Improved sensitivity mass spectrometric detection of eicosanoids by charge reversal derivatization

Analytical Chemistry

Volumn 82, Issue 16, 2010, Pages 6790-6796

  Bollinger, James G ^a   Thompson, Wallace ^a   Lai, Ying ^a   Oslund, Rob C ^a   Hallstrand, Teal S ^a   Sadilek, Martin ^a   Turecek, Frantisek ^a   Gelb, Michael H ^a,b  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE LINKAGES; ANALYTES; ARACHIDONIC ACIDS; BIOLOGICAL SAMPLES; CHARGE REVERSAL; COLLISION-INDUCED DISSOCIATION; DERIVATIZATION METHOD; DERIVATIZATION REAGENT; DERIVATIZATIONS; EICOSANOIDS; ELECTROSPRAY IONIZATION TANDEM MASS SPECTROMETRY; ENHANCED SENSITIVITY; LC-ESI-MS/MS; LIMITS OF QUANTIFICATION; MASS SPECTROMETRIC DETECTION; POLYUNSATURATED FATTY ACIDS; PYRIDINIUM; QUANTITATIVE YIELDS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

AMIDES; DYES; FATTY ACIDS; IONIZATION; ISOMERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MASS SPECTROMETRY; ORGANIC ACIDS; PARTICLE DETECTORS;

ELECTROSPRAY IONIZATION;

HYDROXYICOSATETRAENOIC ACID; ICOSANOID; LEUKOTRIENE B4; N (4 AMINOMETHYLPHENYL)PYRIDINIUM; N-(4-AMINOMETHYLPHENYL)PYRIDINIUM; PROSTAGLANDIN; PYRIDINIUM DERIVATIVE; THROMBOXANE B2;

ANIMAL; ARTICLE; CELL CULTURE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; EPITHELIUM CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; METHODOLOGY; MOUSE; RAT;

ANIMALS; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EICOSANOIDS; EPITHELIAL CELLS; HUMANS; HYDROXYEICOSATETRAENOIC ACIDS; LEUKOTRIENE B4; MICE; PROSTAGLANDINS; PYRIDINIUM COMPOUNDS; RATS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; THROMBOXANE B2;

EID: 77955605929     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac100720p     Document Type: Article

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