메뉴 건너뛰기




Volumn 27, Issue 1, 2007, Pages 53-68

Similar CD19 dysregulation in two autoantibody-associated autoimmune diseases suggests a shared mechanism of B-cell tolerance loss

Author keywords

ANCA small vessel vasculitis; Autoantibodies; Autoimmunity; B lymphocytes; CD19; Systemic lupus erythematosus

Indexed keywords

AUTOANTIBODY; CD19 ANTIGEN; NEUTROPHIL CYTOPLASMIC ANTIBODY; RIBONUCLEOPROTEIN;

EID: 33846892500     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-006-9051-1     Document Type: Article
Times cited : (59)

References (56)
  • 1
    • 0032493059 scopus 로고    scopus 로고
    • Antibodies to DNA
    • Hahn BH: Antibodies to DNA. N Engl J Med 338(19):1359, 1998
    • (1998) N Engl J Med , vol.338 , Issue.19 , pp. 1359
    • Hahn, B.H.1
  • 2
    • 0348226819 scopus 로고    scopus 로고
    • Recent advances in the pathogenesis of lupus nephritis: Autoantibodies and B cells
    • Su W, Madaio MP: Recent advances in the pathogenesis of lupus nephritis: Autoantibodies and B cells. Semin Nephrol 23(6):564, 2003
    • (2003) Semin Nephrol , vol.23 , Issue.6 , pp. 564
    • Su, W.1    Madaio, M.P.2
  • 3
    • 0023878734 scopus 로고
    • Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis
    • Falk RJ, Jennette JC: Anti-neutrophil cytoplasmic autoantibodies with specificity for myeloperoxidase in patients with systemic vasculitis and idiopathic necrotizing and crescentic glomerulonephritis. N Engl J Med 318(25):1651, 1988
    • (1988) N Engl J Med , vol.318 , Issue.25 , pp. 1651
    • Falk, R.J.1    Jennette, J.C.2
  • 4
    • 0025353345 scopus 로고
    • Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3
    • Jennette JC, Hoidal JR, Falk RJ: Specificity of anti-neutrophil cytoplasmic autoantibodies for proteinase 3. Blood 75(11):2263, 1990
    • (1990) Blood , vol.75 , Issue.11 , pp. 2263
    • Jennette, J.C.1    Hoidal, J.R.2    Falk, R.J.3
  • 5
    • 0024389175 scopus 로고
    • Anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and vasculitis
    • Jennette JC, Wilkman AS, Falk RJ: Anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and vasculitis. Am J Pathol 135(5):921, 1989
    • (1989) Am J Pathol , vol.135 , Issue.5 , pp. 921
    • Jennette, J.C.1    Wilkman, A.S.2    Falk, R.J.3
  • 6
    • 0030725347 scopus 로고    scopus 로고
    • Small-vessel vasculitis
    • Jennette JC, Falk RJ: Small-vessel vasculitis. N Engl J Med 337(21):1512, 1997
    • (1997) N Engl J Med , vol.337 , Issue.21 , pp. 1512
    • Jennette, J.C.1    Falk, R.J.2
  • 8
    • 0025130164 scopus 로고
    • Clinical course of anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and systemic vasculitis. The Glomerular Disease Collaborative Network
    • Falk RJ, Hogan S, Carey TS, Jennette JC: Clinical course of anti-neutrophil cytoplasmic autoantibody-associated glomerulonephritis and systemic vasculitis. The Glomerular Disease Collaborative Network. Ann Intern Med 113(9):656, 1990
    • (1990) Ann Intern Med , vol.113 , Issue.9 , pp. 656
    • Falk, R.J.1    Hogan, S.2    Carey, T.S.3    Jennette, J.C.4
  • 9
    • 0030052126 scopus 로고    scopus 로고
    • Prognostic markers in patients with antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis
    • Hogan SL, Nachman PH, Wilkman AS, Jennette JC, Falk RJ: Prognostic markers in patients with antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis. J Am Soc Nephrol 7(1):23, 1996
    • (1996) J Am Soc Nephrol , vol.7 , Issue.1 , pp. 23
    • Hogan, S.L.1    Nachman, P.H.2    Wilkman, A.S.3    Jennette, J.C.4    Falk, R.J.5
  • 11
    • 0018887198 scopus 로고
    • Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus
    • Blaese RM, Grayson J, Steinberg AD: Increased immunoglobulin-secreting cells in the blood of patients with active systemic lupus erythematosus. Am J Med 69(3):345, 1980
    • (1980) Am J Med , vol.69 , Issue.3 , pp. 345
    • Blaese, R.M.1    Grayson, J.2    Steinberg, A.D.3
  • 13
    • 0020406405 scopus 로고
    • Relationship between reduced B cell susceptibility to IgM antibodies and reduced IgD-bearing B cells in patients with systemic lupus erythematosus
    • Suzuki H, Sakurami T, Imura H: Relationship between reduced B cell susceptibility to IgM antibodies and reduced IgD-bearing B cells in patients with systemic lupus erythematosus. Arthritis Rheum 25(12):1451, 1982
    • (1982) Arthritis Rheum , vol.25 , Issue.12 , pp. 1451
    • Suzuki, H.1    Sakurami, T.2    Imura, H.3
  • 14
    • 0029829026 scopus 로고    scopus 로고
    • B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events
    • Liossis SN, Kovacs B, Dennis G, Kammer GM, Tsokos GC: B cells from patients with systemic lupus erythematosus display abnormal antigen receptor-mediated early signal transduction events. J Clin Invest 98(11):2549, 1996
    • (1996) J Clin Invest , vol.98 , Issue.11 , pp. 2549
    • Liossis, S.N.1    Kovacs, B.2    Dennis, G.3    Kammer, G.M.4    Tsokos, G.C.5
  • 16
    • 0035020157 scopus 로고    scopus 로고
    • Expression of costimulatory molecules on peripheral blood lymphocytes of patients with systemic lupus erythematosus
    • Bijl M, Horst G, Limburg PC, Kallenberg CG: Expression of costimulatory molecules on peripheral blood lymphocytes of patients with systemic lupus erythematosus. Ann Rheum Dis 60(5):523, 2001
    • (2001) Ann Rheum Dis , vol.60 , Issue.5 , pp. 523
    • Bijl, M.1    Horst, G.2    Limburg, P.C.3    Kallenberg, C.G.4
  • 17
    • 17644434779 scopus 로고    scopus 로고
    • Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients
    • Folzenlogen D, Hofer MF, Leung DY, Freed JH, Newell MK: Analysis of CD80 and CD86 expression on peripheral blood B lymphocytes reveals increased expression of CD86 in lupus patients. Clin Immunol Immunopathol 83(3):199, 1997
    • (1997) Clin Immunol Immunopathol , vol.83 , Issue.3 , pp. 199
    • Folzenlogen, D.1    Hofer, M.F.2    Leung, D.Y.3    Freed, J.H.4    Newell, M.K.5
  • 20
    • 0025371375 scopus 로고
    • + B lymphocytes in systemic lupus erythematosus and rheumatoid arthritis
    • + B lymphocytes in systemic lupus erythematosus and rheumatoid arthritis. J Rheumatol 17(6):833, 1990
    • (1990) J Rheumatol , vol.17 , Issue.6 , pp. 833
    • Smith, H.R.1    Olson, R.R.2
  • 21
    • 0030784484 scopus 로고    scopus 로고
    • CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes
    • Inaoki M, Sato S, Weintraub BC, Goodnow CC, Tedder TF: CD19-regulated signaling thresholds control peripheral tolerance and autoantibody production in B lymphocytes. J Exp Med 186(11):1923, 1997
    • (1997) J Exp Med , vol.186 , Issue.11 , pp. 1923
    • Inaoki, M.1    Sato, S.2    Weintraub, B.C.3    Goodnow, C.C.4    Tedder, T.F.5
  • 22
    • 0030901968 scopus 로고    scopus 로고
    • The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity
    • Tedder TF, Inaoki M, Sato S: The CD19-CD21 complex regulates signal transduction thresholds governing humoral immunity and autoimmunity. Immunity 6(2):107, 1997
    • (1997) Immunity , vol.6 , Issue.2 , pp. 107
    • Tedder, T.F.1    Inaoki, M.2    Sato, S.3
  • 23
    • 0026758271 scopus 로고
    • The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules
    • Bradbury LE, Kansas GS, Levy S, Evans RL, Tedder TF: The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules. J Immunol 149(9):2841, 1992
    • (1992) J Immunol , vol.149 , Issue.9 , pp. 2841
    • Bradbury, L.E.1    Kansas, G.S.2    Levy, S.3    Evans, R.L.4    Tedder, T.F.5
  • 24
    • 0027258108 scopus 로고
    • The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13
    • Bradbury LE, Goldmacher VS, Tedder TF: The CD19 signal transduction complex of B lymphocytes. Deletion of the CD19 cytoplasmic domain alters signal transduction but not complex formation with TAPA-1 and Leu 13. J Immunol 151(6):2915, 1993
    • (1993) J Immunol , vol.151 , Issue.6 , pp. 2915
    • Bradbury, L.E.1    Goldmacher, V.S.2    Tedder, T.F.3
  • 25
    • 0030593030 scopus 로고    scopus 로고
    • C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity
    • Dempsey PW, Allison ME, Akkaraju S, Goodnow CC, Fearon DT: C3d of complement as a molecular adjuvant: Bridging innate and acquired immunity. Science 271(5247):348, 1996
    • (1996) Science , vol.271 , Issue.5247 , pp. 348
    • Dempsey, P.W.1    Allison, M.E.2    Akkaraju, S.3    Goodnow, C.C.4    Fearon, D.T.5
  • 26
    • 0034544489 scopus 로고    scopus 로고
    • Quantitative genetic variation in CD19 expression correlates with autoimmunity
    • Sato S, Hasegawa M, Fujimoto M, Tedder TF, Takehara K: Quantitative genetic variation in CD19 expression correlates with autoimmunity. J Immunol 165(11):6635, 2000
    • (2000) J Immunol , vol.165 , Issue.11 , pp. 6635
    • Sato, S.1    Hasegawa, M.2    Fujimoto, M.3    Tedder, T.F.4    Takehara, K.5
  • 27
    • 2642511623 scopus 로고    scopus 로고
    • Altered blood B lymphocyte homeostasis in systemic sclerosis: Expanded naive B cells and diminished but activated memory B cells
    • Sato S, Fujimoto M, Hasegawa M, Takehara K: Altered blood B lymphocyte homeostasis in systemic sclerosis: Expanded naive B cells and diminished but activated memory B cells. Arthritis Rheum 50(6):1918, 2004
    • (2004) Arthritis Rheum , vol.50 , Issue.6 , pp. 1918
    • Sato, S.1    Fujimoto, M.2    Hasegawa, M.3    Takehara, K.4
  • 29
    • 0036996358 scopus 로고    scopus 로고
    • Expansion of CD19(hi)CD21(lo/neg) B cells in common variable immunodeficiency (CVID) patients with autoimmune cytopenia
    • Warnatz K, Wehr C, Drager R, Schmidt S, Eibel H, Schlesier M, Peter HH: Expansion of CD19(hi)CD21(lo/neg) B cells in common variable immunodeficiency (CVID) patients with autoimmune cytopenia. Immunobiology 206(5):502, 2002
    • (2002) Immunobiology , vol.206 , Issue.5 , pp. 502
    • Warnatz, K.1    Wehr, C.2    Drager, R.3    Schmidt, S.4    Eibel, H.5    Schlesier, M.6    Peter, H.H.7
  • 30
    • 0026777352 scopus 로고
    • Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE
    • Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH: Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE. Arthritis Rheum 35(6):630, 1992
    • (1992) Arthritis Rheum , vol.35 , Issue.6 , pp. 630
    • Bombardier, C.1    Gladman, D.D.2    Urowitz, M.B.3    Caron, D.4    Chang, C.H.5
  • 31
    • 0024201978 scopus 로고    scopus 로고
    • Matsuo T, Hisanaga S, Yamaguchi Y, Shimokawa H, Nakano H: [Case report of a prenatal diagnosis of 46, XY, t(13q; 14q) mat, +18]. Fukuoka Igaku Zasshi 79(12):927, 1988
    • Matsuo T, Hisanaga S, Yamaguchi Y, Shimokawa H, Nakano H: [Case report of a prenatal diagnosis of 46, XY, t(13q; 14q) mat, +18]. Fukuoka Igaku Zasshi 79(12):927, 1988
  • 33
    • 0036134880 scopus 로고    scopus 로고
    • Low-affinity anti-Smith antigen B cells are regulated by anergy as opposed to developmental arrest or differentiation to B-1
    • Borrero M, Clarke SH: Low-affinity anti-Smith antigen B cells are regulated by anergy as opposed to developmental arrest or differentiation to B-1. J Immunol 168(1):13, 2002
    • (2002) J Immunol , vol.168 , Issue.1 , pp. 13
    • Borrero, M.1    Clarke, S.H.2
  • 34
    • 29244483707 scopus 로고    scopus 로고
    • Sequence analyses from single antigen-specific B lymphocytes using an mRNA capture plate
    • Arnold L, McCray S: Sequence analyses from single antigen-specific B lymphocytes using an mRNA capture plate. Am Biotechnol Lab 14, 2004
    • (2004) Am Biotechnol Lab , vol.14
    • Arnold, L.1    McCray, S.2
  • 35
    • 0034693394 scopus 로고    scopus 로고
    • Human immunoglobulin variable region gene analysis by single cell RT-PCR
    • Wang X, Stollar BD: Human immunoglobulin variable region gene analysis by single cell RT-PCR. J Immunol Methods 244(1-2):217, 2000
    • (2000) J Immunol Methods , vol.244 , Issue.1-2 , pp. 217
    • Wang, X.1    Stollar, B.D.2
  • 36
    • 32544437698 scopus 로고    scopus 로고
    • SoDA: Implementation of a 3D alignment algorithm for inference of antigen receptor recombinations
    • Volpe JM, Cowell LG, Kepler TB: SoDA: Implementation of a 3D alignment algorithm for inference of antigen receptor recombinations. Bioinformatics 22(4):438, 2006
    • (2006) Bioinformatics , vol.22 , Issue.4 , pp. 438
    • Volpe, J.M.1    Cowell, L.G.2    Kepler, T.B.3
  • 37
    • 31044440224 scopus 로고    scopus 로고
    • Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays
    • Li QZ, Xie C, Wu T, Mackay M, Aranow C, Putterman C, Mohan C: Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays. J Clin Invest 115(12):3428, 2005
    • (2005) J Clin Invest , vol.115 , Issue.12 , pp. 3428
    • Li, Q.Z.1    Xie, C.2    Wu, T.3    Mackay, M.4    Aranow, C.5    Putterman, C.6    Mohan, C.7
  • 38
    • 0018574137 scopus 로고
    • Identification of a clinical subset of systemic lupus erythematosus by antibodies to the SM antigen
    • Winn DM, Wolfe JF, Lindberg DA, Fristoe FH, Kingsland L, Sharp GC: Identification of a clinical subset of systemic lupus erythematosus by antibodies to the SM antigen. Arthritis Rheum 22(12):1334, 1979
    • (1979) Arthritis Rheum , vol.22 , Issue.12 , pp. 1334
    • Winn, D.M.1    Wolfe, J.F.2    Lindberg, D.A.3    Fristoe, F.H.4    Kingsland, L.5    Sharp, G.C.6
  • 39
    • 0035478494 scopus 로고    scopus 로고
    • Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjogren's syndrome
    • Bohnhorst JO, Bjorgan MB, Thoen JE, Natvig JB, Thompson KM: Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjogren's syndrome. J Immunol 167(7):3610, 2001
    • (2001) J Immunol , vol.167 , Issue.7 , pp. 3610
    • Bohnhorst, J.O.1    Bjorgan, M.B.2    Thoen, J.E.3    Natvig, J.B.4    Thompson, K.M.5
  • 40
    • 33748509736 scopus 로고    scopus 로고
    • A new memory CD27-IgG+B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation
    • Fecteau JF, Cote G, Neron S: A new memory CD27-IgG+B cell population in peripheral blood expressing VH genes with low frequency of somatic mutation. J Immunol 177(6):3728, 2006
    • (2006) J Immunol , vol.177 , Issue.6 , pp. 3728
    • Fecteau, J.F.1    Cote, G.2    Neron, S.3
  • 41
    • 0029063311 scopus 로고
    • Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
    • Brezinschek HP, Brezinschek RI, Lipsky PE: Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. J Immunol 155(1):190, 1995
    • (1995) J Immunol , vol.155 , Issue.1 , pp. 190
    • Brezinschek, H.P.1    Brezinschek, R.I.2    Lipsky, P.E.3
  • 42
    • 0345211476 scopus 로고    scopus 로고
    • Ig lambda and heavy chain gene usage in early untreated systemic lupus erythematosus suggests intensive B cell stimulation
    • Dorner T, Farner NL, Lipsky PE: Ig lambda and heavy chain gene usage in early untreated systemic lupus erythematosus suggests intensive B cell stimulation. J Immunol 163(2):1027, 1999
    • (1999) J Immunol , vol.163 , Issue.2 , pp. 1027
    • Dorner, T.1    Farner, N.L.2    Lipsky, P.E.3
  • 43
    • 0141427786 scopus 로고    scopus 로고
    • B cell activation leads to shedding of complement receptor type II (CR2/CD21)
    • Masilamani M, Kassahn D, Mikkat S, Glocker MO, Illges H: B cell activation leads to shedding of complement receptor type II (CR2/CD21). Eur J Immunol 33(9):2391, 2003
    • (2003) Eur J Immunol , vol.33 , Issue.9 , pp. 2391
    • Masilamani, M.1    Kassahn, D.2    Mikkat, S.3    Glocker, M.O.4    Illges, H.5
  • 44
    • 0026501713 scopus 로고
    • Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells
    • Ewert BH, Jennette JC, Falk RJ: Anti-myeloperoxidase antibodies stimulate neutrophils to damage human endothelial cells. Kidney Int 41(2):375, 1992
    • (1992) Kidney Int , vol.41 , Issue.2 , pp. 375
    • Ewert, B.H.1    Jennette, J.C.2    Falk, R.J.3
  • 45
    • 0036790387 scopus 로고    scopus 로고
    • Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice
    • Xiao H, Heeringa P, Hu P, Liu Z, Zhao M, Aratani Y, Maeda N, Falk RJ, Jennette JC: Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J Clin Invest 110(7):955, 2002
    • (2002) J Clin Invest , vol.110 , Issue.7 , pp. 955
    • Xiao, H.1    Heeringa, P.2    Hu, P.3    Liu, Z.4    Zhao, M.5    Aratani, Y.6    Maeda, N.7    Falk, R.J.8    Jennette, J.C.9
  • 47
    • 0035865056 scopus 로고    scopus 로고
    • Lupus-specific antiribonucleoprotein B cell tolerance in nonautoimmune mice is maintained by differentiation to B-1 and governed by B cell receptor signaling thresholds
    • Qian Y, Santiago C, Borrero M, Tedder TF, Clarke SH: Lupus-specific antiribonucleoprotein B cell tolerance in nonautoimmune mice is maintained by differentiation to B-1 and governed by B cell receptor signaling thresholds. J Immunol 166(4):2412, 2001
    • (2001) J Immunol , vol.166 , Issue.4 , pp. 2412
    • Qian, Y.1    Santiago, C.2    Borrero, M.3    Tedder, T.F.4    Clarke, S.H.5
  • 53
    • 33748472865 scopus 로고    scopus 로고
    • Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
    • Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell RA, Shlomchik MJ: Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity 25(3):417, 2006
    • (2006) Immunity , vol.25 , Issue.3 , pp. 417
    • Christensen, S.R.1    Shupe, J.2    Nickerson, K.3    Kashgarian, M.4    Flavell, R.A.5    Shlomchik, M.J.6
  • 54
    • 33645076274 scopus 로고    scopus 로고
    • TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE
    • Ehlers M, Fukuyama H, McGaha TL, Aderem A, Ravetch JV: TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE. J Exp Med 203(3):553, 2006
    • (2006) J Exp Med , vol.203 , Issue.3 , pp. 553
    • Ehlers, M.1    Fukuyama, H.2    McGaha, T.L.3    Aderem, A.4    Ravetch, J.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.