, A.3    Freed, P.W.4    Westcott, J.Y.5    Henson, P.M.6
  • 8
    • 60749121730 scopus 로고    scopus 로고
    • Dietary n-6 and n-3 polyunsaturated fatty acids: From biochemistry to clinical implications in cardiovascular prevention
    • Russo, G. L. 2009. Dietary n-6 and n-3 polyunsaturated fatty acids: from biochemistry to clinical implications in cardiovascular prevention. Biochem. Pharmacol. 77: 937-946.
    • (2009) Biochem. Pharmacol. , vol.77 , pp. 937-946
    • Russo, G.L.1
  • 9
    • 2942545915 scopus 로고    scopus 로고
    • Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirintriggered endogenous epimers: An overview of their protective roles in catabasis
    • Serhan, C. N., K. Gotlinger, S. Hong, and M. Arita. 2004. Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirintriggered endogenous epimers: an overview of their protective roles in catabasis. Prostaglandins Other Lipid Mediat. 73: 155-172.
    • (2004) Prostaglandins Other Lipid Mediat. , vol.73 , pp. 155-172
    • Serhan, C.N.1    Gotlinger, K.2    Hong, S.3    Arita, M.4
  • 12
    • 84879629605 scopus 로고    scopus 로고
    • The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype
    • Dalli, J., M. Zhu, N. A. Vlasenko, B. Deng, J. Z. Haeggstrom, N. A. Petasis, and C. N. Serhan. 2013. The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype. FASEB J. 27: 2573-2583.
    • (2013) FASEB J. , vol.27 , pp. 2573-2583
    • Dalli, J.1    Zhu, M.2    Vlasenko, N.A.3    Deng, B.4    Haeggstrom, J.Z.5    Petasis, N.A.6    Serhan, C.N.7
  • 15
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • Maloy, K. J., and F. Powrie. 2011. Intestinal homeostasis and its breakdown in inflammatory bowel disease. Nature 474: 298-306.
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 16
    • 77649086402 scopus 로고    scopus 로고
    • Immune adaptations that maintain homeostasis with the intestinal microbiota
    • Hooper, L. V., and A. J. Macpherson. 2010. Immune adaptations that maintain homeostasis with the intestinal microbiota. Nat. Rev. Immunol. 10: 159-169.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 159-169
    • Hooper, L.V.1    Macpherson, A.J.2
  • 17
    • 34248136828 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Cause and immunobiology
    • Baumgart, D. C., and S. R. Carding. 2007. Inflammatory bowel disease: cause and immunobiology. Lancet 369: 1627-1640.
    • (2007) Lancet , vol.369 , pp. 1627-1640
    • Baumgart, D.C.1    Carding, S.R.2
  • 19
    • 80051922251 scopus 로고    scopus 로고
    • Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice
    • Bento, A. F., R. F. Claudino, R. C. Dutra, R. Marcon, and J. B. Calixto. 2011. Omega-3 fatty acid-derived mediators 17(R)-hydroxy docosahexaenoic acid, aspirin-triggered resolvin D1 and resolvin D2 prevent experimental colitis in mice. J. Immunol. 187: 1957-1969.
    • (2011) J. Immunol. , vol.187 , pp. 1957-1969
    • Bento, A.F.1    Claudino, R.F.2    Dutra, R.C.3    Marcon, R.4    Calixto, J.B.5
  • 21
    • 19644369581 scopus 로고    scopus 로고
    • Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis
    • Arita, M., M. Yoshida, S. Hong, E. Tjonahen, J. N. Glickman, N. A. Petasis, R. S. Blumberg, and C. N. Serhan. 2005. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis. Proc. Natl. Acad. Sci. USA 102: 7671-7676.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 7671-7676
    • Arita, M.1    Yoshida, M.2    Hong, S.3    Tjonahen, E.4    Glickman, J.N.5    Petasis, N.A.6    Blumberg, R.S.7    Serhan, C.N.8
  • 22
    • 84868462865 scopus 로고    scopus 로고
    • Evaluation of chemical mediators and cellular response during acute and chronic gut inflammatory response induced by dextran sodium sulfate in mice
    • Bento, A. F., D. F. Leite, R. Marcon, R. F. Claudino, R. C. Dutra, M. Cola, A. C. Martini, and J. B. Calixto. 2012. Evaluation of chemical mediators and cellular response during acute and chronic gut inflammatory response induced by dextran sodium sulfate in mice. Biochem. Pharmacol. 84: 1459-1469.
    • (2012) Biochem. Pharmacol. , vol.84 , pp. 1459-1469
    • Bento, A.F.1    Leite, D.F.2    Marcon, R.3    Claudino, R.F.4    Dutra, R.C.5    Cola, M.6    Martini, A.C.7    Calixto, J.B.8
  • 23
    • 45749136704 scopus 로고    scopus 로고
    • Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression
    • Ghia, J. E., P. Blennerhassett, and S. M. Collins. 2008. Impaired parasympathetic function increases susceptibility to inflammatory bowel disease in a mouse model of depression. J. Clin. Invest. 118: 2209-2218.
    • (2008) J. Clin. Invest. , vol.118 , pp. 2209-2218
    • Ghia, J.E.1    Blennerhassett, P.2    Collins, S.M.3
  • 24
    • 11144255122 scopus 로고    scopus 로고
    • Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice
    • Kimball, E. S., N. H.Wallace, C. R. Schneider, M. R. D'Andrea, and P. J. Hornby. 2004. Vanilloid receptor 1 antagonists attenuate disease severity in dextran sulphate sodium-induced colitis in mice. Neurogastroenterol. Motil. 16: 811-818.
    • (2004) Neurogastroenterol. Motil. , vol.16 , pp. 811-818
    • Kimball, E.S.1    Wallace, N.H.2    Schneider, C.R.3    D'Andrea, M.R.4    Hornby, P.J.5
  • 25
    • 0024584951 scopus 로고
    • Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease
    • Wallace, J. L., W. K. MacNaughton, G. P. Morris, and P. L. Beck. 1989. Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease. Gastroenterology 96: 29-36.
    • (1989) Gastroenterology , vol.96 , pp. 29-36
    • Wallace, J.L.1    Macnaughton, W.K.2    Morris, G.P.3    Beck, P.L.4
  • 27
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • Neurath, M. F., I. Fuss, B. L. Kelsall, E. Stüber, andW. Strober. 1995. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J. Exp. Med. 182: 1281-1290.
    • (1995) J. Exp. Med. , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Stüber, E.4    Strober, W.5
  • 28
    • 54249146562 scopus 로고    scopus 로고
    • The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice
    • Bento, A. F., D. F. Leite, R. F. Claudino, D. B. Hara, P. C. Leal, and J. B. Calixto. 2008. The selective nonpeptide CXCR2 antagonist SB225002 ameliorates acute experimental colitis in mice. J. Leukoc. Biol. 84: 1213-1221.
    • (2008) J. Leukoc. Biol. , vol.84 , pp. 1213-1221
    • Bento, A.F.1    Leite, D.F.2    Claudino, R.F.3    Hara, D.B.4    Leal, P.C.5    Calixto, J.B.6
  • 29
    • 0033378192 scopus 로고    scopus 로고
    • Isolation of neutrophil precursors from bone marrow for biochemical and transcriptional analysis
    • Cowland, J. B., and N. Borregaard. 1999. Isolation of neutrophil precursors from bone marrow for biochemical and transcriptional analysis. J. Immunol. Methods 232: 191-200.
    • (1999) J. Immunol. Methods , vol.232 , pp. 191-200
    • Cowland, J.B.1    Borregaard, N.2
  • 30
    • 0026643574 scopus 로고
    • Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor
    • Rao, K. M., J. Padmanabhan, D. L. Kilby, H. J. Cohen, M. S. Currie, and J. B. Weinberg. 1992. Flow cytometric analysis of nitric oxide production in human neutrophils using dichlorofluorescein diacetate in the presence of a calmodulin inhibitor. J. Leukoc. Biol. 51: 496-500.
    • (1992) J. Leukoc. Biol. , vol.51 , pp. 496-500
    • Rao, K.M.1    Padmanabhan, J.2    Kilby, D.L.3    Cohen, H.J.4    Currie, M.S.5    Weinberg, J.B.6
  • 31
    • 29244444522 scopus 로고    scopus 로고
    • Fluorescence probes used for detection of reactive oxygen species
    • Gomes, A., E. Fernandes, and J. L. Lima. 2005. Fluorescence probes used for detection of reactive oxygen species. J. Biochem. Biophys. Methods 65: 45-80.
    • (2005) J. Biochem. Biophys. Methods , vol.65 , pp. 45-80
    • Gomes, A.1    Fernandes, E.2    Lima, J.L.3
  • 32
    • 0030628362 scopus 로고    scopus 로고
    • Murine bone marrow-derived macrophages
    • Stanley, E. R. 1997. Murine bone marrow-derived macrophages. Methods Mol. Biol. 75: 301-304.
    • (1997) Methods Mol. Biol. , vol.75 , pp. 301-304
    • Stanley, E.R.1
  • 34
    • 2142811722 scopus 로고    scopus 로고
    • The inflammatory infiltrate in the acute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it
    • Stevceva, L., P. Pavli, A. J. Husband, and W. F. Doe. 2001. The inflammatory infiltrate in the acute stage of the dextran sulphate sodium induced colitis: B cell response differs depending on the percentage of DSS used to induce it. BMC Clin. Pathol. 1: 3.
    • (2001) BMC Clin. Pathol. , vol.1 , pp. 3
    • Stevceva, L.1    Pavli, P.2    Husband, A.J.3    Doe, W.F.4
  • 36
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Abraham, C., and J. H. Cho. 2009. Inflammatory bowel disease. N. Engl. J. Med. 361: 2066-2078.
    • (2009) N. Engl. J. Med. , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.H.2
  • 37
    • 27644498849 scopus 로고    scopus 로고
    • Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation
    • Ledeboer, A., M. Gamanos, W. Lai, D. Martin, S. F. Maier, L. R. Watkins, and N. Quan. 2005. Involvement of spinal cord nuclear factor kappaB activation in rat models of proinflammatory cytokine-mediated pain facilitation. Eur. J. Neurosci. 22: 1977-1986.
    • (2005) Eur. J. Neurosci. , vol.22 , pp. 1977-1986
    • Ledeboer, A.1    Gamanos, M.2    Lai, W.3    Martin, D.4    Maier, S.F.5    Watkins, L.R.6    Quan, N.7
  • 38
    • 0031434763 scopus 로고    scopus 로고
    • Predominant role of NF-kB p65 in the pathogenesis of chronic intestinal inflammation
    • Neurath, M. F., and S. Pettersson. 1997. Predominant role of NF-kB p65 in the pathogenesis of chronic intestinal inflammation. Immunobiology 198: 91-98.
    • (1997) Immunobiology , vol.198 , pp. 91-98
    • Neurath, M.F.1    Pettersson, S.2
  • 40
    • 84875442814 scopus 로고    scopus 로고
    • Neutrophil recruitment and function in health and inflammation
    • Kolaczkowska, E., and P. Kubes. 2013. Neutrophil recruitment and function in health and inflammation. Nat. Rev. Immunol. 13: 159-175.
    • (2013) Nat. Rev. Immunol. , vol.13 , pp. 159-175
    • Kolaczkowska, E.1    Kubes, P.2
  • 41
    • 84864861276 scopus 로고    scopus 로고
    • The role of neutrophils during intestinal inflammation
    • Fournier, B. M., and C. A. Parkos. 2012. The role of neutrophils during intestinal inflammation. Mucosal Immunol. 5: 354-366.
    • (2012) Mucosal Immunol. , vol.5 , pp. 354-366
    • Fournier, B.M.1    Parkos, C.A.2
  • 43
    • 63849209890 scopus 로고    scopus 로고
    • Therapeutic effect of blocking CXCR2 on neutrophil recruitment and dextran sodium sulfate-induced colitis
    • Farooq, S. M., R. Stillie, M. Svensson, C. Svanborg, R. M. Strieter, and A. W. Stadnyk. 2009. Therapeutic effect of blocking CXCR2 on neutrophil recruitment and dextran sodium sulfate-induced colitis. J. Pharmacol. Exp. Ther. 329: 123-129.
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 123-129
    • Farooq, S.M.1    Stillie, R.2    Svensson, M.3    Svanborg, C.4    Strieter, R.M.5    Stadnyk, A.W.6
  • 44
    • 84881026932 scopus 로고    scopus 로고
    • Living and dying for inflammation: Neutrophils, eosinophils, basophils
    • Geering, B., C. Stoeckle, S. Conus, and H. U. Simon. 2013. Living and dying for inflammation: neutrophils, eosinophils, basophils. Trends Immunol. 34: 398-409.
    • (2013) Trends Immunol. , vol.34 , pp. 398-409
    • Geering, B.1    Stoeckle, C.2    Conus, S.3    Simon, H.U.4
  • 45
    • 63849206740 scopus 로고    scopus 로고
    • NADPH oxidase activity: In the crossroad of neutrophil life and death
    • Arruda, M. A., and C. Barja-Fidalgo. 2009. NADPH oxidase activity: In the crossroad of neutrophil life and death. Front. Biosci. (Landmark Ed.) 14: 4546-4556.
    • (2009) Front. Biosci. (Landmark Ed.) , vol.14 , pp. 4546-4556
    • Arruda, M.A.1    Barja-Fidalgo, C.2
  • 46
    • 72949116358 scopus 로고    scopus 로고
    • Macrophage death and defective inflammation resolution in atherosclerosis
    • Tabas, I. 2010. Macrophage death and defective inflammation resolution in atherosclerosis. Nat. Rev. Immunol. 10: 36-46.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 36-46
    • Tabas, I.1
  • 48
    • 38449103815 scopus 로고    scopus 로고
    • The role of dendritic cells in the development of acute dextran sulfate sodium colitis
    • Berndt, B. E., M. Zhang, G. H. Chen, G. B. Huffnagle, and J. Y. Kao. 2007. The role of dendritic cells in the development of acute dextran sulfate sodium colitis. J. Immunol. 179: 6255-6262.
    • (2007) J. Immunol. , vol.179 , pp. 6255-6262
    • Berndt, B.E.1    Zhang, M.2    Chen, G.H.3    Huffnagle, G.B.4    Kao, J.Y.5
  • 49
    • 0028290699 scopus 로고
    • Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis
    • Ferretti, M., V. Casini-Raggi, T. T. Pizarro, S. P. Eisenberg, C. C. Nast, and F. Cominelli. 1994. Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitis. J. Clin. Invest. 94: 449-453.
    • (1994) J. Clin. Invest. , vol.94 , pp. 449-453
    • Ferretti, M.1    Casini-Raggi, V.2    Pizarro, T.T.3    Eisenberg, S.P.4    Nast, C.C.5    Cominelli, F.6
  • 50
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
    • Martinez, F. O., S. Gordon, M. Locati, and A. Mantovani. 2006. Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 177: 7303-7311.
    • (2006) J. Immunol. , vol.177 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 51
    • 33947594914 scopus 로고    scopus 로고
    • Pharmacological and biochemical characterization of bradykinin B2 receptors in the mouse colon: Influence of the TNBS-induced colitis
    • Hara, D. B., E. S. Fernandes, M. M. Campos, and J. B. Calixto. 2007. Pharmacological and biochemical characterization of bradykinin B2 receptors in the mouse colon: influence of the TNBS-induced colitis. Regul. Pept. 141: 25-34.
    • (2007) Regul. Pept. , vol.141 , pp. 25-34
    • Hara, D.B.1    Fernandes, E.S.2    Campos, M.M.3    Calixto, J.B.4
  • 52
    • 84861109303 scopus 로고    scopus 로고
    • Omega-3 fatty acids and inflammatory bowel diseases: A systematic review
    • Cabré, E., M. Mañosa, and M. A. Gassull. 2012. Omega-3 fatty acids and inflammatory bowel diseases: a systematic review. Br. J. Nutr. 107(Suppl. 2): S240-S252.
    • (2012) Br. J. Nutr. , vol.107 , Issue.SUPPL. 2
    • Cabré, E.1    Mañosa, M.2    Gassull, M.A.3
  • 53
    • 79551547367 scopus 로고    scopus 로고
    • Oral administration of docosahexaenoic acid attenuates colitis induced by dextran sulfate sodium in mice
    • Cho, J. Y., S. G. Chi, and H. S. Chun. 2011. Oral administration of docosahexaenoic acid attenuates colitis induced by dextran sulfate sodium in mice. Mol. Nutr. Food Res. 55: 239-246.
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 239-246
    • Cho, J.Y.1    Chi, S.G.2    Chun, H.S.3
  • 54
    • 34147146340 scopus 로고    scopus 로고
    • The importance of fish and docosahexaenoic acid in Alzheimer disease
    • Connor, W. E., and S. L. Connor. 2007. The importance of fish and docosahexaenoic acid in Alzheimer disease. Am. J. Clin. Nutr. 85: 929-930.
    • (2007) Am. J. Clin. Nutr. , vol.85 , pp. 929-930
    • Connor, W.E.1    Connor, S.L.2
  • 55
    • 0025316221 scopus 로고
    • Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: Possible mechanisms
    • Kinsella, J. E., B. Lokesh, and R. A. Stone. 1990. Dietary n-3 polyunsaturated fatty acids and amelioration of cardiovascular disease: possible mechanisms. Am. J. Clin. Nutr. 52: 1-28.
    • (1990) Am. J. Clin. Nutr. , vol.52 , pp. 1-28
    • Kinsella, J.E.1    Lokesh, B.2    Stone, R.A.3
  • 56
    • 33751578868 scopus 로고    scopus 로고
    • Docosahexaenoic acid protects from amyloid and dendritic pathology in an Alzheimer's disease mouse model
    • Cole, G. M., and S. A. Frautschy. 2006. Docosahexaenoic acid protects from amyloid and dendritic pathology in an Alzheimer's disease mouse model. Nutr. Health 18: 249-259.
    • (2006) Nutr. Health , vol.18 , pp. 249-259
    • Cole, G.M.1    Frautschy, S.A.2
  • 58
    • 0034005581 scopus 로고    scopus 로고
    • Role of cytokines in the pathogenesis of inflammatory bowel disease
    • Papadakis, K. A., and S. R. Targan. 2000. Role of cytokines in the pathogenesis of inflammatory bowel disease. Annu. Rev. Med. 51: 289-298.
    • (2000) Annu. Rev. Med. , vol.51 , pp. 289-298
    • Papadakis, K.A.1    Targan, S.R.2
  • 59
    • 34548131585 scopus 로고    scopus 로고
    • The immune response in inflammatory bowel disease
    • Brown, S. J., and L. Mayer. 2007. The immune response in inflammatory bowel disease. Am. J. Gastroenterol. 102: 2058-2069.
    • (2007) Am. J. Gastroenterol. , vol.102 , pp. 2058-2069
    • Brown, S.J.1    Mayer, L.2
  • 61
    • 79954526916 scopus 로고    scopus 로고
    • What is the optimal therapy for severe ulcerative colitis?
    • MacDermott, R. P., J. A. Green, and C. C. Ashley. 2008. What is the optimal therapy for severe ulcerative colitis? Inflamm. Bowel Dis. 14(Suppl. 2): S228-S231.
    • (2008) Inflamm Bowel Dis. , vol.14 , Issue.SUPPL. 2
    • Macdermott, R.P.1    Green, J.A.2    Ashley, C.C.3
  • 63
    • 0037043658 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • Podolsky, D. K. 2002. Inflammatory bowel disease. N. Engl. J. Med. 347: 417-429.
    • (2002) N. Engl. J. Med. , vol.347 , pp. 417-429
    • Podolsky, D.K.1
  • 64
    • 33644875407 scopus 로고    scopus 로고
    • Adhesion molecules in inflammatory bowel disease: Therapeutic implications for gut inflammation
    • Danese, S., S. Semeraro, M. Marini, I. Roberto, A. Armuzzi, A. Papa, and A. Gasbarrini. 2005. Adhesion molecules in inflammatory bowel disease: therapeutic implications for gut inflammation. Dig. Liver Dis. 37: 811-818.
    • (2005) Dig. Liver Dis. , vol.37 , pp. 811-818
    • Danese, S.1    Semeraro, S.2    Marini, M.3    Roberto, I.4    Armuzzi, A.5    Papa, A.6    Gasbarrini, A.7
  • 68
    • 81455131791 scopus 로고    scopus 로고
    • Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype
    • Titos, E., B. Rius, A. González-Périz, C. López-Vicario, E. Morán-Salvador, M. Martínez-Clemente, V. Arroyo, and J. Clària. 2011. Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype. J. Immunol. 187: 5408-5418.
    • (2011) J. Immunol. , vol.187 , pp. 5408-5418
    • Titos, E.1    Rius, B.2    González-Périz, A.3    López-Vicario, C.4    Morán-Salvador, E.5    Martínez-Clemente, M.6    Arroyo, V.7    Clària, J.8
  • 69
    • 78650894319 scopus 로고    scopus 로고
    • Crosstalk of reactive oxygen species and NF-kB signaling
    • Morgan, M. J., and Z. G. Liu. 2011. Crosstalk of reactive oxygen species and NF-kB signaling. Cell Res. 21: 103-115.
    • (2011) Cell Res. , vol.21 , pp. 103-115
    • Morgan, M.J.1    Liu, Z.G.2
  • 70
    • 4544228457 scopus 로고    scopus 로고
    • Functions of NF-kB1 and NF-kB2 in immune cell biology
    • Beinke, S., and S. C. Ley. 2004. Functions of NF-kB1 and NF-kB2 in immune cell biology. Biochem. J. 382: 393-409.
    • (2004) Biochem. J. , vol.382 , pp. 393-409
    • Beinke, S.1    Ley, S.C.2
  • 72
    • 49749141035 scopus 로고    scopus 로고
    • Antiinflammatory properties of omega-3 fatty acids in critical illness: Novel mechanisms and an integrative perspective
    • Singer, P., H. Shapiro, M. Theilla, R. Anbar, J. Singer, and J. Cohen. 2008. Antiinflammatory properties of omega-3 fatty acids in critical illness: novel mechanisms and an integrative perspective. Intensive Care Med. 34: 1580-1592.
    • (2008) Intensive Care Med. , vol.34 , pp. 1580-1592
    • Singer, P.1    Shapiro, H.2    Theilla, M.3    Anbar, R.4    Singer, J.5    Cohen, J.6
  • 73
    • 67650485985 scopus 로고    scopus 로고
    • Alternative activation of macrophages: An immunologic functional perspective
    • Martinez, F. O., L. Helming, and S. Gordon. 2009. Alternative activation of macrophages: an immunologic functional perspective. Annu. Rev. Immunol. 27: 451-483.
    • (2009) Annu. Rev. Immunol. , vol.27 , pp. 451-483
    • Martinez, F.O.1    Helming, L.2    Gordon, S.3
  • 75
    • 74949124402 scopus 로고    scopus 로고
    • Editorial: Macrophage functional phenotypes: No alternatives in dermal wound healing?
    • Stout, R. D. 2010. Editorial: macrophage functional phenotypes: no alternatives in dermal wound healing? J. Leukoc. Biol. 87: 19-21.
    • (2010) J Leukoc. Biol. , vol.87 , pp. 19-21
    • Stout, R.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.