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Volumn 46, Issue 7, 2013, Pages 429-438

B cell homeostasis is disturbed by immunosuppressive therapies in patients with ANCA-associated vasculitides

Author keywords

Antineutrophil cytoplasmic antibody (ANCA); B lymphocytes; Cyclophosphamide; Granulomatosis with polyangiitis (GPA, Wegener's); Rituximab

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; GLUCOCORTICOID; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; LEFLUNOMIDE; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; RITUXIMAB;

EID: 84885436190     PISSN: 08916934     EISSN: 1607842X     Source Type: Journal    
DOI: 10.3109/08916934.2013.798652     Document Type: Article
Times cited : (18)

References (48)
  • 1
    • 0942290440 scopus 로고    scopus 로고
    • Peripheral development of B cells in mouse and man
    • DOI 10.1111/j.0105-2896.2004.0109.x
    • Carsetti, R., M. M. Rosado, and H. Wardmann. 2004. Peripheral development of B cells in mouse and man. Immunol Rev. 197: 179-191. (Pubitemid 38142176)
    • (2004) Immunological Reviews , vol.197 , pp. 179-191
    • Carsetti, R.1    Rosado, M.M.2    Wardemann, H.3
  • 2
    • 33744490073 scopus 로고    scopus 로고
    • Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway
    • DOI 10.1182/blood-2005-05-1875
    • Csernok, E., M. Ai, W. L. Gross, D. Wicklein, A. Petersen, B. Lindner, P. Lamprecht, et al. 2006. Wegener autoantigen induces maturation of dendritic cells and licenses them for Th1 priming via the protease-activated receptor-2 pathway. Blood. 107: 4440-4448. (Pubitemid 43801371)
    • (2006) Blood , vol.107 , Issue.11 , pp. 4440-4448
    • Csernok, E.1    Ai, M.2    Gross, W.L.3    Wicklein, D.4    Petersen, A.5    Lindner, B.6    Lamprecht, P.7    Holle, J.U.8    Hellmich, B.9
  • 4
    • 71049189995 scopus 로고    scopus 로고
    • Mechanisms and markers of vascular damage in ANCA-associated vasculitis
    • Haubitz, M., A. Dhaygude, and A. Woywodt. 2009. Mechanisms and markers of vascular damage in ANCA-associated vasculitis. Autoimmunity. 42: 605-614.
    • (2009) Autoimmunity. , vol.42 , pp. 605-614
    • Haubitz, M.1    Dhaygude, A.2    Woywodt, A.3
  • 5
    • 17144412184 scopus 로고    scopus 로고
    • Antineutrophil cytoplasmic antibodies (ANCA)
    • DOI 10.1080/08916930400022673
    • Radice, A., and R. A. Sinico. 2005. Antineutrophil cytoplasmic antibodies (ANCA). Autoimmunity. 38: 93-103. (Pubitemid 40515009)
    • (2005) Autoimmunity , vol.38 , Issue.1 , pp. 93-103
    • Radice, A.1    Sinico, R.A.2
  • 7
    • 84860389678 scopus 로고    scopus 로고
    • ANCA-stimulated neutrophils release BLyS and promote B cell survival: A clinically relevant cellular process
    • Holden, N. J., J. M. Williams, M. D. Morgan, A. Challa, J. Gordon, R. J. Pepper, A. D. Salama, et al. 2011. ANCA-stimulated neutrophils release BLyS and promote B cell survival: a clinically relevant cellular process. Ann Rheum Dis. 70: 2229-2233.
    • (2011) Ann Rheum Dis. , vol.70 , pp. 2229-2233
    • Holden, N.J.1    Williams, J.M.2    Morgan, M.D.3    Challa, A.4    Gordon, J.5    Pepper, R.J.6    Salama, A.D.7
  • 8
    • 84855384962 scopus 로고    scopus 로고
    • B cell strategy to maintain remission in ANCA-associated vasculitides?
    • Adler, S., and P. M. Villiger. 2012. B cell strategy to maintain remission in ANCA-associated vasculitides? J Rheumatol. 39: 4-5.
    • (2012) J Rheumatol. , vol.39 , pp. 4-5
    • Adler, S.1    Villiger, P.M.2
  • 9
    • 79953319774 scopus 로고    scopus 로고
    • Increased expression of B cell activation factor supports the abnormal expansion of transitional B cells in systemic lupus erythematosus
    • Landolt-Marticorena, C., R. Wither, H. Reich, A. Herzenberg, J. Scholey, D. D. Gladman, M. B. Urowitz, et al. 2011. Increased expression of B cell activation factor supports the abnormal expansion of transitional B cells in systemic lupus erythematosus. J Rheumatol. 38: 642-651.
    • (2011) J Rheumatol. , vol.38 , pp. 642-651
    • Landolt-Marticorena, C.1    Wither, R.2    Reich, H.3    Herzenberg, A.4    Scholey, J.5    Gladman, D.D.6    Urowitz, M.B.7
  • 11
    • 70449513451 scopus 로고    scopus 로고
    • T-lymphocytes and disease mechanisms in Wegener's granulomatosis
    • Hua, F., B. Wilde, S. Dolff, and O. Witzke. 2009. T-lymphocytes and disease mechanisms in Wegener's granulomatosis. Kidney Blood Press Res. 32: 389-398.
    • (2009) Kidney Blood Press Res. , vol.32 , pp. 389-398
    • Hua, F.1    Wilde, B.2    Dolff, S.3    Witzke, O.4
  • 13
    • 55449110759 scopus 로고    scopus 로고
    • Single cell analysis of B lymphocytes from Wegener's granulomatosis: B cell receptors display affinity maturation within the granulomatous lesions
    • Voswinkel, J., G. Assmann, G. Held, S. Pitann, W. L. Gross, K. Holl-Ulrich, K. Herlyn, and A. Mueller. 2008. Single cell analysis of B lymphocytes from Wegener's granulomatosis: B cell receptors display affinity maturation within the granulomatous lesions. Clin Exp Immunol. 154: 339-345.
    • (2008) Clin Exp Immunol. , vol.154 , pp. 339-345
    • Voswinkel, J.1    Assmann, G.2    Held, G.3    Pitann, S.4    Gross, W.L.5    Holl-Ulrich, K.6    Herlyn, K.7    Mueller, A.8
  • 14
    • 79151486085 scopus 로고    scopus 로고
    • Wegener's granuloma harbors B lymphocytes with specificities against a proinflammatory transmembrane protein and a tetraspanin
    • Thurner, L., A. Müller, M. Cérutti, T. Martin, J.-L. Pasquali, W. L. Gross, K.-D. Preuss, et al. 2011. Wegener's granuloma harbors B lymphocytes with specificities against a proinflammatory transmembrane protein and a tetraspanin. J Autoimmun. 36: 87-90.
    • (2011) J Autoimmun. , vol.36 , pp. 87-90
    • Thurner, L.1    Müller, A.2    Cérutti, M.3    Martin, T.4    Pasquali, J.-L.5    Gross, W.L.6    Preuss, K.-D.7
  • 15
    • 77957865413 scopus 로고    scopus 로고
    • B cell abnormalities in Wegener's granulomatosis and microscopic polyangiitis: Role of CD25\+-expressing B cells
    • Eriksson, P., C. Sandell, K. Backteman, and J. Ernerudh. 2010. B cell abnormalities in Wegener's granulomatosis and microscopic polyangiitis: role of CD25\+-expressing B cells. J Rheumatol. 37: 2086-2095.
    • (2010) J Rheumatol. , vol.37 , pp. 2086-2095
    • Eriksson, P.1    Sandell, C.2    Backteman, K.3    Ernerudh, J.4
  • 16
    • 82955235599 scopus 로고    scopus 로고
    • Takayasu arteritis is characterised by disturbances of B cell homeostasis and responds to B cell depletion therapy with rituximab
    • Hoyer, B. F., I. M. Mumtaz, K. Loddenkemper, A. Bruns, C. Sengler, K.-G. Hermann, S. Maza, et al. 2012. Takayasu arteritis is characterised by disturbances of B cell homeostasis and responds to B cell depletion therapy with rituximab. Ann Rheum Dis. 71: 75-79.
    • (2012) Ann Rheum Dis. , vol.71 , pp. 75-79
    • Hoyer, B.F.1    Mumtaz, I.M.2    Loddenkemper, K.3    Bruns, A.4    Sengler, C.5    Hermann, K.-G.6    Maza, S.7
  • 17
    • 19344376101 scopus 로고    scopus 로고
    • Identification and characterization of circulating human transitional B cells
    • DOI 10.1182/blood-2004-11-4284
    • Sims, G. P., R. Ettinger, Y. Shirota, C. H. Yarboro, G. G. Illei, and P. E. Lipsky. 2005. Identification and characterization of circulating human transitional B cells. Blood. 105: 4390-4398. (Pubitemid 40720786)
    • (2005) Blood , vol.105 , Issue.11 , pp. 4390-4398
    • Sims, G.P.1    Ettinger, R.2    Shirota, Y.3    Yarboro, C.H.4    Illei, G.G.5    Lipsky, P.E.6
  • 18
    • 33746942234 scopus 로고    scopus 로고
    • Regeneration of B cell subsets after transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis
    • DOI 10.1002/art.22019
    • Roll, P., A. Palanichamy, C. Kneitz, T. Dorner, and H.-P. Tony. 2006. Regeneration of B cell subsets after transient B cell depletion using anti-CD20 antibodies in rheumatoid arthritis. Arthritis Rheum. 54: 2377-2386. (Pubitemid 44204997)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.8 , pp. 2377-2386
    • Roll, P.1    Palanichamy, A.2    Kneitz, C.3    Dorner, T.4    Tony, H.-P.5
  • 19
    • 84861318148 scopus 로고    scopus 로고
    • Impact of rituximab on Immunoglobulin concentrations and B cell numbers after cyclophosphamide treatment in patients with ANCA-associated vasculitides
    • Venhoff, N., N. M. Effelsberg, U. Salzer, K. Warnatz, H.-H. Peter, D. Lebrecht, M. Schlesier, et al. 2012. impact of rituximab on Immunoglobulin concentrations and B cell numbers after cyclophosphamide treatment in patients with ANCA-associated vasculitides. PLoS One. 7: e37626.
    • (2012) PLoS One. , vol.7
    • Venhoff, N.1    Effelsberg, N.M.2    Salzer, U.3    Warnatz, K.4    Peter, H.-H.5    Lebrecht, D.6    Schlesier, M.7
  • 20
    • 78149329145 scopus 로고    scopus 로고
    • CD21low B cells in common variable immunodeficiency do not show defects in receptor editing, but resemble tissue-like memory B cells
    • Rakhmanov, M., S. Gutenberger, B. Keller, M. Schlesier, H.-H. Peter, and K. Warnatz. 2010. CD21low B cells in common variable immunodeficiency do not show defects in receptor editing, but resemble tissue-like memory B cells. Blood. 116: 3682-3683.
    • (2010) Blood. , vol.116 , pp. 3682-3683
    • Rakhmanov, M.1    Gutenberger, S.2    Keller, B.3    Schlesier, M.4    Peter, H.-H.5    Warnatz, K.6
  • 21
    • 84872425371 scopus 로고    scopus 로고
    • Clonal expansion and functional exhaustion of monoclonal marginal zone B cells in mixed cryoglobulinemia: The yin and yang of HCV-driven lymphoproliferation and autoimmunity
    • Visentini, M., V. Conti, C. Cristofoletti, C. Lazzeri, R. Marrapodi, G. Russo, M. Casato, and M. Fiorilli. 2012. Clonal expansion and functional exhaustion of monoclonal marginal zone B cells in mixed cryoglobulinemia: the yin and yang of HCV-driven lymphoproliferation and autoimmunity. Autoimmun Rev. 12: 430-435.
    • (2012) Autoimmun Rev. , vol.12 , pp. 430-435
    • Visentini, M.1    Conti, V.2    Cristofoletti, C.3    Lazzeri, C.4    Marrapodi, R.5    Russo, G.6    Casato, M.7    Fiorilli, M.8
  • 22
    • 38049105639 scopus 로고    scopus 로고
    • The EUROclass trial: Defining subgroups in common variable immunodeficiency
    • Wehr, C., T. Kivioja, C. Schmitt, B. Ferry, T. Witte, E. Eren, M. Vlkova, et al. 2008. The EUROclass trial: defining subgroups in common variable immunodeficiency. Blood. 111: 77-85.
    • (2008) Blood. , vol.111 , pp. 77-85
    • Wehr, C.1    Kivioja, T.2    Schmitt, C.3    Ferry, B.4    Witte, T.5    Eren, E.6    Vlkova, M.7
  • 23
    • 51749093932 scopus 로고    scopus 로고
    • Flowcytometric phenotyping of common variable immunodeficiency
    • Warnatz, K., and M. Schlesier. 2008. Flowcytometric phenotyping of common variable immunodeficiency. Cytometry B Clin Cytom. 74: 261-271.
    • (2008) Cytometry B Clin Cytom. , vol.74 , pp. 261-271
    • Warnatz, K.1    Schlesier, M.2
  • 25
    • 2942518502 scopus 로고    scopus 로고
    • Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches
    • DOI 10.1016/j.immuni.2004.05.010, PII S107476130400144X
    • Thien, M., T. G. Phan, S. Gardam, M. Amesbury, A. Basten, F. Mackay, and R. Brink. 2004. Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches. Immunity. 20: 785-798. (Pubitemid 38757447)
    • (2004) Immunity , vol.20 , Issue.6 , pp. 785-798
    • Thien, M.1    Phan, T.G.2    Gardam, S.3    Amesbury, M.4    Basten, A.5    MacKay, F.6    Brink, R.7
  • 26
    • 78049494232 scopus 로고    scopus 로고
    • BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling
    • Rowland, S. L., K. F. Leahy, R. Halverson, R. M. Torres, and R. Pelanda. 2010. BAFF receptor signaling aids the differentiation of immature B cells into transitional B cells following tonic BCR signaling. J Immunol. 185: 4570-4581.
    • (2010) J Immunol. , vol.185 , pp. 4570-4581
    • Rowland, S.L.1    Leahy, K.F.2    Halverson, R.3    Torres, R.M.4    Pelanda, R.5
  • 27
    • 4644293557 scopus 로고    scopus 로고
    • low B cell population in the peripheral blood of patients with SLE
    • DOI 10.1016/j.clim.2004.05.010, PII S1521661604001810
    • Wehr, C., H. Eibel, M. Masilamani, H. Illges, M. Schlesier, H.-H. Peter, and K. Warnatz. 2004. A new CD21low B cell population in the peripheral blood of patients with SLE. Clin Immunol. 113: 161-171. (Pubitemid 39296849)
    • (2004) Clinical Immunology , vol.113 , Issue.2 , pp. 161-171
    • Wehr, C.1    Eibel, H.2    Masilamani, M.3    Illges, H.4    Schlesier, M.5    Peter, H.-H.6    Warnatz, K.7
  • 28
    • 0035478494 scopus 로고    scopus 로고
    • Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjögren's syndrome
    • Bohnhorst, J., M. B. Bjørgan, J. E. Thoen, J. B. Natvig, and K. M. Thompson. 2001. Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjögren's syndrome. J Immunol. 167: 3610-3618. (Pubitemid 32916053)
    • (2001) Journal of Immunology , vol.167 , Issue.7 , pp. 3610-3618
    • Bohnhorst, J.O.1    Bjorgan, M.B.2    Thoen, J.E.3    Natvig, J.B.4    Thompson, K.M.5
  • 29
    • 34848912304 scopus 로고    scopus 로고
    • Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy
    • DOI 10.1002/art.22810
    • Anolik, J. H., J. Barnard, T. Owen, B. Zheng, S. Kemshetti, R. J. Looney, and I. Sanz. 2007. Delayed memory B cell recovery in peripheral blood and lymphoid tissue in systemic lupus erythematosus after B cell depletion therapy. Arthritis Rheum. 56: 3044-3056. (Pubitemid 47502752)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.9 , pp. 3044-3056
    • Anolik, J.H.1    Barnard, J.2    Owen, T.3    Zheng, B.4    Kemshetti, S.5    Looney, R.J.6    Sanz, I.7
  • 35
    • 70249126884 scopus 로고    scopus 로고
    • Immunosuppressive drugs have different effect on B lymphocyte subsets and IgM antibody production in immunized BALB/c mice
    • Salinas-Carmona, M. C., L. I. Perez, K. Galan, and A. V. Vazquez. 2009. Immunosuppressive drugs have different effect on B lymphocyte subsets and IgM antibody production in immunized BALB/c mice. Autoimmunity. 42: 537-544.
    • (2009) Autoimmunity. , vol.42 , pp. 537-544
    • Salinas-Carmona, M.C.1    Perez, L.I.2    Galan, K.3    Vazquez, A.V.4
  • 36
    • 0034949949 scopus 로고    scopus 로고
    • Slow recovery of follicular B cells and marginal zone B cells after chemotherapy: Implications for humoral immunity
    • DOI 10.1046/j.1365-2249.2001.01530.x
    • Zandvoort, A., M. E. Lodewijk, P. A. Klok, P. M. Dammers, F. G. Kroese, and W. Timens. 2001. Slow recovery of follicular B cells and marginal zone B cells after chemotherapy: implications for humoral immunity. Clin Exp Immunol. 124: 172-179. (Pubitemid 32587600)
    • (2001) Clinical and Experimental Immunology , vol.124 , Issue.2 , pp. 172-179
    • Zandvoort, A.1    Lodewijk, M.E.2    Klok, P.A.3    Dammers, P.M.4    Kroese, F.G.M.5    Timens, W.6
  • 38
    • 0034121629 scopus 로고    scopus 로고
    • Splenic infarction in Wegener's granulomatosis
    • Rentsch, J., and G. McColl. 2000. Splenic infarction in Wegener's granulomatosis. J Rheumatol. 27: 1554-1555. (Pubitemid 30354064)
    • (2000) Journal of Rheumatology , vol.27 , Issue.6 , pp. 1554-1555
    • Rentsch, J.1    Mccoll, G.2
  • 39
    • 0029957578 scopus 로고    scopus 로고
    • Splenic involvement inWegener's granulomatosis
    • Gal, A. A., and J. J. Masor. 1996. Splenic involvement inWegener's granulomatosis. Arch Pathol Lab Med. 120: 974-977.
    • (1996) Arch Pathol Lab Med. , vol.120 , pp. 974-977
    • Gal, A.A.1    Masor, J.J.2
  • 40
  • 42
    • 84855962862 scopus 로고    scopus 로고
    • B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen
    • Puga, I., M. Cols, C. M. Barra, B. He, L. Cassis, M. Gentile, L. Comerma, et al. 2012. B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen. Nature. 13: 170-180.
    • (2012) Nature. , vol.13 , pp. 170-180
    • Puga, I.1    Cols, M.2    Barra, C.M.3    He, B.4    Cassis, L.5    Gentile, M.6    Comerma, L.7
  • 43
    • 73449114618 scopus 로고    scopus 로고
    • HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus
    • Jacobi, A. M., H. Mei, B. F. Hoyer, I. M. Mumtaz, K. Thiele, A. Radbruch, G. R. Burmester, et al. 2010. HLA-DRhigh/CD27high plasmablasts indicate active disease in patients with systemic lupus erythematosus. Ann Rheum Dis. 69: 305-308.
    • (2010) Ann Rheum Dis. , vol.69 , pp. 305-308
    • Jacobi, A.M.1    Mei, H.2    Hoyer, B.F.3    Mumtaz, I.M.4    Thiele, K.5    Radbruch, A.6    Burmester, G.R.7
  • 45
    • 0036493366 scopus 로고    scopus 로고
    • -) in subgroups of patients with common variable immunodeficiency: A new approach to classify a heterogeneous disease
    • DOI 10.1182/blood.V99.5.1544
    • Warnatz, K., A. Denz, R. Dräger, M. Braun, C. Groth, G. Wolff-Vorbeck, H. Eibel, et al. 2002. Severe deficiency of switched memory B cells (CD27(\+)IgM IgD in subgroups of patients with common variable immunodeficiency: a new approach to classify a heterogeneous disease. Blood 99: 1544-1551. (Pubitemid 34533024)
    • (2002) Blood , vol.99 , Issue.5 , pp. 1544-1551
    • Warnatz, K.1    Denz, A.2    Drager, R.3    Braun, M.4    Groth, C.5    Wolff-Vorbeck, G.6    Eibel, H.7    Schlesier, M.8    Peter, H.H.9
  • 46
    • 46049112339 scopus 로고    scopus 로고
    • Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
    • Moir, S., J. Ho, A. Malaspina, W. Wang, A. C. DiPoto, M. A. O'Shea, G. Roby, et al. 2008. Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exper Med. 205: 1797-1805.
    • (2008) J Exper Med. , vol.205 , pp. 1797-1805
    • Moir, S.1    Ho, J.2    Malaspina, A.3    Wang, W.4    Dipoto, A.C.5    O'Shea, M.A.6    Roby, G.7
  • 47
    • 84862128472 scopus 로고    scopus 로고
    • Clonal B cells of HCV-associated mixed cryoglobulinemia patients contain exhausted marginal zone-like and CD21 low cells overexpressing Stra13
    • Visentini, M., M. Cagliuso, V. Conti, M. Carbonari, M. Cibati, G. Siciliano, C. Cristofoletti, et al. 2012. Clonal B cells of HCV-associated mixed cryoglobulinemia patients contain exhausted marginal zone-like and CD21 low cells overexpressing Stra13. Eur J Immunol. 42: 1468-1476.
    • (2012) Eur J Immunol. , vol.42 , pp. 1468-1476
    • Visentini, M.1    Cagliuso, M.2    Conti, V.3    Carbonari, M.4    Cibati, M.5    Siciliano, G.6    Cristofoletti, C.7
  • 48
    • 77954684486 scopus 로고    scopus 로고
    • Complement receptor 2/CD21-human naive B cells contain mostly autoreactive unresponsive clones
    • Isnardi, I., Y.-S. Ng, L. Menard, G. Meyers, D. Saadoun, I. Srdanovic, J. Samuels, et al. 2010. Complement receptor 2/CD21-human naive B cells contain mostly autoreactive unresponsive clones. Blood 115: 5026-5036.
    • (2010) Blood , vol.115 , pp. 5026-5036
    • Isnardi, I.1    Ng, Y.-S.2    Menard, L.3    Meyers, G.4    Saadoun, D.5    Srdanovic, I.6    Samuels, J.7


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