-
1
-
-
65349102966
-
Sequence, structure, function, immunity: Structural genomics of costimulation
-
Chattopadhyay K, Lazar-Molnar E, Yan Q, et al. Sequence, structure, function, immunity: structural genomics of costimulation. Immunol Rev 2009; 229: 356-86.
-
(2009)
Immunol Rev
, vol.229
, pp. 356-386
-
-
Chattopadhyay, K.1
Lazar-Molnar, E.2
Yan, Q.3
-
2
-
-
80054850038
-
The TNF receptor super family in immune regulation
-
Ware CF,. The TNF receptor super family in immune regulation. Immunol Rev 2011; 244: 5-8.
-
(2011)
Immunol Rev
, vol.244
, pp. 5-8
-
-
Ware, C.F.1
-
3
-
-
80054867338
-
T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy
-
Snell LM, Lin GH, McPherson AJ, et al. T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy. Immunol Rev 2011; 244: 197-217.
-
(2011)
Immunol Rev
, vol.244
, pp. 197-217
-
-
Snell, L.M.1
Lin, G.H.2
McPherson, A.J.3
-
4
-
-
0028009709
-
4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-mu-primed splenic B cells
-
Pollok KE, Kim YJ, Hurtado J, et al. 4-1BB T-cell antigen binds to mature B cells and macrophages, and costimulates anti-mu-primed splenic B cells. Eur J Immunol 1994; 24: 367-74.
-
(1994)
Eur J Immunol
, vol.24
, pp. 367-374
-
-
Pollok, K.E.1
Kim, Y.J.2
Hurtado, J.3
-
5
-
-
0036199305
-
Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells
-
Futagawa T, Akiba H, Kodama T, et al. Expression and function of 4-1BB and 4-1BB ligand on murine dendritic cells. Int Immunol 2002; 14: 275-86.
-
(2002)
Int Immunol
, vol.14
, pp. 275-286
-
-
Futagawa, T.1
Akiba, H.2
Kodama, T.3
-
6
-
-
0028955074
-
Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP
-
DeBenedette MA, Chu NR, Pollok KE, et al. Role of 4-1BB ligand in costimulation of T lymphocyte growth and its upregulation on M12 B lymphomas by cAMP. J Exp Med 1995; 181: 985-92.
-
(1995)
J Exp Med
, vol.181
, pp. 985-992
-
-
Debenedette, M.A.1
Chu, N.R.2
Pollok, K.E.3
-
7
-
-
0034284196
-
Constitutive expression of functional 4-1BB (CD137) ligand on carcinoma cells
-
Salih HR, Kosowski SG, Haluska VF, et al. Constitutive expression of functional 4-1BB (CD137) ligand on carcinoma cells. J Immunol 2000; 165: 2903-10.
-
(2000)
J Immunol
, vol.165
, pp. 2903-2910
-
-
Salih, H.R.1
Kosowski, S.G.2
Haluska, V.F.3
-
8
-
-
1542787537
-
Tumor expression of 4-1BB ligand sustains tumor lytic T cells
-
Zhang H, Merchant MS, Chua KS, et al. Tumor expression of 4-1BB ligand sustains tumor lytic T cells. Cancer Biol Ther 2003; 2: 579-86.
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 579-586
-
-
Zhang, H.1
Merchant, M.S.2
Chua, K.S.3
-
9
-
-
43449085812
-
Analysis of CD137 and CD137L expression in human primary tumor tissues
-
Wang Q, Zhang P, Zhang Q, et al. Analysis of CD137 and CD137L expression in human primary tumor tissues. Croat Med J 2008; 49: 192-200.
-
(2008)
Croat Med J
, vol.49
, pp. 192-200
-
-
Wang, Q.1
Zhang, P.2
Zhang, Q.3
-
10
-
-
33749128681
-
Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses
-
Lee SW, Park Y, Song A, et al. Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses. J Immunol 2006; 177: 4464-72.
-
(2006)
J Immunol
, vol.177
, pp. 4464-4472
-
-
Lee, S.W.1
Park, Y.2
Song, A.3
-
11
-
-
0030845586
-
4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses
-
Shuford WW, Klussman K, Tritchler DD, et al. 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J Exp Med 1997; 186: 47-55.
-
(1997)
J Exp Med
, vol.186
, pp. 47-55
-
-
Shuford, W.W.1
Klussman, K.2
Tritchler, D.D.3
-
12
-
-
0037094139
-
4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function
-
Wen T, Bukczynski J, Watts TH,. 4-1BB ligand-mediated costimulation of human T cells induces CD4 and CD8 T cell expansion, cytokine production, and the development of cytolytic effector function. J Immunol 2002; 168: 4897-906.
-
(2002)
J Immunol
, vol.168
, pp. 4897-4906
-
-
Wen, T.1
Bukczynski, J.2
Watts, T.H.3
-
13
-
-
79953041310
-
Costimulation through the CD137/4-1BB pathway protects human melanoma tumor-infiltrating lymphocytes from activation-induced cell death and enhances antitumor effector function
-
Hernandez-Chacon JA, Li Y, Wu RC, et al. Costimulation through the CD137/4-1BB pathway protects human melanoma tumor-infiltrating lymphocytes from activation-induced cell death and enhances antitumor effector function. J Immunother 2011; 34: 236-50.
-
(2011)
J Immunother
, vol.34
, pp. 236-250
-
-
Hernandez-Chacon, J.A.1
Li, Y.2
Wu, R.C.3
-
14
-
-
0036838689
-
4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1
-
Lee HW, Park SJ, Choi BK, et al. 4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1. J Immunol 2002; 169: 4882-8.
-
(2002)
J Immunol
, vol.169
, pp. 4882-4888
-
-
Lee, H.W.1
Park, S.J.2
Choi, B.K.3
-
15
-
-
0033137063
-
Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal
-
Takahashi C, Mittler RS, Vella AT,. Cutting edge: 4-1BB is a bona fide CD8 T cell survival signal. J Immunol 1999; 162: 5037-40.
-
(1999)
J Immunol
, vol.162
, pp. 5037-5040
-
-
Takahashi, C.1
Mittler, R.S.2
Vella, A.T.3
-
16
-
-
0141609073
-
Co-stimulatory members of the TNFR family: Keys to effective T-cell immunity?
-
Croft M,. Co-stimulatory members of the TNFR family: keys to effective T-cell immunity? Nat Rev Immunol 2003; 3: 609-20.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 609-620
-
-
Croft, M.1
-
17
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
Melero I, Shuford WW, Newby SA, et al. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med 1997; 3: 682-5.
-
(1997)
Nat Med
, vol.3
, pp. 682-685
-
-
Melero, I.1
Shuford, W.W.2
Newby, S.A.3
-
18
-
-
22944477731
-
Immunity to melanoma mediated by 4-1BB is associated with enhanced activity of tumour-infiltrating lymphocytes
-
Ju SA, Lee SC, Kwon TH, et al. Immunity to melanoma mediated by 4-1BB is associated with enhanced activity of tumour-infiltrating lymphocytes. Immunol Cell Biol 2005; 83: 344-51.
-
(2005)
Immunol Cell Biol
, vol.83
, pp. 344-351
-
-
Ju, S.A.1
Lee, S.C.2
Kwon, T.H.3
-
19
-
-
77950403194
-
CD137 agonist antibody prevents cancer recurrence: Contribution of CD137 on both hematopoietic and nonhematopoietic cells
-
Narazaki H, Zhu Y, Luo L, et al. CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells. Blood 2010; 115: 1941-8.
-
(2010)
Blood
, vol.115
, pp. 1941-1948
-
-
Narazaki, H.1
Zhu, Y.2
Luo, L.3
-
20
-
-
84858758766
-
Adoptive immunotherapy for cancer: Harnessing the T cell response
-
Restifo NP, Dudley ME, Rosenberg SA,. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat Rev Immunol 2012; 12: 269-81.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 269-281
-
-
Restifo, N.P.1
Dudley, M.E.2
Rosenberg, S.A.3
-
21
-
-
79960299888
-
Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy
-
Rosenberg SA, Yang JC, Sherry RM, et al. Durable complete responses in heavily pretreated patients with metastatic melanoma using T-cell transfer immunotherapy. Clin Cancer Res 2011; 17: 4550-7.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 4550-4557
-
-
Rosenberg, S.A.1
Yang, J.C.2
Sherry, R.M.3
-
22
-
-
10344261422
-
Cutting edge: Persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy
-
Robbins PF, Dudley ME, Wunderlich J, et al. Cutting edge: persistence of transferred lymphocyte clonotypes correlates with cancer regression in patients receiving cell transfer therapy. J Immunol 2004; 173: 7125-30.
-
(2004)
J Immunol
, vol.173
, pp. 7125-7130
-
-
Robbins, P.F.1
Dudley, M.E.2
Wunderlich, J.3
-
24
-
-
0141449956
-
Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production
-
Topp MS, Riddell SR, Akatsuka Y, et al. Restoration of CD28 expression in CD28- CD8+ memory effector T cells reconstitutes antigen-induced IL-2 production. J Exp Med 2003; 198: 947-55.
-
(2003)
J Exp Med
, vol.198
, pp. 947-955
-
-
Topp, M.S.1
Riddell, S.R.2
Akatsuka, Y.3
-
25
-
-
78049468066
-
T cells expressing constitutively active Akt resist multiple tumor-associated inhibitory mechanisms
-
Sun J, Dotti G, Huye LE, et al. T cells expressing constitutively active Akt resist multiple tumor-associated inhibitory mechanisms. Mol Ther 2010; 18: 2006-17.
-
(2010)
Mol Ther
, vol.18
, pp. 2006-2017
-
-
Sun, J.1
Dotti, G.2
Huye, L.E.3
-
26
-
-
27144435476
-
Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR
-
Cohen CJ, Zheng Z, Bray R, et al. Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR. J Immunol 2005; 175: 5799-808.
-
(2005)
J Immunol
, vol.175
, pp. 5799-5808
-
-
Cohen, C.J.1
Zheng, Z.2
Bray, R.3
-
27
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan RA, Dudley ME, Wunderlich JR, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006; 314: 126-9.
-
(2006)
Science
, vol.314
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
-
28
-
-
84862077998
-
Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity
-
Haga-Friedman A, Horovitz-Fried M, Cohen CJ,. Incorporation of transmembrane hydrophobic mutations in the TCR enhance its surface expression and T cell functional avidity. J Immunol 2012; 188: 5538-46.
-
(2012)
J Immunol
, vol.188
, pp. 5538-5546
-
-
Haga-Friedman, A.1
Horovitz-Fried, M.2
Cohen, C.J.3
-
29
-
-
77953458193
-
Selected murine residues endow human TCR with enhanced tumor recognition
-
Bialer G, Horovitz-Fried M, Ya'acobi S, et al. Selected murine residues endow human TCR with enhanced tumor recognition. J Immunol 2010; 184: 6232-41.
-
(2010)
J Immunol
, vol.184
, pp. 6232-6241
-
-
Bialer, G.1
Horovitz-Fried, M.2
Ya'Acobi, S.3
-
30
-
-
0024390061
-
Tumor-specific cytolysis by lymphocytes infiltrating human melanomas
-
Topalian SL, Solomon D, Rosenberg SA,. Tumor-specific cytolysis by lymphocytes infiltrating human melanomas. J Immunol 1989; 142: 3714-25.
-
(1989)
J Immunol
, vol.142
, pp. 3714-3725
-
-
Topalian, S.L.1
Solomon, D.2
Rosenberg, S.A.3
-
31
-
-
0023243241
-
Phenotypic heterogeneity of melanoma. Relation to the differentiation program of melanoma cells
-
Houghton AN, Real FX, Davis LJ, et al. Phenotypic heterogeneity of melanoma. Relation to the differentiation program of melanoma cells. J Exp Med 1987; 165: 812-29.
-
(1987)
J Exp Med
, vol.165
, pp. 812-829
-
-
Houghton, A.N.1
Real, F.X.2
Davis, L.J.3
-
32
-
-
84862739640
-
Immunotherapy of cancer with 4-1BB
-
Vinay DS, Kwon BS,. Immunotherapy of cancer with 4-1BB. Mol Cancer Ther 2012; 11: 1062-70.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1062-1070
-
-
Vinay, D.S.1
Kwon, B.S.2
-
33
-
-
27644457376
-
TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance
-
Thomas DA, Massague J,. TGF-beta directly targets cytotoxic T cell functions during tumor evasion of immune surveillance. Cancer Cell 2005; 8: 369-80.
-
(2005)
Cancer Cell
, vol.8
, pp. 369-380
-
-
Thomas, D.A.1
Massague, J.2
-
34
-
-
0036171757
-
Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB
-
Maus MV, Thomas AK, Leonard DG, et al. Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB. Nat Biotechnol 2002; 20: 143-8.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 143-148
-
-
Maus, M.V.1
Thomas, A.K.2
Leonard, D.G.3
-
35
-
-
36849021712
-
T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection
-
Stephan MT, Ponomarev V, Brentjens RJ, et al. T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection. Nat Med 2007; 13: 1440-9.
-
(2007)
Nat Med
, vol.13
, pp. 1440-1449
-
-
Stephan, M.T.1
Ponomarev, V.2
Brentjens, R.J.3
-
36
-
-
80055018750
-
Augmented lymphocyte expansion from solid tumors with engineered cells for costimulatory enhancement
-
Friedman KM, Devillier LE, Feldman SA, et al. Augmented lymphocyte expansion from solid tumors with engineered cells for costimulatory enhancement. J Immunother 2011; 34: 651-61.
-
(2011)
J Immunother
, vol.34
, pp. 651-661
-
-
Friedman, K.M.1
Devillier, L.E.2
Feldman, S.A.3
-
37
-
-
33644500140
-
IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival
-
Pulle G, Vidric M, Watts TH,. IL-15-dependent induction of 4-1BB promotes antigen-independent CD8 memory T cell survival. J Immunol 2006; 176: 2739-48.
-
(2006)
J Immunol
, vol.176
, pp. 2739-2748
-
-
Pulle, G.1
Vidric, M.2
Watts, T.H.3
-
38
-
-
70350726110
-
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo
-
Milone MC, Fish JD, Carpenito C, et al. Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo. Mol Ther 2009; 17: 1453-64.
-
(2009)
Mol Ther
, vol.17
, pp. 1453-1464
-
-
Milone, M.C.1
Fish, J.D.2
Carpenito, C.3
-
39
-
-
0036175995
-
4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity
-
Cooper D, Bansal-Pakala P, Croft M,. 4-1BB (CD137) controls the clonal expansion and survival of CD8 T cells in vivo but does not contribute to the development of cytotoxicity. Eur J Immunol 2002; 32: 521-9.
-
(2002)
Eur J Immunol
, vol.32
, pp. 521-529
-
-
Cooper, D.1
Bansal-Pakala, P.2
Croft, M.3
-
40
-
-
0000970685
-
Transplantability of tissues to the embryo of foreign species: Its bearing on questions of tissue specificity and tumor immunity
-
Murphy JB,. Transplantability of tissues to the embryo of foreign species: its bearing on questions of tissue specificity and tumor immunity. J Exp Med 1913; 17: 482-93.
-
(1913)
J Exp Med
, vol.17
, pp. 482-493
-
-
Murphy, J.B.1
-
41
-
-
33947696816
-
Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice
-
Niu L, Strahotin S, Hewes B, et al. Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice. J Immunol 2007; 178: 4194-213.
-
(2007)
J Immunol
, vol.178
, pp. 4194-4213
-
-
Niu, L.1
Strahotin, S.2
Hewes, B.3
-
42
-
-
0033571176
-
Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy
-
Mittler RS, Bailey TS, Klussman K, et al. Anti-4-1BB monoclonal antibodies abrogate T cell-dependent humoral immune responses in vivo through the induction of helper T cell anergy. J Exp Med 1999; 190: 1535-40.
-
(1999)
J Exp Med
, vol.190
, pp. 1535-1540
-
-
Mittler, R.S.1
Bailey, T.S.2
Klussman, K.3
-
43
-
-
77951042495
-
CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells
-
Baessler T, Charton JE, Schmiedel BJ, et al. CD137 ligand mediates opposite effects in human and mouse NK cells and impairs NK-cell reactivity against human acute myeloid leukemia cells. Blood 2010; 115: 3058-69.
-
(2010)
Blood
, vol.115
, pp. 3058-3069
-
-
Baessler, T.1
Charton, J.E.2
Schmiedel, B.J.3
-
44
-
-
78449237499
-
Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies
-
Ascierto PA, Simeone E, Sznol M, et al. Clinical experiences with anti-CD137 and anti-PD1 therapeutic antibodies. Semin Oncol 2010; 37: 508-16.
-
(2010)
Semin Oncol
, vol.37
, pp. 508-516
-
-
Ascierto, P.A.1
Simeone, E.2
Sznol, M.3
-
45
-
-
34548590892
-
Agonistic anti-4-1BB antibody promotes the expansion of natural regulatory T cells while maintaining Foxp3 expression
-
Zhang P, Gao F, Wang Q, et al. Agonistic anti-4-1BB antibody promotes the expansion of natural regulatory T cells while maintaining Foxp3 expression. Scand J Immunol 2007; 66: 435-40.
-
(2007)
Scand J Immunol
, vol.66
, pp. 435-440
-
-
Zhang, P.1
Gao, F.2
Wang, Q.3
-
46
-
-
79960657821
-
Autoimmunity associated with immunotherapy of cancer
-
Amos SM, Duong CP, Westwood JA, et al. Autoimmunity associated with immunotherapy of cancer. Blood 2011; 118: 499-509.
-
(2011)
Blood
, vol.118
, pp. 499-509
-
-
Amos, S.M.1
Duong, C.P.2
Westwood, J.A.3
-
47
-
-
0022485359
-
Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: Paradigm for a prospective cancer control strategy
-
Moolten FL,. Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy. Cancer Res 1986; 46: 5276-81.
-
(1986)
Cancer Res
, vol.46
, pp. 5276-5281
-
-
Moolten, F.L.1
-
48
-
-
76749120309
-
A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity
-
Zhao Y, Wang QJ, Yang S, et al. A herceptin-based chimeric antigen receptor with modified signaling domains leads to enhanced survival of transduced T lymphocytes and antitumor activity. J Immunol 2009; 183: 5563-74.
-
(2009)
J Immunol
, vol.183
, pp. 5563-5574
-
-
Zhao, Y.1
Wang, Q.J.2
Yang, S.3
-
49
-
-
76349087378
-
Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication
-
Zhong XS, Matsushita M, Plotkin J, et al. Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication. Mol Ther 2010; 18: 413-20.
-
(2010)
Mol Ther
, vol.18
, pp. 413-420
-
-
Zhong, X.S.1
Matsushita, M.2
Plotkin, J.3
-
50
-
-
56749097952
-
Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis
-
Deryugina EI, Quigley JP,. Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis. Histochem Cell Biol 2008; 130: 1119-30.
-
(2008)
Histochem Cell Biol
, vol.130
, pp. 1119-1130
-
-
Deryugina, E.I.1
Quigley, J.P.2
|