(S)-1-(4-Dimethylaminophenylcarbonyl)-3-aminopyrrolidine: A derivatization reagent for enantiomeric separation and sensitive detection of chiral carboxylic acids by LC/ESI-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 940, Issue , 2013, Pages 7-14

  Ogawa, Shoujiro ^a   Tadokoro, Hiroaki ^a   Sato, Maho ^a   Hanawa, Takehisa ^a   Higashi, Tatsuya ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Chiral carboxylic acid; Derivatization reagent; Enantiomeric separation; Increasing sensitivity; LC ESI MS MS

Indexed keywords

CHIRAL CARBOXYLIC ACIDS; DERIVATIZATION REAGENT; ENANTIOMERIC SEPARATION; INCREASING SENSITIVITIES; LC/ESI-MS/MS;

CHLORINE COMPOUNDS; ENANTIOMERS; IONIZATION OF LIQUIDS; MASS SPECTROMETRY; SEPARATION;

CARBOXYLIC ACIDS;

1 (4 DIMETHYLAMINOPHENYLCARBONYL) 3 AMINOPYRROLIDINE; CARBOXYLIC ACID; ETODOLAC; IBUPROFEN; KETOPROFEN; NAPROXEN; PYRROLIDINE DERIVATIVE; REAGENT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIOLOGICAL MONITORING; CHEMICAL ANALYSIS; CHIRALITY; DERIVATIZATION; DIASTEREOISOMER; ELECTROSPRAY MASS SPECTROMETRY; ENANTIOMER; EPIMERIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; ROOM TEMPERATURE; SALIVA; TANDEM MASS SPECTROMETRY;

CHIRAL CARBOXYLIC ACID; DERIVATIZATION REAGENT; ENANTIOMERIC SEPARATION; INCREASING SENSITIVITY; LC/ESI-MS/MS;

ARABIDOPSIS PROTEINS; CARBOXYLIC ACIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; LIMIT OF DETECTION; MORPHOLINES; PYRROLIDINES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84885438609     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.09.025     Document Type: Article

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