-
1
-
-
0036109159
-
Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections
-
Appay, V., P. R. Dunbar, M. Callan, P. Klenerman, G. M. Gillespie, L. Papagno, G. S. Ogg, A. King, F. Lechner, C. A. Spina, et al. 2002. Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat. Med. 8: 379-385.
-
(2002)
Nat. Med.
, vol.8
, pp. 379-385
-
-
Appay, V.1
Dunbar, P.R.2
Callan, M.3
Klenerman, P.4
Gillespie, G.M.5
Papagno, L.6
Ogg, G.S.7
King, A.8
Lechner, F.9
Spina, C.A.10
-
2
-
-
56449089734
-
The complex role of B7 molecules in tumor immunology
-
Seliger, B., F. M. Marincola, S. Ferrone, and H. Abken. 2008. The complex role of B7 molecules in tumor immunology. Trends Mol. Med. 14: 550-559.
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 550-559
-
-
Seliger, B.1
Marincola, F.M.2
Ferrone, S.3
Abken, H.4
-
3
-
-
79956077563
-
T cell exhaustion
-
Wherry, E. J. 2011. T cell exhaustion. Nat. Immunol. 12: 492-499.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 492-499
-
-
Wherry, E.J.1
-
4
-
-
84864324543
-
Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2
-
Yokosuka, T., M. Takamatsu, W. Kobayashi-Imanishi, A. Hashimoto-Tane, M. Azuma, and T. Saito. 2012. Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. J. Exp. Med. 209: 1201-1217.
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1201-1217
-
-
Yokosuka, T.1
Takamatsu, M.2
Kobayashi-Imanishi, W.3
Hashimoto-Tane, A.4
Azuma, M.5
Saito, T.6
-
5
-
-
5844264920
-
PD-L2 is a second ligand for PD-1 and inhibits T cell activation
-
Latchman, Y., C. R. Wood, T. Chernova, D. Chaudhary, M. Borde, I. Chernova, Y. Iwai, A. J. Long, J. A. Brown, R. Nunes, et al. 2001. PD-L2 is a second ligand for PD-1 and inhibits T cell activation. Nat. Immunol. 2: 261-268.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 261-268
-
-
Latchman, Y.1
Wood, C.R.2
Chernova, T.3
Chaudhary, D.4
Borde, M.5
Chernova, I.6
Iwai, Y.7
Long, A.J.8
Brown, J.A.9
Nunes, R.10
-
6
-
-
18544380239
-
Tumor-Associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong, H., S. E. Strome, D. R. Salomao, H. Tamura, F. Hirano, D. B. Flies, P. C. Roche, J. Lu, G. Zhu, K. Tamada, et al. 2002. Tumor-Associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med. 8: 793-800.
-
(2002)
Nat. Med.
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
Roche, P.C.7
Lu, J.8
Zhu, G.9
Tamada, K.10
-
7
-
-
33645736792
-
Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
-
Thompson, R. H., S. M. Kuntz, B. C. Leibovich, H. Dong, C. M. Lohse, W. S. Webster, S. Sengupta, I. Frank, A. S. Parker, H. Zincke, et al. 2006. Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up. Cancer Res. 66: 3381-3385.
-
(2006)
Cancer Res.
, vol.66
, pp. 3381-3385
-
-
Thompson, R.H.1
Kuntz, S.M.2
Leibovich, B.C.3
Dong, H.4
Lohse, C.M.5
Webster, W.S.6
Sengupta, S.7
Frank, I.8
Parker, A.S.9
Zincke, H.10
-
8
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir, M. E., M. J. Butte, G. J. Freeman, and A. H. Sharpe. 2008. PD-1 and its ligands in tolerance and immunity. Annu. Rev. Immunol. 26: 677-704.
-
(2008)
Annu. Rev. Immunol.
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
9
-
-
33748947326
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
-
Day, C. L., D. E. Kaufmann, P. Kiepiela, J. A. Brown, E. S. Moodley, S. Reddy, E. W. Mackey, J. D. Miller, A. J. Leslie, C. DePierres, et al. 2006. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443: 350-354.
-
(2006)
Nature
, vol.443
, pp. 350-354
-
-
Day, C.L.1
Kaufmann, D.E.2
Kiepiela, P.3
Brown, J.A.4
Moodley, E.S.5
Reddy, S.6
Mackey, E.W.7
Miller, J.D.8
Leslie, A.J.9
Depierres, C.10
-
10
-
-
32544459770
-
Restoring function in exhausted CD8 T cells during chronic viral infection
-
Barber, D. L., E. J. Wherry, D. Masopust, B. Zhu, J. P. Allison, A. H. Sharpe, G. J. Freeman, and R. Ahmed. 2006. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439: 682-687.
-
(2006)
Nature
, vol.439
, pp. 682-687
-
-
Barber, D.L.1
Wherry, E.J.2
Masopust, D.3
Zhu, B.4
Allison, J.P.5
Sharpe, A.H.6
Freeman, G.J.7
Ahmed, R.8
-
11
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian, S. L., F. S. Hodi, J. R. Brahmer, S. N. Gettinger, D. C. Smith, D. F. McDermott, J. D. Powderly, R. D. Carvajal, J. A. Sosman, M. B. Atkins, et al. 2012. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366: 2443-2454.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
-
13
-
-
79954459308
-
Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family
-
Bour-Jordan, H., J. H. Esensten, M. Martinez-Llordella, C. Penaranda, M. Stumpf, and J. A. Bluestone. 2011. Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/B7 family. Immunol. Rev. 241: 180-205.
-
(2011)
Immunol. Rev.
, vol.241
, pp. 180-205
-
-
Bour-Jordan, H.1
Esensten, J.H.2
Martinez-Llordella, M.3
Penaranda, C.4
Stumpf, M.5
Bluestone, J.A.6
-
14
-
-
80054850038
-
The TNF receptor super family in immune regulation
-
Ware, C. F. 2011. The TNF receptor super family in immune regulation. Immunol. Rev. 244: 5-8.
-
(2011)
Immunol. Rev.
, vol.244
, pp. 5-8
-
-
Ware, C.F.1
-
15
-
-
79953151458
-
Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
-
Schreiber, R. D., L. J. Old, and M. J. Smyth. 2011. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 331: 1565-1570.
-
(2011)
Science
, vol.331
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
16
-
-
84858758766
-
Adoptive immunotherapy for cancer: Harnessing the T cell response
-
Restifo, N. P., M. E. Dudley, and S. A. Rosenberg. 2012. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat. Rev. Immunol. 12: 269-281.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 269-281
-
-
Restifo, N.P.1
Dudley, M.E.2
Rosenberg, S.A.3
-
17
-
-
84874272015
-
How (specific) would like your T-cells today ? Generating T-cell therapeutic function through TCR-gene transfer
-
Daniel-Meshulam, I., S. Ya'akobi, C. Ankri, and C. J. Cohen. 2012. How (specific) would like your T-cells today ? Generating T-cell therapeutic function through TCR-gene transfer. Front. Immunol. 3: 186.
-
(2012)
Front. Immunol.
, vol.3
, pp. 186
-
-
Daniel-Meshulam, I.1
Ya'akobi, S.2
Ankri, C.3
Cohen, C.J.4
-
18
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan, R. A., M. E. Dudley, J. R. Wunderlich, M. S. Hughes, J. C. Yang, R. M. Sherry, R. E. Royal, S. L. Topalian, U. S. Kammula, N. P. Restifo, et al. 2006. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 314: 126-129.
-
(2006)
Science
, vol.314
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
Royal, R.E.7
Topalian, S.L.8
Kammula, U.S.9
Restifo, N.P.10
-
19
-
-
79952304769
-
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
-
Robbins, P. F., R. A. Morgan, S. A. Feldman, J. C. Yang, R. M. Sherry, M. E. Dudley, J. R. Wunderlich, A. V. Nahvi, L. J. Helman, C. L. Mackall, et al. 2011. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. J. Clin. Oncol. 29: 917-924.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 917-924
-
-
Robbins, P.F.1
Morgan, R.A.2
Feldman, S.A.3
Yang, J.C.4
Sherry, R.M.5
Dudley, M.E.6
Wunderlich, J.R.7
Nahvi, A.V.8
Helman, L.J.9
Mackall, C.L.10
-
21
-
-
0141449956
-
Restoration of CD28 expression in CD282 CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production
-
Topp, M. S., S. R. Riddell, Y. Akatsuka, M. C. Jensen, J. N. Blattman, and P. D. Greenberg. 2003. Restoration of CD28 expression in CD282 CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production. J. Exp. Med. 198: 947-955.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 947-955
-
-
Topp, M.S.1
Riddell, S.R.2
Akatsuka, Y.3
Jensen, M.C.4
Blattman, J.N.5
Greenberg, P.D.6
-
22
-
-
34848831575
-
The B7 family and cancer therapy: Costimulation and coinhibition
-
Zang, X., and J. P. Allison. 2007. The B7 family and cancer therapy: costimulation and coinhibition. Clin. Cancer Res. 13: 5271-5279.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 5271-5279
-
-
Zang, X.1
Allison, J.P.2
-
23
-
-
0024390061
-
Tumor-specific cytolysis by lymphocytes infiltrating human melanomas
-
Topalian, S. L., D. Solomon, and S. A. Rosenberg. 1989. Tumor-specific cytolysis by lymphocytes infiltrating human melanomas. J. Immunol. 142: 3714-3725.
-
(1989)
J. Immunol.
, vol.142
, pp. 3714-3725
-
-
Topalian, S.L.1
Solomon, D.2
Rosenberg, S.A.3
-
24
-
-
0023243241
-
Phenotypic heterogeneity of melanoma: Relation to the differentiation program of melanoma cells
-
Houghton, A. N., F. X. Real, L. J. Davis, C. Cordon-Cardo, and L. J. Old. 1987. Phenotypic heterogeneity of melanoma: relation to the differentiation program of melanoma cells. J. Exp. Med. 165: 812-829.
-
(1987)
J. Exp. Med.
, vol.165
, pp. 812-829
-
-
Houghton, A.N.1
Real, F.X.2
Davis, L.J.3
Cordon-Cardo, C.4
Old, L.J.5
-
25
-
-
27144435476
-
Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR
-
Cohen, C. J., Z. Zheng, R. Bray, Y. Zhao, L. A. Sherman, S. A. Rosenberg, and R. A. Morgan. 2005. Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR. J. Immunol. 175: 5799-5808.
-
(2005)
J. Immunol.
, vol.175
, pp. 5799-5808
-
-
Cohen, C.J.1
Zheng, Z.2
Bray, R.3
Zhao, Y.4
Sherman, L.A.5
Rosenberg, S.A.6
Morgan, R.A.7
-
26
-
-
58149291460
-
Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression
-
Wargo, J. A., P. F. Robbins, Y. Li, Y. Zhao, M. El-Gamil, D. Caragacianu, Z. Zheng, J. A. Hong, S. Downey, D. S. Schrump, et al. 2009. Recognition of NY-ESO-1+ tumor cells by engineered lymphocytes is enhanced by improved vector design and epigenetic modulation of tumor antigen expression. Cancer Immunol. Immunother. 58: 383-394.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 383-394
-
-
Wargo, J.A.1
Robbins, P.F.2
Li, Y.3
Zhao, Y.4
El-Gamil, M.5
Caragacianu, D.6
Zheng, Z.7
Hong, J.A.8
Downey, S.9
Schrump, D.S.10
-
27
-
-
20844448391
-
Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions
-
Hughes, M. S., Y. Y. Yu, M. E. Dudley, Z. Zheng, P. F. Robbins, Y. Li, J. Wunderlich, R. G. Hawley, M. Moayeri, S. A. Rosenberg, and R. A. Morgan. 2005. Transfer of a TCR gene derived from a patient with a marked antitumor response conveys highly active T-cell effector functions. Hum. Gene Ther. 16: 457-472.
-
(2005)
Hum. Gene Ther.
, vol.16
, pp. 457-472
-
-
Hughes, M.S.1
Yu, Y.Y.2
Dudley, M.E.3
Zheng, Z.4
Robbins, P.F.5
Li, Y.6
Wunderlich, J.7
Hawley, R.G.8
Moayeri, M.9
Rosenberg, S.A.10
Morgan, R.A.11
-
28
-
-
33749005425
-
Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability
-
Cohen, C. J., Y. Zhao, Z. Zheng, S. A. Rosenberg, and R. A. Morgan. 2006. Enhanced antitumor activity of murine-human hybrid T-cell receptor (TCR) in human lymphocytes is associated with improved pairing and TCR/CD3 stability. Cancer Res. 66: 8878-8886.
-
(2006)
Cancer Res.
, vol.66
, pp. 8878-8886
-
-
Cohen, C.J.1
Zhao, Y.2
Zheng, Z.3
Rosenberg, S.A.4
Morgan, R.A.5
-
29
-
-
28844442400
-
High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation
-
Zhao, Y., Z. Zheng, C. J. Cohen, L. Gattinoni, D. C. Palmer, N. P. Restifo, S. A. Rosenberg, and R. A. Morgan. 2006. High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation. Mol. Ther. 13: 151-159.
-
(2006)
Mol. Ther.
, vol.13
, pp. 151-159
-
-
Zhao, Y.1
Zheng, Z.2
Cohen, C.J.3
Gattinoni, L.4
Palmer, D.C.5
Restifo, N.P.6
Rosenberg, S.A.7
Morgan, R.A.8
-
30
-
-
77953458193
-
Selected murine residues endow human TCR with enhanced tumor recognition
-
Bialer, G., M. Horovitz-Fried, S. Ya'acobi, R. A. Morgan, and C. J. Cohen. 2010. Selected murine residues endow human TCR with enhanced tumor recognition. J. Immunol. 184: 6232-6241.
-
(2010)
J. Immunol.
, vol.184
, pp. 6232-6241
-
-
Bialer, G.1
Horovitz-Fried, M.2
Ya'acobi, S.3
Morgan, R.A.4
Cohen, C.J.5
-
31
-
-
84862077998
-
Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity
-
Haga-Friedman, A., M. Horovitz-Fried, and C. J. Cohen. 2012. Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity. J. Immunol. 188: 5538-5546.
-
(2012)
J. Immunol.
, vol.188
, pp. 5538-5546
-
-
Haga-Friedman, A.1
Horovitz-Fried, M.2
Cohen, C.J.3
-
32
-
-
0037829421
-
Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients
-
Dudley, M. E., J. R. Wunderlich, T. E. Shelton, J. Even, and S. A. Rosenberg. 2003. Generation of tumor-infiltrating lymphocyte cultures for use in adoptive transfer therapy for melanoma patients. J. Immunother. 26: 332-342.
-
(2003)
J. Immunother.
, vol.26
, pp. 332-342
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Shelton, T.E.3
Even, J.4
Rosenberg, S.A.5
-
33
-
-
0036000333
-
Clinical-scale selection of anti-CD3/CD28-Activated T cells after transduction with a retroviral vector expressing herpes simplex virus thymidine kinase and truncated nerve growth factor receptor
-
Orchard, P. J., B. R. Blazar, S. Burger, B. Levine, L. Basso, D. M. Nelson, K. Gordon, R. S. McIvor, J. E. Wagner, and J. S. Miller. 2002. Clinical-scale selection of anti-CD3/CD28-Activated T cells after transduction with a retroviral vector expressing herpes simplex virus thymidine kinase and truncated nerve growth factor receptor. Hum. Gene Ther. 13: 979-988.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 979-988
-
-
Orchard, P.J.1
Blazar, B.R.2
Burger, S.3
Levine, B.4
Basso, L.5
Nelson, D.M.6
Gordon, K.7
McIvor, R.S.8
Wagner, J.E.9
Miller, J.S.10
-
34
-
-
84863607641
-
Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition
-
Wilde, S., D. Sommermeyer, M. Leisegang, B. Frankenberger, B. Mosetter, W. Uckert, and D. J. Schendel. 2012. Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition. J. Immunol. 189: 598-605.
-
(2012)
J. Immunol.
, vol.189
, pp. 598-605
-
-
Wilde, S.1
Sommermeyer, D.2
Leisegang, M.3
Frankenberger, B.4
Mosetter, B.5
Uckert, W.6
Schendel, D.J.7
-
35
-
-
27644457376
-
TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
-
Thomas, D. A., and J. Massagué. 2005. TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 8: 369-380.
-
(2005)
Cancer Cell
, vol.8
, pp. 369-380
-
-
Thomas, D.A.1
Massagué, J.2
-
36
-
-
0025947446
-
B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2
-
Gimmi, C. D., G. J. Freeman, J. G. Gribben, K. Sugita, A. S. Freedman, C. Morimoto, and L. M. Nadler. 1991. B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2. Proc. Natl. Acad. Sci. USA 88: 6575-6579.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 6575-6579
-
-
Gimmi, C.D.1
Freeman, G.J.2
Gribben, J.G.3
Sugita, K.4
Freedman, A.S.5
Morimoto, C.6
Nadler, L.M.7
-
37
-
-
84887614931
-
PD-1 coinhibitory signals: The link between pathogenesis and protection
-
DOI: 10.1016/j.smim.2013.02.002
-
Kulpa, D. A., M. Lawani, A. Cooper, Y. Peretz, J. Ahlers, and R. P. Sékaly. 2013. PD-1 coinhibitory signals: the link between pathogenesis and protection. Semin. Immunol. DOI: 10.1016/j.smim.2013.02.002.
-
(2013)
Semin. Immunol.
-
-
Kulpa, D.A.1
Lawani, M.2
Cooper, A.3
Peretz, Y.4
Ahlers, J.5
Sékaly, R.P.6
-
38
-
-
84885668507
-
Enhanced antitumor activity mediated by human 4-1BB-engineered T cells
-
10.1002/ijc.28320
-
Daniel-Meshulam, I., M. Horovitz-Fried, and C. J. Cohen. 2013. Enhanced antitumor activity mediated by human 4-1BB-engineered T cells. Int. J. Cancer 10.1002/ijc.28320.
-
(2013)
Int. J. Cancer
-
-
Daniel-Meshulam, I.1
Horovitz-Fried, M.2
Cohen, C.J.3
-
39
-
-
0000970685
-
Transplantability of tissues to the embryo of foreign species: Its bearing on questions of tissue specificity and tumor immunity
-
Murphy, J. B. 1913. Transplantability of tissues to the embryo of foreign species: its bearing on questions of tissue specificity and tumor immunity. J. Exp. Med. 17: 482-493.
-
(1913)
J. Exp. Med.
, vol.17
, pp. 482-493
-
-
Murphy, J.B.1
-
40
-
-
84859158384
-
Targeting the PD-1/B7-H1 (PD-L1) pathway to activate anti-tumor immunity
-
Topalian, S. L., C. G. Drake, and D. M. Pardoll. 2012. Targeting the PD-1/B7-H1 (PD-L1) pathway to activate anti-tumor immunity. Curr. Opin. Immunol. 24: 207-212.
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 207-212
-
-
Topalian, S.L.1
Drake, C.G.2
Pardoll, D.M.3
-
41
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer, J. R., S. S. Tykodi, L. Q. Chow, W. J. Hwu, S. L. Topalian, P. Hwu, C. G. Drake, L. H. Camacho, J. Kauh, K. Odunsi, et al. 2012. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. N. Engl. J. Med. 366: 2455-2465.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
-
42
-
-
84867396803
-
SiRNA-mediated silencing of PD-1 ligands enhances tumor-specific human T-cell effector functions
-
Iwamura, K., T. Kato, Y. Miyahara, H. Naota, J. Mineno, H. Ikeda, and H. Shiku. 2012. siRNA-mediated silencing of PD-1 ligands enhances tumor-specific human T-cell effector functions. Gene Ther. 19: 959-966.
-
(2012)
Gene Ther.
, vol.19
, pp. 959-966
-
-
Iwamura, K.1
Kato, T.2
Miyahara, Y.3
Naota, H.4
Mineno, J.5
Ikeda, H.6
Shiku, H.7
-
43
-
-
77953229315
-
RNA interference targeting programmed death receptor-1 improves immune functions of tumor-specific T cells
-
Borkner, L., A. Kaiser, W. van de Kasteele, R. Andreesen, A. Mackensen, J. B. Haanen, T. N. Schumacher, and C. Blank. 2010. RNA interference targeting programmed death receptor-1 improves immune functions of tumor-specific T cells. Cancer Immunol. Immunother. 59: 1173-1183.
-
(2010)
Cancer Immunol. Immunother.
, vol.59
, pp. 1173-1183
-
-
Borkner, L.1
Kaiser, A.2
Van De Kasteele, W.3
Andreesen, R.4
Mackensen, A.5
Haanen, J.B.6
Schumacher, T.N.7
Blank, C.8
-
44
-
-
84861224393
-
Tumor PD-L1 co-stimulates primary human CD8(+) cytotoxic T cells modified to express a PD1:CD28 chimeric receptor
-
Prosser, M. E., C. E. Brown, A. F. Shami, S. J. Forman, and M. C. Jensen. 2012. Tumor PD-L1 co-stimulates primary human CD8(+) cytotoxic T cells modified to express a PD1:CD28 chimeric receptor. Mol. Immunol. 51: 263-272.
-
(2012)
Mol. Immunol.
, vol.51
, pp. 263-272
-
-
Prosser, M.E.1
Brown, C.E.2
Shami, A.F.3
Forman, S.J.4
Jensen, M.C.5
-
45
-
-
84862502741
-
Positive conversion of negative signaling of CTLA4 potentiates antitumor efficacy of adoptive T-cell therapy in murine tumor models
-
Shin, J. H., H. B. Park, Y. M. Oh, D. P. Lim, J. E. Lee, H. H. Seo, S. J. Lee, H. S. Eom, I. H. Kim, S. H. Lee, and K. Choi. 2012. Positive conversion of negative signaling of CTLA4 potentiates antitumor efficacy of adoptive T-cell therapy in murine tumor models. Blood 119: 5678-5687.
-
(2012)
Blood
, vol.119
, pp. 5678-5687
-
-
Shin, J.H.1
Park, H.B.2
Oh, Y.M.3
Lim, D.P.4
Lee, J.E.5
Seo, H.H.6
Lee, S.J.7
Eom, H.S.8
Kim, I.H.9
Lee, S.H.10
Choi, K.11
-
46
-
-
65249101637
-
The promise and potential pitfalls of chimeric antigen receptors
-
Sadelain, M., R. Brentjens, and I. Rivière. 2009. The promise and potential pitfalls of chimeric antigen receptors. Curr. Opin. Immunol. 21: 215-223.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 215-223
-
-
Sadelain, M.1
Brentjens, R.2
Rivière, I.3
-
47
-
-
76349087378
-
Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication
-
Zhong, X. S., M. Matsushita, J. Plotkin, I. Riviere, and M. Sadelain. 2010. Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication. Mol. Ther. 18: 413-420.
-
(2010)
Mol. Ther.
, vol.18
, pp. 413-420
-
-
Zhong, X.S.1
Matsushita, M.2
Plotkin, J.3
Riviere, I.4
Sadelain, M.5
-
48
-
-
70350726110
-
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo
-
Milone, M. C., J. D. Fish, C. Carpenito, R. G. Carroll, G. K. Binder, D. Teachey, M. Samanta, M. Lakhal, B. Gloss, G. Danet-Desnoyers, et al. 2009. Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol. Ther. 17: 1453-1464.
-
(2009)
Mol. Ther.
, vol.17
, pp. 1453-1464
-
-
Milone, M.C.1
Fish, J.D.2
Carpenito, C.3
Carroll, R.G.4
Binder, G.K.5
Teachey, D.6
Samanta, M.7
Lakhal, M.8
Gloss, B.9
Danet-Desnoyers, G.10
-
49
-
-
84886944957
-
OX40 costimulation by a chimeric antigen receptor abrogates CD28 and IL-2 induced IL-10 secretion by redirected CD4(+) T cells
-
Hombach, A. A., J. Heiders, M. Foppe, M. Chmielewski, and H. Abken. 2012. OX40 costimulation by a chimeric antigen receptor abrogates CD28 and IL-2 induced IL-10 secretion by redirected CD4(+) T cells. OncoImmunology 1: 458-466.
-
(2012)
OncoImmunology
, vol.1
, pp. 458-466
-
-
Hombach, A.A.1
Heiders, J.2
Foppe, M.3
Chmielewski, M.4
Abken, H.5
-
50
-
-
84856071702
-
CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo
-
Song, D. G., Q. Ye, M. Poussin, G. M. Harms, M. Figini, and D. J. Powell, Jr. 2012. CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo. Blood 119: 696-706.
-
(2012)
Blood
, vol.119
, pp. 696-706
-
-
Song, D.G.1
Ye, Q.2
Poussin, M.3
Harms, G.M.4
Figini, M.5
Powell Jr., D.J.6
|